메뉴 건너뛰기




Volumn 58, Issue 3, 2007, Pages 245-249

Involvement of substance P and calcitonin gene-related peptide in development and maintenance of neuropathic pain from spinal nerve injury model of rat

Author keywords

Calcitonin gene related peptide (CGRP); CGRP8 37; L703,606; Nerve injury; Neurokinin 1 antagonist; Neuropathic pain; Substance P

Indexed keywords

2 BENZHYDRYL 3 (2 IODOBENZYLAMINO)QUINUCLIDINE; CALCITONIN GENE RELATED PEPTIDE; CALCITONIN GENE RELATED PEPTIDE RECEPTOR ANTAGONIST; CALCITONIN GENE RELATED PEPTIDE[8-37]; LIDOCAINE; NEUROKININ 1 RECEPTOR ANTAGONIST; SUBSTANCE P; UNCLASSIFIED DRUG;

EID: 34447282998     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neures.2007.03.004     Document Type: Article
Times cited : (89)

References (44)
  • 1
    • 0033798226 scopus 로고    scopus 로고
    • Lack of pre-emptive analgesic effects of local anaesthetics on neuropathic pain
    • Abdi S., Lee D.H., Park S.K., and Chung J.M. Lack of pre-emptive analgesic effects of local anaesthetics on neuropathic pain. Br J Anaesth 85 (2000) 620-623
    • (2000) Br J Anaesth , vol.85 , pp. 620-623
    • Abdi, S.1    Lee, D.H.2    Park, S.K.3    Chung, J.M.4
  • 2
    • 0034193925 scopus 로고    scopus 로고
    • Alleviation of mechanical and thermal allodynia by CGRP(8-37) in a rodent model of chronic central pain
    • Bennett A.D., Chastain K.M., and Hulsebosch C.E. Alleviation of mechanical and thermal allodynia by CGRP(8-37) in a rodent model of chronic central pain. Pain 86 (2000) 163-175
    • (2000) Pain , vol.86 , pp. 163-175
    • Bennett, A.D.1    Chastain, K.M.2    Hulsebosch, C.E.3
  • 3
    • 1642421156 scopus 로고    scopus 로고
    • The role of the N-methyl-d-aspartate receptor NR1 subunit in peripheral nerve injury-induced mechanical allodynia, glial activation and chemokine expression in the mouse
    • Bursztajn S., Rutkowski M.D., and Deleo J.A. The role of the N-methyl-d-aspartate receptor NR1 subunit in peripheral nerve injury-induced mechanical allodynia, glial activation and chemokine expression in the mouse. Neuroscience 125 (2004) 269-275
    • (2004) Neuroscience , vol.125 , pp. 269-275
    • Bursztajn, S.1    Rutkowski, M.D.2    Deleo, J.A.3
  • 4
    • 0036160387 scopus 로고    scopus 로고
    • Attenuation of hyperalgesia in a rat model of neuropathic pain after intrathecal pre- or post-treatment with a neurokinin-1 antagonist
    • Cahill C.M., and Coderre T.J. Attenuation of hyperalgesia in a rat model of neuropathic pain after intrathecal pre- or post-treatment with a neurokinin-1 antagonist. Pain 95 (2002) 277-285
    • (2002) Pain , vol.95 , pp. 277-285
    • Cahill, C.M.1    Coderre, T.J.2
  • 6
    • 0023818868 scopus 로고
    • Effects of intrathecal administration of neuropeptides on a spinal nociceptive reflex in the rat: VIP, galanin, CGRP, TRH, somatostatin and angiotensin II
    • Cridland R.A., and Henry J.L. Effects of intrathecal administration of neuropeptides on a spinal nociceptive reflex in the rat: VIP, galanin, CGRP, TRH, somatostatin and angiotensin II. Neuropeptides 11 (1988) 23-32
    • (1988) Neuropeptides , vol.11 , pp. 23-32
    • Cridland, R.A.1    Henry, J.L.2
  • 7
    • 32644440589 scopus 로고    scopus 로고
