-
1
-
-
0032489093
-
Orexins and orexin receptors: A family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior
-
Sakurai, T.; Amemiya, A.; Ishii, M.; Matsuzaki, I.; Chemelli, R.M.; Tanaka, H.; Williams, S.C.; Richardson, J.A.; Kozlowski, G.P.; Wilson, S.; Arch, J.R.; Buckingham, R.E.; Haynes, A.C.; Carr, S.A.; Annan, R.S.; McNulty, D.E.; Liu, W.S.; Terrett, J.A.; Elshourbagy, N.A.; Bergsma, D.J.; Yanagisawa, M. Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell, 1998, 92, 573-585.
-
(1998)
Cell
, vol.92
, pp. 573-585
-
-
Sakurai, T.1
Amemiya, A.2
Ishii, M.3
Matsuzaki, I.4
Chemelli, R.M.5
Tanaka, H.6
Williams, S.C.7
Richardson, J.A.8
Kozlowski, G.P.9
Wilson, S.10
Arch, J.R.11
Buckingham, R.E.12
Haynes, A.C.13
Carr, S.A.14
Annan, R.S.15
McNulty, D.E.16
Liu, W.S.17
Terrett, J.A.18
Elshourbagy, N.A.19
Bergsma, D.J.20
Yanagisawa, M.21
more..
-
2
-
-
0008390266
-
The hypocretins: Hypothalamus-specific peptides with neuroexcitatory activity
-
de Lecea, L.; Kilduff, T.S.; Peyron, C.; Gao, X.; Foye, P.E.; Danielson, P.E.; Fukuhara, C.; Battenberg, E.L.; Gautvik, V.T.; Bartlett, F.S., 2nd; Frankel, W.N.; van den Pol, A.N.; Bloom, F.E.; Gautvik, K.M.; Sutcliffe, J.G. The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity. Proc. Natl. Acad. Sci. USA, 1998, 95, 322-327.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 322-327
-
-
de Lecea, L.1
Kilduff, T.S.2
Peyron, C.3
Gao, X.4
Foye, P.E.5
Danielson, P.E.6
Fukuhara, C.7
Battenberg, E.L.8
Gautvik, V.T.9
Bartlett 2nd, F.S.10
Frankel, W.N.11
van den Pol, A.N.12
Bloom, F.E.13
Gautvik, K.M.14
Sutcliffe, J.G.15
-
3
-
-
0042565939
-
Orexin receptor type-1 couples exclusively to pertussis toxin-insensitive G-proteins, while orexin receptor type-2 couples to both pertussis toxin-sensitive and - insensitive G-proteins
-
Zhu, Y.; Miwa, Y.; Yamanaka, A.; Yada, T.; Shibahara, M.; Abe, Y.; Sakurai, T.; Goto, K. Orexin receptor type-1 couples exclusively to pertussis toxin-insensitive G-proteins, while orexin receptor type-2 couples to both pertussis toxin-sensitive and - insensitive G-proteins. J. Pharmacol. Sci., 2003, 92, 259-266.
-
(2003)
J. Pharmacol. Sci
, vol.92
, pp. 259-266
-
-
Zhu, Y.1
Miwa, Y.2
Yamanaka, A.3
Yada, T.4
Shibahara, M.5
Abe, Y.6
Sakurai, T.7
Goto, K.8
-
4
-
-
0033535747
-
Distribution of orexin neurons in the adult rat brain
-
Nambu, T.; Sakurai, T.; Mizukami, K.; Hosoya, Y.; Yanagisawa, M.; Goto, K. Distribution of orexin neurons in the adult rat brain. Brain Res., 1999, 827, 243-260.
-
(1999)
Brain Res
, vol.827
, pp. 243-260
-
-
Nambu, T.1
Sakurai, T.2
Mizukami, K.3
Hosoya, Y.4
Yanagisawa, M.5
Goto, K.6
-
5
-
-
0032402181
-
Neurons containing hypocretin (orexin) project to multiple neuronal systems
-
Peyron, C.; Tighe, D.K.; van den Pol, A.N.; de Lecea, L.; Heller, H.C.; Sutcliffe, J.G.; Kilduff, T.S. Neurons containing hypocretin (orexin) project to multiple neuronal systems. J. Neurosci., 1998, 18, 9996-10015.
-
(1998)
J. Neurosci
, vol.18
, pp. 9996-10015
-
-
Peyron, C.1
Tighe, D.K.2
van den Pol, A.N.3
de Lecea, L.4
Heller, H.C.5
Sutcliffe, J.G.6
Kilduff, T.S.7
-
6
-
-
0033582175
-
Orexins, orexigenic hypothalamic peptides, interact with autonomic, neuroendocrine and neuroregulatory systems
-
Date, Y.; Ueta, Y.; Yamashita, H.; Yamaguchi, H.; Matsukura, S.; Kangawa, K.; Sakurai, T.; Yanagisawa, M.; Nakazato, M. Orexins, orexigenic hypothalamic peptides, interact with autonomic, neuroendocrine and neuroregulatory systems. Proc. Natl. Acad. Sci. USA, 1999, 96, 748-753.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 748-753
-
-
Date, Y.1
Ueta, Y.2
Yamashita, H.3
Yamaguchi, H.4
Matsukura, S.5
Kangawa, K.6
Sakurai, T.7
Yanagisawa, M.8
Nakazato, M.9
-
7
-
-
0033561178
-
Hypothalamic hypocretin (orexin): Robust innervation of the spinal cord
-
van den Pol, A.N. Hypothalamic hypocretin (orexin): robust innervation of the spinal cord. J. Neurosci., 1999, 19, 3171-3182.
-
(1999)
J. Neurosci
, vol.19
, pp. 3171-3182
-
-
van den Pol, A.N.1
-
8
-
-
0032582716
-
Distribution of orexin receptor mRNA in the rat brain
-
Trivedi, P.; Yu, H.; MacNeil, D.J.; Van der Ploeg, L.H.; Guan, X.M. Distribution of orexin receptor mRNA in the rat brain. FEBS Lett., 1998, 438, 71-75.
-
(1998)
FEBS Lett
, vol.438
, pp. 71-75
-
-
Trivedi, P.1
Yu, H.2
MacNeil, D.J.3
Van der Ploeg, L.H.4
Guan, X.M.5
-
9
-
-
0033921449
-
Differential distribution and regulation of OX1 and OX2 orexin/hypocretin receptor messenger RNA in the brain upon fasting
-
Lu, X.Y.; Bagnol, D.; Burke, S.; Akil, H.; Watson, S.J. Differential distribution and regulation of OX1 and OX2 orexin/hypocretin receptor messenger RNA in the brain upon fasting. Horm. Behav., 2000, 37, 335-344.
-
(2000)
Horm. Behav
, vol.37
, pp. 335-344
-
-
Lu, X.Y.1
Bagnol, D.2
Burke, S.3
Akil, H.4
Watson, S.J.5
-
10
-
-
0035908286
-
Differential expression of orexin receptors 1 and 2 in the rat brain
-
Marcus, J.N.; Aschkenasi, C.J.; Lee, C.E.; Chemelli, R.M.; Saper, C.B.; Yanagisawa, M.; Elmquist, J.K. Differential expression of orexin receptors 1 and 2 in the rat brain. J. Comp. Neurol., 2001, 435, 6-25.
-
(2001)
J. Comp. Neurol
, vol.435
, pp. 6-25
-
-
Marcus, J.N.1
Aschkenasi, C.J.2
Lee, C.E.3
Chemelli, R.M.4
Saper, C.B.5
Yanagisawa, M.6
Elmquist, J.K.7
-
11
-
-
0031912090
-
Genetic and familial aspects of narcolepsy
-
Mignot, E. Genetic and familial aspects of narcolepsy. Neurology, 1998, 50, S16-S22.
-
(1998)
Neurology
, vol.50
-
-
Mignot, E.1
-
12
-
-
0033588184
-
Narcolepsy in orexin knockout mice: Molecular genetics of sleep regulation
-
Chemelli, R.M.; Willie, J.T.; Sinton, C.M.; Elmquist, J.K.; Scammell, T.; Lee, C.; Richardson, J.A.; Williams, S.C.; Xiong, Y.; Kisanuki, Y.; Fitch, T.E.; Nakazato, M.; Hammer, R.E.; Saper, C.B.; Yanagisawa, M. Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation. Cell, 1999, 98, 437-451.
-
(1999)
Cell
, vol.98
, pp. 437-451
-
-
Chemelli, R.M.1
Willie, J.T.2
Sinton, C.M.3
Elmquist, J.K.4
Scammell, T.5
Lee, C.6
Richardson, J.A.7
Williams, S.C.8
Xiong, Y.9
Kisanuki, Y.10
Fitch, T.E.11
Nakazato, M.12
Hammer, R.E.13
Saper, C.B.14
Yanagisawa, M.15
-
13
-
-
0033529520
-
The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene
-
Lin, L.; Faraco, J.; Li, R.; Kadotani, H.; Rogers, W.; Lin, X.; Qiu, X.; de Jong, P.J.; Nishino, S.; Mignot, E. The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene. Cell, 1999, 98, 365-376.
-
(1999)
Cell
, vol.98
, pp. 365-376
-
-
Lin, L.1
Faraco, J.2
Li, R.3
Kadotani, H.4
Rogers, W.5
Lin, X.6
Qiu, X.7
de Jong, P.J.8
Nishino, S.9
Mignot, E.10
-
14
-
-
0036791834
-
The role of cerebrospinal fluid hypocretin measurement in the diagnosis of narcolepsy and other hypersomnias
-
Mignot, E.; Lammers, G.J.; Ripley, B.; Okun, M.; Nevsimalova, S.; Overeem, S.; Vankova, J.; Black, J.; Harsh, J.; Bassetti, C.; Schrader, H.; Nishino, S. The role of cerebrospinal fluid hypocretin measurement in the diagnosis of narcolepsy and other hypersomnias. Arch. Neurol., 2002, 59, 1553-1562.
-
(2002)
Arch. Neurol
, vol.59
, pp. 1553-1562
-
-
Mignot, E.1
Lammers, G.J.2
Ripley, B.3
Okun, M.4
Nevsimalova, S.5
Overeem, S.6
Vankova, J.7
Black, J.8
Harsh, J.9
Bassetti, C.10
Schrader, H.11
Nishino, S.12
-
15
-
-
0033826856
-
A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains
-
Peyron, C.; Faraco, J.; Rogers, W.; Ripley, B.; Overeem, S.; Charnay, Y.; Nevsimalova, S.; Aldrich, M.; Reynolds, D.; Albin, R.; Li, R.; Hungs, M.; Pedrazzoli, M.; Padigaru, M.; Kucherlapati, M.; Fan, J.; Maki, R.; Lammers, G.J.; Bouras, C.; Kucherlapati, R.; Nishino, S.; Mignot, E. A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains. Nat. Med., 2000, 6, 991-997.
