메뉴 건너뛰기




Volumn 6, Issue 6 SUPPL., 1996, Pages

Role of oxidant stress in the adult respiratory distress syndrome: Evaluation of a novel antioxidant strategy in a porcine model of endotoxin-induced acute lung injury

Author keywords

[No Author keywords available]

Indexed keywords

1,3-DIMETHYLTHIOUREA; ACETYLCYSTEINE; CATALASE; DIMETHYLTHIOUREA; DRUG DERIVATIVE; ENDOTOXIN; ETHYLENEDIAMINE DERIVATIVE; LIPOPOLYSACCHARIDE; N,N' BIS(SALICYLIDENEAMINO)ETHANE MANGANESE(II); N,N'-BIS(SALICYLIDENEAMINO)ETHANE-MANGANESE(II); ORGANOMETALLIC COMPOUND; REACTIVE OXYGEN METABOLITE; SCAVENGER; SUPEROXIDE DISMUTASE; THIOUREA;

EID: 0029680965     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/00024382-199610001-00006     Document Type: Review
Times cited : (84)

References (54)
  • 1
    • 85047679198 scopus 로고
    • The oxygen free radical system: From equations through membrane-protein interactions to cardiovascular injury and protection
    • Kukreja RC, Hess ML: The oxygen free radical system: From equations through membrane-protein interactions to cardiovascular injury and protection. Cardiovasc Res 26:641-655, 1992.
    • (1992) Cardiovasc Res , vol.26 , pp. 641-655
    • Kukreja, R.C.1    Hess, M.L.2
  • 2
    • 0024780087 scopus 로고
    • Free radicals, reactive oxygen species and human disease: A critical evaluation with special reference to atherosclerosis
    • Halliwell B: Free radicals, reactive oxygen species and human disease: A critical evaluation with special reference to atherosclerosis. Br J Exp Pathol 70:737-757, 1989.
    • (1989) Br J Exp Pathol , vol.70 , pp. 737-757
    • Halliwell, B.1
  • 3
    • 0028210533 scopus 로고
    • Free radical chemistry of nitric oxide: Looking at the dark side
    • Freeman B: Free radical chemistry of nitric oxide: Looking at the dark side. Chest 105:79S-84S, 1994.
    • (1994) Chest , vol.105
    • Freeman, B.1
  • 4
    • 0025940823 scopus 로고
    • Mechanisms of neutrophil-mediated tissue injury
    • Anderson BO, Brown JM, Harken AH: Mechanisms of neutrophil-mediated tissue injury. J Surg Res 51:170-179, 1991.
    • (1991) J Surg Res , vol.51 , pp. 170-179
    • Anderson, B.O.1    Brown, J.M.2    Harken, A.H.3
  • 5
    • 0024852764 scopus 로고
    • Reperfusion injury following circulatory collapse: The role of reactive oxygen metabolites
    • Carden DL, Smith JK, Zimmerman BJ, Korthuis RJ, Granger DN: Reperfusion injury following circulatory collapse: The role of reactive oxygen metabolites. J Crit Care 4:294-307, 1989.
    • (1989) J Crit Care , vol.4 , pp. 294-307
    • Carden, D.L.1    Smith, J.K.2    Zimmerman, B.J.3    Korthuis, R.J.4    Granger, D.N.5
  • 6
    • 0024203618 scopus 로고
    • Role of xanthine oxidase and granulocytes in ischemia-reperfusion injury
    • Granger DN: Role of xanthine oxidase and granulocytes in ischemia-reperfusion injury. Am J Physiol 255:H1269-H1275, 1988.
    • (1988) Am J Physiol , vol.255
    • Granger, D.N.1
  • 7
    • 0026335306 scopus 로고
    • Iron chelation with deferoxamine conjugate in hemorrhagic shock
    • Jacobs DM, Julsud JM, Bubrick MP: Iron chelation with deferoxamine conjugate in hemorrhagic shock. J Surg Res 51:484-490, 1991.
