Induction of spinal cord neuronal nitric oxide synthase (NOS) after formalin injection in the rat hind paw

Neuroscience Letters

Volumn 210, Issue 3, 1996, Pages 201-204

  Lam, H H D ^a,b   Hanley, D F ^a,b   Trapp, B D ^a,b   Saito, S ^a,b   Raja, S ^a,b   Dawson, T M ^a,b   Yamaguchi, H ^a,b  

^a DEPARTMENT OF PATHOLOGY   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Induction; Injury; Nitric oxide synthase; Pain; Spinal cord

Indexed keywords

FORMALDEHYDE; NITRIC OXIDE SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PAIN; PRIORITY JOURNAL; RAT; SPINAL CORD DORSAL HORN; SPINAL CORD INJURY;

EID: 0030009063     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3940(96)12702-6     Document Type: Article

References (30)

1. Bredt, D.S., Glatt, C.E., Hwang, P.M., Fotuhi, M., Dawson, T.M. and Snyder, S.H., Nitric oxide synthase protein and mRNA are discretely localized in neuronal populations of the mammalian CNS together with NADPH diaphorase, Neuron, 7 (1991) 615-624.
2. Bredt, D.S. and Snyder, S.H., Nitric oxide, a novel neuronal messenger, Neuron, 8 (1992) 3-11.
3. Coghill, R.C., Price, D.D., Hayes, R.L. and Mayer, D.J., Spatial distribution of nociceptive processing in the rat spinal cord, J. Neurophysiol., 65 (1991) 133-140.
4. Dawson, T.M., Bredt, D.S., Fotuhi, M., Hwang, P.M. and Snyder, S.H., Nitric oxide synthase and neuronal NADPH diaphorase are identical in brain and peripheral tissues. Proc. Natl. Acad. Sci. USA, 88 (1991) 7797-7801.
5. Dawson, T.M. and Dawson, V.L., Nitric oxide: actions and pathological roles, Neuroscientist, 1 (1995) 7-18.
6. Dawson, T.M. and Synder, S.H., Gases as biological messenger: nitric oxide and carbon monoxide in the brain, J. Neurosci., 14 (1994) 5202-5222.
7. Guy, E.R. and Abbott, F.V., The behavioral response to formalin in preweanling rats, Pain, 51 (1992) 81-90.
8. Haley, J.E., Dickenson, A.H. and Schachter, M., Electrophysiological evidence for a role of nitric oxide in prolonged chemical nociception in rat, Neuropharmacology, 31 (1992) 51-258.
9. Hao J-X., Xu X-J. and Wiesenfeld-Hallin, Z., Systemic N-nitro-L-arginine-ester (LNAME), inhibitor of nitric oxide synthase, relieves chronic allodynia-like symptom in rats with spinal cord lesion, Acta Physiol. Scand., 50 (1994) 457-458.
10. Hope, B.T., Michael, G.J., Knigge, K.M. and Vincent, S.R., Neuronal NADPH diaphorase is a nitric oxide synthase, Proc. Natl. Acad. Sci. USA, 88 (1991) 2811-2814.
11. Kitto, K.F., Haley, J.E. and Wilcox, G.L., Involvement of nitric oxide in spinally mediated hyperalgesia in the mouse, Neurosci. Lett., 148 (1992) 1-5.
12. Lee, J.H., Wilcox, G.L. and Beitz, A.J., Nitric oxide mediates FOS expression in the spinal cord induced by mechanical noxious stimulation, NeuroReport, 3 (1992) 841-844.
13. Mao, J., Price, D.D., Coghill, R.C., Mayer, D.J. and Hayes, R.L., Spatial patterns of spinal cord [14C] -2-deoxyglucose metabolic activity in a rat model of painful peripheral mononeuropathy, Pain, 50 (1992) 89-100.
14. Meller, S.T., Dykstra, C. and Gebhart, G.F., Production of endogenous nitric oxide and activation of soluble guanylate cyclase are required for N-methyl-D-aspartate-produced facilitation of the nociceptive tail-flick reflex, Eur. J. Pharmacol., 214 (1992) 93-96.
