SB 239063, a p38 MAPK inhibitor, reduces neutrophilia, inflammatory cytokines, MMP-9, and fibrosis in lung

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 279, Issue 5 23-5, 2000, Pages

  Underwood, David C ^a   Osborn, Ruth R ^a   Bochnowicz, Steven ^a   Webb, Edward F ^a   Rieman, David J ^a   Lee, John C ^a   Romanic, Anne M ^a   Adams, Jerry L ^a   Hay, Douglas W P ^a   Griswold, Don E ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Alveolar macrophage; Bleomycin; Chronic obstructive pulmonary disease; Interleukin 6; Matrix metalloproteinase 9; Mitogen activated protein kinase

Indexed keywords

1 (4 HYDROXYCYCLOHEXYL) 4 (4 FLUOROPHENYL) 5 (2 METHOXYPYRIDIMIDIN 4 YL)IMIDAZOLE; 4 [4 (4 FLUOROPHENYL) 5 (2 METHOXY 4 PYRIMIDINYL) 1 IMIDAZOLYL]CYCLOHEXANOL; CYTOKINE; GELATINASE B; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOSE RESPONSE; DRUG EFFECT; ENZYME ACTIVITY; GUINEA PIG; HEART RIGHT VENTRICLE HYPERTROPHY; LUNG FIBROSIS; LUNG INFILTRATE; LUNG LAVAGE; MALE; NEUTROPHILIA; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 13844288120     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.2000.279.5.l895     Document Type: Article

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