Production of L-DOPA and dopamine in recombinant bacteria bearing the Vitreoscilla hemoglobin gene

Biotechnology Journal

Volumn 4, Issue 7, 2009, Pages 1077-1088

  Kurt, Asli Giray ^a   Aytan, Emel ^a   Ozer, Ufuk ^a   Ates, Burhan ^a   Geckil, Hikmet ^a  

^a INONU UNIVERSITY   (Turkey)

Author keywords

Dopamine; Erwinia herbicola; L DOPA; Tyrosine phenol lyase; Vitreoscilla hemoglobin

Indexed keywords

DOPAMINE; ERWINIA HERBICOLA; L-DOPA; TYROSINE PHENOL-LYASE; VITREOSCILLA HEMOGLOBIN;

AMINO ACIDS; BACTERIOLOGY; BEARINGS (STRUCTURAL); HEMOGLOBIN; PHENOLS;

BRAIN;

DOPAMINE; HEMOGLOBIN; LEVODOPA; TYROSINE; TYROSINE PHENOL LYASE;

ARTICLE; BACTERIAL CELL; BACTERIAL METABOLISM; BACTERIAL STRAIN; CELL GROWTH; CITROBACTER FREUNDII; CONTROLLED STUDY; CULTURE MEDIUM; CYTOPLASM; ENZYME ACTIVITY; NONHUMAN; PANTOEA AGGLOMERANS; PRIORITY JOURNAL; VITREOSCILLA;

BACTERIAL PROTEINS; CITROBACTER FREUNDII; DOPAMINE; ERWINIA; HEMEPROTEINS; LEVODOPA; RECOMBINANT PROTEINS; TRUNCATED HEMOGLOBINS; TYROSINE; TYROSINE PHENOL-LYASE;

CITROBACTER FREUNDII; PANTOEA AGGLOMERANS; VITREOSCILLA;

EID: 70350241260     PISSN: 18606768     EISSN: 18607314     Source Type: Journal    
DOI: 10.1002/biot.200900130     Document Type: Article

References (91)

