Inactivation of NPC1L1 causes multiple lipid transport defects and protects against diet-induced hypercholesterolemia

Journal of Biological Chemistry

Volumn 280, Issue 13, 2005, Pages 12710-12720

  Davies, Joanna P ^a   Scott, Catherine ^a   Oishi, Kimihiko ^a   Liapis, Anastasia ^a   Ioannou, Yiannis A ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; CELLS; CHOLESTEROL; MATHEMATICAL MODELS; PLASMAS; RNA;

CAVEOLIN TRANSPORT; CELL LINES; SPHINGOLIPIDS; SUBCELLULAR LOCATION;

LIPIDS;

CAVEOLIN; CHOLESTEROL; GUANOSINE TRIPHOSPHATASE; LIPID; MESSENGER RNA; NIEMANN PICK C1 LIKE PROTEIN; PROTEIN; RAB PROTEIN; SPHINGOLIPID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL COMPARTMENTALIZATION; CELL LINE; CELL MEMBRANE; CELL STRAIN HEPG2; CELL TRANSPORT; CELL VACUOLE; CELLULAR DISTRIBUTION; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; DIET; FEMALE; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERCHOLESTEROLEMIA; HYPERLIPIDEMIA; KNOCKOUT MOUSE; LIPID TRANSPORT; LIVER; MALE; MODEL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTECTION; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REGULATORY MECHANISM; SMALL INTESTINE; SPECIES DIFFERENCE; WILD TYPE;

ANIMALS; BIOLOGICAL TRANSPORT; BLOTTING, WESTERN; CAVEOLIN 1; CAVEOLINS; CELL LINE; CELL LINE, TUMOR; CELL MEMBRANE; CHOLESTEROL; COS CELLS; DIETARY FATS; ENDOCYTOSIS; FEMALE; GENETIC VECTORS; HUMANS; HYPERCHOLESTEROLEMIA; HYPERLIPIDEMIAS; INTESTINE, SMALL; LIPID METABOLISM; LIPOPROTEINS, LDL; LIVER; LUCIFERASES; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, FLUORESCENCE; POLYMERASE CHAIN REACTION; PROTEINS; RAB5 GTP-BINDING PROTEINS; RECOMBINATION, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPECIES SPECIFICITY; TIME FACTORS; TISSUE DISTRIBUTION;

EID: 16844376244     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M409110200     Document Type: Article

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