    • (1991) J Surg Res , vol.51 , pp. 484-490
    • Jacobs, D.M.1    Julsud, J.M.2    Bubrick, M.P.3
  • 8
    • 0025847804 scopus 로고
    • Fluid resuscitation with deferoxamine prevents systemic bum-induced oxidant injury
    • Demling R, Lalonde C, Knox J, Youn Y-K, Zhu D, Daryani R: Fluid resuscitation with deferoxamine prevents systemic bum-induced oxidant injury. J Trauma 31:538-544, 1991.
    • (1991) J Trauma , vol.31 , pp. 538-544
    • Demling, R.1    Lalonde, C.2    Knox, J.3    Youn, Y.-K.4    Zhu, D.5    Daryani, R.6
  • 9
    • 0026547569 scopus 로고
    • The adult respiratory distress syndrome: A report of survival and modifying factors
    • Suchyta MR, Clemmer TP, Elliott CG, Orme JF, Weaver LK: The adult respiratory distress syndrome: A report of survival and modifying factors. Chest 101:1074-1079, 1992.
    • (1992) Chest , vol.101 , pp. 1074-1079
    • Suchyta, M.R.1    Clemmer, T.P.2    Elliott, C.G.3    Orme, J.F.4    Weaver, L.K.5
  • 10
    • 0027700403 scopus 로고
    • Prediction of survival and mortality in patients with adult respiratory distress syndrome
    • Hyers TM: Prediction of survival and mortality in patients with adult respiratory distress syndrome. New Horizons 1:466-470, 1993.
    • (1993) New Horizons , vol.1 , pp. 466-470
    • Hyers, T.M.1
  • 11
    • 0020522762 scopus 로고
    • Adult respiratory distress syndrome: Risk with common predispositions
    • Fowler AA, Hamman RF, Good JT, et al: Adult respiratory distress syndrome: Risk with common predispositions. Ann Intern Med 98:593-597, 1983.
    • (1983) Ann Intern Med , vol.98 , pp. 593-597
    • Fowler, A.A.1    Hamman, R.F.2    Good, J.T.3
  • 12
    • 0017333439 scopus 로고
    • Pulmonary hypertension in severe acute respiratory failure
    • Zapol WM, Snider MT: Pulmonary hypertension in severe acute respiratory failure. N Engl J Med 296:476-480, 1977.
    • (1977) N Engl J Med , vol.296 , pp. 476-480
    • Zapol, W.M.1    Snider, M.T.2
  • 13
    • 0023719313 scopus 로고
    • An expanded definition of the adult respiratory distress syndrome
    • Murray JF, Matthay MA, Luce JM, Flick MR: An expanded definition of the adult respiratory distress syndrome. Am Rev Respir Dis 138:720-723, 1988.
    • (1988) Am Rev Respir Dis , vol.138 , pp. 720-723
    • Murray, J.F.1    Matthay, M.A.2    Luce, J.M.3    Flick, M.R.4
  • 14
    • 0021857103 scopus 로고    scopus 로고
    • Causes of mortality in patients with the adult respiratory distress syndrome
    • 198
    • Montgomery AB, Stager MA, Carrico CJ, Hudson LD: Causes of mortality in patients with the adult respiratory distress syndrome. Am Rev Respir Dis 132:485-489, 198.
    • Am Rev Respir Dis , vol.132 , pp. 485-489
    • Montgomery, A.B.1    Stager, M.A.2    Carrico, C.J.3    Hudson, L.D.4
  • 15
    • 0027933938 scopus 로고
    • Serum lipofuscin as a prognostic indicator of adult respiratory distress syndrome and multiple organ failure
    • Roumen RMH, Hendriks Th, de Man BM, Goris RJA: Serum lipofuscin as a prognostic indicator of adult respiratory distress syndrome and multiple organ failure. Br J Surgery 81:1300-1305, 1994.
    • (1994) Br J Surgery , vol.81 , pp. 1300-1305
    • Roumen, R.M.H.1    Hendriks, Th.2    De Man, B.M.3    Goris, R.J.A.4
  • 16
    • 0024582090 scopus 로고
    • Differences in tocopherol-lipid ratios in ARDS and non-ARDS patients
    • Bertrand Y, Pincemail J, Hanique G, et al: Differences in tocopherol-lipid ratios in ARDS and non-ARDS patients. Intensive Care Med 15:87-93, 1989.
