Orexin-induced food intake involves neuropeptide Y pathway

Brain Research

Volumn 859, Issue 2, 2000, Pages 404-409

  Yamanaka, Akihiro ^a   Kunii, Kaiko ^a   Nambu, Tadahiro ^a   Tsujino, Natsuko ^a   Sakai, Ai ^a   Matsuzaki, Ichiyo ^a   Miwa, Yoshihiro ^a   Goto, Katsutoshi ^a   Sakurai, Takeshi ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

Author keywords

BIBO3304; Food intake; Intracerebroventricular injection; NPY; Orexin; Y1 receptor antagonist

Indexed keywords

N2 DIPHENYLACETYL N (4 UREIDOMETHYLBENZYL)ARGININAMIDE; NEUROPEPTIDE Y; NEUROPEPTIDE Y RECEPTOR ANTAGONIST; OREXIN; OREXIN A; UNCLASSIFIED DRUG;

ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FEEDING BEHAVIOR; FOOD INTAKE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ARGININE; CARRIER PROTEINS; EATING; HYPOTHALAMUS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; NEURAL PATHWAYS; NEUROPEPTIDE Y; NEUROPEPTIDES; RATS; RATS, WISTAR; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NEUROPEPTIDE; RECEPTORS, NEUROPEPTIDE Y;

EID: 0034708393     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(00)02043-6     Document Type: Article

References (25)

