Determination of drug-like properties of a novel antileishmanial compound: In vitro absorption, distribution, metabolism, and excretion studies

Indian Journal of Pharmacology

Volumn 41, Issue 4, 2009, Pages 176-181

  Mondal, Susanta Kumar ^a   Mondal, Nirup B ^b   Banerjee, Sukdeb ^b   Mazumder, Upal Kanti ^a  

^a JADAVPUR UNIVERSITY   (India)

^b INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

Author keywords

Absorption; Antileishmanial compound; Distribution; Metabolism and excretion; Parallel artificial membrane permeability assay; Rat liver microsome; Solubility; Stability

Indexed keywords

2 (2 METHYLQUINOLIN 4 YLAMINO) N PHENYLACETAMIDE; ACETANILIDE DERIVATIVE; ANTILEISHMANIAL AGENT; ATENOLOL; CAFFEINE; CHLORAMPHENICOL; CYCLOHEXANE; DICLOFENAC; DIETHYLSTILBESTROL; FUROSEMIDE; HALOPERIDOL; IMIPRAMINE; KETOCONAZOLE; METHOTREXATE; METOPROLOL TARTRATE; OCTANOL; PHOSPHATE BUFFERED SALINE; PROPRANOLOL DERIVATIVE; QUINOLINE DERIVATIVE; RANITIDINE; TAMOXIFEN; UNCLASSIFIED DRUG; VERAPAMIL; WARFARIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG ADMINISTRATION ROUTE; DRUG DISTRIBUTION; DRUG METABOLISM; DRUG PENETRATION; DRUG PROTEIN BINDING; DRUG STRUCTURE; EQUILIBRIUM DIALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LEISHMANIA DONOVANI; LEISHMANIASIS; LIVER MICROSOME METABOLISM; NONHUMAN; RAT; SPECTROPHOTOMETRY; VALIDATION PROCESS;

EID: 70349833199     PISSN: 02537613     EISSN: 19983751     Source Type: Journal    
DOI: 10.4103/0253-7613.56075     Document Type: Article

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