Spinal neurokinin3 receptors mediate thermal but not mechanical hyperalgesia via nitric oxide

Pain

Volumn 80, Issue 1-2, 1999, Pages 309-317

  Linden, David R ^a   Seybold, Virginia S ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Hyperalgesia; Neurokinin; NK3 receptor; Nociception; Rat; Spinal cord

Indexed keywords

N(G) NITROARGININE METHYL ESTER; NEUROKININ 3 RECEPTOR; NEUROKININ 3 RECEPTOR ANTAGONIST; NICOTINIC RECEPTOR BLOCKING AGENT; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; OSANETANT; SENKTIDE; SUBSTANCE P; DRUG DERIVATIVE; ENZYME INHIBITOR; NITRIC OXIDE SYNTHASE; PEPTIDE FRAGMENT; PIPERIDINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DORSAL ROOT; DRUG EFFECT; FACILITATION; FLEXOR REFLEX; HYPERALGESIA; INTRATHECAL DRUG ADMINISTRATION; MALE; NOCICEPTION; NONHUMAN; PAIN THRESHOLD; PRIORITY JOURNAL; RAT; SKIN TEMPERATURE; STIMULATION; ANIMAL; BODY EQUILIBRIUM; BODY TEMPERATURE; CYTOLOGY; DRUG ANTAGONISM; DRUG POTENTIATION; ELECTROSTIMULATION; HEAT; MOTONEURON; NEWBORN; PATHOPHYSIOLOGY; PHYSIOLOGY; SPINAL CORD; SPRAGUE DAWLEY RAT;

ANIMALS; ANIMALS, NEWBORN; BODY TEMPERATURE; ELECTRIC STIMULATION; ENZYME INHIBITORS; HEAT; HYPERALGESIA; MALE; MOTOR NEURONS; MUSCULOSKELETAL EQUILIBRIUM; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PEPTIDE FRAGMENTS; PHYSICAL STIMULATION; PIPERIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NEUROKININ-3; SPINAL CORD; SUBSTANCE P;

EID: 0032588157     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(98)00222-X     Document Type: Article

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