Modulation of the heteromeric Kir4.1-Kir5.1 channel by multiple neurotransmitters via Gαq-coupled receptors

Journal of Cellular Physiology

Volumn 214, Issue 1, 2008, Pages 84-95

  Rojas, Asheebo ^a   Su, Junda ^a   Yang, Liang ^a   Lee, Ming ^a   Cui, Ningren ^a   Zhang, Xiaoli ^a   Fountain, Dyanna ^a   Jiang, Chun ^a  

^a GEORGIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON DIOXIDE; G PROTEIN COUPLED RECEPTOR; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.2; KIR4.1 CHANNEL; KIR5.1 CHANNEL; NEUROTRANSMITTER; PROTEIN KINASE C; PROTIRELIN; SEROTONIN; SUBSTANCE P; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN STEM; CHEMOSENSITIVITY; IMMUNOHISTOCHEMISTRY; NERVE CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; OOCYTE; PH; PRESSURE; PRIORITY JOURNAL; RESPIRATION CONTROL; SENSITIVITY ANALYSIS; XENOPUS;

ANIMALS; CELL CULTURE TECHNIQUES; CELLS, CULTURED; DNA, COMPLEMENTARY; ELECTROPHYSIOLOGY; EMBRYO, MAMMALIAN; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; IMMUNOHISTOCHEMISTRY; MEDULLA OBLONGATA; MEMBRANE POTENTIALS; MICROELECTRODES; MICROINJECTIONS; NEURONS; NEUROTRANSMITTER AGENTS; OOCYTES; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, G-PROTEIN-COUPLED; TIME FACTORS; XENOPUS LAEVIS;

EID: 36849030838     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.21169     Document Type: Article

References (57)

