Identification of GAS1 as an epirubicin resistance-related gene in human gastric cancer cells with a partially randomized small interfering RNA library

Journal of Biological Chemistry

Volumn 284, Issue 39, 2009, Pages 26273-26285

  Zhao, Lina ^a   Pan, Yanglin ^a   Gang, Yi ^a   Wang, Honghong ^a   Jin, Haifeng ^a   Tie, Jun ^a   Xia, Lin ^a   Zhang, Yongguo ^a   He, Lijie ^a   Yao, Liping ^a   Qiao, Taidong ^a,b   Liu, Zhiguo ^a   Fan, Daiming ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

5-FLUOROURACIL; APOPTOSIS; ATP-BINDING CASSETTE TRANSPORTERS; BREAST CANCER RESISTANCE PROTEINS; CANDIDATE GENES; CHEMORESISTANCE; CHEMOTHERAPEUTIC TREATMENTS; CIS-PLATIN; DOWN-REGULATION; EPIRUBICIN; GASTRIC CANCER CELL LINES; GASTRIC CANCER CELLS; GASTRIC CANCERS; GROWTH ARREST; MULTIDRUG RESISTANCE; P-GLYCOPROTEIN; RESISTANT CELLS; SGC7901; SMALL INTERFERING RNA; SUCCESSFUL MANAGEMENT; VERAPAMIL;

CELL CULTURE; CELL DEATH; CELL MEMBRANES; GENES; GLYCOPROTEINS; NUCLEIC ACIDS; RNA;

PLATINUM COMPOUNDS;

ABC TRANSPORTER; BINDING PROTEIN; BREAST CANCER RESISTANCE PROTEIN; CISPLATIN; EPIRUBICIN; FLUOROURACIL; GLYCOPROTEIN P; GROWTH ARREST SPECIFIC PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 1; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN BAX; PROTEIN BCL 2; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; VERAPAMIL;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CONTROLLED STUDY; CROSS RESISTANCE; DOWN REGULATION; DRUG TRANSPORT; GENE IDENTIFICATION; GENE LIBRARY; HUMAN; HUMAN CELL; INHIBITION KINETICS; MULTIDRUG RESISTANCE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN TARGETING; RETROVIRUS; STOMACH CANCER; UPREGULATION;

ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; ATP-BINDING CASSETTE TRANSPORTERS; BASE SEQUENCE; BCL-2-ASSOCIATED X PROTEIN; BLOTTING, WESTERN; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL SURVIVAL; CISPLATIN; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; EPIRUBICIN; FLOW CYTOMETRY; FLUOROURACIL; GENE LIBRARY; HUMANS; MEMBRANE PROTEINS; MOLECULAR SEQUENCE DATA; NEOPLASM PROTEINS; P-GLYCOPROTEIN; PROTO-ONCOGENE PROTEINS C-BCL-2; PTEN PHOSPHOHYDROLASE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; STOMACH NEOPLASMS; TRANSFECTION;

EID: 70350400865     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.028068     Document Type: Article

References (73)

