Central administration of melanin-concentrating hormone increases alcohol and sucrose/quinine intake in rats

Alcoholism: Clinical and Experimental Research

Volumn 29, Issue 6, 2005, Pages 958-964

  Duncan, Elizabeth A ^a,b   Proulx, Karine ^a   Woods, Stephen C ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b Genome Research Institute   (United States)

Author keywords

Alcohol; Anxiety; Melanin concentrating hormone; Sucrose

Indexed keywords

ALCOHOL; MELANIN CONCENTRATING HORMONE; NEUROPEPTIDE Y; SODIUM CHLORIDE;

ALCOHOL CONSUMPTION; ANIMAL EXPERIMENT; ANXIETY; ARTICLE; CALORIC INTAKE; CONTROLLED STUDY; DOSE RESPONSE; DRINKING BEHAVIOR; DRUG EFFECT; ENERGY BALANCE; FLUID BALANCE; HOMEOSTASIS; MALE; MAZE TEST; NONHUMAN; PRIORITY JOURNAL; RAT; REWARD; SUGAR INTAKE;

ALCOHOL DRINKING; ANIMALS; BEHAVIOR, ANIMAL; DRINKING; ENERGY METABOLISM; ETHANOL; HYPOTHALAMIC HORMONES; INJECTIONS, INTRAVENTRICULAR; MALE; MAZE LEARNING; MELANINS; PITUITARY HORMONES; QUININE; RATS; RATS, LONG-EVANS; REWARD; SELF ADMINISTRATION; SUCROSE;

CINCHONA PUBESCENS;

EID: 21644462922     PISSN: 01456008     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ALC.0000167741.42353.10     Document Type: Article

References (70)

