메뉴 건너뛰기




Volumn 30, Issue 11, 2009, Pages 2040-2044

Animals models of MCH function and what they can tell us about its role in energy balance

Author keywords

Appetite; MCHR1; Melanin concentrating hormone; Obesity

Indexed keywords

GW 803430; MELANIN CONCENTRATING HORMONE; MELANIN CONCENTRATING HORMONE RECEPTOR 1; MELANIN CONCENTRATING HORMONE RECEPTOR 1 ANTAGONIST; SNAP 7491; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 1;

EID: 70349841277     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2009.05.002     Document Type: Review
Times cited : (42)

References (62)
  • 1
    • 0041419354 scopus 로고    scopus 로고
    • Identification of hypothalamic nuclei involved in the orexigenic effect of melanin-concentrating hormone
    • Abbott C.R., Kennedy A.R., Wren A.M., Rossi M., Murphy K.G., Seal L.J., et al. Identification of hypothalamic nuclei involved in the orexigenic effect of melanin-concentrating hormone. Endocrinology 144 (2003) 3943-3949
    • (2003) Endocrinology , vol.144 , pp. 3943-3949
    • Abbott, C.R.1    Kennedy, A.R.2    Wren, A.M.3    Rossi, M.4    Murphy, K.G.5    Seal, L.J.6
  • 2
    • 32544433424 scopus 로고    scopus 로고
    • Late-onset leanness in mice with targeted ablation of melanin concentrating hormone neurons
    • Alon T., and Friedman J.M. Late-onset leanness in mice with targeted ablation of melanin concentrating hormone neurons. J Neurosci 26 (2006) 389-397
    • (2006) J Neurosci , vol.26 , pp. 389-397
    • Alon, T.1    Friedman, J.M.2
  • 4
    • 0344604512 scopus 로고    scopus 로고
    • Identification of melanin concentrating hormone (MCH) as the natural ligand for the orphan somatostatin-like receptor 1 (SLC-1)
    • [In Process Citation]
    • Bachner D., Kreienkamp H., Weise C., Buck F., and Richter D. Identification of melanin concentrating hormone (MCH) as the natural ligand for the orphan somatostatin-like receptor 1 (SLC-1). FEBS Lett 457 (1999) 522-524 [In Process Citation]
    • (1999) FEBS Lett , vol.457 , pp. 522-524
    • Bachner, D.1    Kreienkamp, H.2    Weise, C.3    Buck, F.4    Richter, D.5
  • 5
    • 35448965210 scopus 로고    scopus 로고
    • Peptide ligands for the melanin-concentrating hormone (MCH) receptor 1
    • Bednarek M.A. Peptide ligands for the melanin-concentrating hormone (MCH) receptor 1. Curr Top Med Chem 7 (2007) 1425-1432
    • (2007) Curr Top Med Chem , vol.7 , pp. 1425-1432
    • Bednarek, M.A.1
  • 6
    • 0026766094 scopus 로고
    • The melanin-concentrating hormone system of the rat brain: an immuno- and hybridization histochemical characterization
    • Bittencourt J.C., Presse F., Arias C., Peto C., Vaughan J., Nahon J.L., et al. The melanin-concentrating hormone system of the rat brain: an immuno- and hybridization histochemical characterization. J Comp Neurol 319 (1992) 218-245
    • (1992) J Comp Neurol , vol.319 , pp. 218-245
    • Bittencourt, J.C.1    Presse, F.2    Arias, C.3    Peto, C.4    Vaughan, J.5    Nahon, J.L.6
  • 7
    • 33644785022 scopus 로고    scopus 로고
    • Melanin-concentrating hormone receptor 1 deficiency increases insulin sensitivity in obese leptin-deficient mice without affecting body weight
    • Bjursell M., Gerdin A.K., Ploj K., Svensson D., Svensson L., Oscarsson J., et al. Melanin-concentrating hormone receptor 1 deficiency increases insulin sensitivity in obese leptin-deficient mice without affecting body weight. Diabetes 55 (2006) 725-733