1. Dougan, D., Wade, D., Mearrick, P., Effects of L-DOPA metabolites at a dopamine receptor suggest a basis for "onoff" effect in Parkinson's disease. Nature 1975, 254, 70.
2. Nadjar, A., Gerfen, C.R., Bezard, E., Priming for L-DOPA-induced dyskinesia in Parkinson's disease:A feature inherent to the treatment or the disease? Prog. Neurobiol. 2009, 87, 1-9.
3. Koyanagi, T., Katayama, T., Suzuki, H., Nakazawa, H. et al., Effective production of 3,4-dihydroxyphenyl-l-alanine (L-DOPA) with Erwinia herbicola cells carrying a mutant transcriptional regulator TyrR. J. Biotechnol. 2005, 115, 303-306.
4. Katayama, T., Suzuki, H., Koyanagi, T., Kumagai, H., Cloning and random mutagenesis of the Erwinia herbicola tyrR gene for high-level expression of tyrosine phenol-lyase. Appl. Environ. Microbiol. 2000, 66, 4764-4771.
5. Kumagai, H., Amino acid production, in: Dworkin, M., Falkow, F., Rosenberg, E., Schleifer, K.-H., Stackebrandt, E. (Eds.), The Prokaryotes, Vol 1, Springer, Berlin 2006, pp. 758-759.
6. Lütke-Eversloh,T., Santos, C. N. S., Stephanopoulos, G., Perspectives of biotechnological production of L-tyrosine and its applications. Appl. Microbiol. Biotechnol. 2007, 77, 751-762.
7. Chandel, M., Azmi, W., Optimization of process parameters for the production of tyrosine phenol-lyase by Citrobacter freundii MTCC 2424. Bioresour. Technol. 2009, 100, 1840-1846.
8. Park, H., Lee, J., Kim, H., Production of L-DOPA (3,4-dihydroxyphenyl-L-alanine) from benzene by using a hybrid pathway. Biotech. Bioeng. 1997, 58, 339-343.
9. Lee, S., Hong, S., Sung, M., Development of an enzymatic system for the production of dopamine from catechol, pyruvate, and ammonia. Enzyme Microb. Technol. 1999, 25, 298-302.
10. Kruk, Z. L., Pycock, C. J., Dopamine, in: Neurotransmitters and drugs, 3rd edn. St. Edmundsbury Press, Suffolk 1991, pp. 87-115.
11. Bailey, J. E.,Toward a science of metabolic engineering. Science 1991, 252, 1668-1675.
12. Çakar, Z. P., Metabolic and evolutionary engineering research in Turkey and beyond. Biotechnol. J. 2009, 4, DOI 10.1002/ biot.200800332
13. Wakabayashi, S., Matsubara, H., Webster, D. A., Primary sequence of a dimeric bacterial haemoglobin from Vitreoscilla. Nature 1986, 322, 481-483.
14. Khosla, C., Bailey, J. E., The Vitreoscilla hemoglobin gene, molecular cloning, nucleotide sequence and genetic expression in Escherichia coli. Mol. Gen. Genet. 1988, 214, 158-161.
15. Khosla, C., Bailey, J. E., Characterization of the oxygen-dependent promoter of the Vitreoscilla hemoglobin gene in Escherichia coli. J. Bacteriol. 1989, 171, 5995-6004.
16. Kroneck, P. M., Jakob, W., Webster, D. A., DeMaio, R., Studies on the bacterial hemoglobin from Vitreoscilla. Redox properties and spectroscopic characterization of the different forms of the hemoprotein. Biol. Met. 1991, 4, 119-125.
17. Liu, S. C., Liu, Y. X., Webster, D. A., Stark, B. C., Sequence of the region downstream of the Vitreoscilla hemoglobin gene: vgb is not part of a multigene operon. Appl. Microbiol. Biotechnol. 1994, 42, 304-308.
18. Tarricone, C., Galizzi, A., Coda, A., Ascenzi, P., Bolognesi, M., Unusual structure of the oxygen-binding site in the dimeric bacterial hemoglobin from Vitreoscilla sp. Structure 1997, 5, 497-507.
19. Tarricone, C., Calogero, S., Galizzi, A., Coda, A. et al., Expression, purification, crystallization, and preliminary X-ray diffraction analysis of the homodimeric bacterial hemoglobin from Vitreoscilla stercoraria. Proteins Struct. Func. Genet. 1997, 27, 154-156.
