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Volumn 20, Issue 17, 2009, Pages 3783-3791

The class II phosphatidylinositol 3 kinase C2β is required for the activation of the K+ channel KCa3.1 and CD4 T-cells

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ACTIVATED POTASSIUM CHANNEL; NUCLEOSIDE DIPHOSPHATE KINASE; NUCLEOSIDE DIPHOSPHATE KINASE BETA; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE C2 BETA; PHOSPHATIDYLINOSITOL 3 PHOSPHATE; SMALL INTERFERING RNA; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

EID: 70349484446     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E09-05-0390     Document Type: Article
Times cited : (63)

References (51)
  • 1
    • 0036791759 scopus 로고    scopus 로고
    • Two distinct phosphoinositide 3-kinases mediate polypeptide growth factor-stimulated PKB activation
    • Arcaro, A., Khanzada, U. K., Vanhaesebroeck, B., Tetley, T. D., Waterfield, M. D., and Seckl, M. J. (2002). Two distinct phosphoinositide 3-kinases mediate polypeptide growth factor-stimulated PKB activation. EMBO J. 21, 5097-5108.
    • (2002) EMBO J , vol.21 , pp. 5097-5108
    • Arcaro, A.1    Khanzada, U.K.2    Vanhaesebroeck, B.3    Tetley, T.D.4    Waterfield, M.D.5    Seckl, M.J.6
  • 2
    • 0034024403 scopus 로고    scopus 로고
    • Class II phosphoinositide 3-kinases are downstream targets of activated polypeptide growth factor receptors
    • Arcaro, A., Zvelebil, M. J., Wallasch, C., Ullrich, A., Waterfield, M. D., and Domin, J. (2000). Class II phosphoinositide 3-kinases are downstream targets of activated polypeptide growth factor receptors. Mol. Cell. Biol. 20, 3817-3830.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 3817-3830
    • Arcaro, A.1    Zvelebil, M.J.2    Wallasch, C.3    Ullrich, A.4    Waterfield, M.D.5    Domin, J.6
  • 3
    • 33751232672 scopus 로고    scopus 로고
    • Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases
    • Beeton, C., et al. (2006). Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases. Proc. Natl. Acad. Sci. USA 103, 17414-17419.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 17414-17419
    • Beeton, C.1
  • 4
    • 0034866612 scopus 로고    scopus 로고
    • Growth factor regulation of the novel class II phosphoinositide 3-kinases
    • Brown, R. A., and Shepherd, P. R. (2001). Growth factor regulation of the novel class II phosphoinositide 3-kinases. Biochem. Soc. Trans. 29, 535-537.
    • (2001) Biochem. Soc. Trans. , vol.29 , pp. 535-537
    • Brown, R.A.1    Shepherd, P.R.2
  • 5
    • 33746025600 scopus 로고    scopus 로고
    • Bacterial Superantigens Bypass Lck-Dependent T Cell Receptor Signaling by Activating a Gα11-Dependent, PLC-β-Mediated Pathway
    • DOI 10.1016/j.immuni.2006.04.012, PII S1074761306002998
    • Bueno, C., Lemke, C. D., Criado, G., Baroja, M. L., Ferguson, S. S., Rahman, A. K., Tsoukas, C. D., McCormick, J. K., and Madrenas, J. (2006). Bacterial superantigens bypass Lck-dependent T cell receptor signaling by activating a Galpha11-dependent, PLC-beta-mediated pathway. Immunity 25, 67-78. (Pubitemid 44066827)
    • (2006) Immunity , vol.25 , Issue.1 , pp. 67-78
    • Bueno, C.1    Lemke, C.D.2    Criado, G.3    Baroja, M.L.4    Ferguson, S.S.G.5    Rahman, A.K.M.N.-U.6    Tsoukas, C.D.7    McCormick, J.K.8    Madrenas, J.9
  • 6
    • 0034944952 scopus 로고    scopus 로고
    • Molecular properties and physiological roles of ion channels in the immune system
    • Cahalan, M. D., Wulff, H., and Chandy, K. G. (2001). Molecular properties and physiological roles of ion channels in the immune system. J. Clin. Immunol. 21, 235-252.