    • (2006) Diabetes , vol.55 , pp. 725-733
    • Bjursell, M.1    Gerdin, A.K.2    Ploj, K.3    Svensson, D.4    Svensson, L.5    Oscarsson, J.6
  • 9
    • 0036341292 scopus 로고    scopus 로고
    • Antidepressant, anxiolytic and anorectic effects of a melanin-concentrating hormone-1 receptor antagonist
    • Borowsky B., Durkin M.M., Ogozalek K., Marzabadi M.R., DeLeon J., Lagu B., et al. Antidepressant, anxiolytic and anorectic effects of a melanin-concentrating hormone-1 receptor antagonist. Nat Med 8 (2002) 825-830
    • (2002) Nat Med , vol.8 , pp. 825-830
    • Borowsky, B.1    Durkin, M.M.2    Ogozalek, K.3    Marzabadi, M.R.4    DeLeon, J.5    Lagu, B.6
  • 10
    • 37049035734 scopus 로고    scopus 로고
    • Microinjections of melanin concentrating hormone into the nucleus tractus solitarius of the rat elicit depressor and bradycardic responses
    • Brown S.N., Chitravanshi V.C., Kawabe K., and Sapru H.N. Microinjections of melanin concentrating hormone into the nucleus tractus solitarius of the rat elicit depressor and bradycardic responses. Neuroscience 150 (2007) 796-806
    • (2007) Neuroscience , vol.150 , pp. 796-806
    • Brown, S.N.1    Chitravanshi, V.C.2    Kawabe, K.3    Sapru, H.N.4
  • 11
    • 0033566128 scopus 로고    scopus 로고
    • Melanin-concentrating hormone is the cognate ligand for the orphan G-protein-coupled receptor SLC-1
    • Chambers J., Ames R.S., Bergsma D., Muir A., Fitzgerald L.R., Hervieu G., et al. Melanin-concentrating hormone is the cognate ligand for the orphan G-protein-coupled receptor SLC-1. Nature 400 (1999) 261-265
    • (1999) Nature , vol.400 , pp. 261-265
    • Chambers, J.1    Ames, R.S.2    Bergsma, D.3    Muir, A.4    Fitzgerald, L.R.5    Hervieu, G.6
  • 12
    • 18444375866 scopus 로고    scopus 로고
    • Targeted disruption of the melanin-concentrating hormone receptor-1 results in hyperphagia and resistance to diet-induced obesity
    • Chen Y., Hu C., Hsu C.K., Zhang Q., Bi C., Asnicar M., et al. Targeted disruption of the melanin-concentrating hormone receptor-1 results in hyperphagia and resistance to diet-induced obesity. Endocrinology 143 (2002) 2469-2477
    • (2002) Endocrinology , vol.143 , pp. 2469-2477
    • Chen, Y.1    Hu, C.2    Hsu, C.K.3    Zhang, Q.4    Bi, C.5    Asnicar, M.6
  • 14
    • 0036797774 scopus 로고    scopus 로고
    • Acute and chronic administration of melanin-concentrating hormone enhances food intake and body weight in Wistar and Sprague-Dawley rats
    • Della-Zuana O., Presse F., Ortola C., Duhault J., Nahon J.L., and Levens N. Acute and chronic administration of melanin-concentrating hormone enhances food intake and body weight in Wistar and Sprague-Dawley rats. Int J Obes Relat Metab Disord 26 (2002) 1289-1295
    • (2002) Int J Obes Relat Metab Disord , vol.26 , pp. 1289-1295
    • Della-Zuana, O.1    Presse, F.2    Ortola, C.3    Duhault, J.4    Nahon, J.L.5    Levens, N.6
  • 15
    • 21644462922 scopus 로고    scopus 로고
    • Central administration of melanin-concentrating hormone increases alcohol and sucrose/quinine intake in rats
    • Duncan E.A., Proulx K., and Woods S.C. Central administration of melanin-concentrating hormone increases alcohol and sucrose/quinine intake in rats. Alcohol Clin Exp Res 29 (2005) 958-964