1. + channels are effectors for transmitter-induced slow excitation in brain neurons. Proc Natl Acad Sci USA 99:14494-14499.
2. Casamassima M, D'Adamo MC, Pessia M, Tucker SJ. 2003. Identification of a heteromeric interaction that influences the rectification, gating, and pH sensitivity of Kir4.1/Kir5.1 potassium channels. J Biol Chem 278:43533-43540.
3. Cream CL, Li A, Nattie EE. 1997. RTN TRH causes prolonged respiratory stimulation. J Appl Physiol 83:792-799.
4. 2) at physiological levels. J Cell Physiol 189:229-236.
5. Dekin MS, Richerson GB, Getting PA. 1985. Thyrotropin-releasing hormone induces rhythmic bursting in neurons of the nucleus tractus solitarius. Science 229:67-69.
6. + channels are regulated independently by protein kinases and ATP hydrolysis. Neuron 13:1413-1420.
7. Feldman JL, Mitchell GS, Nattie EE. 2003. Breathing: Rhythmicity, plasticity, chemosensitivity. Annu Rev Neurosci 26:239-266.
8. Gustafsson B, Jankowska E. 1976. Direct and indirect activation of nerve cells by electrical pulses applied extracellularly. J Physiol 258:33-61.
9. + channels expressed in Xenopus oocytes. J Physiol 495:681-688.
10. + channel, Kir4.1, in satellite cells of rat cochlear ganglia. Am J Physiol 277:C638-C644.
11. + channel subunits, Kir4.1 and Kir5.1, in brain astrocytes. J Biol Chem 279:44065-44073.
12. + channel, Kir4.1, expressed in astrocytes surrounds synapses and blood vessels in brain. Am J Physiol Cell Physiol 281:C922-C931.
13. 2 sensitivity after neurotoxic lesions in the medullary raphe area of awake goats. J Appl Physiol 97:2236-2247.
14. Horn CC, Friedman MI. 2003. Detection of single unit activity from the rat vagus using cluster analysis of principal components. J Neurosci Methods 122:141-147.
15. + channels in retina. Am J Physiol Cell Physiol 285:C260-C267.
16. + channel, K(AB)-2 (Kir4.1), in the basolateral membrane of renal distal tubular epithelia. FEBS Lett 388;11-15.
17. Jan LY, Jan YN. 1997. Voltage-gated and inwardly rectifying potassium channels. J Physiol 505:267-282.
18. Jiang C, Lipski J. 1990. Extensive monosynaptic inhibition of ventral respiratory group neurons by augmenting neurons in the Botzinger complex in the cat. Exp Brain Res 81:639-648.
19. 2 central chemosensitivity: Why are there so many sensing molecules? Respir Physiol Neurobiol 145:115-126.
20. Koike-Tani M, Collins JM, Kawano T, Zhao P, Zhao Q, Kozasa T, Nakajima S, Nakajima Y. 2005. Signal transduction pathway for the substance P-induced inhibition of rat Kir3 (GIRK) channel. J Physiol 564:489-500.
21. Konstas AA, Korbmacher C, Tucker SJ. 2003. Identification of domains that control the heteromeric assembly of Kir5.1/Kir4.0 potassium channels. Am J Physiol Cell Physiol 284:C910-C917.
22. + channel, Kir4.1, in rat retinal pigment epithelium. J Physiol 520:373-381.
23. αq family subunits, phospholipase C, and a readily diffusible messenger. J Biol Chem 276:16720-16730.
24. Light PE, Bladen C, Winkfein RJ, Walsh MP, French RJ. 2000. Molecular basis of protein kinase C-induced activation of ATP-sensitive potassium channels. Proc Natl Acad Sci USA 97:9058-9063.
25. + channels (GIRKs) mediate postsynaptic but not presynaptic transmitter actions in hippocampal neurons. Neuron 19:687-695.
26. + channels by protein kinase C. Proc Natl Acad Sci USA 101:1087-1092.
27. Moss IR, Denavit-Saubie M, Eldridge FL, Gillis RA, Herkenham M, Lahiri S. 1986. Neuromodulators and transmitters in respiratory control. Fed Proc 45:2133-2147.
28. Mutolo D, Bongianni F, Carfi M, Pantaleo T. 1999. Respiratory responses to thyrotropin-releasing hormone microinjected into the rabbit medulla oblongata. Am J Physiol 277:R1331-R1338.
29. 2, brainstem chemoreceptors and breathing. Prog Neurobiol 59:299-331.
30. Nattie EE, Li A. 2002. Substance P-saporin lesion of neurons with NK1 receptors in one chemoreceptor site in rats decreases ventilation and chemosensitivity. J Physiol 544:603-616.
31. Nattie EE, Li A, Richerson G, Lappi DA. 2004. Medullary serotonergic neurones and adjacent neurones that express neurokinin-1 receptors are both involved in chemoreception in vivo. J Physiol 556:235-253.
