메뉴 건너뛰기




Volumn 3, Issue 9, 2008, Pages

A random shRNA-encoding library for phenotypic selection and hit-optimization

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 3; NUCLEOTIDE; SHORT HAIRPIN RNA; CASPASE 3; MICRORNA; SMALL INTERFERING RNA;

EID: 52649136113     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0003171     Document Type: Article
Times cited : (13)

References (32)
  • 1
    • 26944441255 scopus 로고    scopus 로고
    • Dicing and slicing: The core machinery of the RNA interference pathway
    • Hammond SM (2005) Dicing and slicing: the core machinery of the RNA interference pathway. FEBS Lett 579: 5822-5829.
    • (2005) FEBS Lett , vol.579 , pp. 5822-5829
    • Hammond, S.M.1
  • 2
    • 13944282215 scopus 로고    scopus 로고
    • Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
    • Lim LP, Lau NC, Garrett-Engele P, Grimson A, Schelter JM, et al. (2005) Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 433: 769-773.
    • (2005) Nature , vol.433 , pp. 769-773
    • Lim, L.P.1    Lau, N.C.2    Garrett-Engele, P.3    Grimson, A.4    Schelter, J.M.5
  • 3
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • Lewis BP, Burge CB, Bartel DP (2005) Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120: 15-20.
    • (2005) Cell , vol.120 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 4
    • 0033572284 scopus 로고    scopus 로고
    • The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation
    • Olsen PH, Ambros V (1999) The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation. Dev Biol 216: 671-680.
    • (1999) Dev Biol , vol.216 , pp. 671-680
    • Olsen, P.H.1    Ambros, V.2
  • 5
    • 0037085968 scopus 로고    scopus 로고
    • Two genetic circuits repress the Caenorhabditis elegans heterochronic gene lin-28 after translation initiation
    • Seggerson K, Tang L, Moss EG (2002) Two genetic circuits repress the Caenorhabditis elegans heterochronic gene lin-28 after translation initiation. Dev Biol 243: 215-225.
    • (2002) Dev Biol , vol.243 , pp. 215-225
    • Seggerson, K.1    Tang, L.2    Moss, E.G.3
  • 6
    • 1242296375 scopus 로고    scopus 로고
    • miRNP:mRNA association in polyribosomes in a human neuronal cell line
    • Nelson PT, Hatzigeorgiou AG, Mourelatos Z (2004) miRNP:mRNA association in polyribosomes in a human neuronal cell line. Rna 10: 387-394.
    • (2004) Rna , vol.10 , pp. 387-394
    • Nelson, P.T.1    Hatzigeorgiou, A.G.2    Mourelatos, Z.3
  • 7
    • 2442495329 scopus 로고    scopus 로고
    • RISC is a 5′ phosphomonoester-producing RNA endonuclease
    • Martinez J, Tuschl T (2004) RISC is a 5′ phosphomonoester-producing RNA endonuclease. Genes Dev 18: 975-980.
    • (2004) Genes Dev , vol.18 , pp. 975-980
    • Martinez, J.1    Tuschl, T.2
  • 8
    • 3042602447 scopus 로고    scopus 로고
    • Kinetic analysis of the RNAi enzyme complex
    • Haley B, Zamore PD, (2004) Kinetic analysis of the RNAi enzyme complex. Nat Struct Mol Biol 11: 599-606.
    • (2004) Nat Struct Mol Biol , vol.11 , pp. 599-606
    • Haley, B.1    Zamore, P.D.2
  • 11
    • 36749026906 scopus 로고    scopus 로고
    • Switching from repression to activation: MicroRNAs can up-regulate translation
    • Vasudevan S, Tong Y, Steitz JA (2007) Switching from repression to activation: microRNAs can up-regulate translation. Science 318: 1931-1934.
    • (2007) Science , vol.318 , pp. 1931-1934
    • Vasudevan, S.1    Tong, Y.2    Steitz, J.A.3
  • 13
    • 0042467554 scopus 로고    scopus 로고
    • Loss of the cylindromiatosis tumour suppressor inhibits apoptosis by activating NF-kappaB
    • Brummelkamp TR, Nijman SM, Dirac AM, Bernards R (2003) Loss of the cylindromiatosis tumour suppressor inhibits apoptosis by activating NF-kappaB. Nature 424: 797-801.