-
(2000)
Nat. Med
, vol.6
, pp. 991-997
-
-
Peyron, C.1
Faraco, J.2
Rogers, W.3
Ripley, B.4
Overeem, S.5
Charnay, Y.6
Nevsimalova, S.7
Aldrich, M.8
Reynolds, D.9
Albin, R.10
Li, R.11
Hungs, M.12
Pedrazzoli, M.13
Padigaru, M.14
Kucherlapati, M.15
Fan, J.16
Maki, R.17
Lammers, G.J.18
Bouras, C.19
Kucherlapati, R.20
Nishino, S.21
Mignot, E.22
more..
-
16
-
-
0033710848
-
Reduced number of hypocretin neurons in human narcolepsy
-
Thannickal, T.C.; Moore, R.Y.; Nienhuis, R.; Ramanathan, L.; Gulyani, S.; Aldrich, M.; Cornford, M.; Siegel, J.M. Reduced number of hypocretin neurons in human narcolepsy. Neuron, 2000, 27, 469-474.
-
(2000)
Neuron
, vol.27
, pp. 469-474
-
-
Thannickal, T.C.1
Moore, R.Y.2
Nienhuis, R.3
Ramanathan, L.4
Gulyani, S.5
Aldrich, M.6
Cornford, M.7
Siegel, J.M.8
-
17
-
-
24944518715
-
Concomitant loss of dynorphin, NARP, and orexin in narcolepsy
-
Crocker, A.; Espana, R.A.; Papadopoulou, M.; Saper, C.B.; Faraco, J.; Sakurai, T.; Honda, M.; Mignot, E.; Scammell, T.E. Concomitant loss of dynorphin, NARP, and orexin in narcolepsy. Neurology, 2005, 65, 1184-1188.
-
(2005)
Neurology
, vol.65
, pp. 1184-1188
-
-
Crocker, A.1
Espana, R.A.2
Papadopoulou, M.3
Saper, C.B.4
Faraco, J.5
Sakurai, T.6
Honda, M.7
Mignot, E.8
Scammell, T.E.9
-
18
-
-
0031861061
-
Genetic studies in the sleep disorder narcolepsy
-
Kadotani, H.; Faraco, J.; Mignot, E. Genetic studies in the sleep disorder narcolepsy. Genome Res., 1998, 8, 427-434.
-
(1998)
Genome Res
, vol.8
, pp. 427-434
-
-
Kadotani, H.1
Faraco, J.2
Mignot, E.3
-
19
-
-
0038724250
-
Distinct narcolepsy syndromes in Orexin receptor-2 and Orexin null mice: Molecular genetic dissection of Non-REM and REM sleep regulatory processes
-
Willie, J.T.; Chemelli, R.M.; Sinton, C.M.; Tokita, S.; Williams, S.C.; Kisanuki, Y.Y.; Marcus, J.N.; Lee, C.; Elmquist, J.K.; Kohlmeier, K.A.; Leonard, C.S.; Richardson, J.A.; Hammer, R.E.; Yanagisawa, M. Distinct narcolepsy syndromes in Orexin receptor-2 and Orexin null mice: molecular genetic dissection of Non-REM and REM sleep regulatory processes. Neuron, 2003, 38, 715-730.
-
(2003)
Neuron
, vol.38
, pp. 715-730
-
-
Willie, J.T.1
Chemelli, R.M.2
Sinton, C.M.3
Tokita, S.4
Williams, S.C.5
Kisanuki, Y.Y.6
Marcus, J.N.7
Lee, C.8
Elmquist, J.K.9
Kohlmeier, K.A.10
Leonard, C.S.11
Richardson, J.A.12
Hammer, R.E.13
Yanagisawa, M.14
-
20
-
-
0034920691
-
To eat or to sleep? Orexin in the regulation of feeding and wakefulness
-
Willie, J.T.; Chemelli, R.M.; Sinton, C.M.; Yanagisawa, M. To eat or to sleep? Orexin in the regulation of feeding and wakefulness. Annu. Rev. Neurosci., 2001, 24, 429-458.
-
(2001)
Annu. Rev. Neurosci
, vol.24
, pp. 429-458
-
-
Willie, J.T.1
Chemelli, R.M.2
Sinton, C.M.3
Yanagisawa, M.4
-
21
-
-
0034992322
-
Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity
-
Hara, J.; Beuckmann, C.T.; Nambu, T.; Willie, J.T.; Chemelli, R.M.; Sinton, C.M.; Sugiyama, F.; Yagami, K.; Goto, K.; Yanagisawa, M.; Sakurai, T. Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity. Neuron, 2001, 30, 345-354.
-
(2001)
Neuron
, vol.30
, pp. 345-354
-
-
Hara, J.1
Beuckmann, C.T.2
Nambu, T.3
Willie, J.T.4
Chemelli, R.M.5
Sinton, C.M.6
Sugiyama, F.7
Yagami, K.8
Goto, K.9
Yanagisawa, M.10
Sakurai, T.11
-
22
-
-
0035847577
-
The suprachiasmatic nucleus projects to posterior hypothalamic arousal systems
-
Abrahamson, E.E.; Leak, R.K.; Moore, R.Y. The suprachiasmatic nucleus projects to posterior hypothalamic arousal systems. Neuroreport, 2001, 12, 435-440.
-
(2001)
Neuroreport
, vol.12
, pp. 435-440
-
-
Abrahamson, E.E.1
Leak, R.K.2
Moore, R.Y.3
-
23
-
-
4243302729
-
Orexin (hypocretin) neurons contain dynorphin
-
Chou, T.C.; Lee, C.E.; Lu, J.; Elmquist, J.K.; Hara, J.; Willie, J.T.; Beuckmann, C.T.; Chemelli, R.M.; Sakurai, T.; Yanagisawa, M.; Saper, C.B.; Scammell, T.E. Orexin (hypocretin) neurons contain dynorphin. J. Neurosci., 2001, 21, RC168.
-
(2001)
J. Neurosci
, vol.21
-
-
Chou, T.C.1
Lee, C.E.2
Lu, J.3
Elmquist, J.K.4
Hara, J.5
Willie, J.T.6
Beuckmann, C.T.7
Chemelli, R.M.8
Sakurai, T.9
Yanagisawa, M.10
Saper, C.B.11
Scammell, T.E.12
-
24
-
-
0141593423
-
Hypothalamic orexin (hypocretin) neurons express vesicular glutamate transporters VGLUT1 or VGLUT2
-
Rosin, D.L.; Weston, M.C.; Sevigny, C.P.; Stornetta, R.L.; Guyenet, P.G. Hypothalamic orexin (hypocretin) neurons express vesicular glutamate transporters VGLUT1 or VGLUT2. J. Comp. Neurol., 2003, 465, 593-603.
-
(2003)
J. Comp. Neurol
, vol.465
, pp. 593-603
-
-
Rosin, D.L.1
Weston, M.C.2
Sevigny, C.P.3
Stornetta, R.L.4
Guyenet, P.G.5
-
25
-
-
75749119042
-
-
American Academy of Sleep medicine, D.C.S.C. The International Classification of Sleep Disorders: Diagnostic and Coding Manual, 2005, (American Academy of Sleep Medicine).
-
American Academy of Sleep medicine, D.C.S.C. The International Classification of Sleep Disorders: Diagnostic and Coding Manual, 2005, (American Academy of Sleep Medicine).
-
-
-
-
26
-
-
33745512663
-
The neurobiology of hypocretins (orexins), narcolepsy and related therapeutic interventions
-
Zeitzer, J.M.; Nishino, S.; Mignot, E. The neurobiology of hypocretins (orexins), narcolepsy and related therapeutic interventions. Trends Pharmacol. Sci., 2006, 27, 368-374.
-
(2006)
Trends Pharmacol. Sci
, vol.27
, pp. 368-374
-
-
Zeitzer, J.M.1
Nishino, S.2
Mignot, E.3
-
27
-
-
1842584959
-
Orexin peptides prevent cataplexy and improve wakefulness in an orexin neuron-ablated model of narcolepsy in mice
-
Mieda, M.; Willie, J.T.; Hara, J.; Sinton, C.M.; Sakurai, T.; Yanagisawa, M. Orexin peptides prevent cataplexy and improve wakefulness in an orexin neuron-ablated model of narcolepsy in mice. Proc. Natl. Acad. Sci. USA, 2004, 101, 4649-4654.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 4649-4654
-
-
Mieda, M.1
Willie, J.T.2
Hara, J.3
Sinton, C.M.4
Sakurai, T.5
Yanagisawa, M.6
-
28
-
-
1642382070
-
Effects of IV and ICV hypocretin-1 (orexin A) in hypocretin receptor-2 gene mutated narcoleptic dogs and IV hypocretin-1 replacement therapy in a hypocretin-ligand-deficient narcoleptic dog
-
Fujiki, N.; Yoshida, Y.; Ripley, B.; Mignot, E.; Nishino, S. Effects of IV and ICV hypocretin-1 (orexin A) in hypocretin receptor-2 gene mutated narcoleptic dogs and IV hypocretin-1 replacement therapy in a hypocretin-ligand-deficient narcoleptic dog. Sleep, 2003, 26, 953-959.
-
(2003)
Sleep
, vol.26
, pp. 953-959
-
-
Fujiki, N.1
Yoshida, Y.2
Ripley, B.3
Mignot, E.4
Nishino, S.5
-
29
-
-
33846979755
-
Promotion of sleep by targeting the orexin system in rats, dogs and humans
-
Brisbare-Roch, C.; Dingemanse, J.; Koberstein, R.; Hoever, P.; Aissaoui, H.; Flores, S.; Mueller, C.; Nayler, O.; van Gerven, J.; de Haas, S.L.; Hess, P.; Qiu, C.; Buchmann, S.; Scherz, M.; Weller, T.; Fischli, W.; Clozel, M.; Jenck, F. Promotion of sleep by targeting the orexin system in rats, dogs and humans. Nat. Med., 2007, 13, 150-155.
-
(2007)
Nat. Med
, vol.13
, pp. 150-155
-
-
Brisbare-Roch, C.1
Dingemanse, J.2
Koberstein, R.3
Hoever, P.4
Aissaoui, H.5
Flores, S.6
Mueller, C.7
Nayler, O.8
van Gerven, J.9
de Haas, S.L.10
Hess, P.11
Qiu, C.12
Buchmann, S.13
Scherz, M.14
Weller, T.15
Fischli, W.16
Clozel, M.17
Jenck, F.18
-
30
-
-
0029437324
-
Physiology of REM sleep, cataplexy, and sleep paralysis
-
Hishikawa, Y.; Shimizu, T. Physiology of REM sleep, cataplexy, and sleep paralysis. Adv. Neurol., 1995, 67, 245-271.