1. American Psychiatric Association (1994) Diagnostic and Statistical Manual of Mental Disorders, 4th ed.: DSM-IV, American Psychiatric Publishing, Inc., Washington.
2. Avena NM, Hoebel BG (2003a) Amphetamine-sensitized rats show sugar-induced hyperactivity (cross-sensitization) and sugar hyperphagia. Pharmacol Biochem Behav 74:635-639.
3. Avena NM, Hoebel BG (2003b) A diet promoting sugar dependency causes behavioral cross-sensitization to a low dose of amphetamine. Neuroscience 122:17-20.
4. Badia-Elder NE, Stewart RB, Powrozek TA, Roy KF, Murphy JM, Li TK (2001) Effect of neuropeptide Y (NPY) on oral ethanol intake in Wistar, alcohol-preferring (P), and -nonpreferring (NP) rats. Alcohol Clin Exp Res 25:386-390.
5. Bell SM, Reynolds JG, Thiele TE, Gan J, Figlewicz DP, Woods SC (1998) Effects of third intracerebroventricular injections of corticotropin-releasing factor (CRF) on ethanol drinking and food intake. Psychopharmacology (Berl) 139:128-35.
6. Blednov YA, Walker D, Harris RA (2004) Blockade of the leptin-sensitive pathway markedly reduces alcohol consumption in mice. Alcohol Clin Exp Res 28(11):1683-1692.
7. Borowsky B, Durkin MM, Ogozalek K, Marzabadi MR, DeLeon J, Lagu B, Heurich R, Lichtblau H, Shaposhnik Z, Daniewska I, Blackburn TP, Branchek TA, Gerald C, Vaysse PJ, Forray C (2002) Antidepressant, anxiolytic and anorectic effects of a melanin-concentrating hormone-1 receptor antagonist. Nat Med 8:825-830.
8. Buemann B, Astrup A (2001) How does the body deal with energy from alcohol? Nutrition 17:638-641.
9. Cabeza de Vaca S, Carr KD (1998) Food restriction enhances the central rewarding effect of abused drugs. J Neurosci 18:7502-7510.
10. Caton SJ, Ball M, Ahern A, Hetherington MM (2004) Dose-dependent effects of alcohol on appetite and food intake. Physiol Behav 81:51-58.
11. Clegg DJ, Air EL, Benoit SC, Sakai RS, Seeley RJ, Woods SC (2003) Intraventricular melanin-concentrating hormone stimulates water intake independent of food intake. Am J Physiol Regul Integr Comp Physiol 284:R494-R499.
12. Colantuoni C, Rada P, McCarthy J, Patten C, Avena NM, Chadeayne A, Hoebel BG (2002) Evidence that intermittent, excessive sugar intake causes endogenous opioid dependence. Obes Res 10:478-488.
13. Colantuoni C, Schwenker J, McCarthy J, Rada P, Ladenheim B, Cadet JL, Schwartz GJ, Moran TH, Hoebel BG (2001) Excessive sugar intake alters binding to dopamine and mu-opioid receptors in the brain. Neuroreport 12:3549-3552.
14. Della-Zuana O, Presse F, Ortola C, Duhault J, Nahon JL, Levens N (2002) Acute and chronic administration of melanin-concentrating hormone enhances food intake and body weight in Wistar and Sprague-Dawley rats. Int J Obes Relat Metab Disord 26:1289-1295.
15. DiLeone RJ, Georgescu D, Nestler EJ (2003) Lateral hypothalamic neuropeptides in reward and drug addiction. Life Sci 73:759-768.
16. Doggrell SA (2003) Does the melanin-concentrating hormone antagonist SNAP-7941 deserve 3As? Expert Opin Investig Drugs 12:1035-1038.
17. Egli M (2003) Peptides: their role in excess alcohol drinking and their promise as a therapeutic tool. Physiol Behav 79:89-93.
18. Georgescu D, Sears RM, Hommel JD, Barrot M, Bolanos CA, Marsh DJ, Bednarek MA, Bibb JA, Maratos-Flier E, Nestler EJ, DiLeone RJ (2005) The hypothalamic neuropeptide melanin-concentrating hormone acts in the nucleus accumbens to modulate feeding behavior and forced-swim performance. J Neurosci 25:2933-2940.
19. Grant KA, Samson HH (1985) Oral self administration of ethanol in free feeding rats. Alcohol 2:317-321.
20. Grupp LA, Killian M, Perlanski E, Stewart RB (1988) Angiotensin II reduces voluntary alcohol intake in the rat. Pharmacol Biochem Behav 29:479-482.
21. Grupp LA, Perlanski E, Stewart RB (1989) Systemic angiotensin II acts at the subfornical organ to suppress voluntary alcohol consumption. Pharmacol Biochem Behav 34:201-205.
22. Harwood HJ, Fountain D, Livermore G (1998) Economic costs of alcohol abuse and alcoholism. Recent Dev Alcohol 14:307-330.
23. Heilig M, Soderpalm B, Engel JA, Widerlov E (1989) Centrally administered neuropeptide Y (NPY) produces anxiolytic-like effects in animal anxiety models. Psychopharmacology (Berl) 98:524-529.