    • Spontaneous pain, both neuropathic and inflammatory, is related to frequency of spontaneous firing in intact C-fiber nociceptors
    • Djouhri L., Koutsikou S., Fang X., McMullan S., and Lawson S.N. Spontaneous pain, both neuropathic and inflammatory, is related to frequency of spontaneous firing in intact C-fiber nociceptors. J Neurosci 26 (2006) 1281-1292
    • (2006) J Neurosci , vol.26 , pp. 1281-1292
    • Djouhri, L.1    Koutsikou, S.2    Fang, X.3    McMullan, S.4    Lawson, S.N.5
  • 8
    • 0021369607 scopus 로고
    • Differential slowing and block of conduction by lidocaine in individual afferent myelinated and unmyelinated axons
    • Fink B.R., and Cairns A.M. Differential slowing and block of conduction by lidocaine in individual afferent myelinated and unmyelinated axons. Anesthesiology 60 (1984) 111-120
    • (1984) Anesthesiology , vol.60 , pp. 111-120
    • Fink, B.R.1    Cairns, A.M.2
  • 9
    • 0023711158 scopus 로고
    • Is substance P a primary afferent neurotransmitter for nociceptive input? I. Analysis of pain-related behaviors resulting from intrathecal administration of substance P and 6 excitatory compounds
    • Frenk H., Bossut D., Urca G., and Mayer D.J. Is substance P a primary afferent neurotransmitter for nociceptive input? I. Analysis of pain-related behaviors resulting from intrathecal administration of substance P and 6 excitatory compounds. Brain Res 455 (1988) 223-231
    • (1988) Brain Res , vol.455 , pp. 223-231
    • Frenk, H.1    Bossut, D.2    Urca, G.3    Mayer, D.J.4
  • 10
    • 0032188750 scopus 로고    scopus 로고
    • Change in mRNAs for neuropeptides and the GABA(A) receptor in dorsal root ganglion neurons in a rat experimental neuropathic pain model
    • Fukuoka T., Tokunaga A., Kondo E., Miki K., Tachibana T., and Noguchi K. Change in mRNAs for neuropeptides and the GABA(A) receptor in dorsal root ganglion neurons in a rat experimental neuropathic pain model. Pain 78 (1998) 13-26
    • (1998) Pain , vol.78 , pp. 13-26
    • Fukuoka, T.1    Tokunaga, A.2    Kondo, E.3    Miki, K.4    Tachibana, T.5    Noguchi, K.6
  • 11
    • 27644492388 scopus 로고    scopus 로고
    • Varicella zoster virus induces neuropathic changes in rat dorsal root ganglia and behavioral reflex sensitisation that is attenuated by gabapentin or sodium channel blocking drugs
    • Garry E.M., Delaney A., Anderson H.A., Sirinathsinghji E.C., Clapp R.H., Martin W.J., et al. Varicella zoster virus induces neuropathic changes in rat dorsal root ganglia and behavioral reflex sensitisation that is attenuated by gabapentin or sodium channel blocking drugs. Pain 118 (2005) 97-111
    • (2005) Pain , vol.118 , pp. 97-111
    • Garry, E.M.1    Delaney, A.2    Anderson, H.A.3    Sirinathsinghji, E.C.4    Clapp, R.H.5    Martin, W.J.6
  • 12
    • 0033913719 scopus 로고    scopus 로고
    • Evaluation of selective NK(1) receptor antagonist CI-1021 in animal models of inflammatory and neuropathic pain
    • Gonzalez M.I., Field M.J., Hughes J., and Singh L. Evaluation of selective NK(1) receptor antagonist CI-1021 in animal models of inflammatory and neuropathic pain. J Pharmacol Exp Ther 294 (2000) 444-450
    • (2000) J Pharmacol Exp Ther , vol.294 , pp. 444-450
    • Gonzalez, M.I.1    Field, M.J.2    Hughes, J.3    Singh, L.4
  • 13
    • 0033586254 scopus 로고    scopus 로고