-
(1995)
Adv. Neurol
, vol.67
, pp. 245-271
-
-
Hishikawa, Y.1
Shimizu, T.2
-
31
-
-
0035576935
-
The sleep switch: Hypothalamic control of sleep and wakefulness
-
Saper, C.B.; Chou, T.C.; Scammell, T.E. The sleep switch: hypothalamic control of sleep and wakefulness. Trends Neurosci., 2001, 24, 726-731.
-
(2001)
Trends Neurosci
, vol.24
, pp. 726-731
-
-
Saper, C.B.1
Chou, T.C.2
Scammell, T.E.3
-
32
-
-
0033552658
-
Hypocretin (orexin) activation and synaptic innervation of the locus coeruleus noradrenergic system
-
Horvath, T. L.; Peyron, C.; Diano, S.; Ivanov, A.; Aston-Jones, G.; Kilduff, T.S.; van Den Pol, A.N. Hypocretin (orexin) activation and synaptic innervation of the locus coeruleus noradrenergic system. J. Comp. Neurol., 1999, 415, 145-159.
-
(1999)
J. Comp. Neurol
, vol.415
, pp. 145-159
-
-
Horvath, T.L.1
Peyron, C.2
Diano, S.3
Ivanov, A.4
Aston-Jones, G.5
Kilduff, T.S.6
van Den Pol, A.N.7
-
33
-
-
18444375874
-
Orexins activate histaminergic neurons via the orexin 2 receptor
-
Yamanaka, A.; Tsujino, N.; Funahashi, H.; Honda, K.; Guan, J.L.; Wang, Q.P.; Tominaga, M.; Goto, K.; Shioda, S.; Sakurai, T. Orexins activate histaminergic neurons via the orexin 2 receptor. Biochem. Biophys. Res. Commun., 2002, 290, 1237-1245.
-
(2002)
Biochem. Biophys. Res. Commun
, vol.290
, pp. 1237-1245
-
-
Yamanaka, A.1
Tsujino, N.2
Funahashi, H.3
Honda, K.4
Guan, J.L.5
Wang, Q.P.6
Tominaga, M.7
Goto, K.8
Shioda, S.9
Sakurai, T.10
-
34
-
-
13044249865
-
Orexin A activates locus coeruleus cell firing and increases arousal in the rat
-
Hagan, J.J.; Leslie, R.A.; Patel, S.; Evans, M.L.; Wattam, T.A.; Holmes, S.; Benham, C.D.; Taylor, S.G.; Routledge, C.; Hemmati, P.; Munton, R.P.; Ashmeade, T.E.; Shah, A.S.; Hatcher, J.P.; Hatcher, P.D.; Jones, D.N.; Smith, M.I.; Piper, D.C.; Hunter, A.J.; Porter, R.A.; Upton, N. Orexin A activates locus coeruleus cell firing and increases arousal in the rat. Proc. Natl. Acad. Sci. USA, 1999, 96, 10911-10916.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 10911-10916
-
-
Hagan, J.J.1
Leslie, R.A.2
Patel, S.3
Evans, M.L.4
Wattam, T.A.5
Holmes, S.6
Benham, C.D.7
Taylor, S.G.8
Routledge, C.9
Hemmati, P.10
Munton, R.P.11
Ashmeade, T.E.12
Shah, A.S.13
Hatcher, J.P.14
Hatcher, P.D.15
Jones, D.N.16
Smith, M.I.17
Piper, D.C.18
Hunter, A.J.19
Porter, R.A.20
Upton, N.21
more..
-
35
-
-
36248996490
-
Neural substrates of awakening probed with optogenetic control of hypocretin neurons
-
Adamantidis, A.R.; Zhang, F.; Aravanis, A.M.; Deisseroth, K.; de Lecea, L. Neural substrates of awakening probed with optogenetic control of hypocretin neurons. Nature, 2007, 450, 420-424.
-
(2007)
Nature
, vol.450
, pp. 420-424
-
-
Adamantidis, A.R.1
Zhang, F.2
Aravanis, A.M.3
Deisseroth, K.4
de Lecea, L.5
-
36
-
-
0034667702
-
Hypocretin-1 modulates rapid eye movement sleep through activation of locus coeruleus neurons
-
Bourgin, P.; Huitron-Resendiz, S.; Spier, A.D.; Fabre, V.; Morte, B.; Criado, J.R.; Sutcliffe, J.G.; Henriksen, S.J.; de Lecea, L. Hypocretin-1 modulates rapid eye movement sleep through activation of locus coeruleus neurons. J. Neurosci., 2000, 20, 7760-7765.
-
(2000)
J. Neurosci
, vol.20
, pp. 7760-7765
-
-
Bourgin, P.1
Huitron-Resendiz, S.2
Spier, A.D.3
Fabre, V.4
Morte, B.5
Criado, J.R.6
Sutcliffe, J.G.7
Henriksen, S.J.8
de Lecea, L.9
-
37
-
-
0035859825
-
Arousal effect of orexin A depends on activation of the histaminergic system
-
Huang, Z.L.; Qu, W.M.; Li, W.D.; Mochizuki, T.; Eguchi, N.; Watanabe, T.; Urade, Y.; Hayaishi, O. Arousal effect of orexin A depends on activation of the histaminergic system. Proc. Natl. Acad. Sci. USA, 2001, 98, 9965-9970.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 9965-9970
-
-
Huang, Z.L.1
Qu, W.M.2
Li, W.D.3
Mochizuki, T.4
Eguchi, N.5
Watanabe, T.6
Urade, Y.7
Hayaishi, O.8
-
38
-
-
0035980449
-
Wake-promoting and sleep-suppressing actions of hypocretin (orexin): Basal forebrain sites of action
-
Espana, R.A.; Baldo, B.A.; Kelley, A.E.; Berridge, C.W. Wake-promoting and sleep-suppressing actions of hypocretin (orexin): basal forebrain sites of action. Neuroscience, 2001, 106, 699-715.
-
(2001)
Neuroscience
, vol.106
, pp. 699-715
-
-
Espana, R.A.1
Baldo, B.A.2
Kelley, A.E.3
Berridge, C.W.4
-
39
-
-
0035906548
-
Effects on sleep and wakefulness of the injection of hypocretin-1 (orexin-A) into the laterodorsal tegmental nucleus of the cat
-
Xi, M.C.; Morales, F.R.; Chase, M.H. Effects on sleep and wakefulness of the injection of hypocretin-1 (orexin-A) into the laterodorsal tegmental nucleus of the cat. Brain Res., 2001, 901, 259-264.
-
(2001)
Brain Res
, vol.901
, pp. 259-264
-
-
Xi, M.C.1
Morales, F.R.2
Chase, M.H.3
-
40
-
-
0034626857
-
Effects of lateral preoptic area application of orexin-A on sleep-wakefulness
-
Methippara, M.M.; Alam, M.N.; Szymusiak, R.; McGinty, D. Effects of lateral preoptic area application of orexin-A on sleep-wakefulness. Neuroreport, 2000, 11, 3423-3426.
-
(2000)
Neuroreport
, vol.11
, pp. 3423-3426
-
-
Methippara, M.M.1
Alam, M.N.2
Szymusiak, R.3
McGinty, D.4
-
41
-
-
0037095837
-
Hypocretin (orexin) enhances neuron activity and cell synchrony in developing mouse GFP-expressing locus coeruleus
-
van den Pol, A.N.; Ghosh, P.K.; Liu, R.J.; Li, Y.; Aghajanian, G.K.; Gao, X.B. Hypocretin (orexin) enhances neuron activity and cell synchrony in developing mouse GFP-expressing locus coeruleus. J. Physiol., 2002, 541, 169-185.
-
(2002)
J. Physiol
, vol.541
, pp. 169-185
-
-
van den Pol, A.N.1
Ghosh, P.K.2
Liu, R.J.3
Li, Y.4
Aghajanian, G.K.5
Gao, X.B.6
-
42
-
-
0035134269
-
Orexin A excites serotonergic neurons in the dorsal raphe nucleus of the rat
-
Brown, R.E.; Sergeeva, O.; Eriksson, K.S.; Haas, H.L. Orexin A excites serotonergic neurons in the dorsal raphe nucleus of the rat. Neuropharmacology, 2001, 40, 457-459.
-
(2001)
Neuropharmacology
, vol.40
, pp. 457-459
-
-
Brown, R.E.1
Sergeeva, O.2
Eriksson, K.S.3
Haas, H.L.4
-
43
-
-
0036848635
-
Hypocretins (orexins) regulate serotonin neurons in the dorsal raphe nucleus by excitatory direct and inhibitory indirect actions
-
Liu, R.J.; van den Pol, A.N.; Aghajanian, G.K. Hypocretins (orexins) regulate serotonin neurons in the dorsal raphe nucleus by excitatory direct and inhibitory indirect actions. J. Neurosci., 2002, 22, 9453-9464.
-
(2002)
J. Neurosci
, vol.22
, pp. 9453-9464
-
-
Liu, R.J.1
van den Pol, A.N.2
Aghajanian, G.K.3
-
44
-
-
0035783667
-
Orexins (hypocretins) directly excite tuberomammillary neurons
-
Bayer, L.; Eggermann, E.; Serafin, M.; Saint-Mleux, B.; Machard, D.; Jones, B.; Muhlethaler, M. Orexins (hypocretins) directly excite tuberomammillary neurons. Eur. J. Neurosci., 2001, 14, 1571-1575.
-
(2001)
Eur. J. Neurosci
, vol.14
, pp. 1571-1575
-
-
Bayer, L.1
Eggermann, E.2
Serafin, M.3
Saint-Mleux, B.4
Machard, D.5
Jones, B.6
Muhlethaler, M.7
-
45
-
-
0035576310
-
Orexin/hypocretin excites the histaminergic neurons of the tuberomammillary nucleus
-
Eriksson, K.S.; Sergeeva, O.; Brown, R.E.; Haas, H.L. Orexin/hypocretin excites the histaminergic neurons of the tuberomammillary nucleus. J. Neurosci., 2001, 21, 9273-9279.
-
(2001)
J. Neurosci
, vol.21
, pp. 9273-9279
-
-
Eriksson, K.S.1
Sergeeva, O.2
Brown, R.E.3
Haas, H.L.4
-
46
-
-
0035842557
-
Orexins/hypocretins excite basal forebrain cholinergic neurones
-
Eggermann, E.; Serafin, M.; Bayer, L.; Machard, D.; Saint-Mleux, B.; Jones, B.E.; Muhlethaler, M. Orexins/hypocretins excite basal forebrain cholinergic neurones. Neuroscience, 2001, 108, 177-181.