    • (2001) J. Clin. Immunol. , vol.21 , pp. 235-252
    • Cahalan, M.D.1    Wulff, H.2    Chandy, K.G.3
  • 8
    • 27544441784 scopus 로고    scopus 로고
    • Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling
    • Campi, G., Varma, R., and Dustin, M. L. (2005). Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling. J. Exp. Med. 202, 1031-1036.
    • (2005) J. Exp. Med. , vol.202 , pp. 1031-1036
    • Campi, G.1    Varma, R.2    Dustin, M.L.3
  • 9
    • 0037205048 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase pathway
    • Cantley, L. C. (2002). The phosphoinositide 3-kinase pathway. Science 296, 1655-1657.
    • (2002) Science , vol.296 , pp. 1655-1657
    • Cantley, L.C.1
  • 10
    • 51349131307 scopus 로고    scopus 로고
    • The balance between T cell receptor signaling and degradation at the center of the immunological synapse is determined by antigen quality
    • Cemerski, S., Das, J., Giurisato, E., Markiewicz, M. A., Allen, P. M., Chakraborty, A. K., and Shaw, A. S. (2008). The balance between T cell receptor signaling and degradation at the center of the immunological synapse is determined by antigen quality. Immunity 29, 414-422.
    • (2008) Immunity , vol.29 , pp. 414-422
    • Cemerski, S.1    Das, J.2    Giurisato, E.3    Markiewicz, M.A.4    Allen, P.M.5    Chakraborty, A.K.6    Shaw, A.S.7
  • 11
    • 0036234543 scopus 로고    scopus 로고
    • NFAT signaling: Choreographing the social lives of cells
    • Crabtree, G. R., and Olson, E. N. (2002). NFAT signaling: choreographing the social lives of cells. Cell 109(Suppl), S67-S79.
    • (2002) Cell , vol.109 , Issue.SUPPL.
    • Crabtree, G.R.1    Olson, E.N.2
  • 12
    • 33749011694 scopus 로고    scopus 로고
    • Impact of the immunological synapse on T cell signaling
    • Dustin, M. L. (2006). Impact of the immunological synapse on T cell signaling. Results Probl. Cell Differ. 43, 175-198.
    • (2006) Results Probl. Cell Differ , vol.43 , pp. 175-198
    • Dustin, M.L.1
  • 13
    • 0034232037 scopus 로고    scopus 로고
    • The immunological synapse and the actin cytoskeleton: Molecular hardware for T cell signaling
    • Dustin, M. L., and Cooper, J. A. (2000). The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling. Nat. Immunol. 1, 23-29.
    • (2000) Nat. Immunol. , vol.1 , pp. 23-29
    • Dustin, M.L.1    Cooper, J.A.2
  • 15
    • 0035853712 scopus 로고    scopus 로고
    • Calcium-activated potassium channels sustain calcium signaling in T lymphocytes. Selective blockers and manipulated channel expression levels
    • Fanger, C. M., Rauer, H., Neben, A. L., Miller, M. J., Wulff, H., Rosa, J. C., Ganellin, C. R., Chandy, K. G., and Cahalan, M. D. (2001). Calcium-activated potassium channels sustain calcium signaling in T lymphocytes. Selective blockers and manipulated channel expression levels. J. Biol. Chem. 276, 12249-12256.
    • (2001) J. Biol. Chem. , vol.276 , pp. 12249-12256
    • Fanger, C.M.1    Rauer, H.2    Neben, A.L.3    Miller, M.J.4    Wulff, H.5    Rosa, J.C.6    Ganellin, C.R.7    Chandy, K.G.8    Cahalan, M.D.9
  • 16
    • 34548233165 scopus 로고    scopus 로고
    • Calcium signalling in lymphocyte activation and disease
    • Feske, S. (2007). Calcium signalling in lymphocyte activation and disease. Nat. Rev. Immunol. 7, 690-702.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 690-702
    • Feske, S.1
  • 17
  • 20
    • 34247098841 scopus 로고    scopus 로고
    • The role of class I phosphoinositide 3-kinase in T-cell function and autoimmunity
    • Fruman, D. A. (2007). The role of class I phosphoinositide 3-kinase in T-cell function and autoimmunity. Biochem. Soc. Trans. 35, 177-180.