20. Pendse, G. J., Bailey, J. E., Effect of Vitreoscilla hemoglobin expression on growth and specific tissue-plasminogen activator productivity in recombinant Chinese-hamster ovary cells. Biotechnol. Bioeng. 1994, 44, 1367-1370.
21. Holmberg, N., Lilius, G., Bailey, J.E., Bulow, L., Transgenic tobacco expressing Vitreoscilla hemoglobin exhibits enhanced growth and altered metabolite production. Nat. Biotechnol. 1997, 15, 244-247.
22. Farres, J., Kallio, P. T., Improved cell growth in tobacco suspension cultures expressing Vitreoscilla hemoglobin. Biotechnol. Prog. 2002, 18, 229-233.
23. Wilhelmson, A., Kallio, P.T., Oksman-Caldentey, K.M., Nuutila, A. M., Expression of Vitreoscilla hemoglobin enhances growth of Hyoscyamus muticus hairy root cultures. Planta Med. 2005, 71, 48-53.
24. Li, X., Peng, R. H., Fan, H. Q., Xiong, A. S. et al., Vitreoscilla hemoglobin overexpression increases submergence tolerance in cabbage. Plant Cell Rep. 2005, 23, 710-715.
25. Wilhelmson, A., Hakkinen, S. T., Kallio, P. T., Oksman-Caldentey, K. M. et al., Heterologous expression of Vitreoscilla hemoglobin (VHb) and cultivation conditions affect the alkaloid profile of Hyoscyamus muticus hairy roots. Biotechnol. Prog. 2006, 22, 350-358.
26. Zelasco, S., Reggi, S., Calligari, P., Balestrazzi, A. et al., Expression of the Vitreoscilla hemoglobin (VHb)-encoding gene in transgenic white poplar: Plant growth and biomass production, biochemical characterization and cell survival under submergence, oxidative and nitrosative stress conditions. Mol. Breed. 2006, 17, 201-216.
27. Jokipii-Lukkari, S., Frey, A. D., Kallio, P. T., Häggman, H., Intrinsic non-symbiotic and truncated haemoglobins and heterologous Vitreoscilla haemoglobin expression in plants. J. Exp. Bot. 2009, 60, 409-422.
28. Bhave, S. L., Chattoo, B. B., Expression of Vitreoscilla hemoglobin improves growth and levels of extracellular enzyme in Yarrowia lipolytica. Biotechnol. Bioeng. 2003, 84, 658-666.
29. Wu, J. M., Hsu, T. A., Lee, C. K., Expression of the gene coding for bacterial hemoglobin improves beta-galactosidase production in a recombinant Pichia pastoris. Biotechnol. Lett. 2003, 25, 1457-1462.
30. Ruohonen, L., Aristidou, A., Frey, A.D., Penttila, M. et al., Expression of Vitreoscilla hemoglobin improves the metabolism of xylose in recombinant yeast Saccharomyces cerevisiae under low oxygen conditions. Enzyme Microb. Technol. 2006, 39, 6-14.
31. Suthar, D. H., Chattoo, B. B., Expression of Vitreoscilla hemoglobin enhances growth and levels of alpha-amylase in Schwanniomyces occidentalis. Appl. Microbiol. Biotechnol. 2006, 72, 94-102.
32. Chen, H.X., Chu, J., Zhang, S.L., Zhuang, Y.P. et al., Intracellular expression of Vitreoscilla hemoglobin improves S-adenosylmethionine production in a recombinant Pichia pastoris. Appl. Microbiol. Biotechnol. 2007, 74, 1205-1212.
33. Hofmann, G., Diano, A., Nielsen, J., Recombinant bacterial hemoglobin alters metabolism of Aspergillus niger. Metab. Eng. 2009, 11, 8-12.
34. Liu, S.C., Webster, D.A., Stark, B.C., Cloning and expression of the Vitreoscilla hemoglobin gene in pseudomonads: Effects on cell growth. Appl. Microbiol. Biotechnol. 1995, 44, 419-424.
35. 2. Biotechnol. Lett. 1996, 18, 695-700.
36. Tsai, P.S., Hatzimanikatis, V., Bailey, J.E., Effect of Vitreoscilla hemoglobin dosage on microaerobic Escherichia coli carbon and energy metabolism. Biotechnol. Bioeng. 1996, 49, 139-150.
37. Liu, S. C., Webster, D. A., Stark, B. C., Genetic engineering to contain the Vitreoscilla hemoglobin gene enhances degradation of benzoic acid by Xanthomonas maltophilia. Biotechnol. Bioeng. 1996, 49, 101-105.