    • (2003) Nature , vol.424 , pp. 797-801
    • Brummelkamp, T.R.1    Nijman, S.M.2    Dirac, A.M.3    Bernards, R.4
  • 14
    • 2342564353 scopus 로고    scopus 로고
    • A library of siRNA duplexes targeting the phosphoinositide 3-kinase pathway: Determinants of gene silencing for use in cell-based screens
    • Hsieh AC, Bo, R, Manola J, Vazquez F, Bare O, et al. (2004) A library of siRNA duplexes targeting the phosphoinositide 3-kinase pathway: determinants of gene silencing for use in cell-based screens. Nucleic Acids Res 32: 893-901.
    • (2004) Nucleic Acids Res , vol.32 , pp. 893-901
    • Hsieh, A.C.1    Bo, R.2    Manola, J.3    Vazquez, F.4    Bare, O.5
  • 15
    • 12144289681 scopus 로고    scopus 로고
    • A large-scale RNAi screen in human cells identifies new components of the p53 pathway
    • Berns K., Hijmans EM, Mullenders J, Brummelkamp TR, Velds A, et al. (2004) A large-scale RNAi screen in human cells identifies new components of the p53 pathway. Nature 428: 431-437.
    • (2004) Nature , vol.428 , pp. 431-437
    • Berns, K.1    Hijmans, E.M.2    Mullenders, J.3    Brummelkamp, T.R.4    Velds, A.5
  • 16
    • 12144288006 scopus 로고    scopus 로고
    • A resource for large-scale RNA-interference-based screens in mammals
    • Paddison PJ, Silva JM, Conklin DS, Schlabach M, Li M, et al. (2004) A resource for large-scale RNA-interference-based screens in mammals. Nature 428: 427-431.
    • (2004) Nature , vol.428 , pp. 427-431
    • Paddison, P.J.1    Silva, J.M.2    Conklin, D.S.3    Schlabach, M.4    Li, M.5
  • 17
    • 27644436787 scopus 로고    scopus 로고
    • Second-generation shRNA libraries covering the mouse and human genomes
    • Silva JM, Li MZ, Chang K, Ge W, Golding MC, et al. (2005) Second-generation shRNA libraries covering the mouse and human genomes. Nat Genet 37: 1281-1288.
    • (2005) Nat Genet , vol.37 , pp. 1281-1288
    • Silva, J.M.1    Li, M.Z.2    Chang, K.3    Ge, W.4    Golding, M.C.5
  • 18
    • 1842631431 scopus 로고    scopus 로고
    • Small interfering RNA production by enzymatic engineering of DNA (SPEED)
    • Luo B, Heard AD, Lodish HF (2004) Small interfering RNA production by enzymatic engineering of DNA (SPEED). Proc Natl Acad Sci U S A 101: 5494-5499.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 5494-5499
    • Luo, B.1    Heard, A.D.2    Lodish, H.F.3
  • 19
    • 0842310832 scopus 로고    scopus 로고
    • Restriction enzyme-generated siRNA (REGS) vectors and libraries
    • Sen G, Wehrman TS, Myers JW, Blau HM (2004) Restriction enzyme-generated siRNA (REGS) vectors and libraries. Nat Genet 36: 183-189.
    • (2004) Nat Genet , vol.36 , pp. 183-189
    • Sen, G.1    Wehrman, T.S.2    Myers, J.W.3    Blau, H.M.4
  • 20
    • 0842332405 scopus 로고    scopus 로고
    • Enzymatic production of RNAi libraries from cDNAs
    • Shirane D, Sugao K, Namiki S, Tanabe M, Lino M, et al. (2004) Enzymatic production of RNAi libraries from cDNAs. Nat Genet 36: 190-196.
    • (2004) Nat Genet , vol.36 , pp. 190-196
    • Shirane, D.1    Sugao, K.2    Namiki, S.3    Tanabe, M.4    Lino, M.5
  • 21
    • 19944367565 scopus 로고    scopus 로고
    • An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division
    • Kittler R, Putz G, Pelletier L, Poser I, Heninger AK, et al. (2004) An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division. Nature 432: 1036-1040.
    • (2004) Nature , vol.432 , pp. 1036-1040
    • Kittler, R.1    Putz, G.2    Pelletier, L.3    Poser, I.4    Heninger, A.K.5
  • 22
    • 14044272863 scopus 로고    scopus 로고
    • A universal plasmid library encoding all permutations of small interfering RNA
