Effect of Vitreoscilla hemoglobin dosage on microaerobic Escherichia coli carbon and energy metabolism

Biotechnology and Bioengineering

Volumn 49, Issue 2, 1996, Pages 139-150

  Tsai, Philip S ^a   Hatzimanikatis, Vassily ^a   Bailey, James E ^a  

^a ETH ZURICH   (Switzerland)

Author keywords

dose response; flux analysis; microaerobic metabolism; Vitreoscilla hemoglobin

Indexed keywords

CARBON; COLIFORM BACTERIA; FERMENTATION; GROWTH KINETICS; HEMOGLOBIN; METABOLISM; PHYSIOLOGY;

ENERGY METABOLISM; ESCHERICHIA COLI; MICROAEROBIC METABOLISM; VITREOSCILLA HEMOGLOBIN;

BIOTECHNOLOGY;

CARBON; GLUCOSE; HEMOGLOBIN; ISOPROPYL THIOGALACTOSIDE; OXYGEN;

AEROBIC METABOLISM; ARTICLE; BACTERIAL GROWTH; BACTERIAL METABOLISM; CELL RESPIRATION; ENERGY METABOLISM; GENE DOSAGE; GENE EXPRESSION; GLUCOSE METABOLISM; METABOLIC BALANCE; NONHUMAN;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; VITREOSCILLA;

EID: 0030051960     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0290(19960120)49:2<139::AID-BIT3>3.0.CO;2-R     Document Type: Article

References (36)

