-
1
-
-
22344452893
-
The natural history of nonalcoholic fatty liver disease: a population-based cohort study
-
Adams L.A., Lymp J.F., St Sauver J., Sanderson S.O., Lindor K.D., Feldstein A., and Angulo P. The natural history of nonalcoholic fatty liver disease: a population-based cohort study. Gastroenterology 129 (2005) 113-121
-
(2005)
Gastroenterology
, vol.129
, pp. 113-121
-
-
Adams, L.A.1
Lymp, J.F.2
St Sauver, J.3
Sanderson, S.O.4
Lindor, K.D.5
Feldstein, A.6
Angulo, P.7
-
2
-
-
10744221008
-
Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption
-
Altmann S.W., Davis Jr. H.R., Zhu L.J., Yao X., Hoos L.M., Tetzloff G., Iyer S.P., Maguire M., Golovko A., Zeng M., Wang L., Murgolo N., and Graziano M.P. Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption. Science 303 (2004) 1201-1204
-
(2004)
Science
, vol.303
, pp. 1201-1204
-
-
Altmann, S.W.1
Davis Jr., H.R.2
Zhu, L.J.3
Yao, X.4
Hoos, L.M.5
Tetzloff, G.6
Iyer, S.P.7
Maguire, M.8
Golovko, A.9
Zeng, M.10
Wang, L.11
Murgolo, N.12
Graziano, M.P.13
-
3
-
-
0037129380
-
Nonalcoholic fatty liver disease
-
Angulo P. Nonalcoholic fatty liver disease. N. Engl. J. Med. 346 (2002) 1221-1231
-
(2002)
N. Engl. J. Med.
, vol.346
, pp. 1221-1231
-
-
Angulo, P.1
-
4
-
-
33644955272
-
Mouse models in non-alcoholic fatty liver disease and steatohepatitis research
-
Anstee Q.M., and Goldin R.D. Mouse models in non-alcoholic fatty liver disease and steatohepatitis research. Int. J. Exp. Pathol. 87 (2006) 1-16
-
(2006)
Int. J. Exp. Pathol.
, vol.87
, pp. 1-16
-
-
Anstee, Q.M.1
Goldin, R.D.2
-
5
-
-
33746930302
-
Effect of insulin-sensitizing agents in combination with ezetimibe, and valsartan in rats with non-alcoholic fatty liver disease
-
Assy N., Grozovski M., Bersudsky I., Szvalb S., and Hussein O. Effect of insulin-sensitizing agents in combination with ezetimibe, and valsartan in rats with non-alcoholic fatty liver disease. World J. Gastroenterol. 12 (2006) 4369-4376
-
(2006)
World J. Gastroenterol.
, vol.12
, pp. 4369-4376
-
-
Assy, N.1
Grozovski, M.2
Bersudsky, I.3
Szvalb, S.4
Hussein, O.5
-
6
-
-
34147137671
-
Lysosomal unesterified cholesterol content correlates with liver cell death in murine Niemann-Pick type C disease
-
Beltroy E.P., Liu B., Dietschy J.M., and Turley S.D. Lysosomal unesterified cholesterol content correlates with liver cell death in murine Niemann-Pick type C disease. J. Lipid. Res. 48 (2007) 869-881
-
(2007)
J. Lipid. Res.
, vol.48
, pp. 869-881
-
-
Beltroy, E.P.1
Liu, B.2
Dietschy, J.M.3
Turley, S.D.4
-
7
-
-
0027405261
-
Enzymatic determination of triglyceride, free cholesterol, and total cholesterol in tissue lipid extracts
-
Carr T.P., Andresen C.J., and Rudel L.L. Enzymatic determination of triglyceride, free cholesterol, and total cholesterol in tissue lipid extracts. Clin. Biochem. 26 (1993) 39-42
-
(1993)
Clin. Biochem.