    • (2007) Biochem. Soc. Trans. , vol.35 , pp. 177-180
    • Fruman, D.A.1
  • 21
    • 0035103107 scopus 로고    scopus 로고
    • The class II phosphoinositide 3-kinase C2α is activated by clathrin and regulates clathrin-mediated membrane trafficking
    • DOI 10.1016/S1097-2765(01)00191-5
    • Gaidarov, I., Smith, M. E., Domin, J., and Keen, J. H. (2001). The class II phosphoinositide 3-kinase C2alpha is activated by clathrin and regulates clathrin-mediated membrane trafficking. Mol. Cell 7, 443-449. (Pubitemid 32206511)
    • (2001) Molecular Cell , vol.7 , Issue.2 , pp. 443-449
    • Gaidarov, I.1    Smith, M.E.K.2    Domin, J.3    Keen, J.H.4
  • 22
    • 0034711234 scopus 로고    scopus 로고
    • Up-regulation of the IKCa1 potassium channel during T-cell activation. Molecular mechanism and functional consequences
    • Ghanshani, S., Wulff, H., Miller, M. J., Rohm, H., Neben, A., Gutman, G. A., Cahalan, M. D., and Chandy, K. G. (2000). Up-regulation of the IKCa1 potassium channel during T-cell activation. Molecular mechanism and functional consequences. J. Biol. Chem. 275, 37137-37149.
    • (2000) J. Biol. Chem. , vol.275 , pp. 37137-37149
    • Ghanshani, S.1    Wulff, H.2    Miller, M.J.3    Rohm, H.4    Neben, A.5    Gutman, G.A.6    Cahalan, M.D.7    Chandy, K.G.8
  • 23
    • 0035871081 scopus 로고    scopus 로고
    • Cellular functions of phosphatidylinositol 3-phosphate and FYVE domain proteins
    • DOI 10.1042/0264-6021:3550249
    • Gillooly, D. J., Simonsen, A., and Stenmark, H. (2001). Cellular functions of phosphatidylinositol 3-phosphate and FYVE domain proteins. Biochem. J. 355, 249-258. (Pubitemid 32397782)
    • (2001) Biochemical Journal , vol.355 , Issue.2 , pp. 249-258
    • Gillooly, D.J.1    Simonsen, A.2    Stenmark, H.3
  • 24
    • 0033538574 scopus 로고    scopus 로고
    • The immunological synapse: A molecular machine controlling T cell activation
    • DOI 10.1126/science.285.5425.221
    • Grakoui, A., Bromley, S. K., Sumen, C., Davis, M. M., Shaw, A. S., Allen, P. M., and Dustin, M. L. (1999a). The immunological synapse: a molecular machine controlling T cell activation. Science 285, 221-227. (Pubitemid 29329988)
    • (1999) Science , vol.285 , Issue.5425 , pp. 221-227
    • Grakoui, A.1    Bromley, S.K.2    Sumen, C.3    Davis, M.M.4    Shaw, A.S.5    Allen, P.M.6    Dustin, M.L.7
  • 25
    • 0033538574 scopus 로고    scopus 로고
    • The immunological synapse: A molecular machine controlling T cell activation
    • DOI 10.1126/science.285.5425.221
    • Grakoui, A., Bromley, S. K., Sumen, C., Davis, M. M., Shaw, A. S., Allen, P. M., and Dustin, M. L. (1999b). The immunological synapse: a molecular machine controlling T cell activation. Science 285, 221-227. (Pubitemid 29329988)
    • (1999) Science , vol.285 , Issue.5425 , pp. 221-227
    • Grakoui, A.1    Bromley, S.K.2    Sumen, C.3    Davis, M.M.4    Shaw, A.S.5    Allen, P.M.6    Dustin, M.L.7
  • 26
    • 0033570334 scopus 로고    scopus 로고
    • Domains responsible for constitutive and Ca(2+)-dependent interactions between calmodulin and small conductance Ca(2+)-activated potassium channels
    • Keen, J. E., Khawaled, R., Farrens, D. L., Neelands, T., Rivard, A., Bond, C. T., Janowsky, A., Fakler, B., Adelman, J. P., and Maylie, J. (1999). Domains responsible for constitutive and Ca(2+)-dependent interactions between calmodulin and small conductance Ca(2+)-activated potassium channels. J. Neurosci. 19, 8830-8838.