1. Bachmann, B. J. 1987. Derivations and genotypes of some mutant derivatives of Escherichia coli K-12. pp. 1191-1219. In: J. L. Ingraham, K. B. Low, B. Magasanik, M. Schaechter, and H. E. Umbarger (eds.), Escherichia coli and Salmonella typhimurium: Cellular and molecular biology. American Society for Microbiology, Washington, D.C.
2. Bergmeyer, H. U. 1985. In: Methods of enzymatic analysis, vol. VI. VCH Publishers, Deerfield Beach, FL.
3. Bergmeyer, H. U. 1985. In: Methods of enzymatic analysis, vol. VII. VCH Publishers, Deerfield Beach, FL.
4. Bolivar, F., Rodriguez, R. L., Greene, P. J., Betlach, M. C., Heyneker, H. L., Boyer, H. W., Crosa, J. H., Falkow, S. 1977. Construction and characterization of new cloning vehicles. II. A multipurpose cloning system. Gene 2: 95-113.
5. 31P NMR and saturation transfer study. Biotechnol. Prog. 10: 360-364.
6. Delacruz, N., Payne, G. F., Smith, J. M., Coppella, S. J. 1992. Bioprocess development to improve foreign protein production from recombinant Streptomyces. Biotechnol. Biotechnol. 8: 307-315.
7. DeModena, J. A., Gutierrez, S., Velasco, J., Fernandez, F. J., Fachini, R. A., Galazzo, J. L., Hughes, D. E , Martin, J. F. 1993. The production of cephalosporin C by Acremonium chrysogenum is improved by the intracellular expression of a bacterial hemoglobin. Bio/Technology 11: 926-929.
8. Galazzo, J., Bailey, J. E. 1990. Fermentation pathway kinetics and metabolic flux control in suspended and immobilized Saccharomyces cerevisiae. Enz. Microb. Technol. 12: 162-172
9. Gottschalk, G. 1986. Bacterial metabolism, 2nd edition. Springer-Verlag, New York.
10. Hart, R. A., Bailey, J. E. 1991. Purification and aqueous 2-phase partitioning properties of recombinant Vitreoscilla hemoglobin. Enz. Microb. Technol. 13: 788-795.
11. Holms, W. H. 1986. The central metabolic pathways of Escherichia coli: Relationship between flux and control at a branch point, efficiency of conversion to biomass, and excretion of acetate. pp. 69-105. In. Current topics in cellular regulation, vol. 28. Academic New York.
12. Iuchi, S., Lin, E. C. C. 1991. Adaptation of Escherichia coli to respiratory conditions: Regulation of gene expression. Cell 66: 5-7.
13. Jensen, P. R, Michelsen, O. 1992. Carbon and energy metabolism of atp mutants of Escherichia coli. J. Bacteriol. 174: 7635-7641.
14. Kallio, P. T., Kim, D. J., Tsai, P. S., Bailey, J. E. 1994. Intracellular expression of Vitreoscilla hemoglobin alters Escherichia coli energy metabolism under oxygen-limited conditions. Eur. J. Biochem. 219: 201-208.
15. Khosla, C., Bailey, J. E. 1988. Heterologous expression of a bacterial haemoglobin improves the growth properties of recombinant Escherichia coli. Nature 331: 633-635.
16. Khosla, C., Bailey, J E. 1989. Evidence for partial export of Vitreoscilla hemoglobin into the periplasmic space in Escherichia coli. J. Mol. Biol. 210: 79-90.
17. Khosla, C., Curtis, J. E., DeModena, J., Rinas, R., Bailey, J. E. 1990. Expression of intracellular hemoglobin improves protein synthesis in oxygen-limited Escherichia coli. Bio/Technol. 8: 849-853.
18. Khosravi, M., Webster, D. A., Start, B. C. 1990. Presence of bacterial hemoglobin gene improves α-amylase production of a recombinant Escherichia coli strain. Plasmid 24: 190-194.
19. Konstantinov, K. B., Nishio, N., Seki, T., Yoshida, T. 1991. Physiologically motivated strategies for control of the fed-batch cultivation of recombinant Escherichia coli for phenylalanine production. J. Ferm. Bioeng 71: 350-355.
20. Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685.
21. Magnolo, S. K., Leenutaphong, D L., DeModena, J. A., Curtis, J. E., Bailey, J. E., Galazzo, J. L., Hughes, D. E. 1991. Actinorhodin production by Streptomyces coelicolor and growth of Streptomyces lividans are improved by the expression of a bacterial hemoglobin. Bio/Technology 9: 473-476.
22. Manfredini, R., Cavallera, V., Marini, L., Donati, G. 1983. Mixing and oxygen transfer in conventional stirred fermentors. Biotechnol. Bioeng. 25: 3115-3131.
23. Neidhardt, F. 1987. Chemical composition of Escherichia coli. pp. 4-6, In: J. L. Ingraham, K. B. Low, B. Magasanik, M. Schaechter, and H. E. Umbarger (eds.), Escherichia coli and Salmonella typhimurium. Cellular and molecular biology. American Society for Microbiology, Washington, DC.
24. Neidhardt, F. C., Ingraham, J. L., Schaechter, M. 1990. Biosynthesis and fueling. pp. 133-173. In: Physiology of the bacterial cell: A molecular approach. Sinauer Associates, Sunderland, MA.
25. O'Connor, G. M , Sanchezriera, F., Cooney, C. L. 1992. Design and evaluation of control strategies for high cell-density fermentations Biotechnol. Bioeng. 39: 293-304.
26. Onken, U., Leifke, E. 1989. Effect of total and partial pressure (oxygen and carbon dioxide) on aerobic microbial processes. Adv. Biochem. Eng. Biotechnol. 40: 137-169.
27. Oosterhuis, N. M. G., Kossen, N. W F. 1984. Dissolved oxygen concentration profiles in a production scale bioreactor. Biotechnol. Bioeng. 26: 546-555.
28. Papoutsakis, E. T., Meyer, C L. 1985. Equations and calculations of product yields and preferred pathways for butanediol and mixed-acid fermentation. Biotechnol. Bioeng. 27: 50-66.
29. Spiro, S., Guest, J. R. 1991. Adaptive responses to oxygen limitation in Escherichia coli. Trends in Biochem. Sci. 16. 310-314.
30. Stephanopoulos, G., Vallino, J. J 1991. Network rigidity and metabolic engineering in metabolic overproduction. Science 252: 1675-1681
31. Tsai, P S., Rao, G., Bailey, J. E. Improvement of Escherichia coli microaerobic oxygen metabolism by Vistreoscilla hemoglobin: New insights from NAD(P)H fluorescence and culture redox potential. Biotechnol. Bioeng.
32. Vallino, J., Stephanopoulos, G. 1990. Flux determination in cellular bioreaction network: Application to lysine fermentation. pp. 205-219. In: Frontiers in bioprocessing. CRC Press, Boca Raton, FL.
33. Vallino, J., Stephanopoulos, G. 1993. Metabolic flux distributions in Corynebacterium glutamicum during growth and lysine overproduction. Biotechnol Bioeng. 41: 633-646.
34. Varma, A., Boesch, B , Palsson, B. O. 1993. Stoichiometric interpretation of Escherichia coli glucose catabolism under various oxygenation rates Appl. Environ. Microbiol. 59: 2465-2473.
35. Varma, A., Palsson, B. O. 1994. Metabolic flux balancing: Basic concepts, scientific and practical use. Bio/Technology 12: 994-998.
36. Winston, S. E., Fuller, S. A., Hurrell, J. G. R. 1987. Western blotting pp. 10.8.1-10.8.6. In: F. M. Ausubel, R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhi (eds.), Current protocols in molecular biology. Wiley, New York.