-
(2001)
Neuroscience
, vol.108
, pp. 177-181
-
-
Eggermann, E.1
Serafin, M.2
Bayer, L.3
Machard, D.4
Saint-Mleux, B.5
Jones, B.E.6
Muhlethaler, M.7
-
47
-
-
0036546690
-
Direct and indirect excitation of laterodorsal tegmental neurons by Hypocretin/Orexin peptides: Implications for wakefulness and narcolepsy
-
Burlet, S.; Tyler, C.J.; Leonard, C.S. Direct and indirect excitation of laterodorsal tegmental neurons by Hypocretin/Orexin peptides: implications for wakefulness and narcolepsy. J. Neurosci., 2002, 22, 2862-2872.
-
(2002)
J. Neurosci
, vol.22
, pp. 2862-2872
-
-
Burlet, S.1
Tyler, C.J.2
Leonard, C.S.3
-
48
-
-
27844592708
-
Orexinergic projections to the cat midbrain mediate alternation of emotional behavioural states from locomotion to cataplexy
-
Takakusaki, K.; Takahashi, K.; Saitoh, K.; Harada, H.; Okumura, T.; Kayama, Y.; Koyama, Y. Orexinergic projections to the cat midbrain mediate alternation of emotional behavioural states from locomotion to cataplexy. J. Physiol., 2005, 568, 1003-1020.
-
(2005)
J. Physiol
, vol.568
, pp. 1003-1020
-
-
Takakusaki, K.1
Takahashi, K.2
Saitoh, K.3
Harada, H.4
Okumura, T.5
Kayama, Y.6
Koyama, Y.7
-
49
-
-
20244374121
-
Input of orexin/hypocretin neurons revealed by a genetically encoded tracer in mice
-
Sakurai, T.; Nagata, R.; Yamanaka, A.; Kawamura, H.; Tsujino, N.; Muraki, Y.; Kageyama, H.; Kunita, S.; Takahashi, S.; Goto, K.; Koyama, Y.; Shioda, S.; Yanagisawa, M. Input of orexin/hypocretin neurons revealed by a genetically encoded tracer in mice. Neuron, 2005, 46, 297-308.
-
(2005)
Neuron
, vol.46
, pp. 297-308
-
-
Sakurai, T.1
Nagata, R.2
Yamanaka, A.3
Kawamura, H.4
Tsujino, N.5
Muraki, Y.6
Kageyama, H.7
Kunita, S.8
Takahashi, S.9
Goto, K.10
Koyama, Y.11
Shioda, S.12
Yanagisawa, M.13
-
50
-
-
30144433306
-
Afferents to the orexin neurons of the rat brain
-
Yoshida, K.; McCormack, S.; Espana, R.A.; Crocker, A.; Scammell, T.E. Afferents to the orexin neurons of the rat brain. J. Comp. Neurol., 2006, 494, 845-861.
-
(2006)
J. Comp. Neurol
, vol.494
, pp. 845-861
-
-
Yoshida, K.1
McCormack, S.2
Espana, R.A.3
Crocker, A.4
Scammell, T.E.5
-
51
-
-
0037137682
-
Hypocretin/Orexin excites hypocretin neurons via a local glutamate neuron-A potential mechanism for orchestrating the hypothalamic arousal system
-
Li, Y.; Gao, X.B.; Sakurai, T.; van den Pol, A.N. Hypocretin/Orexin excites hypocretin neurons via a local glutamate neuron-A potential mechanism for orchestrating the hypothalamic arousal system. Neuron, 2002, 36, 1169-1181.
-
(2002)
Neuron
, vol.36
, pp. 1169-1181
-
-
Li, Y.1
Gao, X.B.2
Sakurai, T.3
van den Pol, A.N.4
-
52
-
-
0038521277
-
Hypothalamic orexin neurons regulate arousal according to energy balance in mice
-
Yamanaka, A.; Beuckmann, C.T.; Willie, J.T.; Hara, J.; Tsujino, N.; Mieda, M.; Tominaga, M.; Yagami, K.; Sugiyama, F.; Goto, K.; Yanagisawa, M.; Sakurai, T. Hypothalamic orexin neurons regulate arousal according to energy balance in mice. Neuron, 2003, 38, 701-713.
-
(2003)
Neuron
, vol.38
, pp. 701-713
-
-
Yamanaka, A.1
Beuckmann, C.T.2
Willie, J.T.3
Hara, J.4
Tsujino, N.5
Mieda, M.6
Tominaga, M.7
Yagami, K.8
Sugiyama, F.9
Goto, K.10
Yanagisawa, M.11
Sakurai, T.12
-
53
-
-
33745755632
-
GABA(B) receptor-mediated modulation of hypocretin/orexin neurones in mouse hypothalamus
-
Xie, X.; Crowder, T.L.; Yamanaka, A.; Morairty, S.R.; Lewinter, R.D.; Sakurai, T.; Kilduff, T.S. GABA(B) receptor-mediated modulation of hypocretin/orexin neurones in mouse hypothalamus. J. Physiol., 2006, 574, 399-414.
-
(2006)
J. Physiol
, vol.574
, pp. 399-414
-
-
Xie, X.1
Crowder, T.L.2
Yamanaka, A.3
Morairty, S.R.4
Lewinter, R.D.5
Sakurai, T.6
Kilduff, T.S.7
-
54
-
-
0037470734
-
Regulation of orexin neurons by the monoaminergic and cholinergic systems
-
Yamanaka, A.; Muraki, Y.; Tsujino, N.; Goto, K.; Sakurai, T. Regulation of orexin neurons by the monoaminergic and cholinergic systems. Biochem. Biophys. Res. Commun., 2003, 303, 120-129.
-
(2003)
Biochem. Biophys. Res. Commun
, vol.303
, pp. 120-129
-
-
Yamanaka, A.1
Muraki, Y.2
Tsujino, N.3
Goto, K.4
Sakurai, T.5
-
55
-
-
4143131140
-
Serotonergic regulation of the orexin/hypocretin neurons through the 5-HT1A receptor
-
Muraki, Y.; Yamanaka, A.; Tsujino, N.; Kilduff, T.S.; Goto, K.; Sakurai, T. Serotonergic regulation of the orexin/hypocretin neurons through the 5-HT1A receptor. J. Neurosci., 2004, 24, 7159-7166.
-
(2004)
J. Neurosci
, vol.24
, pp. 7159-7166
-
-
Muraki, Y.1
Yamanaka, A.2
Tsujino, N.3
Kilduff, T.S.4
Goto, K.5
Sakurai, T.6
-
56
-
-
33745754494
-
Orexin neurons are directly and indirectly regulated by catecholamines in a complex manner
-
Yamanaka, A.; Muraki, Y.; Ichiki, K.; Tsujino, N.; Kilduff, T.S.; Goto, K.; Sakurai, T. Orexin neurons are directly and indirectly regulated by catecholamines in a complex manner. J. Neurophysiol., 2006, 96, 284-298.
-
(2006)
J. Neurophysiol
, vol.96
, pp. 284-298
-
-
Yamanaka, A.1
Muraki, Y.2
Ichiki, K.3
Tsujino, N.4
Kilduff, T.S.5
Goto, K.6
Sakurai, T.7
-
57
-
-
17644392788
-
The wake-promoting hypocretin/orexin neurons change their response to noradrenaline after sleep deprivation
-
Grivel, J.; Cvetkovic, V.; Bayer, L.; Machard, D.; Tobler, I.; Muhlethaler, M.; Serafin, M. The wake-promoting hypocretin/orexin neurons change their response to noradrenaline after sleep deprivation. J. Neurosci., 2005, 25, 4127-4130.
-
(2005)
J. Neurosci
, vol.25
, pp. 4127-4130
-
-
Grivel, J.1
Cvetkovic, V.2
Bayer, L.3
Machard, D.4
Tobler, I.5
Muhlethaler, M.6
Serafin, M.7
-
58
-
-
63149122905
-
Selective loss of GABAB receptors in orexin-producing neurons results in disrupted sleep/wakefulness architecture
-
Matsuki, T.; Nomiyama, M.; Takahira, H.; Hirashima, N.; Kilduff, T.S.; Kunita, S.; Takahashi, S.; Yagami, K.; Bettler, B.; Yanagisawa, M.; Sakurai, T. Selective loss of GABAB receptors in orexin-producing neurons results in disrupted sleep/wakefulness architecture. Proc. Natl. Acad. Sci. USA, 2009, 106(11), 4459-64.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, Issue.11
, pp. 4459-4464
-
-
Matsuki, T.1
Nomiyama, M.2
Takahira, H.3
Hirashima, N.4
Kilduff, T.S.5
Kunita, S.6
Takahashi, S.7
Yagami, K.8
Bettler, B.9
Yanagisawa, M.10
Sakurai, T.11
-
59
-
-
17844393711
-
Input organization and plasticity of hypocretin neurons: Possible clues to obesity's association with insomnia
-
Horvath, T.L.; Gao, X.B. Input organization and plasticity of hypocretin neurons: possible clues to obesity's association with insomnia. Cell Metab., 2005, 1, 279-286.
-
(2005)
Cell Metab
, vol.1
, pp. 279-286
-
-
Horvath, T.L.1
Gao, X.B.2
-
60
-
-
36849075426
-
Prolonged wakefulness induces experience-dependent synaptic plasticity in mouse hypocretin/orexin neurons
-
Rao, Y.; Liu, Z.W.; Borok, E.; Rabenstein, R.L.; Shanabrough, M.; Lu, M.; Picciotto, M.R.; Horvath, T.L.; Gao, X.B. Prolonged wakefulness induces experience-dependent synaptic plasticity in mouse hypocretin/orexin neurons. J. Clin. Invest., 2007, 117, 4022-4033.
-
(2007)
J. Clin. Invest
, vol.117
, pp. 4022-4033
-
-
Rao, Y.1
Liu, Z.W.2
Borok, E.3
Rabenstein, R.L.4
Shanabrough, M.5
Lu, M.6
Picciotto, M.R.7
Horvath, T.L.8
Gao, X.B.9
-
61
-
-
0035282983
-
Fos expression in orexin neurons varies with behavioral state
-
Estabrooke, I.V.; McCarthy, M.T.; Ko, E.; Chou, T.C.; Chemelli, R.M.; Yanagisawa, M.; Saper, C.B.; Scammell, T.E. Fos expression in orexin neurons varies with behavioral state. J. Neurosci., 2001, 21, 1656-1662.
