Combination therapy with indolylquinoline derivative and sodium antimony gluconate cures established visceral Leishmaniasis in hamsters

Antimicrobial Agents and Chemotherapy

Volumn 46, Issue 1, 2002, Pages 259-261

  Pal, C ^a   Raha, M ^a   Basu, A ^a   Chandra Roy, K ^a   Gupta, A ^a   Ghosh, M ^a   Prasad Sahu, N ^a   Banerjee, S ^a   Bikash Mandal, N ^a   Bandyopadhyay, S ^a  

^a INDIAN INSTITUTE OF CHEMICAL BIOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2'' DICHLOROACETAMIDOBENZYL) 3 (3' INDOLYLQUINOLINE); ANTIMONY GLUCONATE; INDOLE DERIVATIVE; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; HAMSTER; HEPATITIS; LEISHMANIA DONOVANI; MALE; NONHUMAN; PARASITEMIA; PRIORITY JOURNAL; SPLEEN DISEASE; TREATMENT OUTCOME; VISCERAL LEISHMANIASIS;

ANIMALS; ANTIMONY SODIUM GLUCONATE; ANTIPROTOZOAL AGENTS; CRICETINAE; DISEASE MODELS, ANIMAL; DRUG THERAPY, COMBINATION; INDOLES; LEISHMANIASIS, VISCERAL; QUINOLINES; TREATMENT OUTCOME;

EID: 0036135454     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.46.1.259-261.2002     Document Type: Article

References (14)

1. Immunotherapy for Leishmania donovani infection in golden hamsters: Combinatorial action of poly ICLC plus L-arginine and sodium stibogluconate (stibanate)
2. Indolylquinoline derivatives are cytotoxic to Leishmania donovani promastigotes and amastigotes in vitro and are effective in treating murine visceral leishmaniasis
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5. Synthesis of indolylquinolines under Friedel-Craft reaction condition
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10. Treatment of antimony-unresponsive Indian leishmaniasis with ultra-short courses of amphotericin-B-lipid complex
11. Oral treatment of visceral leishmaniasis with miltefosine
12. Short-course, cost-effective treatment with amphotericin B-fat emulsion cures visceral leishmaniasis
13. Cure of antimony-unresponsive Indian visceral leishmaniasis with amphotericin B lipid complex