    • (1989) Intensive Care Med , vol.15 , pp. 87-93
    • Bertrand, Y.1    Pincemail, J.2    Hanique, G.3
  • 17
    • 0025347229 scopus 로고
    • Oxidative stress and abnormal cholesterol metabolism in patients with adult respiratory distress syndrome
    • Cross CF, Forte T, Stocker R, et al: Oxidative stress and abnormal cholesterol metabolism in patients with adult respiratory distress syndrome. J Lab Clin Med 115:396-404, 1990.
    • (1990) J Lab Clin Med , vol.115 , pp. 396-404
    • Cross, C.F.1    Forte, T.2    Stocker, R.3
  • 18
    • 0025064166 scopus 로고
    • Vitamin E deficiency, lipoperoxidation during adult respiratory distress syndrome
    • Richard C, Lemonnier F, Thibault M, Couturier M, Auzepy P: Vitamin E deficiency, lipoperoxidation during adult respiratory distress syndrome. Crit Care Med 18:4-9, 1990.
    • (1990) Crit Care Med , vol.18 , pp. 4-9
    • Richard, C.1    Lemonnier, F.2    Thibault, M.3    Couturier, M.4    Auzepy, P.5
  • 19
    • 0024464651 scopus 로고
    • Increased hydrgen peroxide in the expired breath of patients with acute hypoxemic respiratory failure
    • Sznajder JI, Fraiman A, Hall JB, et al: Increased hydrgen peroxide in the expired breath of patients with acute hypoxemic respiratory failure. Chest 96:606-612, 1989.
    • (1989) Chest , vol.96 , pp. 606-612
    • Sznajder, J.I.1    Fraiman, A.2    Hall, J.B.3
  • 20
    • 0027400625 scopus 로고
    • Hydrogen peroxide in expired breath condensate of patients with acute respiratory failure and with ARDS
    • Keitzmann D, Kahl R, Muller M, Burchardi H, Kettler D: Hydrogen peroxide in expired breath condensate of patients with acute respiratory failure and with ARDS. Intensive Care Med 19:78-81, 1993.
    • (1993) Intensive Care Med , vol.19 , pp. 78-81
    • Keitzmann, D.1    Kahl, R.2    Muller, M.3    Burchardi, H.4    Kettler, D.5
  • 21
    • 0028158856 scopus 로고
    • Urine hydrogen peroxide during adult respiratory distress syndrome in patients with and without sepsis
    • Mathru M, Rooney MW, Dries DJ, Hirsch LJ, Barnes L, Tobin MJ: Urine hydrogen peroxide during adult respiratory distress syndrome in patients with and without sepsis. Chest 105:232-236, 1994.
    • (1994) Chest , vol.105 , pp. 232-236
    • Mathru, M.1    Rooney, M.W.2    Dries, D.J.3    Hirsch, L.J.4    Barnes, L.5    Tobin, M.J.6
  • 22
    • 0022633277 scopus 로고
    • Oxidant activity in expired breath of patients with adult respiratory distress syndrome
    • Baldwin SR, Simon RH, Grum CM, Ketai LH, Boxer LA, Devall LJ: Oxidant activity in expired breath of patients with adult respiratory distress syndrome. Lancet 1:114-116, 1986.
    • (1986) Lancet , vol.1 , pp. 114-116
    • Baldwin, S.R.1    Simon, R.H.2    Grum, C.M.3    Ketai, L.H.4    Boxer, L.A.5    Devall, L.J.6
  • 23
    • 0026048230 scopus 로고
    • Deficiency of alveolar fluid glutathione in patients with sepsis and the adult respiratory distress syndrome
    • Pacht ER, Timerman AP, Lykens MG, Merola AJ: Deficiency of alveolar fluid glutathione in patients with sepsis and the adult respiratory distress syndrome. Chest 100:1397-1403, 1991.