, vol.26
, pp. 39-42
-
-
Carr, T.P.1
Andresen, C.J.2
Rudel, L.L.3
-
8
-
-
32444441330
-
Multiple rare variants in NPC1L1 associated with reduced sterol absorption and plasma low-density lipoprotein levels
-
Cohen J.C., Pertsemlidis A., Fahmi S., Esmail S., Vega G.L., Grundy S.M., and Hobbs H.H. Multiple rare variants in NPC1L1 associated with reduced sterol absorption and plasma low-density lipoprotein levels. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 1810-1815
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 1810-1815
-
-
Cohen, J.C.1
Pertsemlidis, A.2
Fahmi, S.3
Esmail, S.4
Vega, G.L.5
Grundy, S.M.6
Hobbs, H.H.7
-
9
-
-
16844376244
-
Inactivation of NPC1L1 causes multiple lipid transport defects and protects against diet-induced hypercholesterolemia
-
Davies J.P., Scott C., Oishi K., Liapis A., and Ioannou Y.A. Inactivation of NPC1L1 causes multiple lipid transport defects and protects against diet-induced hypercholesterolemia. J. Biol. Chem. 280 (2005) 12710-12720
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 12710-12720
-
-
Davies, J.P.1
Scott, C.2
Oishi, K.3
Liapis, A.4
Ioannou, Y.A.5
-
10
-
-
4043124013
-
Niemann-Pick C1 Like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis
-
Davis Jr. H.R., Zhu L.J., Hoos L.M., Tetzloff G., Maguire M., Liu J., Yao X., Iyer S.P., Lam M.H., Lund E.G., Detmers P.A., Graziano M.P., and Altmann S.W. Niemann-Pick C1 Like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis. J. Biol. Chem. 279 (2004) 33586-33592
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 33586-33592
-
-
Davis Jr., H.R.1
Zhu, L.J.2
Hoos, L.M.3
Tetzloff, G.4
Maguire, M.5
Liu, J.6
Yao, X.7
Iyer, S.P.8
Lam, M.H.9
Lund, E.G.10
Detmers, P.A.11
Graziano, M.P.12
Altmann, S.W.13
-
11
-
-
26444524411
-
Cholesterol-induced macrophage apoptosis requires ER stress pathways and engagement of the type A scavenger receptor
-
Devries-Seimon T., Li Y., Yao P.M., Stone E., Wang Y., Davis R.J., Flavell R., and Tabas I. Cholesterol-induced macrophage apoptosis requires ER stress pathways and engagement of the type A scavenger receptor. J. Cell Biol. 171 (2005) 61-73
-
(2005)
J. Cell Biol.
, vol.171
, pp. 61-73
-
-
Devries-Seimon, T.1
Li, Y.2
Yao, P.M.3
Stone, E.4
Wang, Y.5
Davis, R.J.6
Flavell, R.7
Tabas, I.8
-
12
-
-
33644547706
-
Nonalcoholic fatty liver disease: from steatosis to cirrhosis
-
Farrell G.C., and Larter C.Z. Nonalcoholic fatty liver disease: from steatosis to cirrhosis. Hepatology 43 (2006) S99-S112
-
(2006)
Hepatology
, vol.43
-
-
Farrell, G.C.1
Larter, C.Z.2
-
13
-
-
20444371945
-
The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1)
-
Garcia-Calvo M., Lisnock J., Bull H.G., Hawes B.E., Burnett D.A., Braun M.P., Crona J.H., Davis Jr. H.R., Dean D.C., Detmers P.A., Graziano M.P., Hughes M., Macintyre D.E., Ogawa A., O'Neill K., Iyer S.P., Shevell D.E., Smith M.M., Tang Y.S., Makarewicz A.M., Ujjainwalla F., Altmann S.W., Chapman K.T., and Thornberry N.A. The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1). Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 8132-8137
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 8132-8137
-
-
Garcia-Calvo, M.1
Lisnock, J.2
Bull, H.G.3
Hawes, B.E.4
Burnett, D.A.5
Braun, M.P.6
Crona, J.H.7
Davis Jr., H.R.8
Dean, D.C.9
Detmers, P.A.10
Graziano, M.P.11
Hughes, M.12
Macintyre, D.E.13
Ogawa, A.14
O'Neill, K.15
Iyer, S.P.16
Shevell, D.E.17
Smith, M.M.18
Tang, Y.S.19
Makarewicz, A.M.20
Ujjainwalla, F.21
Altmann, S.W.22
Chapman, K.T.23
Thornberry, N.A.24
more..
-
14
-
-
33748983728
-
Unexpected beneficial effect in the use of ezetimibe in non-alcoholic fatty liver disease
-
Hughes E.A., Tracey I., Singhal S., and Patel J. Unexpected beneficial effect in the use of ezetimibe in non-alcoholic fatty liver disease. Med. Hypotheses 67 (2006) 1463-1464
-
(2006)
Med. Hypotheses
, vol.67
, pp. 1463-1464
-
-
Hughes, E.A.1
Tracey, I.2
Singhal, S.3
Patel, J.4
-
15
-
-
29144492714
-
The role of leptin in progression of non-alcoholic fatty liver disease
-
Ikejima K., Okumura K., Lang T., Honda H., Abe W., Yamashina S., Enomoto N., Takei Y., and Sato N. The role of leptin in progression of non-alcoholic fatty liver disease. Hepatol. Res. 33 (2005) 151-154
-
(2005)
Hepatol. Res.
