Activation and inhibition of nuclear factor kappa B activity by cereal extracts: Role of dietary phenolic acids

Journal of Agricultural and Food Chemistry

Volumn 57, Issue 20, 2009, Pages 9481-9488

  Hole, Anastasia S ^a,b   Grimmer, Stine ^b   Naterstad, Kristine ^b   Jensen, Merete R ^b   Paur, Ingvild ^c   Johansen, Siril G ^c   Balstad, Trude R ^c   Blomhoff, Rune ^c   Sahlstrom, Stefan ^b  

^a NORWEGIAN UNIVERSITY OF LIFE SCIENCES   (Norway)

^b NOFIMA   (Norway)

^c UNIVERSITY OF OSLO   (Norway)

Author keywords

Cereal extract; Nuclear factor kappa B; Phenolic acids

Indexed keywords

HYDROXYBENZOIC ACID DERIVATIVE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHENOLIC ACID; PLANT EXTRACT;

ARTICLE; CEREAL; CHEMISTRY; DOWN REGULATION; DRUG ANTAGONISM; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; TUMOR CELL LINE; ANTAGONISTS AND INHIBITORS;

CELL LINE, TUMOR; CEREALS; DOWN-REGULATION; HUMANS; HYDROXYBENZOIC ACIDS; NF-KAPPA B; PLANT EXTRACTS; HYDROXYBENZOATES;

HORDEUM; TRITICUM AESTIVUM;

EID: 70350316495     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf9021459     Document Type: Article

References (48)