24. Heilig M, Widerlov E (1990) Neuropeptide Y: an overview of central distribution, functional aspects, and possible involvement in neuropsychiatric illnesses. Acta Psychiatr Scand 82:95-114.
25. Hoebel BG, Teitelbaum P (1962) Hypothalamic control of feeding and self-stimulation. Science 135:375-377.
26. Ilveskoski E, Kajander OA, Lehtimaki T, Kunnas T, Karhunen PJ, Heinala P, Virkkunen M, Alho H (2001) Association of neuropeptide Y polymorphism with the occurrence of type 1 and type 2 alcoholism. Alcohol Clin Exp Res 25:1420-1422.
27. Kauhanen J, Karvonen MK, Pesonen U, Koulu M, Tuomainen TP, Uusitupa MI, Salonen JT (2000) Neuropeptide Y polymorphism and alcohol consumption in middle-aged men. Am J Med Genet 93:117-121.
28. Kela J, Salmi P, Rimondini-Giorgini R, Heilig M, Wahlestedt C (2003) Behavioural analysis of melanin-concentrating hormone in rats: evidence for orexigenic and anxiolytic properties. Regul Pept 114:109-114.
29. Kim DJ, Yoon SJ, Choi B, Kim TS, Woo YS, Kim W, Myrick H, Peterson BS, Choi YB, Kim YK, Jeong J (2005) Increased fasting plasma ghrelin levels during alcohol abstinence. Alcohol Alcohol 40:76-79.
30. Kinoshita H, Harbuz MS, Nishiguchi M, Ouchi H, Minami T, Utsumi T, Motomura H, Hishida S (2004) High alcohol preferring (HAP) and low alcohol preferring (LAP) rats show altered proopiomelanocortin (POMC) messenger RNA expression in the arcuate nucleus. Alcohol Alcohol 39:406-409.
31. Kratz CM, Levitsky DA, Lustick SL (1978) Long term effects of quinine on food intake and body weight in the rat. Physiol Behav 21:321-324.
32. Kraus T, Reulbach U, Bayerlein K, Mugele B, Hillemacher T, Sperling W, Kornhuber J, Bleich S (2004) Leptin is associated with craving in females with alcoholism. Addict Biol 9:213-219.
33. Kulkosky PJ, Clayborne YJ, Sandoval SL (1993) Cholecystokinin and bombesin inhibit ethanol and food intake in rats selectively bred for ethanol sensitivity. Alcohol Clin Exp Res 17:545-551.
34. Lindblom J, Wikberg JE, Bergstrom L (2002) Alcohol-preferring AA rats show a derangement in their central melanocortin signalling system. Pharmacol Biochem Behav 72:491-496.
35. Ludwig DS, Tritos NA, Mastaitis JW, Kulkarni R, Kokkotou E, Elmquist J, Lowell B, Flier JS, Maratos-Flier E (2001) Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance. J Clin Invest 107:379-386.
36. Margules DL, Olds J (1962) Identical feeding' and 'rewarding' systems in the lateral hypothalamus of rats. Science 135:374-375.
37. Markou A, Kosten TR, Koob GF (1998) Neurobiological similarities in depression and drug dependence: a self-medication hypothesis. Neuropsychopharmacology 18:135-174.
38. Marsh DJ, Weingarth DT, Novi DE, Chen HY, Trumbauer ME, Chen AS, Guan XM, Jiang MM, Feng Y, Camacho RE, Shen Z, Frazier EG, Yu H, Metzger JM, Kuca SJ, Shearman LP, Gopal-Truter S, MacNeil DJ, Strack AM, MacIntyre DE, Van der Ploeg LH, Qian S (2002) Melanin-concentrating hormone 1 receptor-deficient mice are lean, hyperactive, and hyperphagic and have altered metabolism. Proc Natl Acad Sci USA 99:3240-3245.
39. Mayfield RD, Lewohl JM, Dodd PR, Herlihy A, Liu J, Harris RA (2002) Patterns of gene expression are altered in the frontal and motor cortices of human alcoholics. J Neurochem 81:802-813.
40. Merikangas KR, Stevens DE, Fenton B, Stolar M, O'Malley S, Woods SW, Risch N (1998) Co-morbidity and familial aggregation of alcoholism and anxiety disorders. Psychol Med 28:773-788.
41. Mokdad AH, Marks JS, Stroup DF, Gerberding JL (2004) Actual causes of death in the United States, 2000. JAMA 291:1238-1245.
42. Monzon ME, De Barioglio SR (1999) Response to novelty after i.c.v. injection of melanin-concentrating hormone (MCH) in rats. Physiol Behav 67:813-817.
43. Monzon ME, Varas MM, De Barioglio SR (2001) Anxiogenesis induced by nitric oxide synthase inhibition and anxiolytic effect of melanin-concentrating hormone (MCH) in rat brain. Peptides 22(7):1043-1047.
44. Navarro M, Cubero I, Knapp DJ, Thiele TE (2003) MTII-induced reduction of voluntary ethanol drinking is blocked by pretreatment with AgRP-(83-132). Neuropeptides 37:338-344.
45. O'Brien CP, Volpicelli LA, Volpicelli JR (1996) Naltrexone in the treatment of alcoholism: a clinical review. Alcohol 13:35-39.