38. Wie, M. L., Webster, D. A., Stark, B. C., Genetic engineering of Serratia marcescens with bacterial hemoglobin gene: Effects on growth, oxygen utilization, and cell size. Biotechnol. Bioeng. 1998, 57, 477-483.
39. Wie, M.L., Webster, D.A., Stark, B.C., Metabolic engineering of Serratia marcescens with the bacterial hemoglobin gene: Alterations in fermentation pathways. Biotechnol. Bioeng. 1998, 59, 640-646.
40. Khosla, C., Bailey, J. E., Heterologous expression of a bacterial haemoglobin improves the growth properties of recombinant Escherichia coli. Nature 1988, 331, 633-635.
41. - recombinant Escherichia coli: Some observations. Biotechnol. Prog. 1999, 15, 640-645.
42. Aydin, S., Webster, D.A., Stark, B.C., Nitrite inhibition of Vitreoscilla hemoglobin (VHb) in recombinant E. coli: Direct evidence that VHb enhances recombinant protein production. Biotechnol. Prog. 2000, 16, 917-921.
43. Fish, P. A., Webster, D. A., Stark, B. C., Vitreoscilla hemoglobin enhances the first step in 2,4-dinitrotoluene degradation in vitro and at low aeration in vivo. J. Mol. Catal. B Enzym. 2000, 9, 75-82.
44. Geckil, H., Stark, B. C., Webster, D. A., Cell growth and oxygen uptake of Escherichia coli and Pseudomonas aeruginosa are differently affected by the genetically engineered Vitreoscilla hemoglobin gene. J. Biotechnol. 2001, 85, 57-66.
45. Chung, J. W., Webster, D. A., Pagilla, K. R., Stark, B. C., Chromosomal integration of the Vitreoscilla hemoglobin gene in Burkholderia and Pseudomonas for the purpose of producing stable engineered strains with enhanced bioremediating ability. J. Ind. Microbiol. Biotechnol. 2001, 27, 27-33.
46. Roos, V., Andersson, C.I.J., Arfvidsson, C., Wahlund, K.G. et al., Expression of double Vitreoscilla hemoglobin enhances growth and alters ribosome and tRNA levels in Escherichia coli. Biotechnol. Prog. 2002, 18, 652-656.
47. Kaur, R., Pathania, R., Sharma, V., Mande, S. C. et al., Chimeric Vitreoscilla hemoglobin (VHb) carrying a flavoreductase domain relieves nitrosative stress in Escherichia coli: New insight into the functional role of VHb. Appl. Environ. Microbiol. 2002, 68, 152-160.
48. Yu, H. M., Shi, Y., Zhang, Y. P., Yang, S. L. et al., Effect of Vitreoscilla hemoglobin biosynthesis in Escherichia coli on production of poly(beta-hydroxybutyrate) and fermentative parameters. FEMS Microbiol. Lett. 2002, 214, 223-227.
49. Kang, D. G., Kim, J.Y. H., Cha, H. J., Enhanced detoxification of organophosphates using recombinant Escherichia coli with co-expression of organophosphorus hydrolase and bacterial hemoglobin. Biotechnol. Lett. 2002, 24, 879-883.
50. Lin, J. M., Stark, B. C., Webster, D. A., Effects of Vitreoscilla hemoglobin on the 2,4-dinitrotoluene (2,4-DNT) dioxygenase activity of Burkholderia and on 2,4-DNT degradation in two-phase bioreactors. J. Ind. Microbiol. Biotechnol. 2003, 30, 362-368.
51. Urgun-Demirtas, M., Pagilla, K. R., Stark, B. C., Webster, D. A., Biodegradation of 2-chlorobenzoate by recombinant Burkholderia cepacia expressing Vitreoscilla hemoglobin under variable levels of oxygen availability. Biodegradation 2003, 14, 357-365.
52. Geckil, H., Gencer, S., Kahraman, H., Erenler, S. O., Genetic engineering of Enterobacter aerogenes with Vitreoscilla hemoglobin gene: Cell growth, survival, and antioxidant enzyme status under oxidative stress. Res. Microbiol. 2003, 154, 425-431.
53. Geckil, H., Barak, Z., Chipman, D. M., Erenler, S. O. et al., Enhanced production of acetoin and butanediol in recombinant Enterobacter aerogenes carrying Vitreoscilla hemoglobin gene. Bioprocess Biosyst. Eng. 2004, 26, 325-330.