-
(2001)
J. Neurosci
, vol.21
, pp. 1656-1662
-
-
Estabrooke, I.V.1
McCarthy, M.T.2
Ko, E.3
Chou, T.C.4
Chemelli, R.M.5
Yanagisawa, M.6
Saper, C.B.7
Scammell, T.E.8
-
62
-
-
0035783672
-
Fluctuation of extracellular hypocretin-1 (orexin A) levels in the rat in relation to the light-dark cycle and sleep-wake activities
-
Yoshida, Y.; Fujiki, N.; Nakajima, T.; Ripley, B.; Matsumura, H.; Yoneda, H.; Mignot, E.; Nishino, S. Fluctuation of extracellular hypocretin-1 (orexin A) levels in the rat in relation to the light-dark cycle and sleep-wake activities. Eur. J. Neurosci., 2001, 14, 1075-1081.
-
(2001)
Eur. J. Neurosci
, vol.14
, pp. 1075-1081
-
-
Yoshida, Y.1
Fujiki, N.2
Nakajima, T.3
Ripley, B.4
Matsumura, H.5
Yoneda, H.6
Mignot, E.7
Nishino, S.8
-
63
-
-
19544376694
-
Behavioral correlates of activity in identified hypocretin/orexin neurons
-
Mileykovskiy, B.Y.; Kiyashchenko, L.I.; Siegel, J.M. Behavioral correlates of activity in identified hypocretin/orexin neurons. Neuron, 2005, 46, 787-798.
-
(2005)
Neuron
, vol.46
, pp. 787-798
-
-
Mileykovskiy, B.Y.1
Kiyashchenko, L.I.2
Siegel, J.M.3
-
64
-
-
22244443005
-
Discharge of identified orexin/hypocretin neurons across the sleep-waking cycle
-
Lee, M.G.; Hassani, O.K.; Jones, B.E. Discharge of identified orexin/hypocretin neurons across the sleep-waking cycle. J. Neurosci., 2005, 25, 6716-6720.
-
(2005)
J. Neurosci
, vol.25
, pp. 6716-6720
-
-
Lee, M.G.1
Hassani, O.K.2
Jones, B.E.3
-
65
-
-
43049176663
-
Neuronal activity of orexin and non-orexin waking-active neurons during wake-sleep states in the mouse
-
Takahashi, K.; Lin, J.S.; Sakai, K. Neuronal activity of orexin and non-orexin waking-active neurons during wake-sleep states in the mouse. Neuroscience, 2008, 153, 860-870.
-
(2008)
Neuroscience
, vol.153
, pp. 860-870
-
-
Takahashi, K.1
Lin, J.S.2
Sakai, K.3
-
66
-
-
33846421065
-
Adenosine inhibits activity of hypocretin/orexin neurons by the A1 receptor in the lateral hypothalamus: A possible sleep-promoting effect
-
Liu, Z.W.; Gao, X.B. Adenosine inhibits activity of hypocretin/orexin neurons by the A1 receptor in the lateral hypothalamus: a possible sleep-promoting effect. J. Neurophysiol., 2007, 97, 837-848.
-
(2007)
J. Neurophysiol
, vol.97
, pp. 837-848
-
-
Liu, Z.W.1
Gao, X.B.2
-
67
-
-
37549069954
-
Systemic and nasal delivery of orexin-A (Hypocretin-1) reduces the effects of sleep deprivation on cognitive performance in nonhuman primates
-
Deadwyler, S.A.; Porrino, L.; Siegel, J.M.; Hampson, R.E. Systemic and nasal delivery of orexin-A (Hypocretin-1) reduces the effects of sleep deprivation on cognitive performance in nonhuman primates. J. Neurosci., 2007, 27, 14239-14247.
-
(2007)
J. Neurosci
, vol.27
, pp. 14239-14247
-
-
Deadwyler, S.A.1
Porrino, L.2
Siegel, J.M.3
Hampson, R.E.4
-
68
-
-
19444377722
-
Hypocretin and nicotine excite the same thalamocortical synapses in prefrontal cortex: Correlation with improved attention in rat
-
Lambe, E.K.; Olausson, P.; Horst, N.K.; Taylor, J.R.; Aghajanian, G.K. Hypocretin and nicotine excite the same thalamocortical synapses in prefrontal cortex: correlation with improved attention in rat. J. Neurosci., 2005, 25, 5225-5229.
-
(2005)
J. Neurosci
, vol.25
, pp. 5225-5229
-
-
Lambe, E.K.1
Olausson, P.2
Horst, N.K.3
Taylor, J.R.4
Aghajanian, G.K.5
-
69
-
-
0141638451
-
Hypocretin (orexin) induces calcium transients in single spines postsynaptic to identified thalamocortical boutons in prefrontal slice
-
Lambe, E.K.; Aghajanian, G.K. Hypocretin (orexin) induces calcium transients in single spines postsynaptic to identified thalamocortical boutons in prefrontal slice. Neuron, 2003, 40, 139-150.
-
(2003)
Neuron
, vol.40
, pp. 139-150
-
-
Lambe, E.K.1
Aghajanian, G.K.2
-
70
-
-
0032940785
-
The effect of the orexins on food intake: Comparison with neuropeptide Y, melanin-concentrating hormone and galanin
-
Edwards, C.M.; Abusnana, S.; Sunter, D.; Murphy, K.G.; Ghatei, M.A.; Bloom, S.R. The effect of the orexins on food intake: comparison with neuropeptide Y, melanin-concentrating hormone and galanin. J. Endocrinol., 1999, 160, R7-R12.
-
(1999)
J. Endocrinol
, vol.160
-
-
Edwards, C.M.1
Abusnana, S.2
Sunter, D.3
Murphy, K.G.4
Ghatei, M.A.5
Bloom, S.R.6
-
71
-
-
0032858014
-
Effects of single and chronic intracerebroventricular administration of the orexins on feeding in the rat
-
Haynes, A.C.; Jackson, B.; Overend, P.; Buckingham, R.E.; Wilson, S.; Tadayyon, M.; Arch, J.R. Effects of single and chronic intracerebroventricular administration of the orexins on feeding in the rat. Peptides, 1999, 20, 1099-1105.
-
(1999)
Peptides
, vol.20
, pp. 1099-1105
-
-
Haynes, A.C.1
Jackson, B.2
Overend, P.3
Buckingham, R.E.4
Wilson, S.5
Tadayyon, M.6
Arch, J.R.7
-
72
-
-
0033550889
-
Effect of lateral cerebroventricular injection of the appetite-stimulating neuropeptide, orexin and neuropeptide Y, on the various behavioral activities of rats
-
Ida, T.; Nakahara, K.; Katayama, T.; Murakami, N.; Nakazato, M. Effect of lateral cerebroventricular injection of the appetite-stimulating neuropeptide, orexin and neuropeptide Y, on the various behavioral activities of rats. Brain Res., 1999, 821, 526-529.
-
(1999)
Brain Res
, vol.821
, pp. 526-529
-
-
Ida, T.1
Nakahara, K.2
Katayama, T.3
Murakami, N.4
Nakazato, M.5
-
73
-
-
0032729636
-
Chronic intracerebroventricular administration of orexin-A to rats increases food intake in daytime, but has no effect on body weight
-
Yamanaka, A.; Sakurai, T.; Katsumoto, T.; Yanagisawa, M.; Goto, K. Chronic intracerebroventricular administration of orexin-A to rats increases food intake in daytime, but has no effect on body weight. Brain Res., 1999, 849, 248-252.
-
(1999)
Brain Res
, vol.849
, pp. 248-252
-
-
Yamanaka, A.1
Sakurai, T.2
Katsumoto, T.3
Yanagisawa, M.4
Goto, K.5
-
74
-
-
0034704445
-
A selective orexin-1 receptor antagonist reduces food consumption in male and female rats
-
Haynes, A.C.; Jackson, B.; Chapman, H.; Tadayyon, M.; Johns, A.; Porter, R.A.; Arch, J.R. A selective orexin-1 receptor antagonist reduces food consumption in male and female rats. Regul. Pept., 2000, 96, 45-51.
-
(2000)
Regul. Pept
, vol.96
, pp. 45-51
-
-
Haynes, A.C.1
Jackson, B.2
Chapman, H.3
Tadayyon, M.4
Johns, A.5
Porter, R.A.6
Arch, J.R.7
-
75
-
-
0034684981
-
Inhibition of food intake by central injection of anti-orexin antibody in fasted rats
-
Yamada, H.; Okumura, T.; Motomura, W.; Kobayashi, Y.; Kohgo, Y. Inhibition of food intake by central injection of anti-orexin antibody in fasted rats. Biochem. Biophys. Res. Commun., 2000, 267, 527-531.
-
(2000)
Biochem. Biophys. Res. Commun
, vol.267
, pp. 527-531
-
-
Yamada, H.1
Okumura, T.2
Motomura, W.3
Kobayashi, Y.4
Kohgo, Y.5
-
76
-
-
0037086814
-
Anorectic, thermogenic and anti-obesity activity of a selective orexin-1 receptor antagonist in ob/ob mice
-
Haynes, A.C.; Chapman, H.; Taylor, C.; Moore, G.B.; Cawthorne, M.A.; Tadayyon, M.; Clapham, J.C.; Arch, J.R. Anorectic, thermogenic and anti-obesity activity of a selective orexin-1 receptor antagonist in ob/ob mice. Regul. Pept., 2002, 104, 153-159.
-
(2002)
Regul. Pept
, vol.104
, pp. 153-159
-
-
Haynes, A.C.1
Chapman, H.2
Taylor, C.3
Moore, G.B.4
Cawthorne, M.A.5
Tadayyon, M.6
Clapham, J.C.7
Arch, J.R.8
-
77
-
-
0030025684
-
Spontaneous food choice in narcolepsy
-
Lammers, G.J.; Pijl, H.; Iestra, J.; Langius, J.A.; Buunk, G.; Meinders, A.E. Spontaneous food choice in narcolepsy. Sleep, 1996, 19, 75-76.
-
(1996)
Sleep
, vol.19
, pp. 75-76
-
-
Lammers, G.J.1
Pijl, H.2
Iestra, J.3
Langius, J.A.4
Buunk, G.5
Meinders, A.E.6
-
78
-
-
0034621042
-
Increased body-mass index in patients with narcolepsy
-
Schuld, A.; Hebebrand, J.; Geller, F.; Pollmacher, T. Increased body-mass index in patients with narcolepsy. Lancet, 2000, 355, 1274-1275.
-
(2000)
Lancet
, vol.355
, pp. 1274-1275
-
-
Schuld, A.1
Hebebrand, J.2
Geller, F.3
Pollmacher, T.4
-
79
-
-
18144370824
-
Difference in obesity phenotype between orexin-knockout mice and orexin neuron-deficient mice with same genetic background and environmental conditions
-
Hara, J.; Yanagisawa, M.; Sakurai, T. Difference in obesity phenotype between orexin-knockout mice and orexin neuron-deficient mice with same genetic background and environmental conditions. Neurosci. Lett., 2005, 380, 239-242.