    • Effect of post-injury NMDA antagonist treatment on long-term Fos expression and hyperalgesia in a model of chronic neuropathic pain
    • Hudspith M.J., Harrisson S., Smith G., Bountra C., Elliot P.J., Birch P.J., et al. Effect of post-injury NMDA antagonist treatment on long-term Fos expression and hyperalgesia in a model of chronic neuropathic pain. Brain Res 822 (1999) 220-227
    • (1999) Brain Res , vol.822 , pp. 220-227
    • Hudspith, M.J.1    Harrisson, S.2    Smith, G.3    Bountra, C.4    Elliot, P.J.5    Birch, P.J.6
  • 14
    • 33748754869 scopus 로고    scopus 로고
    • Loss of spinal substance P pain transmission under the condition of LPA1 receptor-mediated neuropathic pain
    • Inoue M., Yamaguchi A., Kawakami M., Chun J., and Ueda H. Loss of spinal substance P pain transmission under the condition of LPA1 receptor-mediated neuropathic pain. Mol Pain 2 (2006) 25
    • (2006) Mol Pain , vol.2 , pp. 25
    • Inoue, M.1    Yamaguchi, A.2    Kawakami, M.3    Chun, J.4    Ueda, H.5
  • 15
    • 1842685406 scopus 로고    scopus 로고
    • Involvement of peripherally released substance P and calcitonin gene-related peptide in mediating mechanical hyperalgesia in a traumatic neuropathy model of the rat
    • Jang J.H., Nam T.S., Paik K.S., and Leem J.W. Involvement of peripherally released substance P and calcitonin gene-related peptide in mediating mechanical hyperalgesia in a traumatic neuropathy model of the rat. Neurosci Lett 360 (2004) 129-132
    • (2004) Neurosci Lett , vol.360 , pp. 129-132
    • Jang, J.H.1    Nam, T.S.2    Paik, K.S.3    Leem, J.W.4
  • 16
    • 0037109674 scopus 로고    scopus 로고
    • Spinal neurons that possess the substance P receptor are required for the development of central sensitization
    • Khasabov S.G., Rogers S.D., Ghilardi J.R., Peters C.M., Mantyh P.W., and Simone D.A. Spinal neurons that possess the substance P receptor are required for the development of central sensitization. J Neurosci 22 (2002) 9086-9098
    • (2002) J Neurosci , vol.22 , pp. 9086-9098
    • Khasabov, S.G.1    Rogers, S.D.2    Ghilardi, J.R.3    Peters, C.M.4    Mantyh, P.W.5    Simone, D.A.6
  • 17
    • 0026727999 scopus 로고
    • An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat
    • Kim S.H., and Chung J.M. An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat. Pain 50 (1992) 355-363
    • (1992) Pain , vol.50 , pp. 355-363
    • Kim, S.H.1    Chung, J.M.2
  • 18
    • 0035260151 scopus 로고    scopus 로고
    • Effects of iontophoretically applied substance P, calcitonin gene-related peptide on excitability of dorsal horn neurones in rats
    • Leem J.W., Gwak Y.S., Lee E.H., Chung S.S., Kim Y.S., and Nam T.S. Effects of iontophoretically applied substance P, calcitonin gene-related peptide on excitability of dorsal horn neurones in rats. Yonsei Med J 42 (2001) 74-83
    • (2001) Yonsei Med J , vol.42 , pp. 74-83
    • Leem, J.W.1    Gwak, Y.S.2    Lee, E.H.3    Chung, S.S.4    Kim, Y.S.5    Nam, T.S.6
  • 19
    • 0031839881 scopus 로고    scopus 로고
    • Increase of preprotachykinin mRNA and substance P immunoreactivity in spared dorsal root ganglion neurons following partial sciatic nerve injury