    • (2005) Alcohol Clin Exp Res , vol.29 , pp. 958-964
    • Duncan, E.A.1    Proulx, K.2    Woods, S.C.3
  • 16
    • 20144362544 scopus 로고    scopus 로고
    • The hypothalamic neuropeptide melanin-concentrating hormone acts in the nucleus accumbens to modulate feeding behavior and forced-swim performance
    • Georgescu D., Sears R.M., Hommel J.D., Barrot M., Bolanos C.A., Marsh D.J., et al. The hypothalamic neuropeptide melanin-concentrating hormone acts in the nucleus accumbens to modulate feeding behavior and forced-swim performance. J Neurosci 25 (2005) 2933-2940
    • (2005) J Neurosci , vol.25 , pp. 2933-2940
    • Georgescu, D.1    Sears, R.M.2    Hommel, J.D.3    Barrot, M.4    Bolanos, C.A.5    Marsh, D.J.6
  • 18
    • 64149125631 scopus 로고    scopus 로고
    • Effects of intracerebroventricular and intra-accumbens Melanin-Concentrating Hormone agonism on food intake and energy expenditure
    • Guesdon B., Paradis E., Samson P., and Richard D. Effects of intracerebroventricular and intra-accumbens Melanin-Concentrating Hormone agonism on food intake and energy expenditure. Am J Physiol Regul Integr Comp Physiol (2009)
    • (2009) Am J Physiol Regul Integr Comp Physiol
    • Guesdon, B.1    Paradis, E.2    Samson, P.3    Richard, D.4
  • 19
    • 0034005858 scopus 로고    scopus 로고
    • The distribution of the mRNA and protein products of the melanin-concentrating hormone (MCH) receptor gene, slc-1, in the central nervous system of the rat
    • Hervieu G.J., Cluderay J.E., Harrison D., Meakin J., Maycox P., Nasir S., et al. The distribution of the mRNA and protein products of the melanin-concentrating hormone (MCH) receptor gene, slc-1, in the central nervous system of the rat. Eur J Neurosci 12 (2000) 1194-1216
    • (2000) Eur J Neurosci , vol.12 , pp. 1194-1216
    • Hervieu, G.J.1    Cluderay, J.E.2    Harrison, D.3    Meakin, J.4    Maycox, P.5    Nasir, S.6
  • 21
    • 33644778822 scopus 로고    scopus 로고
    • MCH-/- mice are resistant to aging-associated increases in body weight and insulin resistance
    • Jeon J.Y., Bradley R.L., Kokkotou E.G., Marino F.E., Wang X., Pissios P., et al. MCH-/- mice are resistant to aging-associated increases in body weight and insulin resistance. Diabetes 55 (2006) 428-434
    • (2006) Diabetes , vol.55 , pp. 428-434
    • Jeon, J.Y.1    Bradley, R.L.2    Kokkotou, E.G.3    Marino, F.E.4    Wang, X.5    Pissios, P.6
  • 22
    • 0020643565 scopus 로고
    • Characterization of melanin-concentrating hormone in chum salmon pituitaries
    • Kawauchi H., Kawazoe I., Tsubokawa M., Kishida M., and Baker B.I. Characterization of melanin-concentrating hormone in chum salmon pituitaries. Nature 305 (1983) 321-323
    • (1983) Nature , vol.305 , pp. 321-323
    • Kawauchi, H.1    Kawazoe, I.2    Tsubokawa, M.3    Kishida, M.4    Baker, B.I.5
  • 23
    • 0034991515 scopus 로고    scopus 로고
    • Melanin-concentrating hormone (MCH) suppresses thyroid stimulating hormone (TSH) release, in vivo and in vitro, via the hypothalamus and the pituitary
    • Kennedy A.R., Todd J.F., Stanley S.A., Abbott C.R., Small C.J., Ghatei M.A., et al. Melanin-concentrating hormone (MCH) suppresses thyroid stimulating hormone (TSH) release, in vivo and in vitro, via the hypothalamus and the pituitary. Endocrinology 142 (2001) 3265-3268