    • (1999) J. Neurosci. , vol.19 , pp. 8830-8838
    • Keen, J.E.1    Khawaled, R.2    Farrens, D.L.3    Neelands, T.4    Rivard, A.5    Bond, C.T.6    Janowsky, A.7    Fakler, B.8    Adelman, J.P.9    Maylie, J.10
  • 27
    • 34247163550 scopus 로고    scopus 로고
    • Chemically targeting the PI3K family
    • Knight, Z. A., and Shokat, K. M. (2007). Chemically targeting the PI3K family. Biochem. Soc. Trans. 35, 245-249.
    • (2007) Biochem. Soc. Trans. , vol.35 , pp. 245-249
    • Knight, Z.A.1    Shokat, K.M.2
  • 28
    • 0034714184 scopus 로고    scopus 로고
    • Differential clustering of CD4 and CD3ζ during T cell recognition
    • DOI 10.1126/science.289.5483.1349
    • Krummel, M. F., Sjaastad, M. D., Wulfing, C., and Davis, M. M. (2000). Differential clustering of CD4 and CD3zeta during T cell recognition. Science 289, 1349-1352. (Pubitemid 30656051)
    • (2000) Science , vol.289 , Issue.5483 , pp. 1349-1352
    • Krummel, M.F.1    Sjaastad, M.D.2    Wulfing, C.W.3    Davis, M.M.4
  • 29
    • 22344452002 scopus 로고    scopus 로고
    • Class II phosphoinositide 3-kinase defines a novel signaling pathway in cell migration
    • DOI 10.1083/jcb.200408005
    • Maffucci, T., Cooke, F. T., Foster, F. M., Traer, C. J., Fry, M. J., and Falasca, M. (2005). Class II phosphoinositide 3-kinase defines a novel signaling pathway in cell migration. J. Cell Biol. 169, 789-799. (Pubitemid 41002884)
    • (2005) Journal of Cell Biology , vol.169 , Issue.5 , pp. 789-799
    • Maffucci, T.1    Cooke, F.T.2    Foster, F.M.3    Traer, C.J.4    Fry, M.J.5    Falasca, M.6
  • 31
    • 0032480279 scopus 로고    scopus 로고
    • Three-dimensional segregation of supramolecular activation clusters in T cells
    • DOI 10.1038/25764
    • Monks, C. R., Freiberg, B. A., Kupfer, H., Sciaky, N., and Kupfer, A. (1998). Three-dimensional segregation of supramolecular activation clusters in T cells. Nature 395, 82-86. (Pubitemid 28420234)
    • (1998) Nature , vol.395 , Issue.6697 , pp. 82-86
    • Monks, C.R.F.1    Freiberg, B.A.2    Kupfer, H.3    Sciaky, N.4    Kupfer, A.5
  • 32
    • 34247337971 scopus 로고    scopus 로고
    • The Ca(2+)-activated K(+) channel KCa3.1 compartmentalizes in the immunological synapse of human T lymphocytes
    • Nicolaou, S. A., Neumeier, L., Peng, Y., Devor, D. C., and Conforti, L. (2007). The Ca(2+)-activated K(+) channel KCa3.1 compartmentalizes in the immunological synapse of human T lymphocytes. Am J. Physiol. Cell Physiol. 292, C1431-C1439.
    • (2007) Am J. Physiol. Cell Physiol , vol.292
    • Nicolaou, S.A.1    Neumeier, L.2    Peng, Y.3    Devor, D.C.4    Conforti, L.5
  • 34
    • 34247155266 scopus 로고    scopus 로고
    • The PI3K p110delta controls T-cell development, differentiation and regulation
    • Patton, D. T., Garcon, F., and Okkenhaug, K. (2007). The PI3K p110delta controls T-cell development, differentiation and regulation. Biochem. Soc. Trans. 35, 167-171.