    • Chen M, Zhang L, Zhang HY, Xiong X, Wang B, et al. (2005) A universal plasmid library encoding all permutations of small interfering RNA. Proc Natl Acad Sci U S A 102: 2356-2361.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 2356-2361
    • Chen, M.1    Zhang, L.2    Zhang, H.Y.3    Xiong, X.4    Wang, B.5
  • 23
    • 36849037941 scopus 로고    scopus 로고
    • Potency of siRNA versus shRNA mediated knockdown in vivo
    • McAnuff MA, Rettig GR, Rice KG (2007) Potency of siRNA versus shRNA mediated knockdown in vivo. J Pharm Sci 96: 2922-2930.
    • (2007) J Pharm Sci , vol.96 , pp. 2922-2930
    • McAnuff, M.A.1    Rettig, G.R.2    Rice, K.G.3
  • 24
    • 0037197914 scopus 로고    scopus 로고
    • RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells
    • Yu JY, DeRuiter SL, Turner DL (2002) RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells. Proc Natl Acad Sci U S A 99: 6047-6052.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 6047-6052
    • Yu, J.Y.1    DeRuiter, S.L.2    Turner, D.L.3
  • 26
    • 13844281898 scopus 로고    scopus 로고
    • Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy
    • Kim DH, Behlke MA, Rose SD, Chang MS, Choi S, et al. (2005) Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy. Nat Biotechnol 23: 222-226.
    • (2005) Nat Biotechnol , vol.23 , pp. 222-226
    • Kim, D.H.1    Behlke, M.A.2    Rose, S.D.3    Chang, M.S.4    Choi, S.5
  • 27
    • 33646891110 scopus 로고    scopus 로고
    • Induction of the interferon response by siRNA is cell type- and duplex length-dependent
    • Reynolds A, Anderson EM, Vermeulen A, Fedorov Y, Robinson K, et al. (2006) Induction of the interferon response by siRNA is cell type- and duplex length-dependent. Rna 12: 988-993.
    • (2006) Rna , vol.12 , pp. 988-993
    • Reynolds, A.1    Anderson, E.M.2    Vermeulen, A.3    Fedorov, Y.4    Robinson, K.5
  • 28
    • 0032587982 scopus 로고    scopus 로고
    • Bcl-xL prevents cell death following growth factor withdrawal by facilitating mitochondrial ATP/ADP exchange
    • Vander Heiden MG, Chandel NS, Schumacker PT, Thompson CB (1999) Bcl-xL prevents cell death following growth factor withdrawal by facilitating mitochondrial ATP/ADP exchange. Mol Cell 3: 159-167.
    • (1999) Mol Cell , vol.3 , pp. 159-167
    • Vander Heiden, M.G.1    Chandel, N.S.2    Schumacker, P.T.3    Thompson, C.B.4
  • 29
    • 0023461786 scopus 로고
    • Mutagenesis with degenerate oligonucleotides: An efficient method for saturating a defined DNA region with base pair substitutions
    • Hill DE, Oliphant AR, Struhl K (1987) Mutagenesis with degenerate oligonucleotides: an efficient method for saturating a defined DNA region with base pair substitutions. Methods Enzymol 155: 558-568.
    • (1987) Methods Enzymol , vol.155 , pp. 558-568
    • Hill, D.E.1    Oliphant, A.R.2    Struhl, K.3
  • 30
    • 38449100768 scopus 로고    scopus 로고
    • Small RNAs: Delivering the future
    • Blow N (2007) Small RNAs: delivering the future. Nature 450: 1117-1120.
    • (2007) Nature , vol.450 , pp. 1117-1120
    • Blow, N.1
  • 31
    • 34447114618 scopus 로고    scopus 로고
    • Transvascular delivery of small interfering RNA to the central nervous system
    • Kumar P, Wu H, McBride JL, Jung KE, Kim MH, et al. (2007) Transvascular delivery of small interfering RNA to the central nervous system. Nature 448: 39-43.
    • (2007) Nature , vol.448 , pp. 39-43
    • Kumar, P.1    Wu, H.2    McBride, J.L.3    Jung, K.E.4    Kim, M.H.5
  • 32
    • 52649086837 scopus 로고    scopus 로고
    • Small RNAs: Table of suppliers
    • Blow N (2007) Small RNAs: Table of suppliers. Nature 450: 1121-1122.
    • (2007) Nature , vol.450 , pp. 1121-1122
    • Blow, N.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.