    • (2001) Endocrinology , vol.142 , pp. 3265-3268
    • Kennedy, A.R.1    Todd, J.F.2    Stanley, S.A.3    Abbott, C.R.4    Small, C.J.5    Ghatei, M.A.6
  • 25
    • 33645387936 scopus 로고    scopus 로고
    • Effects of a selective melanin-concentrating hormone 1 receptor antagonist on food intake and energy homeostasis in diet-induced obese mice
    • Kowalski T.J., Spar B.D., Weig B., Farley C., Cook J., Ghibaudi L., et al. Effects of a selective melanin-concentrating hormone 1 receptor antagonist on food intake and energy homeostasis in diet-induced obese mice. Eur J Pharmacol 535 (2006) 182-191
    • (2006) Eur J Pharmacol , vol.535 , pp. 182-191
    • Kowalski, T.J.1    Spar, B.D.2    Weig, B.3    Farley, C.4    Cook, J.5    Ghibaudi, L.6
  • 26
    • 0033194242 scopus 로고    scopus 로고
    • The receptor for the orexigenic peptide melanin-concentrating hormone is a G-protein-coupled receptor
    • Lembo P.M., Grazzini E., Cao J., Hubatsch D.A., Pelletier M., Hoffert C., et al. The receptor for the orexigenic peptide melanin-concentrating hormone is a G-protein-coupled receptor. Nat Cell Biol 1 (1999) 267-271
    • (1999) Nat Cell Biol , vol.1 , pp. 267-271
    • Lembo, P.M.1    Grazzini, E.2    Cao, J.3    Hubatsch, D.A.4    Pelletier, M.5    Hoffert, C.6
  • 27
    • 0021732102 scopus 로고
    • Neuropeptide Y: a potent inducer of consummatory behavior in rats
    • Levine A.S., and Morley J.E. Neuropeptide Y: a potent inducer of consummatory behavior in rats. Peptides 5 (1984) 1025-1029
    • (1984) Peptides , vol.5 , pp. 1025-1029
    • Levine, A.S.1    Morley, J.E.2
  • 28
    • 0035134670 scopus 로고    scopus 로고
    • Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance
    • Ludwig D.S., Tritos N.A., Mastaitis J.W., Kulkarni R., Kokkotou E., Elmquist J., et al. Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance. J Clin Invest 107 (2001) 379-386
    • (2001) J Clin Invest , vol.107 , pp. 379-386
    • Ludwig, D.S.1    Tritos, N.A.2    Mastaitis, J.W.3    Kulkarni, R.4    Kokkotou, E.5    Elmquist, J.6
  • 29
    • 27344431720 scopus 로고    scopus 로고
    • NPY/AgRP neurons are essential for feeding in adult mice but can be ablated in neonates
    • Luquet S., Perez F.A., Hnasko T.S., and Palmiter R.D. NPY/AgRP neurons are essential for feeding in adult mice but can be ablated in neonates. Science 310 (2005) 683-685
    • (2005) Science , vol.310 , pp. 683-685
    • Luquet, S.1    Perez, F.A.2    Hnasko, T.S.3    Palmiter, R.D.4
  • 30
    • 34547476684 scopus 로고    scopus 로고
    • Anti-obesity effects of small molecule melanin-concentrating hormone receptor 1 (MCHR1) antagonists
    • Luthin D.R. Anti-obesity effects of small molecule melanin-concentrating hormone receptor 1 (MCHR1) antagonists. Life Sci 81 (2007) 423-440
    • (2007) Life Sci , vol.81 , pp. 423-440
    • Luthin, D.R.1
  • 31
    • 33750434862 scopus 로고    scopus 로고
    • Optimization of chromone-2-carboxamide melanin concentrating hormone receptor 1 antagonists: assessment of potency, efficacy, and cardiovascular safety
    • Lynch J.K., Freeman J.C., Judd A.S., Iyengar R., Mulhern M., Zhao G., et al. Optimization of chromone-2-carboxamide melanin concentrating hormone receptor 1 antagonists: assessment of potency, efficacy, and cardiovascular safety. J Med Chem 49 (2006) 6569-6584