, vol.33
, pp. 151-154
-
-
Ikejima, K.1
Okumura, K.2
Lang, T.3
Honda, H.4
Abe, W.5
Yamashina, S.6
Enomoto, N.7
Takei, Y.8
Sato, N.9
-
16
-
-
17844403507
-
Mild hepatic fibrosis in cholesterol and sodium cholate diet-fed rats
-
Jeong W.I., Jeong D.H., Do S.H., Kim Y.K., Park H.Y., Kwon O.D., Kim T.H., and Jeong K.S. Mild hepatic fibrosis in cholesterol and sodium cholate diet-fed rats. J. Vet. Med. Sci. 67 (2005) 235-242
-
(2005)
J. Vet. Med. Sci.
, vol.67
, pp. 235-242
-
-
Jeong, W.I.1
Jeong, D.H.2
Do, S.H.3
Kim, Y.K.4
Park, H.Y.5
Kwon, O.D.6
Kim, T.H.7
Jeong, K.S.8
-
17
-
-
0344010170
-
Rodent nutritional model of non-alcoholic steatohepatitis: species, strain and sex difference studies
-
Kirsch R., Clarkson V., Shephard E.G., Marais D.A., Jaffer M.A., Woodburne V.E., Kirsch R.E., and Hall Pde L. Rodent nutritional model of non-alcoholic steatohepatitis: species, strain and sex difference studies. J. Gastroenterol. Hepatol. 18 (2003) 1272-1282
-
(2003)
J. Gastroenterol. Hepatol.
, vol.18
, pp. 1272-1282
-
-
Kirsch, R.1
Clarkson, V.2
Shephard, E.G.3
Marais, D.A.4
Jaffer, M.A.5
Woodburne, V.E.6
Kirsch, R.E.7
Hall Pde, L.8
-
18
-
-
0348050047
-
Ezetimibe: a first-in-class, novel cholesterol absorption inhibitor
-
Lipka L.J. Ezetimibe: a first-in-class, novel cholesterol absorption inhibitor. Cardiovasc. Drug. Rev. 21 (2003) 293-312
-
(2003)
Cardiovasc. Drug. Rev.
, vol.21
, pp. 293-312
-
-
Lipka, L.J.1
-
19
-
-
33747626511
-
Mitochondrial free cholesterol loading sensitizes to TNF- and Fas-mediated steatohepatitis
-
Mari M., Caballero F., Colell A., Morales A., Caballeria J., Fernandez A., Enrich C., Fernandez-Checa J.C., and Garcia-Ruiz C. Mitochondrial free cholesterol loading sensitizes to TNF- and Fas-mediated steatohepatitis. Cell Metab. 4 (2006) 185-198
-
(2006)
Cell Metab.
, vol.4
, pp. 185-198
-
-
Mari, M.1
Caballero, F.2
Colell, A.3
Morales, A.4
Caballeria, J.5
Fernandez, A.6
Enrich, C.7
Fernandez-Checa, J.C.8
Garcia-Ruiz, C.9
-
20
-
-
0036718446
-
Nonalcoholic fatty liver disease: pathogenesis and the role of antioxidants
-
Mehta K., Van Thiel D.H., Shah N., and Mobarhan S. Nonalcoholic fatty liver disease: pathogenesis and the role of antioxidants. Nutr. Rev. 60 (2002) 289-293
-
(2002)
Nutr. Rev.