1. Cunningham, D., Allum, W. H., Stenning, S. P., Thompson, J. N., Van de Velde, C. J., Nicolson, M., Scarffe, J. H., Lofts, F. J., Falk, S. J., Iveson, T. J., Smith, D. B., Langley, R. E., Verma, M., Weeden, S., Chua, Y. J., and MAGIC, Trial, Participants (2006) N. Engl. J. Med. 355, 11-20
2. Macdonald, J. S. (2006) N. Engl. J. Med. 355, 76-77
3. Zhang, C. X., Huang, S., Xu, N., Fang, J. W., Shen, P., Bao, Y. H., Mou, B. H., Shi, M. G., Zhong, X. L., and Xiong, P. J. (2007) Anticancer Drugs 18, 581-586
4. Liu, H., Li, N., Yao, L., Jiang, L., Bao, G., Li, J., Ma, Q., and Liu, Z. (2008) Oncol. Rep. 20, 963-969
5. Zhang, D., and Fan, D. (2007) Expert Rev. Anticancer Ther. 7, 1369-1378
6. Zhao, Y., You, H., Liu, F., An, H., Shi, Y., Yu, Q., and Fan, D. (2002) Cancer Lett. 185, 211-218
7. Silva, J., Chang, K., Hannon, G. J., and Rivas, F. V. (2004) Oncogene 23, 8401-8409
8. Singer, O., Yanai, A., and Verma, I. M. (2004) Proc. Natl. Acad. Sci. U.S.A. 101, 5313-5314
9. Bartz, S. R., Zhang, Z., Burchard, J., Imakura, M., Martin, M., Palmieri, A., Needham, R., Guo, J., Gordon, M., Chung, N., Warrener, P., Jackson, A. L., Carleton, M., Oatley, M., Locco, L., Santini, F., Smith, T., Kunapuli, P., Ferrer, M., Strulovici, B., Friend, S. H., and Linsley, P. S. (2006) Mol. Cell. Biol. 26, 9377-9386
10. Liang, Z. (2005) IDrugs 8, 924-926
11. Root, D. E., Hacohen, N., Hahn, W. C., Lander, E. S., and Sabatini, D. M. (2006) Nat. Methods 3, 715-719
12. Matsumoto, S., Miyagishi, M., and Taira, K. (2007) Methods Mol. Biol. 360, 131-142
13. Cullen, L. M., and Arndt, G. M. (2005) Immunol. Cell Biol. 83, 217-223
14. Blow, N. (2008) Nat. Meth. 5, 361-368
15. Huang, R. Y., Eddy, M., Vujcic, M., and Kowalski, D. (2005) Cancer Res. 65, 5890-5897
16. Aza-Blanc, P., Cooper, C. L., Wagner, K., Batalov, S., Deveraux, Q. L., and Cooke, M. P. (2003) Mol. Cell 12, 627-637
17. MacKeigan, J. P., Murphy, L. O., and Blenis, J. (2005) Nat. Cell Biol. 7, 591-600
18. Silva, J. M., Marran, K., Parker, J. S., Silva, J., Golding, M., Schlabach, M. R., Elledge, S. J., Hannon, G. J., and Chang, K. (2008) Science 319, 617-620
19. Schlabach, M. R., Luo, J., Solimini, N. L., Hu, G., Xu, Q., Li, M. Z., Zhao, Z., Smogorzewska, A., Sowa, M. E., Ang, X. L., Westbrook, T. F., Liang, A. C., Chang, K., Hackett, J. A., Harper, J. W., Hannon, G. J., and Elledge, S. J. (2008) Science 319, 620-624
20. Bernards, R., Brummelkamp, T. R., and Beijersbergen, R. L. (2006) Nat. Methods 3, 701-706
21. Berns, K., Hijmans, E. M., Mullenders, J., Brummelkamp, T. R., Velds, A., Heimerikx, M., Kerkhoven, R. M., Madiredjo, M., Nijkamp, W., Weigelt, B., Agami, R., Ge, W., Cavet, G., Linsley, P. S., Beijersbergen, R. L., and Bernards, R. (2004) Nature 428, 431-437
22. Ngo, V. N., Davis, R. E., Lamy, L., Yu, X., Zhao, H., Lenz, G., Lam, L. T., Dave, S., Yang, L., Powell, J., and Staudt, L. M. (2006) Nature 441, 106-110
23. Kolfschoten, I. G., van Leeuwen, B., Berns, K., Mullenders, J., Beijersbergen, R. L., Bernards, R., Voorhoeve, P. M., and Agami, R. (2005) Cell 121, 849-858