    • (2006) J Med Chem , vol.49 , pp. 6569-6584
    • Lynch, J.K.1    Freeman, J.C.2    Judd, A.S.3    Iyengar, R.4    Mulhern, M.5    Zhao, G.6
  • 32
    • 0037022667 scopus 로고    scopus 로고
    • Melanin-concentrating hormone 1 receptor-deficient mice are lean, hyperactive, and hyperphagic and have altered metabolism
    • Marsh D.J., Weingarth D.T., Novi D.E., Chen H.Y., Trumbauer M.E., Chen A.S., et al. Melanin-concentrating hormone 1 receptor-deficient mice are lean, hyperactive, and hyperphagic and have altered metabolism. Proc Natl Acad Sci USA 99 (2002) 3240-3245
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 3240-3245
    • Marsh, D.J.1    Weingarth, D.T.2    Novi, D.E.3    Chen, H.Y.4    Trumbauer, M.E.5    Chen, A.S.6
  • 33
    • 22144466234 scopus 로고    scopus 로고
    • Antiobesity effect of a melanin-concentrating hormone 1 receptor antagonist in diet-induced obese mice
    • Mashiko S., Ishihara A., Gomori A., Moriya R., Ito M., Iwaasa H., et al. Antiobesity effect of a melanin-concentrating hormone 1 receptor antagonist in diet-induced obese mice. Endocrinology 146 (2005) 3080-3086
    • (2005) Endocrinology , vol.146 , pp. 3080-3086
    • Mashiko, S.1    Ishihara, A.2    Gomori, A.3    Moriya, R.4    Ito, M.5    Iwaasa, H.6
  • 34
    • 33746126228 scopus 로고    scopus 로고
    • Recent advances in the discovery of melanin-concentrating hormone receptor antagonists
    • McBriar M.D. Recent advances in the discovery of melanin-concentrating hormone receptor antagonists. Curr Opin Drug Discov Devel 9 (2006) 496-508
    • (2006) Curr Opin Drug Discov Devel , vol.9 , pp. 496-508
    • McBriar, M.D.1
  • 35
    • 33846783263 scopus 로고    scopus 로고
    • Cardiovascular effects of melanin-concentrating hormone
    • Messina M.M., and Overton J.M. Cardiovascular effects of melanin-concentrating hormone. Regul Pept 139 (2007) 23-30
    • (2007) Regul Pept , vol.139 , pp. 23-30
    • Messina, M.M.1    Overton, J.M.2
  • 36
    • 27744480632 scopus 로고    scopus 로고
    • Effects of MCH and a MCH1-receptor antagonist on (palatable) food and water intake
    • Morens C., Norregaard P., Receveur J.M., van Dijk G., and Scheurink A.J. Effects of MCH and a MCH1-receptor antagonist on (palatable) food and water intake. Brain Res 1062 (2005) 32-38
    • (2005) Brain Res , vol.1062 , pp. 32-38
    • Morens, C.1    Norregaard, P.2    Receveur, J.M.3    van Dijk, G.4    Scheurink, A.J.5
  • 37
    • 0028153289 scopus 로고
    • The melanin-concentrating hormone: from the peptide to the gene
    • Nahon J.L. The melanin-concentrating hormone: from the peptide to the gene. Crit Rev Neurobiol 8 (1994) 221-262
    • (1994) Crit Rev Neurobiol , vol.8 , pp. 221-262
    • Nahon, J.L.1
  • 38
    • 33746151322 scopus 로고    scopus 로고
    • The melanocortins and melanin-concentrating hormone in the central regulation of feeding behavior and energy homeostasis
    • [53-5 discussion]
    • Nahon J.L. The melanocortins and melanin-concentrating hormone in the central regulation of feeding behavior and energy homeostasis. C R Biol 329 (2006) 623-638 [53-5 discussion]
    • (2006) C R Biol , vol.329 , pp. 623-638
    • Nahon, J.L.1
  • 39
    • 0242552065 scopus 로고    scopus 로고
    • Hypothalamic melanin-concentrating hormone is induced by cold exposure and participates in the control of energy expenditure in rats
