Targeted Inhibition of p38 Mitogen-activated Protein Kinase Antagonizes Cardiac Injury and Cell Death Following Ischemia-Reperfusion in Vivo

Journal of Biological Chemistry

Volumn 279, Issue 15, 2004, Pages 15524-15530

  Kaiser, Robert A ^a   Bueno, Orlando F ^a   Lips, Daniel J ^b,c   Doevendans, Pieter A ^b,c   Jones, Fred ^a   Kimball, Thomas F ^a   Molkentin, Jeffery D ^a,d  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c Department of Cardiology   (Netherlands)

^d CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ENZYMES; FUNCTIONS; GENES; GENETIC ENGINEERING; SIGNALING;

APOPTOSIS; CELL DEATH; FUNCTIONAL EFFECTS; MUTANTS;

BIOCHEMISTRY;

DEOXYGLUCOSE; DNA NUCLEOTIDYLEXOTRANSFERASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38;

ADENOVIRUS; ANIMAL CELL; ARTICLE; CELL DEATH; CELL FUNCTION; DRUG ANTAGONISM; EFFECTOR CELL; ENZYME INHIBITION; ENZYME SPECIFICITY; GENE TARGETING; GENE TRANSFER; HEART INJURY; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART VENTRICLE PERFORMANCE; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY;

ADENOVIRIDAE; ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; BLOTTING, WESTERN; CELL CYCLE PROTEINS; CELL DEATH; CELLS, CULTURED; DEOXYGLUCOSE; DNA; DOWN-REGULATION; ECHOCARDIOGRAPHY; ENZYME ACTIVATION; ENZYME INHIBITORS; GENE TRANSFER TECHNIQUES; GENES, DOMINANT; IMMEDIATE-EARLY PROTEINS; IN SITU NICK-END LABELING; MICE; MICE, TRANSGENIC; MITOGEN-ACTIVATED PROTEIN KINASES; MUTATION; MYOCARDIUM; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHOPROTEIN PHOSPHATASE; PLASMIDS; PROTEIN-TYROSINE-PHOSPHATASE; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; REPERFUSION INJURY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

ADENOVIRIDAE; ANIMALIA; MUS MUSCULUS;

EID: 2442534165     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M313717200     Document Type: Article

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