    • (1991) Chest , vol.100 , pp. 1397-1403
    • Pacht, E.R.1    Timerman, A.P.2    Lykens, M.G.3    Merola, A.J.4
  • 24
    • 0023919367 scopus 로고
    • Haematological, physiological and survival data in a porcine model of adult respiratory distress syndrome induced by endotoxaemia. Effects of treatment with N-acetylcysteine
    • Modig J, Sandin R: Haematological, physiological and survival data in a porcine model of adult respiratory distress syndrome induced by endotoxaemia. Effects of treatment with N-acetylcysteine. Acta Chir Scand 154: 169-177, 1988.
    • (1988) Acta Chir Scand , vol.154 , pp. 169-177
    • Modig, J.1    Sandin, R.2
  • 25
    • 0027144849 scopus 로고
    • Postinsult treatment with N-acetyl-L-cysteine decreases IL-1-induced neutrophil influx and lung leak in rats
    • Leff JA, Wilke CP, Hybertson BM, Shanley PF, Beehler CJ, Repine JE: Postinsult treatment with N-acetyl-L-cysteine decreases IL-1-induced neutrophil influx and lung leak in rats. Am J Physiol 265:L501-L506, 1993.
    • (1993) Am J Physiol , vol.265
    • Leff, J.A.1    Wilke, C.P.2    Hybertson, B.M.3    Shanley, P.F.4    Beehler, C.J.5    Repine, J.E.6
  • 26
    • 0021271892 scopus 로고
    • Effect of N-acetylcysteine on the pulmonary response to endotoxin in the awake sheep and upon in vitro granulocyte function
    • Bernard GR, Lucht WD, Niedermeyer ME, Snapper JR, Ogletree ML, Brigham KL: Effect of N-acetylcysteine on the pulmonary response to endotoxin in the awake sheep and upon in vitro granulocyte function. J Clin Invest 73:1772-1784, 1984.
    • (1984) J Clin Invest , vol.73 , pp. 1772-1784
    • Bernard, G.R.1    Lucht, W.D.2    Niedermeyer, M.E.3    Snapper, J.R.4    Ogletree, M.L.5    Brigham, K.L.6
  • 27
    • 0025219061 scopus 로고
    • Effects of N-acetylcysteine and terbutaline treatment on hemodynamics and regional albumin extravasation in porcine septic shock
    • Groeneveld AB, den Hollander W, Straub J, Nauta JJ, Thijs LG: Effects of N-acetylcysteine and terbutaline treatment on hemodynamics and regional albumin extravasation in porcine septic shock. Circ Shock 30:185-205, 1990.
    • (1990) Circ Shock , vol.30 , pp. 185-205
    • Groeneveld, A.B.1    Den Hollander, W.2    Straub, J.3    Nauta, J.J.4    Thijs, L.G.5
  • 28
    • 0023605006 scopus 로고
    • Dimethylthiourea attenuates endotoxin-induced acute respiratory failure in pigs
    • Olson NC, Anderson DL, Grizzle MK: Dimethylthiourea attenuates endotoxin-induced acute respiratory failure in pigs. J Appl Physiol 63:2426-2432, 1987.
    • (1987) J Appl Physiol , vol.63 , pp. 2426-2432
    • Olson, N.C.1    Anderson, D.L.2    Grizzle, M.K.3
  • 29
    • 0022481481 scopus 로고
    • Endotoxemia causes inreased lung tissue lipid peroxidation in unanesthetized sheep
    • Demling RH, Lalonde C, Jin L-J, Ryan P, Fox R: Endotoxemia causes inreased lung tissue lipid peroxidation in unanesthetized sheep. J Appl Physiol 60:2094-2100, 1986.
    • (1986) J Appl Physiol , vol.60 , pp. 2094-2100
    • Demling, R.H.1    Lalonde, C.2    Jin, L.-J.3    Ryan, P.4    Fox, R.5
  • 30
    • 0022371513 scopus 로고
    • Effect of hydroxyl radical scavenging on endotoxin-induced lung injury
    • Wong C, Fox R, Demling RH: Effect of hydroxyl radical scavenging on endotoxin-induced lung injury. Surgery 97:300-306, 1985.