32. Nichols CG, Lopatin AN. 1997. Inward rectifier potassium channels. Annu Rev Physiol 59:171-191.
33. Nink M, Krause U, Lehnert H, Heuberger W, Huber I, Schulz R, Hommel G, Beyer J. 1991. Thyrotropin-re leasing hormone has stimulatory effects on ventilation in humans. Acta Physiol Scand 141:309-318.
34. + channels. EMBO J 15:2980-2987.
35. Pessia M, Imbrici P, D'Adamo MC, Salvatore L, Tucker SJ. 2001. Differential pH sensitivity of Kir4.1 and Kir4.2 potassium channels and their modulation by heteropolymerisation with Kir5.1. J Physiol 532:359-367.
36. 2-induced c-Fos expression in brainstem preprotachykinin mRNA containing neurons. Respir Physiol Neurobiol 130:265-274.
37. Richerson GB. 2004. Serotonergic neurons as carbon dioxide sensors that maintain pH homeostasis. Nat Rev Neurosci 5:449-461.
38. Richerson GB, Wang W, Hodges MR, Dohle CI, Diez-Sampedro A. 2005. Homing In on the specific phenotype(s) of central respiratory che more ceptors. Exp Physiol 90:259-266.
39. Schulz R, Nink M, Werner GS, Andreas S, Kreuzer H, Beyer J, Lehnert H. 1996. Human corticotropin-releasing hormone and thyrotropin-releasing hormone modulate the hypercapnic ventilatory response in humans. Eur J Clin Invest 26:989-995.
40. Severson CA, Wang W, Pieribone VA, Dohle CI, Richerson GB. 2003. Midbrain serotonergic neurons are central pH chemo receptors. Nat Neurosci 6:1139-1140.
41. Su J, Jiang C. 2006. Multicellular recordings of cultured brainstem neurons in microelectrode arrays. Cell Tissue Res 326:25-33.
42. 2 chemosensitivity versus wide sensing spectrum: A paradoxical problem and its solutions in cultured brainstem neurons. J Physiol 578:831-841.
43. Talley EM, Bayliss DA. 2002. Modulation of TASK-1 (Kcnk3) and TASK-3 (Kcnk9) potassium channels: Volatile anesthetics and neurotransmitters share a molecular site of action. J Biol Chem 277:17733-17742.
44. + channel, is modulated by multiple neurotransmitters in motoneurons. Neuron 25:399-410.
45. + channel by heteromeric subunit assembly of Kir5.1 with Kir4.1. J Physiol 525:587-592.
46. Taylor NC, Li A, Nattie EE. 2005. Medullary serotonergic neurones modulate the ventilatory response to hypercapnia, but not hypoxia in conscious rats. J Physiol 566:543-557.
47. Tucker SJ, Imbrici P, Salvatore L, D'Adamo MC, Pessia M. 2000. pH dependence of the inwardly rectifying potassium channel, Kir5.1, and localization in renal tubular epithelia. J Biol Chem 275:16404-16407.
48. Wang W, Tiwari JK, Bradley SR, Zaykin RV, Richerson GB. 2001. Acidosis-stimulated neurons of the medullary raphe are serotonergic. J Neurophysiol 85:2224-2235.
49. Wenninger JM, Pan LG, Klum L, Leekley T, Bastastic J, Hodges MR, Feroah TR, Davis S, Forster HV. 2004a. Large lesions in the pre-Botzinger complex area eliminate eupneic respiratory rhythm in awake goats. J Appl Physiol 97:1629-1636.
50. Wenninger JM, Pan LG, Klum L, Leekley T, Bastastic J, Hodges MR, Feroah T, Davis S, Forster HV. 2004b. Small reduction of neurokinin-1 receptor-expressing neurons in the pre-Botzinger complex area induces abnormal breathing periods in awake goats. J Appl Physiol 97:1620-1628.
51. 2-sensitive Kir channels in brainstem neurons of rats. J Membr Biol 197:179-191.
52. Xu H, Cui N, Yang Z, Qu Z, Jiang C. 2000a. Modulation of kir4.1 and kir5.1 by hypercapnia and intracellular acidosis. J Physiol 524:725-735.
53. Xu H, Yang Z, Cui N, Giwa LR, Abdulkadir L, Patel M, Sharma P, Shan G, Shen W, Jiang C. 2000b. Molecular determinants for the distinct pH sensitivity of Kir1.1 and Kir4.1 channels. Am J Physiol Cell Physiol 279:C1464-C1471.
54. Xu H, Yang Z, Cui N, Chanchevalap S, Valesky WW, Jiang C. 2000c. A single residue contributes to the difference between Kir4.1 and Kir1.1 channels in pH sensitivity, rectification and single channel conductance. J Physiol 528:267-277.
55. Yamada M, Inanobe A, Kurachi Y. 1998. G protein regulation of potassium ion channels. Pharmacol Rev 50:723-760.
56. 2 and pH. J Gen Physiol 116:33-45.
57. Zhu G, Qu Z, Cui N, Jiang C. 1999. Suppression of Kir2.3 activity by protein kinase C phosphorylation of the channel protein at threonine 53. J Biol Chem 274:11643-11646.