Neurons containing orexin in the lateral hypothalamic area of the adult rat brain are activated by insulin-induced acute hypoglycemia

Neuroscience Letters

Volumn 264, Issue 1-3, 1999, Pages 101-104

  Moriguchi, Takashi ^a   Sakurai, Takeshi ^a   Nambu, Tadahiro ^a   Yanagisawa, Masashi ^b   Goto, Katsutoshi ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

C fos; Glucose sensitive neuron; Hypoglycemia; Immunohistochemistry; Orexins

Indexed keywords

NEUROPEPTIDE;

ANIMAL TISSUE; ARTICLE; GLUCOSE BLOOD LEVEL; HYPOGLYCEMIA; HYPOTHALAMUS; INSULIN METABOLISM; NONHUMAN; ONCOGENE C FOS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT;

ANIMALS; CARRIER PROTEINS; HYPOGLYCEMIA; HYPOGLYCEMIC AGENTS; HYPOTHALAMIC AREA, LATERAL; IMMUNOHISTOCHEMISTRY; INSULIN; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; NEURONS; NEUROPEPTIDES; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, WISTAR;

EID: 0033515711     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(99)00177-9     Document Type: Article

References (17)

1. Bahjaoui-Bouhaddi M., Fellmann D., Bugnon C. Induction of Fos-immunoreactivity in prolactin-like containing neurons of the rat lateral hypothalamus after insulin treatment. Neurosci. Lett. 168:1994;11-15.
2. Bahjaoui-Bouhaddi M., Fellmann D., Griffond B., Bugnon C. Insulin treatment stimulates the rat melanin-concentrating hormone-producing neurons. Neuropeptides. 27:1994;251-258.
3. Bernardis L.L., Bellinger L.L. The lateral hypothalamic area revisited: neuroanatomy, body weight regulation, neuroendocrinology and metabolism. Neurosci. Biobehav. Rev. 17:1993;141-193.
4. Bernardis L.L., Bellinger L.L. The lateral hypothalamic area revisited: ingestive behavior. Neurosci. Biobehav. Rev. 20:1996;189-287.
5. Date Y., Ueta Y., Yamashita H., Yamaguchi H., Matsukura S., Kangawa K., Sakurai T., Yanagisawa M., Nakazato M. Orexins, novel orexigenic hypothalamic peptides, interact with autonomic, neuroendocrine and neuroregulatory systems. Proc. Natl. Acad. Sci. USA. 96(2):1999;748-753.
6. De Lecea L., Kilduff T.S., Peyron C., Gao X., Foye P.E., Danielson P.E., Fukuhara C., Battenberg E.L., Gautvik V.T., Bartlett II F.S., Frankel W.N., Van den Pol A.N., Bloom F.E., Gautvik K.M., Sutcliffe J.G. The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity. Proc. Natl. Acad. Sci. USA. 95(1):1998;322-327.
7. Guthrie K.M., Gall C.M. Odors increase Fos in olfactory bulb neurons including dopaminergic cells. NeuroReport. 6:1995;2145-2149.
8. Himmi T., Boyer A., Orsini J.C. Changes in lateral hypothalamic neuronal activity accompanying hyper- and hypoglycemias. Physiol. Behav. 44:1988;347-354.
9. Lachuer J., Gaillet S., Barbagli B., Buda M., Tappaz M. Differential early time course activation of the brainstem catecholaminergic groups in response to various stresses. Neuroendocrinology. 53:1991;589-596.
10. Marks J.L., Porte D. Jr., Stahl W.L., Baskin D.G. Localization of insulin receptor mRNA in rat brain by in situ hybridization. Endocrinology. 127:1990;3234-3236.
11. Morgan J.I., Curran T. Stimulus-transcription coupling in the nervous system: involvement of the inducible proto-oncogenes fos and jun. Annu. Rev. Neurosci. 14:1991;421-451.
12. Niimi M., Sato M., Tamaki M., Wada Y., Takahara J., Kawanishi K. Induction of Fos protein in the rat hypothalamus elicited by insulin-induced hypoglycemia. Neurosci. Res. 23:1995;361-364.
13. Oomura Y., Ono T., Ooyama H., Wayner M.J. Neurones of the rat hypothalamus. Nature. 222:1969;282-284.
14. Oomura Y., Ooyama H., Sugimori M., Nakamura T., Yamada Y. Glucose inhibition of the glucose-sensitive neurone in the rat lateral hypothalamus. Nature. 247:1974;284-286.
15. Qu D., Ludwig D.S., Gammeltoft S., Piper M., Pelleymounter M.A., Cullen M.J., Mathes W.F., Przypek R., Kanarek R., Maratos-Flier E. A role for melanin-concentrating hormone in the central regulation of feeding behaviour. Nature. 380:1996;243-247.
16. Sakurai T., Amemiya A., Ishii M., Matsuzaki I., Chemelli R.M., Tanaka H., Williams S.C., Richarson J.A., Kozlowski G.P., Wilson S., Arch J.R., Buckingham R.E., Haynes A.C., Carr S.A., Annan R.S., McNulty D.E., Liu W.S., Terrett J.A., Elshourbagy N.A., Bergsma D.J., Yanagisawa M. Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior (comment). Cell. 92(4):1998;573-585.
17. Trivedi P., Yu H., MacNeil D.J., Van der Ploeg L.H.T., Guan X. Distribution of orexin receptor mRNA in the rat brain. FEBS Lett. 438:1998;71-75.