24. Westbrook, T. F., Martin, E. S., Schlabach, M. R., Leng, Y., Liang, A. C., Feng, B., Zhao, J. J., Roberts, T. M., Mandel, G., Hannon, G. J., Depinho, R. A., Chin, L., and Elledge, S. J. (2005) Cell 121, 837-848
25. Huesken, D., Lange, J., Mickanin, C., Weiler, J., Asselbergs, F., Warner, J., Meloon, B., Engel, S., Rosenberg, A., Cohen, D., Labow, M., Reinhardt, M., Natt, F., and Hall, J. (2005) Nat. Biotechnol. 23, 995-1001
26. Pan, Y., Zhao, L., Liang, J., Liu, J., Shi, Y., Liu, N., Zhang, G., Jin, H., Gao, J., Xie, H., Wang, J., Liu, Z., and Fan, D. (2006) FASEB J. 20, 1886-1888
27. Livak, K. J., and Schmittgen, T. D. (2001) Methods 25, 402-408
28. Dorn, A., Graf, N., and Pees, H. W. (1993) Padiatr. Padol. 28, 157-163
29. Dahlgren, C., Zhang, H. Y., Du, Q., Grahn, M., Norstedt, G., Wahlestedt, C., and Liang, Z. (2008) Nucleic Acids Res. 36, e53
30. Du, Q., Thonberg, H., Wang, J., Wahlestedt, C., and Liang, Z. (2005) Nucleic Acids Res. 33, 1671-1677
31. Yu, H. G., Ai, Y. W., Yu, L. L., Zhou, X. D., Liu, J., Li, J. H., Xu, X. M., Liu, S., Chen, J., Liu, F., Qi, Y. L., Deng, Q., Cao, J., Liu, S. Q., Luo, H. S., and Yu, J. P. (2008) Int. J. Cancer 122, 433-443
32. Oki, E., Baba, H., Tokunaga, E., Nakamura, T., Ueda, N., Futatsugi, M., Mashino, K., Yamamoto, M., Ikebe, M., Kakeji, Y., and Maehara, Y. (2005) Int. J. Cancer 117, 376-380
33. Du, J. P., Jin, X. H., Shi, Y. Q., Zhao, Y. Q., Liu, C. J., Cao, Y. X., Qiao, T. D., Chen, B. J., and Fan, D. M. (2003) Zhonghua Yi. Xue. Za Zhi. 83, 328-332
34. Plati, J., Bucur, O., and Khosravi-Far, R. (2008) J. Cell. Biochem. 104, 1124-1149
35. Zamorano, A., Mellström, B., Vergara, P., Naranjo, J. R., and Segovia, J. (2004) Neurobiol. Dis. 15, 483-491
36. Zamorano, A., Lamas, M., Vergara, P., Naranjo, J. R., and Segovia, J. (2003) J. Neurosci. Res. 71, 256-263
37. Stavrovskaya, A. A., and Stromskaya, T. P. (2008) Biochemistry 73, 592-604
38. Chen, M., Zhang, L., Zhang, H. Y., Xiong, X., Wang, B., Du, Q., Lu, B., Wahlestedt, C., and Liang, Z. (2005) Proc. Natl. Acad. Sci. U.S.A. 102, 2356-2361
39. Guo, Q., Kong, Y., Fu, L., Yu, T., Xu, J., and Chen, W. (2007) Biochem. Biophys. Res. Commun. 358, 272-276
40. Wang, Y., Wang, Y. E., Cotticelli, M. G., and Wilson, R. B. (2008) PLoS ONE. 3, e3171
41. Wu, H., Dinh, A., and Mo, Y. Y. (2007) Biol. Proced. Online 9, 9-17
42. Buchholz, F., Kittler, R., Slabicki, M., and Theis, M. (2006) Nat. Methods 3, 696-700
43. Luo, B., Heard, A. D., and Lodish, H. F. (2004) Proc. Natl. Acad. Sci. U.S.A. 101, 5494-5499
44. Shirane, D., Sugao, K., Namiki, S., Tanabe, M., Iino, M., and Hirose, K. (2004) Nat. Genet. 36, 190-196
45. Sen, G., Wehrman, T. S., Myers, J. W., and Blau, H. M. (2004) Nat. Genet. 36, 183-189
46. Paddison, P. J., Silva, J. M., Conklin, D. S., Schlabach, M., Li, M., Aruleba, S., Balija, V., O'Shaughnessy, A., Gnoj, L., Scobie, K., Chang, K., Westbrook, T., Cleary, M., Sachidanandam, R., McCombie, W. R., Elledge, S. J., and Hannon, G. J. (2004) Nature 428, 427-431