1. Kanauchi, O.; Andoh, A.; Iwanaga, T.; Fujiyama, Y.; Mitsuyama, K.; Toyonaga, A.; Banba, T. Germinated barley foodstuffs attenuate colonic mucosal damage and mucosal nuclear factor kappa B activity in a spontaneous colitis model. J. Gastroenterol. Hepatol. 1999, 74, 1173-1179.
2. Bongard, V.; Ruidavets, J. B.; Dallongeville, J,; Arveiler, D.; Ducimetiere, P.; Perret, B.; Ferneres, J. High consumption of cereals, fish and dairy products is associated with low prevalence of metabolic syndrome. Eur. Heart J. 2006, 27, 663-664.
3. La Vecchia, C.; Chatenoud, L.; Negri, E.; Franceschi, S. Session: Whole cereal grains, fibre and human cancer - Wholegrain cereals and cancer in Italy, Proc. Nutr. Soc. 2003, 62 (1), 45-49.
4. Monro, J. A. BSc (Hons) Dietary fibre content and nutrient claims relative to the faecal bulking efficacy of breakfast cereals. Asia Pac. J. Clin. Nutr. 2002, 11(4), 274-284.
5. Brennan, C. S.; Cleary, L. J. The potential use of cereal (1→3, 1→4)β-d-glucans as functional food ingredients. J. Cereal Chem. 2005, 42, 1-13.
6. (6) Běhali, K.; Scholfield, D.; Hallfrisch, J. Barley β-glucan reduces plasma glucose and insulin responses compared with resistant starch in men. Nutr. Res. 2006, 26, 644-650. (Pubitemid 44880523)
7. (7) Perez-Jimenez, J.; Saura-Calixto, F. Literature data may underestimate the actual antioxidant capacity of cereals. J. Agric. Food Chem. 2005, 53, 5036-5040. (Pubitemid 40937632)
8. (8) Peterson, D. M.; Hahn, M. J.; Emmons, C. L. Oat avenanthramides exhibit antioxidant activities in vitro. Food Chem. 2002, 79, 473-478. (Pubitemid 36160514)
9. Mattila, P.; Pihlava, J. M.; Hellstrom, J. Contents of phenolic acids, alkyl- and alkenylresorcinols, and avenanthramides in commercial grain products. J. Agric. Food Chem. 2005, 53, 8290-8295.
10. (10) Liyanapathirana, G; Shahidi, F. Antioxidant activity of wheat extracts as affected by in vitro digestion. BioFactors 2004, 21, 325-328. (Pubitemid 40921877)
11. Heiiien, M. M.; Hughes, M. C.; Ibiebele, T. I.; Marks, J. C.; Green, A. C.; Jolieke C., van der Pols Intake of antioxidant nutrients and the risk of skin cancer. Eur. J. Cancer 2007, 43, 2707-2716.
12. Serafini, M.; Bellocco, R.; Wolk, A. Total antioxidant potential of fruit and vegetables and risk, of gastric cancer. Gastroenterology 2002, 123 (A), 985-991.
13. Kris-Etherton, P. M.; Hecker, K. D.; Bonanome, A.; Coval, S. M.; Binkoski, A. E.; Hilpert, K. F.; Griel, A. E.; Terry, D. Bioactive compounds in foods: their role in the prevention of cardiovascular disease and cancer. Am, Am. J. Med. 2002, 113 (9), 71-88.
14. Liu, R. H. Whole grain phytochemicals and health. J. Cereal Sci. 2007, 46, 207-219.
15. Dykes, L.; Rooney, L. W. Phenolic compounds in cereal grains and their health benefits. Cereal Food World 2007, 52 (3), 105-111.
16. Bratt, K.; Sunnerheim, K.; Bryngelsson, S.; Fagerlund, A.; Engman, L.; Andersson, R. E.; Dimberg, L. H. Avenanthramides in oats (Avena sativa L.) and structure-antioxidant activity relationships. J. Agric. Food Chem. 2003, 51, 594-600.
17. Bryngelsson, S.; Mannerstedt-Fogelfors, B.; Kamal-Eldin, A.; Andersson, R.; Dimberg, L. H. Lipids and antioxidants in groats and hulls of Swedish oats (Avena sativa L). J. Sci. Food Agric 2002, 82, 606-614.
18. Castellani, M. L.; Shaik, Y. B.; et al. Role of flavonoids and vitamins in cancer. Riv. Biol.-Biol. Forum 2007, 100 (1), 39-54.
19. Graf, B. A.; Milbury, P. E.; Blumberg, J. B. Flavonols, flavones, flavanones, and human health: Epidemiological evidence. J. Med. Food 2005, 8 (3), 281-290.
20. Chung, K.-T.; Wong, T. Y.; Wei, C.-I.; Huang, Y.-W.; Lin, Y. Tannins and Human Health: A Review. Crit. Rev. Food Sei. Nutr. 1998, 38, 421-464.
21. (21) Zielinski, H.; Kozlowska, H.; Lewczuk, B. Bioactive compounds in the cereal grains before and after hydrothermal processing. Innovative Food Sci. Emerging Technol. 2001, 2, 159-169. (Pubitemid 33632513)
22. (22) Blondeau, N.; Widmann, C.; Lazdunski, M.; Heurteaux, C. Activation of the nuclear factor-kappa B is a key event in brain tolerance. J. Neurosci. 2001, 21 (13), 4668-4677. (Pubitemid 32565625)
23. Zhang, J.; Ping, P. P.; Vondriska, T. M.; Tang, X. L.; Wang, G. W.; Cardwell, E. M.; Bolli, R. Cardioprotection involves activation of NF-kappa B via PKC-dependent tyrosine and serine phosphorylation of I kappa B-alpha. Am, J., Physiol.: Heart Circ. Physiol. 2003, 285 (A), H1753-H1758.
24. (24) Neurath, M. F.; Becker, C.; Barbulescu, K. Role of NF-kappa B in immune and inflammatory responses in the gut. Gut 1998, 43 (6), 856-860. (Pubitemid 28539668)
25. (25) Escarcega, R. O.; Fuentes-Alexandro, S.; Garcia-Carrasco, M.; Gatica, A.; Zamora, A. The transcription factor nuclear factorkappa B and cancer. Clin. Oncol. 2007, 19 (2), 154-161. (Pubitemid 46172840)