, vol.60
, pp. 289-293
-
-
Mehta, K.1
Van Thiel, D.H.2
Shah, N.3
Mobarhan, S.4
-
21
-
-
33644672230
-
Unraveling the temporal pattern of diet-induced insulin resistance in individual organs and cardiac dysfunction in C57BL/6 mice
-
Park S.Y., Cho Y.R., Kim H.J., Higashimori T., Danton C., Lee M.K., Dey A., Rothermel B., Kim Y.B., Kalinowski A., Russell K.S., and Kim J.K. Unraveling the temporal pattern of diet-induced insulin resistance in individual organs and cardiac dysfunction in C57BL/6 mice. Diabetes 54 (2005) 3530-3540
-
(2005)
Diabetes
, vol.54
, pp. 3530-3540
-
-
Park, S.Y.1
Cho, Y.R.2
Kim, H.J.3
Higashimori, T.4
Danton, C.5
Lee, M.K.6
Dey, A.7
Rothermel, B.8
Kim, Y.B.9
Kalinowski, A.10
Russell, K.S.11
Kim, J.K.12
-
22
-
-
0037221394
-
Determinants of the association of overweight with elevated serum alanine aminotransferase activity in the United States
-
Ruhl C.E., and Everhart J.E. Determinants of the association of overweight with elevated serum alanine aminotransferase activity in the United States. Gastroenterology 124 (2003) 71-79
-
(2003)
Gastroenterology
, vol.124
, pp. 71-79
-
-
Ruhl, C.E.1
Everhart, J.E.2
-
23
-
-
1442335817
-
Ezetimibe effectively reduces plasma plant sterols in patients with sitosterolemia
-
Salen G., von Bergmann K., Lutjohann D., Kwiterovich P., Kane J., Patel S.B., Musliner T., Stein P., and Musser B. Ezetimibe effectively reduces plasma plant sterols in patients with sitosterolemia. Circulation 109 (2004) 966-971
-
(2004)
Circulation
, vol.109
, pp. 966-971
-
-
Salen, G.1
von Bergmann, K.2
Lutjohann, D.3
Kwiterovich, P.4
Kane, J.5
Patel, S.B.6
Musliner, T.7
Stein, P.8
Musser, B.9
-
24
-
-
33947102613
-
The molecular mechanisms underlying the reduction of low density lipoprotein apoB-100 by ezetimibe plus simvastatin
-
Telford D.E., Sutherland B.G., Edwards J.Y., Andrews J.D., Barrett P.H., and Huff M.W. The molecular mechanisms underlying the reduction of low density lipoprotein apoB-100 by ezetimibe plus simvastatin. J. Lipid. Res. 48 (2007) 699-708
-
(2007)
J. Lipid. Res.
, vol.48
, pp. 699-708
-
-
Telford, D.E.1
Sutherland, B.G.2
Edwards, J.Y.3
Andrews, J.D.4
Barrett, P.H.5
Huff, M.W.6
-
25
-
-
0030807358
-
Diet-induced obese mice develop peripheral, but not central, resistance to leptin
-
Van Heek M., Compton D.S., France C.F., Tedesco R.P., Fawzi A.B., Graziano M.P., Sybertz E.J., Strader C.D., and Davis Jr. H.R. Diet-induced obese mice develop peripheral, but not central, resistance to leptin. J. Clin. Invest. 99 (1997) 385-390
-
(1997)
J. Clin. Invest.
, vol.99
, pp. 385-390
-
-
Van Heek, M.1
Compton, D.S.2
France, C.F.3
Tedesco, R.P.4
Fawzi, A.B.5
Graziano, M.P.6
Sybertz, E.J.7
Strader, C.D.8
Davis Jr., H.R.9
-
26
-
-
0034991315
-
Ezetimibe, a potent cholesterol absorption inhibitor, normalizes combined dyslipidemia in obese hyperinsulinemic hamsters
-
van Heek M., Austin T.M., Farley C., Cook J.A., Tetzloff G.G., and Davis H.R. Ezetimibe, a potent cholesterol absorption inhibitor, normalizes combined dyslipidemia in obese hyperinsulinemic hamsters. Diabetes 50 (2001) 1330-1335
-
(2001)
Diabetes
, vol.50
, pp. 1330-1335
-
-
van Heek, M.1
Austin, T.M.2
Farley, C.3
Cook, J.A.4
Tetzloff, G.G.5
Davis, H.R.6
-
27
-
-
0035831089
-
The cholesterol absorption inhibitor, ezetimibe, decreases diet-induced hypercholesterolemia in monkeys
-
van Heek M., Compton D.S., and Davis H.R. The cholesterol absorption inhibitor, ezetimibe, decreases diet-induced hypercholesterolemia in monkeys. Eur. J. Pharmacol. 415 (2001) 79-84
-
(2001)
Eur. J. Pharmacol.
, vol.415
, pp. 79-84
-
-
van Heek, M.1
Compton, D.S.2
Davis, H.R.3
-
28
-
-
30944451788
-
Saturated fatty acids promote endoplasmic reticulum stress and liver injury in rats with hepatic steatosis
-
Wang D., Wei Y., and Pagliassotti M.J. Saturated fatty acids promote endoplasmic reticulum stress and liver injury in rats with hepatic steatosis. Endocrinology 147 (2006) 943-951
-
(2006)
Endocrinology
, vol.147
, pp. 943-951
-
-
Wang, D.1
Wei, Y.2
Pagliassotti, M.J.3
|