    • (1985) Surgery , vol.97 , pp. 300-306
    • Wong, C.1    Fox, R.2    Demling, R.H.3
  • 31
    • 0025647323 scopus 로고
    • Failure of therapy with 2,3-dihydroxybenzoic acid to modify the course of sepsis-induced lung injury
    • Sharpe MD, Mustard RA, Finley RR, Rutledge FS, Sibbald WJ: Failure of therapy with 2,3-dihydroxybenzoic acid to modify the course of sepsis-induced lung injury. J Appl Physiol 69:1893-1902, 1990.
    • (1990) J Appl Physiol , vol.69 , pp. 1893-1902
    • Sharpe, M.D.1    Mustard, R.A.2    Finley, R.R.3    Rutledge, F.S.4    Sibbald, W.J.5
  • 32
    • 0026629468 scopus 로고
    • Antioxidant treatment with N-acetylcysteine during adult respiratory distress syndrome: A prospective, randomized, placebo-controlled study
    • Jepsen S, Herlevsen P, Knudsen P, Bud MI, Klausen NO: Antioxidant treatment with N-acetylcysteine during adult respiratory distress syndrome: A prospective, randomized, placebo-controlled study. Crit Care Med 20:918-923, 1992.
    • (1992) Crit Care Med , vol.20 , pp. 918-923
    • Jepsen, S.1    Herlevsen, P.2    Knudsen, P.3    Bud, M.I.4    Klausen, N.O.5
  • 33
    • 0028126051 scopus 로고
    • N-acetylcysteine enhances recovery from acute lung injury in man: A randomized, double-blind, placebo-controlled clinical study
    • Suter PM, Domenighetti G, Schaller MD, Laverriere MC, Ritz R, Perret C: N-acetylcysteine enhances recovery from acute lung injury in man: A randomized, double-blind, placebo-controlled clinical study. Chest 105: 190-194, 1994.
    • (1994) Chest , vol.105 , pp. 190-194
    • Suter, P.M.1    Domenighetti, G.2    Schaller, M.D.3    Laverriere, M.C.4    Ritz, R.5    Perret, C.6
  • 34
    • 0023758683 scopus 로고
    • Catalase prevents prostanoid release and lung lipid peroxidation after endotoxemia in sheep
    • Seekamp A, Lalonde C, Deguang Z, Demling R: Catalase prevents prostanoid release and lung lipid peroxidation after endotoxemia in sheep. J Appl Physiol 65:1210-1216, 1988.
    • (1988) J Appl Physiol , vol.65 , pp. 1210-1216
    • Seekamp, A.1    Lalonde, C.2    Deguang, Z.3    Demling, R.4
  • 35
    • 0023571251 scopus 로고
    • Effect of polyethylene glycol-superoxide dismutase and catalase on endotoxemia in pigs
    • Olson NC, Grizzle MK, Anderson DL: Effect of polyethylene glycol-superoxide dismutase and catalase on endotoxemia in pigs. J Appl Physiol 63:1526-1532, 1987.
    • (1987) J Appl Physiol , vol.63 , pp. 1526-1532
    • Olson, N.C.1    Grizzle, M.K.2    Anderson, D.L.3
  • 36
    • 0023723218 scopus 로고
    • Endotoxin causes hydrogen peroxide-induced lung lipid peroxidation and prostanoid production
    • Demling R, Lalonde C, Seekamp A, Fiore N: Endotoxin causes hydrogen peroxide-induced lung lipid peroxidation and prostanoid production. Arch Surg 123:1337-1341, 1988.
    • (1988) Arch Surg , vol.123 , pp. 1337-1341
    • Demling, R.1    Lalonde, C.2    Seekamp, A.3    Fiore, N.4
  • 37
    • 0023859115 scopus 로고
    • Effect of catalase on endotoxin-induced acute lung injury in unanesthetized sheep
    • Milligan SA, Hoeffel JM, Goldstein IM, Flick MR: Effect of catalase on endotoxin-induced acute lung injury in unanesthetized sheep. Am Rev Respir Dis 137:420-428, 1988.