    • Ma W., and Bisby M.A. Increase of preprotachykinin mRNA and substance P immunoreactivity in spared dorsal root ganglion neurons following partial sciatic nerve injury. Eur J Neurosci 10 (1998) 2388-2399
    • (1998) Eur J Neurosci , vol.10 , pp. 2388-2399
    • Ma, W.1    Bisby, M.A.2
  • 20
    • 0036711470 scopus 로고    scopus 로고
    • Partial sciatic nerve ligation induces increase in the phosphorylation of extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) in astrocytes in the lumbar spinal dorsal horn and the gracile nucleus
    • Ma W., and Quirion R. Partial sciatic nerve ligation induces increase in the phosphorylation of extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) in astrocytes in the lumbar spinal dorsal horn and the gracile nucleus. Pain 99 (2002) 175-184
    • (2002) Pain , vol.99 , pp. 175-184
    • Ma, W.1    Quirion, R.2
  • 21
    • 0032874158 scopus 로고    scopus 로고
    • Increased calcitonin gene-related peptide immunoreactivity in gracile nucleus after partial sciatic nerve injury: age-dependent and originating from spared sensory neurons
    • Ma W., Ramer M.S., and Bisby M.A. Increased calcitonin gene-related peptide immunoreactivity in gracile nucleus after partial sciatic nerve injury: age-dependent and originating from spared sensory neurons. Exp Neurol 159 (1999) 459-473
    • (1999) Exp Neurol , vol.159 , pp. 459-473
    • Ma, W.1    Ramer, M.S.2    Bisby, M.A.3
  • 22
    • 0033983432 scopus 로고    scopus 로고
    • Abnormal substance P release from the spinal cord following injury to primary sensory neurons
    • Malcangio M., Ramer M.S., Jones M.G., and McMahon S.B. Abnormal substance P release from the spinal cord following injury to primary sensory neurons. Eur J Neurosci 12 (2000) 397-399
    • (2000) Eur J Neurosci , vol.12 , pp. 397-399
    • Malcangio, M.1    Ramer, M.S.2    Jones, M.G.3    McMahon, S.B.4
  • 23
    • 0034007744 scopus 로고    scopus 로고
    • Nerve injury-induced mechanical but not thermal hyperalgesia is attenuated in neurokinin-1 receptor knockout mice
    • Mansikka H., Sheth R.N., DeVries C., Lee H., Winchurch R., and Raja S.N. Nerve injury-induced mechanical but not thermal hyperalgesia is attenuated in neurokinin-1 receptor knockout mice. Exp Neurol 162 (2000) 343-349
    • (2000) Exp Neurol , vol.162 , pp. 343-349
    • Mansikka, H.1    Sheth, R.N.2    DeVries, C.3    Lee, H.4    Winchurch, R.5    Raja, S.N.6
  • 24
    • 0027936177 scopus 로고
    • Altered tachykinin expression by dorsal root ganglion neurons in a rat model of neuropathic pain
    • Marchand J.E., Wurm W.H., Kato T., and Kream R.M. Altered tachykinin expression by dorsal root ganglion neurons in a rat model of neuropathic pain. Pain 58 (1994) 219-231
    • (1994) Pain , vol.58 , pp. 219-231
    • Marchand, J.E.1    Wurm, W.H.2    Kato, T.3    Kream, R.M.4
  • 25
    • 0034720177 scopus 로고    scopus 로고
    • Allodynia and hyperalgesia evoked by sciatic mononeuropathy in NKI receptor knockout mice
    • Martinez-Caro L., and Laird J.M. Allodynia and hyperalgesia evoked by sciatic mononeuropathy in NKI receptor knockout mice. Neuroreport 11 (2000) 1213-1217
    • (2000) Neuroreport , vol.11 , pp. 1213-1217
    • Martinez-Caro, L.1    Laird, J.M.2
  • 26
    • 0018663481 scopus 로고
    • Brain peptides: is substance P a transmitter of pain signals?