    • (2007) Biochem. Soc. Trans. , vol.35 , pp. 167-171
    • Patton, D.T.1    Garcon, F.2    Okkenhaug, K.3
  • 37
    • 38949155889 scopus 로고    scopus 로고
    • Signal initiation in T-cell receptor microclusters
    • Seminario, M. C., and Bunnell, S. C. (2008). Signal initiation in T-cell receptor microclusters. Immunol. Rev. 221, 90-106.
    • (2008) Immunol. Rev. , vol.221 , pp. 90-106
    • Seminario, M.C.1    Bunnell, S.C.2
  • 42
    • 33644765808 scopus 로고    scopus 로고
    • Essential role of PI3Kδ and PI3Kγ in thymocyte survival
    • DOI 10.1182/blood-2005-08-3300
    • Swat, W., Montgrain, V., Doggett, T. A., Douangpanya, J., Puri, K., Vermi, W., and Diacovo, T. G. (2006). Essential role of PI3Kdelta and PI3Kgamma in thymocyte survival. Blood 107, 2415-2422. (Pubitemid 43345562)
    • (2006) Blood , vol.107 , Issue.6 , pp. 2415-2422
    • Swat, W.1    Montgrain, V.2    Doggett, T.A.3    Douangpanya, J.4    Puri, K.5    Vermi, W.6    Diacovo, T.G.7
  • 43
    • 33745310789 scopus 로고    scopus 로고
    • Are class II phosphoinositide 3-kinases potential targets for anticancer therapies?
    • Traer, C. J., Foster, F. M., Abraham, S. M., and Fry, M. J. (2006). Are class II phosphoinositide 3-kinases potential targets for anticancer therapies? Bull. Cancer 93, E53-58.
    • (2006) Bull. Cancer , vol.93
    • Traer, C.J.1    Foster, F.M.2    Abraham, S.M.3    Fry, M.J.4
  • 44
    • 33746011209 scopus 로고    scopus 로고
    • T Cell Receptor-Proximal Signals Are Sustained in Peripheral Microclusters and Terminated in the Central Supramolecular Activation Cluster
    • DOI 10.1016/j.immuni.2006.04.010, PII S1074761306002974
    • Varma, R., Campi, G., Yokosuka, T., Saito, T., and Dustin, M. L. (2006). T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster. Immunity 25, 117-127. (Pubitemid 44066825)
    • (2006) Immunity , vol.25 , Issue.1 , pp. 117-127
    • Varma, R.1    Campi, G.2    Yokosuka, T.3    Saito, T.4    Dustin, M.L.5
  • 45
    • 23844462453 scopus 로고    scopus 로고
    • Cutting edge: T cell development requires the combined activities of the p110γ and p110δ catalytic isoforms of phosphatidylinositol 3-kinase
    • Webb, L. M., Vigorito, E., Wymann, M. P., Hirsch, E., and Turner, M. (2005). Cutting edge: T cell development requires the combined activities of the p110gamma and p110delta catalytic isoforms of phosphatidylinositol 3-kinase. J. Immunol. 175, 2783-2787. (Pubitemid 41170493)
    • (2005) Journal of Immunology , vol.175 , Issue.5 , pp. 2783-2787
    • Webb, L.M.C.1    Vigorito, E.2    Wymann, M.P.3    Hirsch, E.4    Turner, M.5
  • 46
    • 0142059887 scopus 로고    scopus 로고
    • Potassium channels as therapeutic targets for autoimmune disorders
    • Wulff, H., Beeton, C., and Chandy, K. G. (2003a). Potassium channels as therapeutic targets for autoimmune disorders. Curr. Opin. Drug Discov. Dev. 6, 640-647.
    • (2003) Curr. Opin. Drug Discov. Dev. , vol.6 , pp. 640-647
    • Wulff, H.1    Beeton, C.2    Chandy, K.G.3
  • 49
    • 34247133465 scopus 로고    scopus 로고
    • Regulation of class III (Vps34) PI3Ks
    • Yan, Y., and Backer, J. M. (2007). Regulation of class III (Vps34) PI3Ks. Biochem. Soc. Trans. 35, 239-241.
    • (2007) Biochem. Soc. Trans. , vol.35 , pp. 239-241
    • Yan, Y.1    Backer, J.M.2
  • 50


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