47. Zheng, L., Liu, J., Batalov, S., Zhou, D., Orth, A., Ding, S., and Schultz, P. G. (2004) Proc. Natl. Acad. Sci. U.S.A. 101, 135-140
48. Yu, J. Y., DeRuiter, S. L., and Turner, D. L. (2002) Proc. Natl. Acad. Sci. U.S.A. 99, 6047-6052
49. Paddison, P. J., Caudy, A. A., and Hannon, G. J. (2002) Proc. Natl. Acad. Sci. U.S.A. 99, 1443-1448
50. Kaykas, A., and Moon, R. T. (2004) BMC Cell Biol. 5, 16
51. Miyagishi, M., and Taira, K. (2003) Oligonucleotides 13, 325-333
52. Siolas, D., Lerner, C., Burchard, J., Ge, W., Linsley, P. S., Paddison, P. J., Hannon, G. J., and Cleary, M. A. (2005) Nat. Biotechnol. 23, 227-231
53. Reynolds, A., Anderson, E. M., Vermeulen, A., Fedorov, Y., Robinson, K., Leake, D., Karpilow, J., Marshall, W. S., and Khvorova, A. (2006) RNA 12, 988-993
54. Chen, M., Du, Q., Zhang, H. Y., Wang, X., and Liang, Z. (2007) Expert Rev. Mol. Diagn. 7, 281-291
55. Fewell, G. D., and Schmitt, K. (2006) Drug Discov. Today 11, 975-982
56. Li, W., and Cha, L. (2007) Cell. Mol. Life Sci. 64, 1785-1792
57. Sherbakova, E. A., Stromskaia, T. P., Rybalkina, E. I., Kalita, O. V., and Stavrovskaia, A. A. (2008) Mol. Biol. (Mosk.) 42, 487-493
58. Steelman, L. S., Navolanic, P. M., Sokolosky, M. L., Taylor, J. R., Lehmann, B. D., Chappell, W. H., Abrams, S. L., Wong, E. W., Stadelman, K. M., Terrian, D. M., Leslie, N. R., Martelli, A. M., Stivala, F., Libra, M., Franklin, R. A., and McCubrey, J. A. (2008) Oncogene 27, 4086-4095
59. Stebel, M., Vatta, P., Ruaro, M. E., Del Sal, G., Parton, R. G., and Schneider, C. (2000) FEBS Lett. 481, 152-158
60. Del Sal, G., Ruaro, M. E., Philipson, L., and Schneider, C. (1992) Cell 70, 595-607
61. Martinelli, D. C., and Fan, C. M. (2007) Cell Cycle 6, 2650-2655
62. Konishi, T., Sasaki, S., Watanabe, T., Kitayama, J., and Nagawa, H. (2006) Oncogene 25, 3160-3169
63. Lei, X. Y., Zhong, M., Feng, L. F., Zhu, B. Y., Tang, S. S., and Liao, D. F. (2007) Clin. Exp. Pharmacol. Physiol. 34, 450-456
64. Villar, J., Quadri, H. S., Song, I., Tomita, Y., Tirado, O. M., and Notario, V. (2009) Cancer Res. 69, 102-110
65. Kim, R., Emi, M., Tanabe, K., and Toge, T. (2004) Cancer 101, 2177-2186
66. Michaud, W. A., Nichols, A. C., Mroz, E. A., Faquin, W. C., Clark, J. R., Begum, S., Westra, W. H., Wada, H., Busse, P. M., Ellisen, L. W., and Rocco, J. W. (2009) Clin. Cancer Res. 15, 1645-1654
67. Spagnuolo, R., Corada, M., Orsenigo, F., Zanetta, L., Deuschle, U., Sandy, P., Schneider, C., Drake, C. J., Breviario, F., and Dejana, E. (2004) Blood 103, 3005-3012
68. Gobeil, S., Zhu, X., Doillon, C. J., and Green, M. R. (2008) Genes Dev. 22, 2932-2940
69. Domínguez-Monzón, G., Benítez, J. A., Vergara, P., Lorenzana, R., and Segovia, J. (2009) Int. J. Dev. Neurosci. 27, 305-313
70. Yuan, J., Lv, H., Peng, B., Wang, C., Yu, Y., and He, Z. (2009) Cancer Chemother. Pharmacol. 63, 1103-1110
71. López-Ramírez, M. A., Domínguez-Monzón, G., Vergara, P., and Segovia, J. (2008) Int. J. Dev. Neurosci. 26, 497-503
72. Martinelli, D. C., and Fan, C. M. (2007) Genes Dev. 21, 1231-1243
73. Sims-Mourtada, J., Izzo, J. G., Ajani, J., and Chao, K. S. (2007) Oncogene 26, 5674-5679