Application of parallel liquid chromatography/mass spectrometry for high throughput microsomal stability screening of compound libraries

Journal of the American Society for Mass Spectrometry

Volumn 13, Issue 2, 2002, Pages 155-165

  Xu, Rongda ^a   Nemes, Csaba ^a   Jenkins, Kelly M ^a   Rourick, Robyn A ^a   Kassel, Daniel B ^a   Liu, Charles Z C ^b  

^a DUPONT COMPANY   (United States)

^b APPLIED BIOSYSTEMS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASSAYS; DRUG THERAPY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; SAMPLING; SOLUTIONS;

MICROSOSMAL STABILITY SCREENING;

LIBRARIES;

DRUG;

LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY;

ARTICLE; CONTROLLED STUDY; DRUG SCREENING; INFORMATION PROCESSING; INJECTION; INTEGRATION; LIBRARY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETER; MASS SPECTROMETRY; MICROSOME; NONHUMAN; SAMPLE; SCREENING; TECHNIQUE;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DATA DISPLAY; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; INDICATORS AND REAGENTS; MICROSOMES; PEPTIDE LIBRARY; PHARMACEUTICAL PREPARATIONS; REFERENCE STANDARDS; SOFTWARE;

EID: 0036112196     PISSN: 10440305     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1044-0305(01)00342-7     Document Type: Article

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