54. Geckil, H., Gencer, S., Uckun, M., Vitreoscilla hemoglobin expressing Enterobacter aerogenes and Pseudomonas aeruginosa respond differently to carbon catabolite and oxygen repression for production of L-asparaginase:An enzyme used in cancer therapy. Enzyme Microb.Technol. 2004, 35, 182-189.
55. Erenler, S. O., Gencer, S., Geckil, H., Stark, B. C. et al., Cloning and expression of the Vitreoscilla hemoglobin gene in Enterobacter aerogenes: Effect on cell growth an oxygen uptake. Appl. Biochem. Microbiol. 2004, 40, 241-248.
56. Geckil, H., Gencer, S., Production of L-asparaginase in Enterobacter aerogenes expressing Vitreoscilla hemoglobin for efficient oxygen uptake. Appl. Microbiol. Biotechnol. 2004, 63, 691-697.
57. Erenler, S. O., Gencer, S., Geckil, H., Stark, B. C. et al., Cloning and expression of the Vitreoscilla hemoglobin gene in Enterobacter aerogenes: Effect on cell growth an oxygen uptake. Appl. Biochem. Microbiol. 2004, 40, 241-248.
58. Kim, Y. K., Kang, D. G., Choi, S. S., Kim, J. H. et al., Co-expression of bacterial hemoglobin overrides high glucose-induced repression of foreign protein expression in Escherichia coli W3110. Biotechnol. Lett. 2004, 26, 1173-1178.
59. Johnvesly, B., Kang, D. G., Choi, S. S., Kim, J. H. et al., Comparative production of green fluorescent protein under coexpression of bacterial hemoglobin in Escherichia coli W3110 using different culture scales. Biotechnol. Bioprocess Eng. 2004, 9, 274-277.
60. So, J. H., Webster, D. A., Stark, B. C., Pagilla, K. R., Enhancement of 2,4-dinitrotoluene biodegradation by Burkholderia sp in sand bioreactors using bacterial hemoglobin technology. Biodegradation 2004, 15, 161-171.
61. Kim, Y., Webster, D. A., Stark, B. C., Improvement of bioremediation by Pseudomonas and Burkholderia by mutants of the Vitreoscilla hemoglobin gene (vgb) integrated into their chromosomes. J. Ind. Microbiol. Biotechnol. 2005, 32, 148-154.
62. Kahraman, H., Geckil, H., Degradation of benzene, toluene and xylene by Pseudomonas aeruginosa engineered with the Vitreoscilla hemoglobin gene. Eng. Life Sci. 2005, 5, 363-368.
63. Geckil, H., Gencer, S., Ates, B., Ozer, U. et al., Effect of Vitreoscilla hemoglobin on production of a chemotherapeutic enzyme, L-asparaginase, by Pseudomonas aeruginosa. Biotechnol. J. 2006, 1, 203-208.
64. Khleifat, K. M., Abboud, M. M., Al-Mustafa, A. H., Al-Sharafa, K. Y., Effects of carbon source and Vitreoscilla hemoglobin (VHb) on the production of beta-galactosidase in Enterobacter aerogenes. Curr. Microbiol. 2006, 53, 277-281.
65. Dogan, I., Pagilla, K. R., Webster, D. A., Stark, B. C., Expression of Vitreoscilla hemoglobin in Gordonia amarae enhances biosurfactant production. J. Ind. Microbiol. Biotechnol. 2006, 33, 693-700.
66. Feng, L., Chen, S. W., Sun, M., Yu, Z. N., Expression of Vitreoscilla hemoglobin in Bacillus thuringiensis improve the cell density and insecticidal crystal proteins yield. Appl. Microbiol. Biotechnol. 2007, 74, 390-397.
67. 2 tension maximizes bacterial cellulose pellicle production. J. Biotechnol. 2007, 132, 38-43.
68. Tao, L., Sedkova, N., Yao, H., Ye, R.W. et al., Expression of bacterial hemoglobin genes to improve astaxanthin production in a methanotrophic bacterium Methylomonas sp. Appl. Microbiol. Biotechnol. 2007, 74, 625-633.
69. Chien, L. J., Lee, C. K., Enhanced hyaluronic acid production in Bacillus subtilis by coexpressing bacterial hemoglobin. Biotechnol. Prog. 2007, 23, 1017-1022.
70. Liu, Q., Zhang, J., Wie, X. X., Ouyang, S. P. et al., Microbial production of L-glutamate and L-glutamine by recombinant Corynebacterium glutamicum harboring Vitreoscilla hemoglobin gene vgb. Appl. Microbiol. Biotechnol. 2008, 77, 1297-1304.
