Increases in the phosphorylation of cyclic AMP response element binding protein (CREB) and decreases in the content of calcineurin accompany thermal hyperalgesia following chronic constriction injury in rats

Pain

Volumn 99, Issue 3, 2002, Pages 493-500

  Miletic, Gordana ^a   Pankratz, Matthew T ^a   Miletic, Vjekoslav ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Chronic pain; Kinase; Nociception; Nuclear protein; Phosphatase; Primary afferents; Spinal cord injury; Synaptic plasticity

Indexed keywords

CALCINEURIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; HYPERALGESIA; MALE; NERVE COMPRESSION; NERVE LIGATION; NEUROPATHIC PAIN; NONHUMAN; PHOSPHORYLATION; POSTOPERATIVE COMPLICATION; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; SCIATIC NERVE; SPINAL CORD DORSAL HORN; SURGICAL TECHNIQUE;

ANIMALS; CALCINEURIN; CONSTRICTION, PATHOLOGIC; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DOWN-REGULATION; HYPERALGESIA; MALE; PHOSPHORYLATION; POSTERIOR HORN CELLS; RATS; RATS, SPRAGUE-DAWLEY; SCIATIC NEUROPATHY; UP-REGULATION;

EID: 0036804410     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(02)00242-7     Document Type: Article

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