Evoked release of amino acids and prostanoids in spinal cords of anesthetized rats: Changes during peripheral inflammation and hyperalgesia

American Journal of Therapeutics

Volumn 3, Issue 4, 1996, Pages 268-275

  Sorkin, Linda S ^a,b   Moore, John H ^a  

^a UCSD Medical Cent Hillcrest   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

aspartate; glutamate; nitric oxide; NMDA

Indexed keywords

AMINO ACID; ASPARTIC ACID; CITRULLINE; DIZOCILPINE; GLUTAMINE; GLYCINE; KETOROLAC TROMETAMOL; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE INHIBITOR; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE INHIBITOR; PROSTANOID; THROMBOXANE B2;

ANIMAL MODEL; ANIMAL TISSUE; ARTHRITIS; ARTICLE; CONTROLLED STUDY; EVOKED SPINAL CORD RESPONSE; HYPERALGESIA; INTRATHECAL DRUG ADMINISTRATION; MALE; NERVE FIBER C; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; RAT; SCIATIC NERVE;

EID: 0029952176     PISSN: 10752765     EISSN: None     Source Type: Journal    
DOI: 10.1097/00045391-199604000-00003     Document Type: Article

References (29)

1. Lewis T: Pain. Macmillan, New York, 1942.
2. LaMotte RH, Shain CN, Simone DA, Tsai E-FP: Neurogenic hyperalgesia: psychophysical studies of underlying mechanisms. J Neurophys. 1991;66:190-211.
3. Woolf CJ, Wall PD: The relative effectiveness of C primary afferent fibres of different origins in evoking a prolonged facilitation of the flexor reflex in the rat. J Neurosci 1986;6:1433-1443.
4. Simone D, Sorkin LS, Oh U, Chung JM, Owens CL, LaMotte RM, Willis WD: Neurogenic hyperalgesia: central correlates in responses of spinothalamic tract neurons. J Neurophys 1991;66:228-246.
5. Dougherty PM, Palecek J, Paleckova V, Sorkin LS, Willis WD: The role of NMDA and non-NMDA excitatory amino acid receptors in the excitation of primate spinothalamic tract neurons by mechanical, chemical, thermal, and electrical stimuli. J Neurosci 1992;12:3025-3041.
6. Malmberg AB, Yaksh TL: Hyperalgesia mediated by spinal glutamate or substance P receptor blocked by spinal cyclooxygenase inhibition. Science 1992;257:1276-1279.
7. 2α to conscious mice. Pain 1992;50:223-229.
8. Uda R, Horiguchi S, Ito S, Hyodo M, Hayaishi O: Nociceptive effects induced by intrathecal administration of prostaglandin D2, E2, or F2α to conscious mice. Brain Res 1990;510:26-32.
9. Kitto KF, Haley JE, Wilcox GL: Involvement of nitric oxide in spinally mediated hyperalgesia in the mouse. Neurosci Lett 1992;148:1-5.
10. Malmberg AB, Yaksh TL: Spinal nitric oxide synthase inhibition blocks NMDA induced thermal hyperalgesia and produces antinociception in the formalin test in rats. Pain 1993;54:291-300.
11. Malmberg AB, Yaksh TL: Antinociceptive actions of spinal non-steroidal anti-inflammatory agents on the formalin test in the rat. J Pharmacol Exp Ther 1992;163: 136-146.
12. Meller ST, Dykstra C, Gebhart GF: Production of endogenous nitric oxide and activation of soluble guanylate cyclase are required for N-methyl-D-aspartate produced facilitation of the nociceptive tail-flick reflex. Eur J Pharmacol 1992;214:93-96.
13. Woolf CJ, Thompson SWN: The induction and maintenance of central sensitization is dependent on N-methyl-D-aspartic acid receptor activation: implications for the treatment of post-injury pain hypersensitivity states. Pain 1991;44:293-299.
14. Chapman V, Dickenson AH: The spinal and peripheral roles of bradykinin and prostaglandins in nociceptive processing in the rat. Eur J Pharmacol 1992;219:427-433.
15. Taiwo YO, Bjerknes LK, Goetzl EJ, Levine JD: Mediation of primary afferent peripheral hyperalgesia by the cAMP second messenger system. Neuroscience 1989;32:577-580.
16. Nicol GD, Klingberg DK, Vasko MR: Prostaglandin E2 increases calcium conductance and stimulates release of substance P in avian sensory neurons. J Neurosci 1992;12: 1917-1927.
17. Garry MG, Richardson JD, Hargreaves KM: Sodium nitroprusside evokes the release of immunoreactive calcitonin gene-related peptide and substance P from dorsal horn slices via nitric oxide-dependent and nitric oxideindependent mechanisms. J Neurosci (in press).
18. Sorkin LS: NMDA evokes an L-NAME sensitive spinal release of glutamate and citrulline. Neuroreport 1993;4: 479-482.
19. Li P, Tong C, Eisenach JC: A bioassay for nitric oxide release from spinal cord. Anesthesiology 1993;79(Suppl): A907.
20. Paleckova V, Palecek J, McAdoo DJ, Willis WD: The non-NMDA antagonist CNQX prevents release of amino acids into the rat spinal cord dorsal horn evoked by sciatic nerve stimulation. Neurosci Lett 1992;148:19-22.
21. Clarke RW, Mathews B: The thresholds of the jaw opening reflex and trigeminal brainstem neurons to tooth-pulp stimulation in acutely and chronically prepared cats. Neuroscience 1990;36:105-114.
22. Hartell NA, Headley PM: Preparative surgery enhances the direct spinal actions of three injectable anesthetics in the anesthetized rat. Pain 1991;46:75-80.
23. Young AM, Bradford HF: N-methyl-D-aspartate releases excitatory amino acids in rat corpus striatum in vivo. J Neurochem 1991;56:1677-1683.
24. Montague PR, Gancayco CD, Winn MJ, Marchase RB, Friedlander MJ: Role of NO production in NMDA receptor-mediated neurotransmitter release in cerebralcortex. Science 1994;263:973-977.
25. Lynch MA, Voss KL: Arachidonic acid increases inositol phospholipid metabolism and glutamate release in synaptosomes prepared from hippocampal tissue. J Neurochem 1990;55:215-221.
26. Tapia-Arancibia L, Rage F, Récasens M, Pin J-P: NMDA receptor activation stimulates phospholipase A2 and somatostatin release from rat cortical neurons in primary cultures. Eur J Pharmacol 1992;225:253-262.
27. Barbour B, Szatkowski M, Ingledew N, Atwell D: Arachidonic acid induces a prolonged inhibition of glutamate uptake into glial cells. Nature 1989;342:918-920.
28. Kanner J, Harel S, Granit R: Nitric oxide, an inhibitor of lipid oxidation by lipoxygenase, cyclooxygenase and hemoglobin. Lipids 1992;27:46-49.
29. Salvemini D, Misko TP, Masferrer JL, Seibert K, Currie MG, Needleman P: Nitric oxide activates cyclooxygenase enzymes. Proc Nat Acad Sci USA 1993;90:7240-7244.