46. Paxinos G, Watson, C (1998) The Rat Brain in Stereotaxic Coordinates. 4th ed. Academic Press, San Diego.
47. Pissios P, Maratos-Flier E (2003) Melanin-concentrating hormone: from fish skin to skinny mammals. Trends Endocrinol Metab 14:243-248.
48. Presse F, Nahon JL (1993) Differential regulation of melanin- concentrating hormone gene expression in distinct hypothalamic areas under osmotic stimulation in rat. Neuroscience 55:709-720.
49. Rossi M, Choi SJ, O'Shea D, Miyoshi T, Ghatei MA, Bloom SR (1997) Melanin-concentrating hormone acutely stimulates feeding, but chronic administration has no effect on body weight. Endocrinology 138:351-355.
50. Saito Y, Cheng M, Leslie FM, Civelli O (2001) Expression of the melanin-concentrating hormone (MCH) receptor mRNA in the rat brain. J Comp Neurol 435:26-40.
51. Samson HH (1986) Initiation of ethanol reinforcement using a sucrose-substitution procedure in food- and water-sated rats. Alcohol Clin Exp Res 10:436-442.
52. Schwartz MW, Woods SC, Porte D Jr, Seeley RJ, Baskin DG (2000) Central nervous system control of food intake. Nature 404:661-671.
53. Sclafani A, Ackroff K (1994) Glucose- and fructose-conditioned flavor preferences in rats: taste versus postingestive conditioning. Physiol Behav 56:399-405.
54. Shearman LP, Camacho RE, Sloan Stribling D, Zhou D, Bednarek MA, Hreniuk DL, Feighner SD, Tan CP, Howard AD, Van der Ploeg LH, MacIntyre DE, Hickey GJ, Strack AM (2003) Chronic MCH-1 receptor modulation alters appetite, body weight and adiposity in rats. Eur J Pharmacol 475:37-47.
55. Shi Y (2004) Beyond skin color: emerging roles of melanin-concentrating hormone in energy homeostasis and other physiological functions. Peptides 25:1605-1611.
56. Shimada M, Tritos NA, Lowell BB, Flier JS, Maratos-Flier E (1998) Mice lacking melanin-concentrating hormone are hypophagic and lean. Nature 396:670-674.
57. Spangler R, Wittkowski KM, Goddard NL, Avena NM, Hoebel BG, Leibowitz SF (2004) Opiate-like effects of sugar on gene expression in reward areas of the rat brain. Brain Res Mol Brain Res 124:134-142.
58. Suply T, Della Zuana O, Audinot V, Rodriguez M, Beauverger P, Duhault J, Canet E, Galizzi JP, Nahon JL, Levens N, Boutin JA (2001) SLC-1 receptor mediates effect of melanin-concentrating hormone on feeding behavior in rat: a structure-activity study. J Pharmacol Exp Ther 299:137-146.
59. Suzuki R, Lumeng L, McBride WJ, Li TK, Hwang BH (2004) Reduced neuropeptide Y mRNA expression in the central nucleus of amygdala of alcohol preferring (P) rats: its potential involvement in alcohol preference and anxiety. Brain Res 1014:251-254.
60. Swendsen JD, Merikangas KR (2000) The comorbidity of depression and substance use disorders. Clin Psychol Rev 20:173-189.
61. Swendsen JD, Merikangas KR, Canino GJ, Kessler RC, Rubio-Stipec M, Angst J (1998) The comorbidity of alcoholism with anxiety and depressive disorders in four geographic communities. Compr Psychiatry 39:176-184.
62. Swift RM (1995) Effect of naltrexone on human alcohol consumption. J Clin Psychiatry 56;Suppl 7:24-29.
63. Thiele TE, Marsh DJ, Ste Marie L, Bernstein IL, Palmiter RD (1998) Ethanol consumption and resistance are inversely related to neuropeptide Y levels. Nature 396:366-369.
64. Thiele TE, Navarro M, Sparta DR, Fee JR, Knapp DJ, Cubero I (2003) Alcoholism and obesity: overlapping neuropeptide pathways? Neuropeptides 37:321-337.
65. Thiele TE, Sparta DR, Hayes DM, Fee JR (2004) A role for neuropeptide Y in neurobiological responses to ethanol and drugs of abuse. Neuropeptides 38:235-243.
66. Thomas SE, Randall CL, Carrigan MH (2003) Drinking to cope in socially anxious individuals: a controlled study. Alcohol Clin Exp Res 27:1937-1943.
67. Tolliver GA, Sadeghi KG, Samson HH (1988) Ethanol preference following the sucrose-fading initiation procedure. Alcohol 5:9-13.
68. Valenstein ES, Cox VC, Kakolewski JW (1968) Modification of motivated behavior elicited by electrical stimulation of the hypothalamus. Science 159:1119-1121.
69. Woods SC, Seeley RJ, Porte D Jr, Schwartz MW (1998) Signals that regulate food intake and energy homeostasis. Science 280:1378-1383.
70. Woodworth CH (1971) Attack elicited in rats by electrical stimulation of the lateral hypothalamus. Physiol Behav 6:345-353.