An increased throughput method for the determination of partition coefficients

Pharmaceutical Research

Volumn 17, Issue 11, 2000, Pages 1389-1395

  Hitzel, L ^a   Watt, A P ^a   Locker, K L ^a  

^a NEUROSCIENCE RESEARCH CENTRE   (United Kingdom)

Author keywords

High throughput; Log D; Log P; Partition coefficient; Physicochemical

Indexed keywords

2 NAPHTHOIC ACID; 3 NITROANILINE; 4 CHLOROANILINE; 4 NITROPHENOL; ALPRAZOLAM; ALPRENOLOL; AMITRIPTYLINE; ANILINE DERIVATIVE; BENZIMIDAZOLE; BROMAZEPAM; BUFFER; CAFFEINE; CHLORPROMAZINE; CLOFIBRIC ACID; DIAZEPAM; EPHEDRINE; FLUOXETINE; HYDROQUINONE; IBUPROFEN; LIDOCAINE; NAPHTHALENE; NORTRIPTYLINE; OCTANOL; PARACETAMOL; PHENACETIN; PHENOBARBITAL; PHENOLPHTHALEIN; PROCAINE; QUINIDINE; QUININE; SULFAPHENAZOLE; TESTOSTERONE; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; MATERIALS HANDLING; PARTITION COEFFICIENT; PHASE SEPARATION; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ROBOTICS;

1-OCTANOL; BUFFERS; CHEMISTRY, PHYSICAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; PHARMACEUTICAL PREPARATIONS; REPRODUCIBILITY OF RESULTS; SOLUBILITY; WATER;

EID: 0034493887     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1007546905874     Document Type: Article

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