    • Pereira-da-Silva M., Torsoni M.A., Nourani H.V., Augusto V.D., Souza C.T., Gasparetti A.L., et al. Hypothalamic melanin-concentrating hormone is induced by cold exposure and participates in the control of energy expenditure in rats. Endocrinology 144 (2003) 4831-4840
    • (2003) Endocrinology , vol.144 , pp. 4831-4840
    • Pereira-da-Silva, M.1    Torsoni, M.A.2    Nourani, H.V.3    Augusto, V.D.4    Souza, C.T.5    Gasparetti, A.L.6
  • 40
    • 33750076072 scopus 로고    scopus 로고
    • Expanding the scales: The multiple roles of MCH in regulating energy balance and other biological functions
    • Pissios P., Bradley R.L., and Maratos-Flier E. Expanding the scales: The multiple roles of MCH in regulating energy balance and other biological functions. Endocr Rev 27 (2006) 606-620
    • (2006) Endocr Rev , vol.27 , pp. 606-620
    • Pissios, P.1    Bradley, R.L.2    Maratos-Flier, E.3
  • 42
    • 33847030703 scopus 로고    scopus 로고
    • Melanin concentrating hormone is a novel regulator of islet function and growth
    • Pissios P., Ozcan U., Kokkotou E., Okada T., Liew C.W., Liu S., et al. Melanin concentrating hormone is a novel regulator of islet function and growth. Diabetes 56 (2007) 311-319
    • (2007) Diabetes , vol.56 , pp. 311-319
    • Pissios, P.1    Ozcan, U.2    Kokkotou, E.3    Okada, T.4    Liew, C.W.5    Liu, S.6
  • 43
    • 13344279395 scopus 로고    scopus 로고
    • A role for melanin-concentrating hormone in the central regulation of feeding behaviour
    • Qu D., Ludwig D.S., Gammeltoft S., Piper M., Pelleymounter M.A., Cullen M.J., et al. A role for melanin-concentrating hormone in the central regulation of feeding behaviour. Nature 380 (1996) 243-247
    • (1996) Nature , vol.380 , pp. 243-247
    • Qu, D.1    Ludwig, D.S.2    Gammeltoft, S.3    Piper, M.4    Pelleymounter, M.A.5    Cullen, M.J.6
  • 44
    • 0031023301 scopus 로고    scopus 로고
    • Melanin-concentrating hormone acutely stimulates feeding, but chronic administration has no effect on body weight
    • Rossi M., Choi S.J., O'Shea D., Miyoshi T., Ghatei M.A., and Bloom S.R. Melanin-concentrating hormone acutely stimulates feeding, but chronic administration has no effect on body weight. Endocrinology 138 (1997) 351-355
    • (1997) Endocrinology , vol.138 , pp. 351-355
    • Rossi, M.1    Choi, S.J.2    O'Shea, D.3    Miyoshi, T.4    Ghatei, M.A.5    Bloom, S.R.6
  • 45
    • 43849103769 scopus 로고    scopus 로고
    • The melanin-concentrating hormone system and its physiological functions
    • Saito Y., and Nagasaki H. The melanin-concentrating hormone system and its physiological functions. Results Probl Cell Differ 46 (2008) 159-179
    • (2008) Results Probl Cell Differ , vol.46 , pp. 159-179
    • Saito, Y.1    Nagasaki, H.2
  • 46
    • 0033566084 scopus 로고    scopus 로고
    • Molecular characterization of the melanin-concentrating hormone receptor
    • Saito Y., Nothacker H.-P., Wang Z., Lin S.H.S., Leslie F., and Civelli O. Molecular characterization of the melanin-concentrating hormone receptor. Nature 400 (1999) 265-269
    • (1999) Nature , vol.400 , pp. 265-269
    • Saito, Y.1    Nothacker, H.-P.2    Wang, Z.3    Lin, S.H.S.4    Leslie, F.5    Civelli, O.6
  • 48
    • 0030919781 scopus 로고    scopus 로고