71. Priscila, G., Fernandez, F. J., Absalon, A. E., Suarez, M. D. et al., Expression of the bacterial hemoglobin gene from Vitreoscilla stercoraria increases rifamycin B production in Amycolatopsis mediterranei. J. Biosci. Bioeng. 2008, 106, 493-497.
72. Kim, D., Hwang, D. S., Kang, D. G., Kim, J. Y. H. et al., Enhancement of mussel adhesive protein production in Escherichia coli by co-expression of bacterial hemoglobin. Biotechnol. Prog. 2008, 24, 663-666.
73. Clark, D.P., The number of anaerobically regulated genes in Escherichia coli. FEMS Microbiol. Lett. 2006, 24, 251-254.
74. Salmon, K., Hung, S. P., Mekjian, K., Baldi, P. et al., Global gene expression profiling in Escherichia coli K12: The effects of oxygen availability and FNR. J. Biol. Chem. 2003, 278, 29837-29855.
75. Salmon, K. A., Hung, S. P., Steffen, N. R., Krupp, R. et al., Global gene expression profiling in Escherichia coli K-12: Effects of oxygen availability and ArcA. J. Biol. Chem. 2005, 280, 15084-15096.
76. Joshi M, Dikshit KL., Oxygen dependent regulation of Vitreoscilla globin gene: Evidence for positive regulation by FNR. Biochem. Biophys. Res. Commun. 1994, 202, 535-544.
77. Tsai, P. S., Kallio, P. T., Bailey, J. E., Fnr, a global transcriptional regulator of Escherichia coli, activates the Vitreoscilla hemoglobin (VHb) promoter and intracellular VHb expression increases cytochrome d promoter activity. Biotechnol. Prog. 1995, 11, 288-293.
78. Frey A. D., Koskenkorva, T., Kallio, P. T., Vitreoscilla hemoglobin promoter is not responsive to nitrosative and oxidative stress in Escherichia coli. FEMS Microbiol. Lett. 2003, 224, 127-132.
79. Yang, J., Webster, D. A., Stark, B. C., ArcA works with Fnr as a positive regulator of Vitreoscilla (bacterial) hemoglobin gene expression in Escherichia coli. Microbiol. Res. 2005, 160, 405-415.
80. Khosravi, M., Webster, D.A., Stark, B.C., Presence of the bacterial hemoglobin gene improves α-amylase production of a recombinant Escherichia coli strain. Plasmid 1990, 24, 190-194.
81. Birnboim H. C., Doly J., A rapid alkaline extraction procedure for screening recombinant plasmid DNA. Nucleic Acids Res. 1979, 7, 1513-1523.
82. Ausubel F. M., Brent R., Kingston R. E., Moore D. D. et al. (Eds.), Current Protocols in Molecular Biology, John Wiley & Sons, New York 2005, 1.6.1-1.6.10.
83. Wriston, J. C. Jr., L-Asparaginase. Methods Enzymol. 1970, 17, 732-742.
84. Bradford, M.M., A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 7, 248-254.
85. Martinez, A., York, S. W., Yomano, L. P., Pineda, V. L. et al., Biosynthetic burden and plasmid burden limit expression of chromosomally integrated heterologous genes (pdc, adhB) in Escherichia coli. Biotechnol. Prog. 1999, 15, 891-897.
86. Ricci, J. C. D., Hernandez, M. E., Plasmid effects on Escherichia coli metabolism. Crit. Rev. Biotechnol. 2000, 20, 79-108.
87. Lyte, M., Induction of Gram-negative bacterial growth by neurochemical containing banana (Musa × paradisiaca) extracts. FEMS Microbiol. Lett. 1997, 154, 245-250.
88. Kinney, K.S., Austin, C.E., Morton, D.S. et al., Catecholamine enhancement of Aeromonas hydrophila growth. Microb. Pathog. 1999, 26, 85-91.
89. Belay, T., Sonnenfeld, G., Differential effects of catecholamines on in vitro growth of pathogenic bacteria. Life Sci. 2002, 71, 447-456.
90. Kircher, M., White biotechnology: Ready to partner and invest in. Biotechnol. J. 2006, 1, 787-794.
91. Stark, B. C., Urgun-Demirtas, M., Pagilla, K. R., Role of hemoglobin in improving biodegradation of aromatic contaminants under hypoxic conditions. J. Mol. Microbiol. Biotechnol. 2008, 15, 181-189.