Inhibition of hepatic Niemann-Pick C1-like 1 improves hepatic insulin resistance

American Journal of Physiology - Endocrinology and Metabolism

Volumn 297, Issue 5, 2009, Pages

  Nomura, Mitsunori ^a   Ishii, Hideto ^a   Kawakami, Akio ^b   Yoshida, Masayuki ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Cholesterol transporter; Endoplasmic reticulum stress; Oxidative stress

Indexed keywords

EZETIMIBE; INSULIN; LIPID TRANSFER PROTEIN; PROTEIN KINASE B; PROTEIN NPC1L1; REACTIVE OXYGEN METABOLITE; SHORT HAIRPIN RNA; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR FKHR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; FATTY LIVER; GENETIC TRANSFECTION; GLUCOSE METABOLISM; HUMAN; HUMAN CELL; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPID STORAGE; LIVER CELL; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; ANTICHOLESTEREMIC AGENTS; AZETIDINES; BLOTTING, WESTERN; CELLS, CULTURED; CHOLESTEROL; DNA PRIMERS; ENDOPLASMIC RETICULUM; FATTY LIVER; GLUCOSE; GLUCOSE TOLERANCE TEST; HUMANS; INSULIN RESISTANCE; LIPID METABOLISM; LIVER; MALE; MEMBRANE TRANSPORT PROTEINS; PYRUVIC ACID; RATS; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA, MESSENGER; SUPEROXIDES; TRIGLYCERIDES;

EID: 70350468701     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00343.2009     Document Type: Article

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