-
(2005)
Neurosci. Lett
, vol.380
, pp. 239-242
-
-
Hara, J.1
Yanagisawa, M.2
Sakurai, T.3
-
80
-
-
0032576536
-
Hypocretin/orexin- and melanin-concentrating hormone-expressing cells form distinct populations in the rodent lateral hypothalamus: Relationship to the neuropeptide Y and agouti gene-related protein systems
-
Broberger, C.; De Lecea, L.; Sutcliffe, J.G.; Hokfelt, T. Hypocretin/orexin- and melanin-concentrating hormone-expressing cells form distinct populations in the rodent lateral hypothalamus: relationship to the neuropeptide Y and agouti gene-related protein systems. J. Comp. Neurol., 1998, 402, 460-474.
-
(1998)
J. Comp. Neurol
, vol.402
, pp. 460-474
-
-
Broberger, C.1
De Lecea, L.2
Sutcliffe, J.G.3
Hokfelt, T.4
-
81
-
-
0032576592
-
Chemically defined projections linking the mediobasal hypothalamus and the lateral hypothalamic area
-
Elias, C.F.; Saper, C.B.; Maratos-Flier, E.; Tritos, N.A.; Lee, C.; Kelly, J.; Tatro, J.B.; Hoffman, G.E.; Ollmann, M.M.; Barsh, G.S.; Sakurai, T.; Yanagisawa, M.; Elmquist, J.K. Chemically defined projections linking the mediobasal hypothalamus and the lateral hypothalamic area. J. Comp. Neurol., 1998, 402, 442-459.
-
(1998)
J. Comp. Neurol
, vol.402
, pp. 442-459
-
-
Elias, C.F.1
Saper, C.B.2
Maratos-Flier, E.3
Tritos, N.A.4
Lee, C.5
Kelly, J.6
Tatro, J.B.7
Hoffman, G.E.8
Ollmann, M.M.9
Barsh, G.S.10
Sakurai, T.11
Yanagisawa, M.12
Elmquist, J.K.13
-
82
-
-
0033081871
-
Synaptic interaction between hypocretin (orexin) and neuropeptide Y cells in the rodent and primate hypothalamus: A novel circuit implicated in metabolic and endocrine regulations
-
Horvath, T.L.; Diano, S.; van den Pol, A.N. Synaptic interaction between hypocretin (orexin) and neuropeptide Y cells in the rodent and primate hypothalamus: a novel circuit implicated in metabolic and endocrine regulations. J. Neurosci., 1999, 19, 1072-1087.
-
(1999)
J. Neurosci
, vol.19
, pp. 1072-1087
-
-
Horvath, T.L.1
Diano, S.2
van den Pol, A.N.3
-
83
-
-
0034708393
-
Orexin-induced food intake involves neuropeptide Y pathway
-
Yamanaka, A.; Kunii, K.; Nambu, T.; Tsujino, N.; Sakai, A.; Matsuzaki, I.; Miwa, Y.; Goto, K.; Sakurai, T. Orexin-induced food intake involves neuropeptide Y pathway. Brain Res., 2000, 859, 404-409.
-
(2000)
Brain Res
, vol.859
, pp. 404-409
-
-
Yamanaka, A.1
Kunii, K.2
Nambu, T.3
Tsujino, N.4
Sakai, A.5
Matsuzaki, I.6
Miwa, Y.7
Goto, K.8
Sakurai, T.9
-
84
-
-
12144288387
-
2+ signaling in a reciprocal manner to leptin: Orexigenic neuronal pathways in the mediobasal hypothalamus
-
2+ signaling in a reciprocal manner to leptin: orexigenic neuronal pathways in the mediobasal hypothalamus. Eur. J. Neurosci., 2004, 19, 1524-1534.
-
(2004)
Eur. J. Neurosci
, vol.19
, pp. 1524-1534
-
-
Muroya, S.1
Funahashi, H.2
Yamanaka, A.3
Kohno, D.4
Uramura, K.5
Nambu, T.6
Shibahara, M.7
Kuramochi, M.8
Takigawa, M.9
Yanagisawa, M.10
Sakurai, T.11
Shioda, S.12
Yada, T.13
-
85
-
-
21544471830
-
Orexin A in the nucleus accumbens stimulates feeding and locomotor activity
-
Thorpe, A.J.; Kotz, C.M. Orexin A in the nucleus accumbens stimulates feeding and locomotor activity. Brain Res., 2005, 1050, 156-162.
-
(2005)
Brain Res
, vol.1050
, pp. 156-162
-
-
Thorpe, A.J.1
Kotz, C.M.2
-
86
-
-
0842330416
-
Activation of a subpopulation of orexin/hypocretin-containing hypothalamic neurons by GABAA receptor-mediated inhibition of the nucleus accumbens shell, but not by exposure to a novel environment
-
Baldo, B.A.; Gual-Bonilla, L.; Sijapati, K.; Daniel, R.A.; Landry, C.F.; Kelley, A.E. Activation of a subpopulation of orexin/hypocretin-containing hypothalamic neurons by GABAA receptor-mediated inhibition of the nucleus accumbens shell, but not by exposure to a novel environment. Eur. J. Neurosci., 2004, 19, 376-386.
-
(2004)
Eur. J. Neurosci
, vol.19
, pp. 376-386
-
-
Baldo, B.A.1
Gual-Bonilla, L.2
Sijapati, K.3
Daniel, R.A.4
Landry, C.F.5
Kelley, A.E.6
-
87
-
-
0032545511
-
Independent feeding and metabolic actions of orexins in mice
-
Lubkin, M.; Stricker-Krongrad, A. Independent feeding and metabolic actions of orexins in mice. Biochem. Biophys. Res. Commun., 1998, 253, 241-245.
-
(1998)
Biochem. Biophys. Res. Commun
, vol.253
, pp. 241-245
-
-
Lubkin, M.1
Stricker-Krongrad, A.2
-
88
-
-
0035936764
-
Obesity and the regulation of energy balance
-
Spiegelman, B.M.; Flier, J.S. Obesity and the regulation of energy balance. Cell, 2001, 104, 531-543.
-
(2001)
Cell
, vol.104
, pp. 531-543
-
-
Spiegelman, B.M.1
Flier, J.S.2
-
89
-
-
0033398188
-
Sympathetic and cardiovascular actions of orexins in conscious rats
-
Shirasaka, T.; Nakazato, M.; Matsukura, S.; Takasaki, M.; Kannan, H. Sympathetic and cardiovascular actions of orexins in conscious rats. Am. J. Physiol., 1999, 277, R1780-R1785.
-
(1999)
Am. J. Physiol
, vol.277
-
-
Shirasaka, T.1
Nakazato, M.2
Matsukura, S.3
Takasaki, M.4
Kannan, H.5
-
90
-
-
0041629653
-
Attenuated defense response and low basal blood pressure in orexin knockout mice
-
Kayaba, Y.; Nakamura, A.; Kasuya, Y.; Ohuchi, T.; Yanagisawa, M.; Komuro, I.; Fukuda, Y.; Kuwaki, T. Attenuated defense response and low basal blood pressure in orexin knockout mice. Am. J. Physiol. Regul. Integr. Comp. Physiol., 2003, 285, R581-R593.
-
(2003)
Am. J. Physiol. Regul. Integr. Comp. Physiol
, vol.285
-
-
Kayaba, Y.1
Nakamura, A.2
Kasuya, Y.3
Ohuchi, T.4
Yanagisawa, M.5
Komuro, I.6
Fukuda, Y.7
Kuwaki, T.8
-
91
-
-
33744801936
-
Orexin neuron-mediated skeletal muscle vasodilation and shift of baroreflex during defense response in mice
-
Zhang, W.; Sakurai, T.; Fukuda, Y.; Kuwaki, T. Orexin neuron-mediated skeletal muscle vasodilation and shift of baroreflex during defense response in mice. Am. J. Physiol. Regul. Integr. Comp. Physiol., 2006, 290, R1654-R1663.
-
(2006)
Am. J. Physiol. Regul. Integr. Comp. Physiol
, vol.290
-
-
Zhang, W.1
Sakurai, T.2
Fukuda, Y.3
Kuwaki, T.4
-
92
-
-
0033515711
-
Neurons containing orexin in the lateral hypothalamic area of the adult rat brain are activated by insulin-induced acute hypoglycemia
-
Moriguchi, T.; Sakurai, T.; Nambu, T.; Yanagisawa, M.; Goto, K. Neurons containing orexin in the lateral hypothalamic area of the adult rat brain are activated by insulin-induced acute hypoglycemia. Neurosci. Lett., 1999, 264, 101-104.
-
(1999)
Neurosci. Lett
, vol.264
, pp. 101-104
-
-
Moriguchi, T.1
Sakurai, T.2
Nambu, T.3
Yanagisawa, M.4
Goto, K.5
-
93
-
-
14644396121
-
Physiological changes in glucose differentially modulate the excitability of hypothalamic melanin-concentrating hormone and orexin neurons in situ
-
Burdakov, D.; Gerasimenko, O.; Verkhratsky, A. Physiological changes in glucose differentially modulate the excitability of hypothalamic melanin-concentrating hormone and orexin neurons in situ. J. Neurosci., 2005, 25, 2429-2433.
-
(2005)
J. Neurosci
, vol.25
, pp. 2429-2433
-
-
Burdakov, D.1
Gerasimenko, O.2
Verkhratsky, A.3
-
94
-
-
33646914929
-
Tandem-pore K+ channels mediate inhibition of orexin neurons by glucose
-
Burdakov, D.; Jensen, L.T.; Alexopoulos, H.; Williams, R.H.; Fearon, I.M.; O'Kelly, I.; Gerasimenko, O.; Fugger, L.; Verkhratsky, A. Tandem-pore K+ channels mediate inhibition of orexin neurons by glucose. Neuron, 2006, 50, 711-722.
-
(2006)
Neuron
, vol.50
, pp. 711-722
-
-
Burdakov, D.1
Jensen, L.T.2
Alexopoulos, H.3
Williams, R.H.4
Fearon, I.M.5
O'Kelly, I.6
Gerasimenko, O.7
Fugger, L.8
Verkhratsky, A.9
-
95
-
-
0343742214
-
Effect of prolonged fasting and subsequent refeeding on free-running rhythms of temperature and locomotor activity in rats
-
Challet, E.; Pevet, P.; Malan, A. Effect of prolonged fasting and subsequent refeeding on free-running rhythms of temperature and locomotor activity in rats. Behav. Brain Res., 1997, 84, 275-284.