    • Melanin-concentrating hormone (MCH) antagonizes the effects of alpha- MSH and neuropeptide E-I on grooming and locomotor activities in the rat
    • Sanchez M., Baker B.I., and Celis M. Melanin-concentrating hormone (MCH) antagonizes the effects of alpha- MSH and neuropeptide E-I on grooming and locomotor activities in the rat. Peptides 18 (1997) 393-396
    • (1997) Peptides , vol.18 , pp. 393-396
    • Sanchez, M.1    Baker, B.I.2    Celis, M.3
  • 51
    • 0032542294 scopus 로고    scopus 로고
    • Mice lacking melanin-concentrating hormone are hypophagic and lean
    • Shimada M., Tritos N.A., Lowell B.B., Flier J.S., and Maratos-Flier E. Mice lacking melanin-concentrating hormone are hypophagic and lean. Nature 396 (1998) 670-674
    • (1998) Nature , vol.396 , pp. 670-674
    • Shimada, M.1    Tritos, N.A.2    Lowell, B.B.3    Flier, J.S.4    Maratos-Flier, E.5
  • 52
    • 0033546693 scopus 로고    scopus 로고
    • Isolation and identification of melanin-concentrating hormone as the endogenous ligand of the SLC-1 receptor
    • Shimomura Y., Mori M., Sugo T., Ishibashi Y., Abe M., Kurokawa T., et al. Isolation and identification of melanin-concentrating hormone as the endogenous ligand of the SLC-1 receptor. Biochem. Biophys. Res. Commun. 261 (1999) 622-626
    • (1999) Biochem. Biophys. Res. Commun. , vol.261 , pp. 622-626
    • Shimomura, Y.1    Mori, M.2    Sugo, T.3    Ishibashi, Y.4    Abe, M.5    Kurokawa, T.6
  • 53
    • 37549040551 scopus 로고    scopus 로고
    • Behavioral and biochemical responses to d-amphetamine in MCH1 receptor knockout mice
    • Smith D.G., Qi H., Svenningsson P., Wade M., Davis R.J., Gehlert D.R., et al. Behavioral and biochemical responses to d-amphetamine in MCH1 receptor knockout mice. Synapse 62 (2008) 128-136
    • (2008) Synapse , vol.62 , pp. 128-136
    • Smith, D.G.1    Qi, H.2    Svenningsson, P.3    Wade, M.4    Davis, R.J.5    Gehlert, D.R.6
  • 54
    • 12844265880 scopus 로고    scopus 로고
    • Mesolimbic dopamine super-sensitivity in melanin-concentrating hormone-1 receptor-deficient mice
    • Smith D.G., Tzavara E.T., Shaw J., Luecke S., Wade M., Davis R., et al. Mesolimbic dopamine super-sensitivity in melanin-concentrating hormone-1 receptor-deficient mice. J Neurosci 25 (2005) 914-922
    • (2005) J Neurosci , vol.25 , pp. 914-922
    • Smith, D.G.1    Tzavara, E.T.2    Shaw, J.3    Luecke, S.4    Wade, M.5    Davis, R.6
  • 55
    • 0021713735 scopus 로고
    • Neuropeptide Y: stimulation of feeding and drinking by injection into the paraventricular nucleus
    • Stanley B.G., and Leibowitz S.F. Neuropeptide Y: stimulation of feeding and drinking by injection into the paraventricular nucleus. Life Sci 35 (1984) 2635-2642
    • (1984) Life Sci , vol.35 , pp. 2635-2642
    • Stanley, B.G.1    Leibowitz, S.F.2
  • 56
    • 0034726721 scopus 로고    scopus 로고
    • Expression of melanin-concentrating hormone receptors in insulin-producing cells: MCH stimulates insulin release in RINm5F and CRI-G1 cell-lines
    • Tadayyon M., Welters H.J., Haynes A.C., Cluderay J.E., and Hervieu G. Expression of melanin-concentrating hormone receptors in insulin-producing cells: MCH stimulates insulin release in RINm5F and CRI-G1 cell-lines. Biochem Biophy Res Commun 275 (2000) 709-712
    • (2000) Biochem Biophy Res Commun , vol.275 , pp. 709-712