1. L. Aakerlund, U. Gether, J. Fuhlendorff, T.W. Schwartz, O. Thastrup, Y1 receptors for neuropeptide Y are coupled to mobilization of intracellular calcium and inhibition of adenylate cyclase, FEBS Lett. 260 (1) (1990) 73-78.
2. A.A. Balasubramaniam, Neuropeptide Y family of hormones: receptor subtypes and antagonists, Peptides 18 (3) (1997) 445-457.
3. L.L. Bernardis, L.L. Bellinger, The lateral hypothalamic area revisited: neuroanatomy, body weight regulation, neuroendocrinology and metabolism, Neurosci. Biobehav. Rev. 17 (2) (1993) 141-193.
4. C. Broberger, L. De Lecea, J.G. Sutcliffe, T. Hokfelt, Hypocretin/orexin- and melanin-concentrating hormone-expressing cells form distinct populations in the rodent lateral hypothalamus: relationship to the neuropeptide Y and agouti gene-related protein systems, J. Comp. Neurol. 402 (4) (1998) 460-474.
5. L. Criscione, P. Rigollier, C. Batzl-Hartmann, H. Rueger, A. Stricker-Krongrad, P. Wyss, L. Brunner, S. Whitebread, Y. Yamaguchi, C. Gerald, R.O. Heurich, M.W. Walker, M. Chiesi, W. Schilling, K.G. Hofbauer, N. Levens, Food intake in free-feeding and energy-deprived lean rats is mediated by the neuropeptide Y5 receptor, J. Clin. Invest. 102 (12) (1998) 2136-2145.
6. Y. Date, Y. Ueta, H. Yamashita, H. Yamaguchi, S. Matsukura, K. Kangawa, T. Sakurai, M. Yanagisawa, M. Nakazato, Orexins, orexigenic hypothalamic peptides, interact with autonomie, neuroendocrine and neuroregulatory systems, Proc. Natl. Acad. Sci. USA 96 (2) (1999) 748-753.
7. L. Davies, J.L. Marks, Role of hypothalamic neuropeptide Y gene expression in body weight regulation, Am. J. Physiol. 266 (5 Pt 2) (1994) R1687-1691.
8. L. de Lecea, T.S. Kilduff, C. Peyron, X. Gao, P.E. Foye, P.E. Danielson, C. Fukuhara, E.L. Battenberg, V.T. Gautvik, F.S. Bartlett 2nd, W.N. Frankel, A.N. van den Pol, F.E. Bloom, K.M. Gautvik, J.G. Sutcliffe, The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity, Proc. Nat. Acad. Sci. USA 95 (1) (1998) 322-327.
9. C.M. Edwards, S. Abusnana, D. Sunter, K.G. Murphy, M.A. Ghatei, S.R. Bloom, The effect of the orexins on food intake: comparison with neuropeptide Y, melanin-concentrating hormone and galanin, J. Endocrinol. 160 (3) (1999) R7-12.
10. C.F. Elias, C.B. Saper, E. Maratos-Flier, N.A. Tritos, C. Lee, J. Kelly, J.B. Tatro, G.E. Hoffman, M.M. Ollmann, O.S. Barsh, T. Sakurai, M. Yanagisawa, J.K. Elmquist, Chemically defined projections linking the mediobasal hypothalamus and the lateral hypothalamic area, J. Comp. Neurol. 402 (4) (1998) 442-459.
11. J.C. Erickson, K.E. Clegg, R.D. Palmiter, Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y, Nature 381 (6581) (1996) 415-421.
12. A.C. Haynes, J.R. Arch, S. Wilson, S. McClue, R.E. Buckingham, Characterisation of the neuropeptide Y receptor that mediates feeding in the rat: a role for the Y5 receptor?, Regul. Pept. 75 (1998) 355-361.
13. T.L. Horvath, S. Diano, A.N. van den Pol, Synaptic interaction between hypocretin (orexin) and neuropeptide Y cells in the rodent and primate hypothalamus: a novel circuit implicated in metabolic and endocrine regulations, J. Neurosci 19 (3) (1999) 1072-1087.
14. A. Kanatani, J. Ito, A. Ishihara, H. Iwaasa, T. Fukuroda, T. Fukami, D.J. MacNeil, L.H. Van der Ploeg, M. Ihara, NPY-induced feeding involves the action of a Y1-like receptor in rodents, Regul. Pept. 75 (1998) 409-415.
15. J.H. Kordower, H.K. Le, E.J. Mufson, Galanin immunoreactivity in the primate central nervous system, J. Comp. Neurol. 319 (4) (1992) 479-500.
16. M.C. Michel, A. Beck-Sickinger, H. Cox, H.N. Doods, H. Herzog, D. Larhammar, R. Quirion, T. Schwartz, T. Westfall, International Union of Pharmacology recommendations for the nomenclature of neuropeptide Y, peptide YY, and pancreatic polypeptide receptors, Pharmacol. Rev. 50 (1) (1998) 143-150.
17. T. Nambu, T. Sakurai, K. Mizukami, Y. Hosoya, M. Yanagisawa, K. Goto, Distribution of orexin neurons in the adult rat brain, Brain Res. 827 (1) (1999) 243-260.
18. D.J. Marsh, G. Hollopeter, K.E. Kafer, R.D. Palmiter, Role of the Y5 neuropeptide Y receptor in feeding and obesity, Nat. Med. 4 (6) (1998) 718-721.
19. C. Peyron, D.K. Tighe, A.N. van den Pol, L. de Lecea, H.C. Heller, J.G. Sutcliffe, T.S. Kilduff, Neurons containing hypocretin (orexin) project to multiple neuronal systems, J. Neurosci. 18 (23) (1998) 9996-10015.
20. T.J. Sajdyk, M.G. Vandergriff, D.R. Gehlert, Amygdalar neuropeptide Y Y1 receptors mediate the anxiolytic-like actions of neuropeptide Y in the social interaction test, Eur. J. Pharmacol. 368 (2) (1999) 143-147.
21. T. Sakurai, A. Amemiya, M. Ishii, I. Matsuzaki, R.M. Chemelli, H. Tanaka, S.C. Williams, J.A. Richardson, G.P. Kozlowski, S. Wilson, J.R. Arch, R.E. Buckingham, A.C. Haynes, S.A. Carr, R.S. Annan, D.E. Mcnulty, W.S. Liu, J.A. Terrett, N.A. Elshourbagy, D.J. Bergsma, M. Yanagisawa, Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behaviour, Cell 92 (4) (1998) 573-585.
22. A.O. Schaffhauser, A. Stricker-Krongrad, L. Brunner, F. Cumin, C. Gerald, S. Whitebread, L. Criscione, K.G. Hofbauer, Inhibition of food intake by neuropeptide Y Y5 receptor antisense oligodeoxynucleotides, Diabetes 46 (11) (1997) 1792-1798.
23. J.T. Clark, P.S. Kalra, W.R. Crowley, S.P. Kalra, Neuropeptide Y and human pancreatic polypeptide stimulate feeding behavior in rats, Endocrinology 115 (1) (1984) 427-429.
24. H.A. Wieland, W. Engel, W. Eberlein, K. Rudolf, H.N. Doods, Subtype selectivity of the novel nonpeptide neuropeptide Y Yl receptor antagonist BIBO 3304 and its effect on feeding in rodents, Br. J. Pharmacol. 125 (3) (1998) 549-555.
25. T. Yoshihara, S. Honma, K. Honma, Effects of restricted daily feeding on neuropeptide Y release in the rat paraventricular nucleus, Am. J. Physiol. 270 (4 Pt 1) (1996) E589-595.