    • (1988) Am Rev Respir Dis , vol.137 , pp. 420-428
    • Milligan, S.A.1    Hoeffel, J.M.2    Goldstein, I.M.3    Flick, M.R.4
  • 38
    • 0025231772 scopus 로고
    • Effects of recombinant human superoxide dismutase on increased lung vascular permeability and respiratory disorder in endotoxemic rats
    • Schneider J, Friderichs E, Heintze K, Flohe L: Effects of recombinant human superoxide dismutase on increased lung vascular permeability and respiratory disorder in endotoxemic rats. Circ Shock 30:97-106, 1990.
    • (1990) Circ Shock , vol.30 , pp. 97-106
    • Schneider, J.1    Friderichs, E.2    Heintze, K.3    Flohe, L.4
  • 39
    • 0023897692 scopus 로고
    • Evidence for lack of importance of oxygen free radicals in Escherichia coli endotoxemia in dogs
    • Novotny MJ, Laughlin MH, Adams HR: Evidence for lack of importance of oxygen free radicals in Escherichia coli endotoxemia in dogs. Am J Physiol 254:H954-H962, 1988.
    • (1988) Am J Physiol , vol.254
    • Novotny, M.J.1    Laughlin, M.H.2    Adams, H.R.3
  • 40
    • 0021864571 scopus 로고
    • Potentiation of lung vascular response to endotoxin by superoxide dismutase
    • Traber DL, Adams T Jr, Sziebert L, Stein M, Traber L: Potentiation of lung vascular response to endotoxin by superoxide dismutase. J Appl Physiol 58:1005-1009, 1985.
    • (1985) J Appl Physiol , vol.58 , pp. 1005-1009
    • Traber, D.L.1    Adams Jr., T.2    Sziebert, L.3    Stein, M.4    Traber, L.5
  • 41
    • 0020530692 scopus 로고
    • Inhibition of tumor promotion by a biomimetic SOD
    • Kensler TW, Bush DM, Kozumbo WJ: Inhibition of tumor promotion by a biomimetic SOD. Science 221:75-77, 1983.
    • (1983) Science , vol.221 , pp. 75-77
    • Kensler, T.W.1    Bush, D.M.2    Kozumbo, W.J.3
  • 42
    • 0025361210 scopus 로고
    • Anti-tumor promoting action of pthalic acid mono-n-butyl ester cupric salt, a biometic SOD
    • Yamamoto S, Nakadate ST, Aizu E, Kato R: Anti-tumor promoting action of pthalic acid mono-n-butyl ester cupric salt, a biometic SOD. Carcinogenesis 11:749-754, 1990.
    • (1990) Carcinogenesis , vol.11 , pp. 749-754
    • Yamamoto, S.1    Nakadate, S.T.2    Aizu, E.3    Kato, R.4
  • 44
    • 0023200797 scopus 로고
    • Characterization of superoxide dismutase activity based upon desferroxamine B and manganese (IV)
    • Darr D, Zarilla KA, Fridovich I: Characterization of superoxide dismutase activity based upon desferroxamine B and manganese (IV). Arch Biochem Biophys 258:351-355, 1987.
    • (1987) Arch Biochem Biophys , vol.258 , pp. 351-355
    • Darr, D.1    Zarilla, K.A.2    Fridovich, I.3
  • 45
    • 0027989826 scopus 로고
    • Stable Mn (III) porphyrins mimic superoxide dismutase: In vitro and substitute for it in vivo
    • Faulkner KM, Liochev SI, Fridovich I: Stable Mn (III) porphyrins mimic superoxide dismutase: In vitro and substitute for it in vivo. J Biol Chem 269:23741-23476, 1994.
    • (1994) J Biol Chem , vol.269 , pp. 23741-123476
    • Faulkner, K.M.1    Liochev, S.I.2    Fridovich, I.3
  • 46
    • 0028213439 scopus 로고
    • Manganese macrocyclic ligand complexes as mimics of superoxide dismutase
    • Riley DP, Weiss RH: Manganese macrocyclic ligand complexes as mimics of superoxide dismutase. J Am Chem Soc 116:387-388, 1994.