-
(1997)
Behav. Brain Res
, vol.84
, pp. 275-284
-
-
Challet, E.1
Pevet, P.2
Malan, A.3
-
96
-
-
0025120247
-
Effects of 24-hr fasting on methamphetamine- and apomorphine-induced locomotor activities, and on monoamine metabolism in mouse corpus striatum and nucleus accumbens
-
Itoh, T.; Murai, S.; Nagahama, H.; Miyate, H.; Abe, E.; Fujiwara, H.; Saito, Y. Effects of 24-hr fasting on methamphetamine- and apomorphine-induced locomotor activities, and on monoamine metabolism in mouse corpus striatum and nucleus accumbens. Pharmacol. Biochem. Behav., 1990, 35, 391-396.
-
(1990)
Pharmacol. Biochem. Behav
, vol.35
, pp. 391-396
-
-
Itoh, T.1
Murai, S.2
Nagahama, H.3
Miyate, H.4
Abe, E.5
Fujiwara, H.6
Saito, Y.7
-
97
-
-
9244251539
-
Orexin neurons function in an efferent pathway of a food-entrainable circadian oscillator in eliciting food-anticipatory activity and wakefulness
-
Mieda, M.; Williams, S.C.; Sinton, C.M.; Richardson, J.A.; Sakurai, T.; Yanagisawa, M. Orexin neurons function in an efferent pathway of a food-entrainable circadian oscillator in eliciting food-anticipatory activity and wakefulness. J. Neurosci., 2004, 24, 10493-10501.
-
(2004)
J. Neurosci
, vol.24
, pp. 10493-10501
-
-
Mieda, M.1
Williams, S.C.2
Sinton, C.M.3
Richardson, J.A.4
Sakurai, T.5
Yanagisawa, M.6
-
98
-
-
10844253886
-
Reduced food anticipatory activity in genetically orexin (hypocretin) neuron-ablated mice
-
Akiyama, M.; Yuasa, T.; Hayasaka, N.; Horikawa, K.; Sakurai, T.; Shibata, S. Reduced food anticipatory activity in genetically orexin (hypocretin) neuron-ablated mice. Eur. J. Neurosci., 2004, 20, 3054-3062.
-
(2004)
Eur. J. Neurosci
, vol.20
, pp. 3054-3062
-
-
Akiyama, M.1
Yuasa, T.2
Hayasaka, N.3
Horikawa, K.4
Sakurai, T.5
Shibata, S.6
-
99
-
-
0033581348
-
Orexins/hypocretins regulate drinking behaviour
-
Kunii, K.; Yamanaka, A.; Nambu, T.; Matsuzaki, I.; Goto, K.; Sakurai, T. Orexins/hypocretins regulate drinking behaviour. Brain Res., 1999, 842, 256-261.
-
(1999)
Brain Res
, vol.842
, pp. 256-261
-
-
Kunii, K.1
Yamanaka, A.2
Nambu, T.3
Matsuzaki, I.4
Goto, K.5
Sakurai, T.6
-
100
-
-
38149077384
-
Vasopressin increases locomotion through a V1a receptor in orexin/hypocretin neurons: Implications for water homeostasis
-
Tsunematsu, T.; Fu, L.Y.; Yamanaka, A.; Ichiki, K.; Tanoue, A.; Sakurai, T.; van den Pol, A.N. Vasopressin increases locomotion through a V1a receptor in orexin/hypocretin neurons: implications for water homeostasis. J. Neurosci., 2008, 28, 228-238.
-
(2008)
J. Neurosci
, vol.28
, pp. 228-238
-
-
Tsunematsu, T.1
Fu, L.Y.2
Yamanaka, A.3
Ichiki, K.4
Tanoue, A.5
Sakurai, T.6
van den Pol, A.N.7
-
101
-
-
23744456008
-
Cholecystokinin activates orexin/hypocretin neurons through the cholecystokinin A receptor
-
Tsujino, N.; Yamanaka, A.; Ichiki, K.; Muraki, Y.; Kilduff, T.S.; Yagami, K.; Takahashi, S.; Goto, K.; Sakurai, T. Cholecystokinin activates orexin/hypocretin neurons through the cholecystokinin A receptor. J. Neurosci., 2005, 25, 7459-7469.
-
(2005)
J. Neurosci
, vol.25
, pp. 7459-7469
-
-
Tsujino, N.1
Yamanaka, A.2
Ichiki, K.3
Muraki, Y.4
Kilduff, T.S.5
Yagami, K.6
Takahashi, S.7
Goto, K.8
Sakurai, T.9
-
102
-
-
0037052657
-
Anatomical substrates of orexin-dopamine interactions: Lateral hypothalamic projections to the ventral tegmental area
-
Fadel, J.; Deutch, A.Y. Anatomical substrates of orexin-dopamine interactions: lateral hypothalamic projections to the ventral tegmental area. Neuroscience, 2002, 111, 379-387.
-
(2002)
Neuroscience
, vol.111
, pp. 379-387
-
-
Fadel, J.1
Deutch, A.Y.2
-
103
-
-
0034604826
-
Orexin-induced hyperlocomotion and stereotypy are mediated by the dopaminergic system
-
Nakamura, T.; Uramura, K.; Nambu, T.; Yada, T.; Goto, K.; Yanagisawa, M.; Sakurai, T. Orexin-induced hyperlocomotion and stereotypy are mediated by the dopaminergic system. Brain Res., 2000, 873, 181-187.
-
(2000)
Brain Res
, vol.873
, pp. 181-187
-
-
Nakamura, T.1
Uramura, K.2
Nambu, T.3
Yada, T.4
Goto, K.5
Yanagisawa, M.6
Sakurai, T.7
-
104
-
-
0037220974
-
Excitation of ventral tegmental area dopaminergic and nondopaminergic neurons by orexins/hypocretins
-
Korotkova, T.M.; Sergeeva, O.A.; Eriksson, K.S.; Haas, H.L.; Brown, R.E. Excitation of ventral tegmental area dopaminergic and nondopaminergic neurons by orexins/hypocretins. J. Neurosci., 2003, 23, 7-11.
-
(2003)
J. Neurosci
, vol.23
, pp. 7-11
-
-
Korotkova, T.M.1
Sergeeva, O.A.2
Eriksson, K.S.3
Haas, H.L.4
Brown, R.E.5
-
105
-
-
12144254721
-
Direct and indirect inhibition by catecholamines of hypocretin/orexin neurons
-
Li, Y.; van den Pol, A.N. Direct and indirect inhibition by catecholamines of hypocretin/orexin neurons. J. Neurosci., 2005, 25, 173-183.
-
(2005)
J. Neurosci
, vol.25
, pp. 173-183
-
-
Li, Y.1
van den Pol, A.N.2
-
106
-
-
25644432796
-
A role for lateral hypothalamic orexin neurons in reward seeking
-
Harris, G.C.; Wimmer, M.; Aston-Jones, G. A role for lateral hypothalamic orexin neurons in reward seeking. Nature, 2005, 437, 556-559.
-
(2005)
Nature
, vol.437
, pp. 556-559
-
-
Harris, G.C.1
Wimmer, M.2
Aston-Jones, G.3
-
107
-
-
32344453801
-
Direct involvement of orexinergic systems in the activation of the mesolimbic dopamine pathway and related behaviors induced by morphine
-
Narita, M.; Nagumo, Y.; Hashimoto, S.; Khotib, J.; Miyatake, M.; Sakurai, T.; Yanagisawa, M.; Nakamachi, T.; Shioda, S.; Suzuki, T. Direct involvement of orexinergic systems in the activation of the mesolimbic dopamine pathway and related behaviors induced by morphine. J. Neurosci., 2006, 26, 398-405.
-
(2006)
J. Neurosci
, vol.26
, pp. 398-405
-
-
Narita, M.1
Nagumo, Y.2
Hashimoto, S.3
Khotib, J.4
Miyatake, M.5
Sakurai, T.6
Yanagisawa, M.7
Nakamachi, T.8
Shioda, S.9
Suzuki, T.10
-
108
-
-
32344446144
-
Orexin A in the VTA is critical for the induction of synaptic plasticity and behavioral sensitization to cocaine
-
Borgland, S.L.; Taha, S.A.; Sarti, F.; Fields, H.L.; Bonci, A. Orexin A in the VTA is critical for the induction of synaptic plasticity and behavioral sensitization to cocaine. Neuron, 2006, 49, 589-601.
-
(2006)
Neuron
, vol.49
, pp. 589-601
-
-
Borgland, S.L.1
Taha, S.A.2
Sarti, F.3
Fields, H.L.4
Bonci, A.5
-
109
-
-
33947326579
-
A role for hypocretin (orexin) in male sexual behavior
-
Muschamp, J.W.; Dominguez, J.M.; Sato, S.M.; Shen, R.Y.; Hull, E.M. A role for hypocretin (orexin) in male sexual behavior. J. Neurosci., 2007, 27, 2837-2845.
-
(2007)
J. Neurosci
, vol.27
, pp. 2837-2845
-
-
Muschamp, J.W.1
Dominguez, J.M.2
Sato, S.M.3
Shen, R.Y.4
Hull, E.M.5
-
110
-
-
30044447392
-
Role for hypocretin in mediating stress-induced reinstatement of cocaine-seeking behavior
-
Boutrel, B.; Kenny, P.J.; Specio, S.E.; Martin-Fardon, R.; Markou, A.; Koob, G.F.; de Lecea, L. Role for hypocretin in mediating stress-induced reinstatement of cocaine-seeking behavior. Proc. Natl. Acad. Sci. USA, 2005, 102, 19168-19173.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 19168-19173
-
-
Boutrel, B.1
Kenny, P.J.2
Specio, S.E.3
Martin-Fardon, R.4
Markou, A.5
Koob, G.F.6
de Lecea, L.7
-
111
-
-
0037659189
-
Involvement of the lateral hypothalamic peptide orexin in morphine dependence and withdrawal
-
Georgescu, D.; Zachariou, V.; Barrot, M.; Mieda, M.; Willie, J.T.; Eisch, A.J.; Yanagisawa, M.; Nestler, E.J.; DiLeone, R.J. Involvement of the lateral hypothalamic peptide orexin in morphine dependence and withdrawal. J. Neurosci., 2003, 23, 3106-3111.
-
(2003)
J. Neurosci
, vol.23
, pp. 3106-3111
-
-
Georgescu, D.1
Zachariou, V.2
Barrot, M.3
Mieda, M.4
Willie, J.T.5
Eisch, A.J.6
Yanagisawa, M.7
Nestler, E.J.8
DiLeone, R.J.9
-
112
-
-
0015944779
-
On the treatment of rapid eye movement narcolepsy
-
Guilleminault, C.; Carskadon, M.; Dement, W.C. On the treatment of rapid eye movement narcolepsy. Arch. Neurol., 1974, 30, 90-93.