15. Moore, P.K., Oluyomi, A.O., Babbedge, R.C., Wallace, P. and Hart, S.L., L-NG-nitro-arginine methyl ester exhibits antinociceptive activity in the mouse, Br. J. Pharmacol., 102 (1991) 198-202.
16. Nadelhaft, I. and Booth, A.M., The location and morphology of preganglionic neurons and the distribution of visceral afferents from the rat pelvic nerve: a horseradish peroxidase study, J. Comp. Neurol., 226 (1984) 238-245.
17. Nathan, C., Nitric oxide as a secretary product of mammalian cells, FASEB J., 6 (1992) 3051-3064.
18. Nunez, R., Gross, G.H. and Sachs, B.D., Origin and central projections of rat dorsal penile nerve: possible direct projection to autonomic and somatic neurons by primary afferents of nonmuscle origin, J. Comp. Neurol., 247 (1986) 417-429.
19. Paxinos, G., The Human Nervous System, Academic Press, New York, 1990, 819 pp.
20. Rustioni, A. and Weinberg, R.J., The somatosensory system. In: A. Björklund, T. Hökfelt and L.W. Swanson (Eds.), Handbook of Chemical Neuroanatomy, Vol. 7, Elsevier, Amsterdam, 1989, pp. 219-321.
21. Saito, S., Kidd, G.J., Trapp, B.D., Dawson, T.M., Bredt, D.S., Wilson, D.A., Traystman, R.J., Snyder, S.H. and Hanley, D.F., Rat spinal cord neurons contain nitric oxide synthase, Neuroscience, 59(2) (1994) 447-456.
22. Shibata, M., Ohkubo, T., Takahashi, H. and Inoki, R., Modified formalin test: characteristic biphasic pain response, Pain, 38 (1989) 347-352.
23. Solodkin, A., Traub, R.J. and Gebhart, G.F. Unilateral hindpaw inflammation produces a bilateral increase in NADPH Diaphorase histochemical staining in the rat lumbar spinal cord, Neuroscience, 51(3) (1992) 495-499.
24. Synder, S.H. and Bredt, D.S., Biological roles of nitric oxide, Sci. Am., (1992).
25. Tjolsen, A., Berge, O.G., Hunskaar, S., Rosland, J.H. and Hole, K., The formalin test: an evaluation of the method, Pain, 51 (1992) 5-17.
26. Valtschanoff, J.G., Weinberg, R.J. and Rustioni, A., NADPH diaphorase in the spinal cord of rats, J. Comp. Neurol., 321 (1992) 209-222.
27. Verge, V.M.K., Xu, Z., Xu, X.-J., Wiesenfeld-Hallin, Z.W. and Hokfelt, T., Marked increase in nitric oxide synthase mRNA in rat dorsal root ganglia after peripheral axotomy: in situ hybridization and functional studies, Proc. Natl. Acad. Sci. USA, 89 (1992) 11617-11621.
28. Wiesenfeld-Hallin, Z., Hao, J.-X., Xu, X.-J. and Hokfelt, T., Nitric oxide mediates ongoing discargesin dorsal root ganglion cells after peripheral nerve injury, J. Neurophysiol., 70 (1993) 2250-2253.
29. Young, H.M., Furness, J.B., Shuttleworth, C.W., Bredt, D.S. and Snyder, S.H., Co-localization of nitric oxide synthase immunoreactivity and NADPH diaphorase staining in neurons of the guinea-pig intestine, Histochemistry, 97 (1992) 375-378.
30. Zhang, X., Verge, V., Wiesenfeld-Hallin, Z., Ju, G., Bradt, D., Snyder, S.H. and Hodfelt, T., Nitric oxide synthase-like immunoreactivity in lumbar dorsal root ganglia and spinal cord of rat and monkey and effect of peripheral axotomy, J. Comp. Neurol., 335 (1993) 563-575.