26. Li, Y. X.; Glauert, H. P.; Spear, B. T. Activation of nuclear factorkappa B by the peroxisome proliferator ciprofibrate in H4IIEC3 rat hepatoma cells and its inhibition by the antioxidants N-acetylcysteine and vitamin E. Biochem. Pharmacol. 2000, 59 (A), 427-434.
27. Ma, Q.; Kinneer, K.; Ye, J. P.; Chen, B. J. Inhibition of nuclear factor kappa B by phenolic antioxidants: Interplay between antioxidant signaling and inflammatory cytokine expression. Mol. Pharmacol. 2003, 64 (2), 211-219.
28. (28) Ekstrand-Hammarstrom, B.; Osterlund, C.; Lilliehook, B.; Bucht, A. Vitamin E down-modulates mitogen-activated protein kinases, nuclear factor-kappa B and inflammatory responses in lung epithelial cells. Clin, Exp. Immunol. 2007, 147 (2), 359-369. (Pubitemid 46096015)
29. Minsavage, G. D.; Dillman, J. F.III. Bifunctional alkylating agentinduced p53 and nonclassical nuclear factor kappa B responses and cell death are altered by caffeic acid phenethyl ester: A potential role for antioxidant/electrophilic response-element signalling. J. Pharm. Exp. 2007, 321 (1), 202-212.
30. (30) Austenaa, L. M. I.; Carlsen, H.; Ertesvag, A.; Alexander, G.; Blomhoff, H. K.; Blomhoff, R. Vitamin A status significantly alters nuclear factor-kappa B activity assessed by in vivo imaging. FASEB J. 2004, 18 (9), 1255-1257. (Pubitemid 39561568)
31. Benzie, I. F. F.; Strain, J. J. Ferric reducing antioxidant power assay: Direct measure of total antioxidant activity of biological fluids and modified version for simultaneous measurement of total antioxidant power and ascorbic acid concentration. Methods Enzymol. 1999, 299, 15-27.
32. Papagiannopoulos, M.; Wollseifen, H. R.; Mellenthin, A.; Haber, B.; Galensa, R. Identification and quantification of polyphenols in carob fruits (Ceratonia siliqua L.) and derived products by HPLC- UV-ESI/MSII. J. Agric. Food Chem. 2004, 52, 3784-3791.
33. (33) Wang, S. Y.; Feng, R.; Lu, Y.; Bowman, L.; Ding, M. Inhibitory Effect on Activator Protein-1, Nuclear Factor-KappaB, and Cell Transformation by Extracts of Strawberries (Fragaria x ananassa Duch.). J. Agric. Food Chem. 2005, 53, 4187-4193. (Pubitemid 40936782)
34. Wang, S. Y.; Feng, R.; Lu, Y.; Bowman, L.; Penhallegon, R.; Ding, M.; Lu, Y. Antioxidant Activity in Lingonberries (Vaccinium vitisidaea L.) and Its Inhibitory Effect on Activator Protein-1, Nuclear Factor-B, and Mitogen-Activated Protein Kinases Activation J. Agric. Food - 2005, 53, 3156-3166.
35. (35) Paur, I.; Austenaa, L. M.; Blomhoff, R. Extracts of dietary plants are efficient modulators of nuclear factor kappa B. Food Chem. Toxicol. 2008, 46 (4), 1288-1297. (Pubitemid 351258206)
36. Garcia-Conesa, M. T.; Plumb, G. W.; Waldron, K. W.; Ralph, J.; Williamson, G. Ferulic acid dehydromers from wheat bran: isolation, purification and antioxidant properties of 8-o-4-diferulic acid. Redox Ren. 1997, 3 (5/6), 319-323.
37. Onyeneho, S. N.; Hettiarachchy, N. S. Antioxidant activity of durum wheat bran. J. Agric. Food Chem. 1992, 40, 1496-1500.
38. (38) Gilmore, T. D.; Herscovitch, M. Inhibitors of NF-KB signalling: 785 and counting. Oncogene 2006, 25, 6887-6899. (Pubitemid 44657858)
39. Lampronti, I.; Khan, M. T. H.; et al. Inhibitory effects of Bangladeshi medicinal plant extracts on interactions between transcription factors and target DNA sequences. eCAM 2008, 5 (3), 303-312.
40. Jeong, W.-S.; Kim, I.-W.; Hu, R.; Kong, A. T. Modulatory properties of various natural chemopreventive agents on the activation of NF-kB signaling pathway. Pharm. Res. 2004, 21, 661-670.
41. McEleny, K.; Coffey, R.; Morrissey, C.; Fitzpatrick, J. M.; Watson, R. W. G. Caffeic acid phenethyl ester-induced PC-3 cell apoptosis os cascade-dependent and mediated through the loss of inhibitors of apoptosis proteins. BJU Int. 2004, 94, 402-406.
42. Mouria, M.; Gukovskaya, A. S.; Jung, Y.; Buechler, P.; Hines, O. J.; Reber, H. A.; Pandol, S. J. Food-derived polyphenols inhibit cancer growth through mitochondrial cytochrom C release and apoptosis. int. J. Cancer 2002, 95, 761-769.
43. Karin, M; Cao, Y; Greten, F. R.; Li, Z. W. NF-kappaB in cancer: from innocent bystander to major culprit. Nat., Rev, Cancer 2002, 2 (4), 301-310
44. Valen, G; Yan, Z. Q.; Hansson, G.. K. Nuclear factor kappa-B and the heart. J. Am, Coll. Cardiol. 2001, 38 (2), 307-314.
45. (45) Mattson, M. P.; Camandola, S. NF-kappaB in neuronal plasticity and neurodegenerative disorders. J. Clin, Invest. 2001, 107 (3), 247-254 (Pubitemid 32162153)
46. Feldmann, M; Andreakos, E; Smith, C; Bondeson, J; Yoshimura, S; Kiriakidis, S Is NF-kappaB a useful therapeutic target in rheumatoid arthritis? Ann. Rheum. Dis. 2002, 61, ii13-ii18.
47. Christman, J. W.; Sadikot, R. T.; Blackwell, T. S. The role of nuclear factor-kappa B in pulmonary diseases. Chest 2000, 117 (5), 1482-1487
48. (48) Neurath, M. F.; Becker, C.; Barbulescu, K. Role of NF-kappaB in immune and inflammatory responses in the gut. Gut 1998, 43 (6), 856-860 (Pubitemid 28539668)