Effects of a selective melanin-concentrating hormone 1 receptor antagonist on food intake and energy homeostasis in diet-induced obese mice

European Journal of Pharmacology

Volumn 535, Issue 1-3, 2006, Pages 182-191

  Kowalski, Timothy J ^a   Spar, Brian D ^a   Weig, Blair ^a   Farley, Constance ^a   Cook, John ^a   Ghibaudi, Lorraine ^a   Fried, Steve ^a   O'Neill, Kim ^a   Del Vecchio, Robert A ^a   McBriar, Mark ^a   Guzik, Henry ^a   Clader, John ^a   Hawes, Brian E ^a   Hwa, Joyce ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Indirect calorimetry; Melanin concentrating hormone; Obesity; Receptor antagonist

Indexed keywords

COCAINE AND AMPHETAMINE REGULATED TRANSCRIPT PEPTIDE; FATTY ACID; GALANIN; LEPTIN; MELANIN CONCENTRATING HORMONE; N [5 (4 CYANOPHENYL)BICYCLO[3.1.0]HEX 2 YL] N' [4 FLUORO 3 TRIFLUOROMETHYLPHENYL] N [3 (4 METHYL 1 PIPERAZINYL)PROPYL]UREA; OREXIN; PEPTIDE HORMONE ANTAGONIST; SIBUTRAMINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DIET; DOSE RESPONSE; DRUG RECEPTOR BINDING; ENERGY BALANCE; ENERGY EXPENDITURE; EX VIVO STUDY; FOOD INTAKE; GENE EXPRESSION; HYPOPHAGIA; IN VITRO STUDY; MALE; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; WEIGHT REDUCTION;

ADIPOSE TISSUE; ADMINISTRATION, ORAL; ANIMALS; BINDING, COMPETITIVE; BODY WEIGHT; BRAIN; CHO CELLS; CRICETINAE; CRICETULUS; DIETARY FATS; DOSE-RESPONSE RELATIONSHIP, DRUG; EATING; ENERGY METABOLISM; FATTY ACIDS, NONESTERIFIED; FEMALE; GALANIN; GENE EXPRESSION; HOMEOSTASIS; HYPOTHALAMIC HORMONES; HYPOTHALAMUS; INSULIN; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; IODINE RADIOISOTOPES; LEPTIN; MALE; MELANINS; MICE; MICE, INBRED C57BL; MICE, OBESE; NEUROPEPTIDE Y; NEUROPEPTIDES; NITRILES; OBESITY; OLIGOPEPTIDES; PIPERAZINES; PITUITARY HORMONES; PROTEIN BINDING; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NEUROPEPTIDE; RECEPTORS, SOMATOSTATIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRIGLYCERIDES; UREA;

EID: 33645387936     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2006.01.062     Document Type: Article

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