-
(1974)
Arch. Neurol
, vol.30
, pp. 90-93
-
-
Guilleminault, C.1
Carskadon, M.2
Dement, W.C.3
-
113
-
-
0028788998
-
Central command neurons of the sympathetic nervous system: Basis of the fight-or-flight response
-
Jansen, A.S.; Nguyen, X.V.; Karpitskiy, V.; Mettenleiter, T.C.; Loewy, A.D. Central command neurons of the sympathetic nervous system: basis of the fight-or-flight response. Science, 1995, 270, 644-646.
-
(1995)
Science
, vol.270
, pp. 644-646
-
-
Jansen, A.S.1
Nguyen, X.V.2
Karpitskiy, V.3
Mettenleiter, T.C.4
Loewy, A.D.5
-
114
-
-
0242570457
-
Orexin neurons project to diverse sympathetic outflow systems
-
Geerling, J.C.; Mettenleiter, T.C.; Loewy, A.D. Orexin neurons project to diverse sympathetic outflow systems. Neuroscience, 2003, 122, 541-550.
-
(2003)
Neuroscience
, vol.122
, pp. 541-550
-
-
Geerling, J.C.1
Mettenleiter, T.C.2
Loewy, A.D.3
-
115
-
-
0000905566
-
Centrally administered orexin/hypocretin activates HPA axis in rats
-
Kuru, M.; Ueta, Y.; Serino, R.; Nakazato, M.; Yamamoto, Y.; Shibuya, I.; Yamashita, H. Centrally administered orexin/hypocretin activates HPA axis in rats. Neuroreport, 2000, 11, 1977-1980.
-
(2000)
Neuroreport
, vol.11
, pp. 1977-1980
-
-
Kuru, M.1
Ueta, Y.2
Serino, R.3
Nakazato, M.4
Yamamoto, Y.5
Shibuya, I.6
Yamashita, H.7
-
116
-
-
1542270814
-
Centrally administered orexin-A activates corticotropin-releasing factor-containing neurons in the hypothalamic paraventricular nucleus and central amygdaloid nucleus of rats: Possible involvement of central orexins on stress-activated central CRF neurons
-
Sakamoto, F.; Yamada, S.; Ueta, Y. Centrally administered orexin-A activates corticotropin-releasing factor-containing neurons in the hypothalamic paraventricular nucleus and central amygdaloid nucleus of rats: possible involvement of central orexins on stress-activated central CRF neurons. Regul. Pept., 2004, 118, 183-191.
-
(2004)
Regul. Pept
, vol.118
, pp. 183-191
-
-
Sakamoto, F.1
Yamada, S.2
Ueta, Y.3
-
117
-
-
10644267749
-
Interaction between the corticotropin-releasing factor system and hypocretins (orexins): A novel circuit mediating stress response
-
Winsky-Sommerer, R.; Yamanaka, A.; Diano, S.; Borok, E.; Roberts, A.J.; Sakurai, T.; Kilduff, T.S.; Horvath, T.L.; de Lecea, L. Interaction between the corticotropin-releasing factor system and hypocretins (orexins): a novel circuit mediating stress response. J. Neurosci., 2004, 24, 11439-11448.
-
(2004)
J. Neurosci
, vol.24
, pp. 11439-11448
-
-
Winsky-Sommerer, R.1
Yamanaka, A.2
Diano, S.3
Borok, E.4
Roberts, A.J.5
Sakurai, T.6
Kilduff, T.S.7
Horvath, T.L.8
de Lecea, L.9
-
118
-
-
33749075175
-
Narcolepsy and the hypocretin systemwhere motion meets emotion
-
Siegel, J.M.; Boehmer, L.N. Narcolepsy and the hypocretin systemwhere motion meets emotion. Nat. Clin. Pract. Neurol., 2006, 2, 548-556.
-
(2006)
Nat. Clin. Pract. Neurol
, vol.2
, pp. 548-556
-
-
Siegel, J.M.1
Boehmer, L.N.2
-
119
-
-
0031887243
-
Investigations into the neurologic basis of narcolepsy
-
Guilleminault, C.; Heinzer, R.; Mignot, E.; Black, J. Investigations into the neurologic basis of narcolepsy. Neurology, 1998, 50, S8-S15.
-
(1998)
Neurology
, vol.50
-
-
Guilleminault, C.1
Heinzer, R.2
Mignot, E.3
Black, J.4
-
120
-
-
0029446732
-
Clinical aspects and features of cataplexy
-
Guilleminault, C.; Gelb, M. Clinical aspects and features of cataplexy. Adv. Neurol., 1995, 67, 65-77.
-
(1995)
Adv. Neurol
, vol.67
, pp. 65-77
-
-
Guilleminault, C.1
Gelb, M.2
-
121
-
-
3042554011
-
Mind versus metabolism in the control of food intake and energy balance
-
Berthoud, H.R. Mind versus metabolism in the control of food intake and energy balance. Physiol. Behav., 2004, 81, 781-793.
-
(2004)
Physiol. Behav
, vol.81
, pp. 781-793
-
-
Berthoud, H.R.1
-
122
-
-
0035925698
-
Gene expression and protein distribution of the orexin-1 receptor in the rat brain and spinal cord
-
Hervieu, G.J.; Cluderay, J.E.; Harrison, D.C.; Roberts, J.C.; Leslie, R.A. Gene expression and protein distribution of the orexin-1 receptor in the rat brain and spinal cord. Neuroscience, 2001, 103, 777-797.
-
(2001)
Neuroscience
, vol.103
, pp. 777-797
-
-
Hervieu, G.J.1
Cluderay, J.E.2
Harrison, D.C.3
Roberts, J.C.4
Leslie, R.A.5
-
123
-
-
0035061724
-
Orexin-A, an hypothalamic peptide with analgesic properties
-
Bingham, S.; Davey, P.T.; Babbs, A.J.; Irving, E.A.; Sammons, M.J.; Wyles, M.; Jeffrey, P.; Cutler, L.; Riba, I.; Johns, A.; Porter, R.A.; Upton, N.; Hunter, A.J.; Parsons, A.A. Orexin-A, an hypothalamic peptide with analgesic properties. Pain, 2001, 92, 81-90.
-
(2001)
Pain
, vol.92
, pp. 81-90
-
-
Bingham, S.1
Davey, P.T.2
Babbs, A.J.3
Irving, E.A.4
Sammons, M.J.5
Wyles, M.6
Jeffrey, P.7
Cutler, L.8
Riba, I.9
Johns, A.10
Porter, R.A.11
Upton, N.12
Hunter, A.J.13
Parsons, A.A.14
-
124
-
-
0036740492
-
Analgesic effect of intrathecally administered orexin-A in the rat formalin test and in the rat hot plate test
-
Yamamoto, T.; Nozaki-Taguchi, N.; Chiba, T. Analgesic effect of intrathecally administered orexin-A in the rat formalin test and in the rat hot plate test. Br. J. Pharmacol., 2002, 137, 170-176.
-
(2002)
Br. J. Pharmacol
, vol.137
, pp. 170-176
-
-
Yamamoto, T.1
Nozaki-Taguchi, N.2
Chiba, T.3
-
125
-
-
46749122290
-
Hypocretin/orexin and nociceptin/orphanin FQ coordinately regulate analgesia in a mouse model of stress-induced analgesia
-
Xie, X.; Wisor, J.P.; Hara, J.; Crowder, T.L.; LeWinter, R.; Khroyan, T.V.; Yamanaka, A.; Diano, S.; Horvath, T.L.; Sakurai, T.; Toll, L.; Kilduff, T.S. Hypocretin/orexin and nociceptin/orphanin FQ coordinately regulate analgesia in a mouse model of stress-induced analgesia. J. Clin. Invest., 2008, 118, 2471-2481.
-
(2008)
J. Clin. Invest
, vol.118
, pp. 2471-2481
-
-
Xie, X.1
Wisor, J.P.2
Hara, J.3
Crowder, T.L.4
LeWinter, R.5
Khroyan, T.V.6
Yamanaka, A.7
Diano, S.8
Horvath, T.L.9
Sakurai, T.10
Toll, L.11
Kilduff, T.S.12
-
126
-
-
0035821431
-
Topographic organization of suprachiasmatic nucleus projection neurons
-
Leak, R.K.; Moore, R.Y. Topographic organization of suprachiasmatic nucleus projection neurons. J. Comp. Neurol., 2001, 433, 312-334.
-
(2001)
J. Comp. Neurol
, vol.433
, pp. 312-334
-
-
Leak, R.K.1
Moore, R.Y.2
-
127
-
-
0042490526
-
A clockwork web: Circadian timing in brain and periphery, in health and disease
-
Hastings, M.H.; Reddy, A.B.; Maywood, E.S. A clockwork web: circadian timing in brain and periphery, in health and disease. Nat. Rev. Neurosci., 2003, 4, 649-661.
-
(2003)
Nat. Rev. Neurosci
, vol.4
, pp. 649-661
-
-
Hastings, M.H.1
Reddy, A.B.2
Maywood, E.S.3
-
128
-
-
0036674316
-
The "other" circadian system: Food as a Zeitgeber
-
Stephan, F.K. The "other" circadian system: food as a Zeitgeber. J. Biol. Rhythms, 2002, 17, 284-292.
-
(2002)
J. Biol. Rhythms
, vol.17
, pp. 284-292
-
-
Stephan, F.K.1
-
129
-
-
0036309936
-
Effects of orexin on the laterodorsal tegmental neurones
-
Takahashi, K.; Koyama, Y.; Kayama, Y.; Yamamoto, M. Effects of orexin on the laterodorsal tegmental neurones. Psychiatry Clin. Neurosci., 2002, 56, 335-336.
-
(2002)
Psychiatry Clin. Neurosci
, vol.56
, pp. 335-336
-
-
Takahashi, K.1
Koyama, Y.2
Kayama, Y.3
Yamamoto, M.4
-
130
-
-
0003770677
-
-
2nd ed, Appleton & Lange: Stamford, Connecticut
-
Martin, J.H. Neuroanatomy: Text and Atlas, 2nd ed.; Appleton & Lange: Stamford, Connecticut, 2001.
-
(2001)
Neuroanatomy: Text and Atlas
-
-
Martin, J.H.1
-
131
-
-
33847121297
-
The neural circuit of orexin (hypocretin): Maintaining sleep and wakefulness
-
Sakurai, T. The neural circuit of orexin (hypocretin): maintaining sleep and wakefulness. Nat. Rev. Neurosci., 2007, 8, 171-181.
-
(2007)
Nat. Rev. Neurosci
, vol.8
, pp. 171-181
-
-
Sakurai, T.1
|