    • Tadayyon, M.1    Welters, H.J.2    Haynes, A.C.3    Cluderay, J.E.4    Hervieu, G.5
  • 57
    • 18344363180 scopus 로고    scopus 로고
    • T-226296: a novel, orally active and selective melanin-concentrating hormone receptor antagonist
    • Takekawa S., Asami A., Ishihara Y., Terauchi J., Kato K., Shimomura Y., et al. T-226296: a novel, orally active and selective melanin-concentrating hormone receptor antagonist. Eur J Pharmacol 438 (2002) 129-135
    • (2002) Eur J Pharmacol , vol.438 , pp. 129-135
    • Takekawa, S.1    Asami, A.2    Ishihara, Y.3    Terauchi, J.4    Kato, K.5    Shimomura, Y.6
  • 58
    • 0036271227 scopus 로고    scopus 로고
    • Melanin-concentrating hormone receptor subtypes 1 and 2: species-specific gene expression
    • Tan C.P., Sano H., Iwaasa H., Pan J., Sailer A.W., Hreniuk D.L., et al. Melanin-concentrating hormone receptor subtypes 1 and 2: species-specific gene expression. Genomics 79 (2002) 785-792
    • (2002) Genomics , vol.79 , pp. 785-792
    • Tan, C.P.1    Sano, H.2    Iwaasa, H.3    Pan, J.4    Sailer, A.W.5    Hreniuk, D.L.6
  • 59
    • 33845391566 scopus 로고    scopus 로고
    • Potent, selective, and orally efficacious antagonists of melanin-concentrating hormone receptor 1
    • Tavares F.X., Al-Barazanji K.A., Bigham E.C., Bishop M.J., Britt C.S., Carlton D.L., et al. Potent, selective, and orally efficacious antagonists of melanin-concentrating hormone receptor 1. J Med Chem 49 (2006) 7095-7107
    • (2006) J Med Chem , vol.49 , pp. 7095-7107
    • Tavares, F.X.1    Al-Barazanji, K.A.2    Bigham, E.C.3    Bishop, M.J.4    Britt, C.S.5    Carlton, D.L.6
  • 60
    • 33750104208 scopus 로고    scopus 로고
    • Mice lacking the melanin-concentrating hormone receptor-1 exhibit an atypical psychomotor susceptibility to cocaine and no conditioned cocaine response
    • Tyhon A., Adamantidis A., Foidart A., Grisar T., Lakaye B., and Tirelli E. Mice lacking the melanin-concentrating hormone receptor-1 exhibit an atypical psychomotor susceptibility to cocaine and no conditioned cocaine response. Behav Brain Res 173 (2006) 94-103
    • (2006) Behav Brain Res , vol.173 , pp. 94-103
    • Tyhon, A.1    Adamantidis, A.2    Foidart, A.3    Grisar, T.4    Lakaye, B.5    Tirelli, E.6
  • 61
    • 24944511205 scopus 로고    scopus 로고
    • Melanin concentrating hormone innervation of caudal brainstem areas involved in gastrointestinal functions and energy balance
    • Zheng H., Patterson L.M., Morrison C., Banfield B.W., Randall J.A., Browning K.N., et al. Melanin concentrating hormone innervation of caudal brainstem areas involved in gastrointestinal functions and energy balance. Neuroscience 135 (2005) 611-625
    • (2005) Neuroscience , vol.135 , pp. 611-625
    • Zheng, H.1    Patterson, L.M.2    Morrison, C.3    Banfield, B.W.4    Randall, J.A.5    Browning, K.N.6
  • 62
    • 8444239400 scopus 로고    scopus 로고
    • Enhanced running wheel activity of both Mch1r- and Pmch-deficient mice
    • Zhou D., Shen Z., Strack A.M., Marsh D.J., and Shearman L.P. Enhanced running wheel activity of both Mch1r- and Pmch-deficient mice. Regul Pept 124 (2005) 53-63
    • (2005) Regul Pept , vol.124 , pp. 53-63
    • Zhou, D.1    Shen, Z.2    Strack, A.M.3    Marsh, D.J.4    Shearman, L.P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.