    • Marx J.L. Brain peptides: is substance P a transmitter of pain signals?. Science 205 (1979) 886-889
    • (1979) Science , vol.205 , pp. 886-889
    • Marx, J.L.1
  • 27
    • 1642398355 scopus 로고    scopus 로고
    • Functional role of exogenous administration of substance P in chronic constriction injury model of neuropathic pain in gerbils
    • Meert T.F., Vissers K., Geenen F., and Kontinen V.K. Functional role of exogenous administration of substance P in chronic constriction injury model of neuropathic pain in gerbils. Pharmacol Biochem Behav 76 (2003) 17-25
    • (2003) Pharmacol Biochem Behav , vol.76 , pp. 17-25
    • Meert, T.F.1    Vissers, K.2    Geenen, F.3    Kontinen, V.K.4
  • 28
    • 0342275181 scopus 로고    scopus 로고
    • Calcitonin gene-related peptide increase in the rat spinal dorsal horn and dorsal column nucleus following peripheral nerve injury: up-regulation in a subpopulation of primary afferent sensory neurons
    • Miki K., Fukuoka T., Tokunaga A., and Noguchi K. Calcitonin gene-related peptide increase in the rat spinal dorsal horn and dorsal column nucleus following peripheral nerve injury: up-regulation in a subpopulation of primary afferent sensory neurons. Neuroscience 82 (1998) 1243-1252
    • (1998) Neuroscience , vol.82 , pp. 1243-1252
    • Miki, K.1    Fukuoka, T.2    Tokunaga, A.3    Noguchi, K.4
  • 29
    • 0028275237 scopus 로고
    • Primary sensory neurons exhibit altered gene expression in a rat model of neuropathic pain
    • Nahin R.L., Ren K., De Leon M., and Ruda M. Primary sensory neurons exhibit altered gene expression in a rat model of neuropathic pain. Pain 58 (1994) 95-108
    • (1994) Pain , vol.58 , pp. 95-108
    • Nahin, R.L.1    Ren, K.2    De Leon, M.3    Ruda, M.4
  • 30
    • 0029954092 scopus 로고    scopus 로고
    • Inflammatory pain hypersensitivity mediated by phenotypic switch in myelinated primary sensory neurons
    • Neumann S., Doubell T.P., Leslie T., and Woolf C.J. Inflammatory pain hypersensitivity mediated by phenotypic switch in myelinated primary sensory neurons. Nature 384 (1996) 360-364
    • (1996) Nature , vol.384 , pp. 360-364
    • Neumann, S.1    Doubell, T.P.2    Leslie, T.3    Woolf, C.J.4
  • 31
    • 10844241535 scopus 로고    scopus 로고
    • Differential activation of MAPK in injured and uninjured DRG neurons following chronic constriction injury of the sciatic nerve in rats
    • Obata K., Yamanaka H., Dai Y., Mizushima T., Fukuoka T., Tokunaga A., et al. Differential activation of MAPK in injured and uninjured DRG neurons following chronic constriction injury of the sciatic nerve in rats. Eur J Neurosci 20 (2004) 2881-2895
    • (2004) Eur J Neurosci , vol.20 , pp. 2881-2895
    • Obata, K.1    Yamanaka, H.2    Dai, Y.3    Mizushima, T.4    Fukuoka, T.5    Tokunaga, A.6
  • 35
    • 15044365663 scopus 로고    scopus 로고
    • Mechanical and heat sensitization of cutaneous nociceptors in rats with experimental peripheral neuropathy
    • Shim B., Kim D.W., Kim B.H., Nam T.S., Leem J.W., and Chung J.M. Mechanical and heat sensitization of cutaneous nociceptors in rats with experimental peripheral neuropathy. Neuroscience 132 (2005) 193-201
    • (2005) Neuroscience , vol.132 , pp. 193-201
    • Shim, B.1    Kim, D.W.2    Kim, B.H.3    Nam, T.S.4    Leem, J.W.5    Chung, J.M.6
  • 36
    • 0028803311 scopus 로고
    • Neurotransmitters in the spinal cord dorsal horn in a model of painful neuropathy and in nerve crush
    • Sommer C., and Myers R.R. Neurotransmitters in the spinal cord dorsal horn in a model of painful neuropathy and in nerve crush. Acta Neuropathol (Berl) 90 (1995) 478-485
    • (1995) Acta Neuropathol (Berl) , vol.90 , pp. 478-485
    • Sommer, C.1    Myers, R.R.2
  • 37
    • 14844293564 scopus 로고    scopus 로고
    • Calcitonin gene-related peptide receptor activation produces PKA- and PKC-dependent mechanical hyperalgesia and central sensitization