    • (1994) J Am Chem Soc , vol.116 , pp. 387-388
    • Riley, D.P.1    Weiss, R.H.2
  • 47
    • 0027943413 scopus 로고
    • Inhibition of in vivo myocardial ischemic and reperfusion injury by a synthetic manganese-based superoxide dismutase mimetic
    • Black SC, Schasteen CS, Weiss RH, Riley DP, Driscoll EM, Lucchesi BR: Inhibition of in vivo myocardial ischemic and reperfusion injury by a synthetic manganese-based superoxide dismutase mimetic. J Pharmacol Exp Ther 270:1208-1215, 1994.
    • (1994) J Pharmacol Exp Ther , vol.270 , pp. 1208-1215
    • Black, S.C.1    Schasteen, C.S.2    Weiss, R.H.3    Riley, D.P.4    Driscoll, E.M.5    Lucchesi, B.R.6
  • 48
    • 0001665764 scopus 로고
    • Dimanganese complexes of a septadentate ligand: Functional analogues of the manganese pseudocatalase
    • Mathur P, Crowder M, Dismukes GC: Dimanganese complexes of a septadentate ligand: Functional analogues of the manganese pseudocatalase. J Am Chem Soc 109:5227-5233, 1987.
    • (1987) J Am Chem Soc , vol.109 , pp. 5227-5233
    • Mathur, P.1    Crowder, M.2    Dismukes, G.C.3
  • 49
    • 0027966242 scopus 로고
    • Structural and functional models of the dimanganese catalase enzymes. 3. Kinetics and mechanism of hydrogen peroxide dismutation
    • Pessiki PJ, Dismukes GC: Structural and functional models of the dimanganese catalase enzymes. 3. Kinetics and mechanism of hydrogen peroxide dismutation. J Am Chem Soc 116:898-903, 1994.
    • (1994) J Am Chem Soc , vol.116 , pp. 898-903
    • Pessiki, P.J.1    Dismukes, G.C.2
  • 50
    • 0028318638 scopus 로고
    • Effects of EUK-8, a synthetic catalytic superoxide scavenger, on hypoxia- and acidosis-induced damage in hippocampal slices
    • Musleh W, Bruce A, Malfroy B, Baudry M: Effects of EUK-8, a synthetic catalytic superoxide scavenger, on hypoxia- and acidosis-induced damage in hippocampal slices. Neuropharm 33:929-934, 1994.
    • (1994) Neuropharm , vol.33 , pp. 929-934
    • Musleh, W.1    Bruce, A.2    Malfroy, B.3    Baudry, M.4
  • 51
    • 27644581538 scopus 로고    scopus 로고
    • Synthetic catalytic free radical scavengers useful as antioxidants for prevention and therapy of disease. United States patent number 5:403,834; 1995
    • Malfroy-Carmine, B, Baudry, M: Synthetic catalytic free radical scavengers useful as antioxidants for prevention and therapy of disease. United States patent number 5:403,834; 1995.
    • Malfroy-Carmine, B.1    Baudry, M.2
  • 52
    • 27644444611 scopus 로고
    • Effects of a salen-manganese complex, a SOD-mimic, in various models of neuronal pathology
    • abstract
    • Bruce A, Musleh W, Malfroy B, Baudry M: Effects of a salen-manganese complex, a SOD-mimic, in various models of neuronal pathology. Society for Neuroscience Abstracts 19:1680(abstract), 1994.
    • (1994) Society for Neuroscience Abstracts , vol.19 , pp. 1680
    • Bruce, A.1    Musleh, W.2    Malfroy, B.3    Baudry, M.4
  • 54
    • 0002515226 scopus 로고
    • Delayed treatment with EUK-8, a novel synthetic superoxide dismutase (SOD) and catalase (CAT) mimetic, ameliorates acute lung injury in endotoxemic pigs
    • Gonzalez PK, Zhuang J, Doctorow SR, Malfroy B, Smith M, Menconi MJ, Fink MP: Delayed treatment with EUK-8, a novel synthetic superoxide dismutase (SOD) and catalase (CAT) mimetic, ameliorates acute lung injury in endotoxemic pigs. Surg Forum 46:72-73, 1995.
    • (1995) Surg Forum , vol.46 , pp. 72-73
    • Gonzalez, P.K.1    Zhuang, J.2    Doctorow, S.R.3    Malfroy, B.4    Smith, M.5    Menconi, M.J.6    Fink, M.P.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.