    • Sun R.Q., Tu Y.J., Lawand N.B., Yan J.Y., Lin Q., and Willis W.D. Calcitonin gene-related peptide receptor activation produces PKA- and PKC-dependent mechanical hyperalgesia and central sensitization. J Neurophysiol 92 (2004) 2859-2866
    • (2004) J Neurophysiol , vol.92 , pp. 2859-2866
    • Sun, R.Q.1    Tu, Y.J.2    Lawand, N.B.3    Yan, J.Y.4    Lin, Q.5    Willis, W.D.6
  • 38
    • 0346655315 scopus 로고    scopus 로고
    • Activation of p38 mitogen-activated protein kinase in spinal hyperactive microglia contributes to pain hypersensitivity following peripheral nerve injury
    • Tsuda M., Mizokoshi A., Shigemoto-Mogami Y., Koizumi S., and Inoue K. Activation of p38 mitogen-activated protein kinase in spinal hyperactive microglia contributes to pain hypersensitivity following peripheral nerve injury. Glia 45 (2004) 89-95
    • (2004) Glia , vol.45 , pp. 89-95
    • Tsuda, M.1    Mizokoshi, A.2    Shigemoto-Mogami, Y.3    Koizumi, S.4    Inoue, K.5
  • 39
    • 28444442683 scopus 로고    scopus 로고
    • Molecular mechanisms of neuropathic pain-phenotypic switch and initiation mechanisms
    • Ueda H. Molecular mechanisms of neuropathic pain-phenotypic switch and initiation mechanisms. Pharmacol Ther 109 (2006) 57-77
    • (2006) Pharmacol Ther , vol.109 , pp. 57-77
    • Ueda, H.1
  • 40
    • 0035038778 scopus 로고    scopus 로고
    • Role of neurotransmitters in sensitization of pain responses
    • Willis W.D. Role of neurotransmitters in sensitization of pain responses. Ann N Y Acad Sci 933 (2001) 142-156
    • (2001) Ann N Y Acad Sci , vol.933 , pp. 142-156
    • Willis, W.D.1
  • 41
    • 25644454237 scopus 로고    scopus 로고
    • NMDA receptor antagonist treatment at the time of nerve injury prevents injury-induced changes in spinal NR1 and NR2B subunit expression and increases the sensitivity of residual pain behaviours to subsequently administered NMDA receptor antagonists
    • Wilson J.A., Garry E.M., Anderson H.A., Rosie R., Colvin L.A., Mitchell R., et al. NMDA receptor antagonist treatment at the time of nerve injury prevents injury-induced changes in spinal NR1 and NR2B subunit expression and increases the sensitivity of residual pain behaviours to subsequently administered NMDA receptor antagonists. Pain 117 (2005) 421-432
    • (2005) Pain , vol.117 , pp. 421-432
    • Wilson, J.A.1    Garry, E.M.2    Anderson, H.A.3    Rosie, R.4    Colvin, L.A.5    Mitchell, R.6
  • 42
    • 0027751032 scopus 로고
    • The pathophysiology of peripheral neuropathic pain-abnormal peripheral input and abnormal central processing
    • Woolf C.J. The pathophysiology of peripheral neuropathic pain-abnormal peripheral input and abnormal central processing. Acta Neurochir Suppl (Wien) 58 (1993) 125-130
    • (1993) Acta Neurochir Suppl (Wien) , vol.58 , pp. 125-130
    • Woolf, C.J.1
  • 43
    • 0032104203 scopus 로고    scopus 로고
    • Null mutations lacking substance: elucidating pain mechanisms by genetic pharmacology
    • Woolf C.J., Mannion R.J., and Neumann S. Null mutations lacking substance: elucidating pain mechanisms by genetic pharmacology. Neuron 20 (1998) 1063-1066
    • (1998) Neuron , vol.20 , pp. 1063-1066
    • Woolf, C.J.1    Mannion, R.J.2    Neumann, S.3
  • 44
    • 33747879281 scopus 로고    scopus 로고
    • Alteration in sensitivity of ionotropic glutamate receptors and tachykinin receptors in spinal cord contribute to development and maintenance of nerve injury-evoked neuropathic pain
    • Yoshimura M., and Yonehara N. Alteration in sensitivity of ionotropic glutamate receptors and tachykinin receptors in spinal cord contribute to development and maintenance of nerve injury-evoked neuropathic pain. Neurosci Res 56 (2006) 21-28
    • (2006) Neurosci Res , vol.56 , pp. 21-28
    • Yoshimura, M.1    Yonehara, N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.