Mechanism of calcium gating in small-conductance calcium-activated potassium channels

Nature

Volumn 395, Issue 6701, 1998, Pages 503-507

  Xia, X M ^a   Fakler, B ^b   Rivard, A ^a   Wayman, G ^a   Johnson Pais, T ^a   Keen, J E ^a   Ishii, T ^a   Hirschberg, B ^a   Bond, C T ^a   Lutsenko, S ^a   Maylie, J ^a   Adelman, J P ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CALMODULIN; POTASSIUM CHANNEL;

ARTICLE; CHANNEL GATING; MEMBRANE BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; YEAST;

ANIMALS; BINDING SITES; CALCIUM; CALMODULIN; ELECTROPHYSIOLOGY; GLUTATHIONE TRANSFERASE; ION CHANNEL GATING; MUTAGENESIS, SITE-DIRECTED; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; RATS; RECOMBINANT PROTEINS; SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; XENOPUS;

EID: 0032189766     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/26758     Document Type: Article

References (30)

1. Hille, B. Ionic Channels of Excitable Membranes (Sinauer, Sunderland, 1992).
2. Lancaster, B., Nicoll, R. A. & Perkel, D. J. Calcium activates two types of potassium channels in rat hippocampal neurons in culture. J. Neurosci. 11, 23-30 (1991).
3. Sah, P. Properties of channels mediating the apamin-insensitive afterhyperpolarization in vagal motoneurons. J. Neurophysiol. 74, 1772-1776 (1995).
4. Schatzmann, H. J. in Membrane Transport of Calcium (ed. Carafoli, E.) 41-108 (Academic, London, 1982).
5. Clapham, D. E. Calcium signaling. Cell 80, 259-268 (1995).
6. Köhler, M. et al. Small-conductance, calcium-activated potassium channels from mammalian brain. Science 273, 1709-1714 (1996).
7. Lester, R. A., Clements, J. D., Westbrook, G. L. & Jahr, C. E. Channel kinetics determine the time course of NMDA receptor-mediated synaptic currents. Nature 346, 565-567 (1990).
8. A receptors open? Neuron 12, 61-71 (1994).
9. Persechini, A., Moncrief, N. D. & Kretsinger, R. H. The EF-hand family of calcium-modulated proteins. Trends Neurosci. 12, 462-467 (1989).
10. 2 domains of synaptotagmin and protein kinase C. Science 273, 248-251 (1996).
11. Schreiber, M. & Salkoff, L. A novel calcium-sensing domain in the BK channel. Biophys. J. 73, 1355-1363 (1997).
12. Miyano, O., Kameshita, I. & Fugisawa, H. Purification and characterization of a brain-specific multifunctional calmodulin-dependent protein kinase from rat cerebellum. J. Biol. chem. 267, 1198-1203 (1992).
13. Fischer, T. H., Campbell, K. P. & White, G. C An investigation of functional similarities between the sarcoplasmic reticulum and platelet calcium-dependent adenositetriphosphatases with the inhibitors quercetin and calmidazolium. Biochemistry 26, 8024-8030 (1987).
14. 2+ calmodulin-dependent protein kinase II. J. Biol. Chem. 263, 18145-18151 (1988).
15. Picton, C., Klee, C. B. & Cohen, P. Phosphorylase kinase from rabbit skeletal muscle: identification of the calmodulin-binding subunits. J. Biol. Chem. 111, 553-561 (1980).
16. Geiser, J. R., Tuinen, D. V., Brockerhoff, S. E., Neff, M. M. & Davis, T. N. Can calmodulin function without binding calcium? Cell 65, 949-959 (1991).
17. Putkey, J. A., Sweeney, H. L. & Campbell, S. T. Site-directed mutation of the trigger calcium-binding site in cardiac troponin C. J. Biol. Chem. 264, 12370-12378 (1989).
18. Chien, Y. & Dawid, I. B. Isolation and characterization of calmodulin genes from Xenopus laevis. Mol. Cell. Biol. 4, 507-513 (1984).
19. Langosch, D., Thomas, L. & Betz, H. Conserved quaternary structure of ligand-gated ion channels: the postsynaptic glycine receptor is a pentamer. Proc. Natl Acad. Sci. USA 85, 7394-7398 (1988).
20. A receptors depend upon subunit composition. Neuron 4, 919-928 (1990).
21. Monyer, H. et al. Heteromeric NMDA receptors: molecular and functional distinction of subtypes. Science 256, 1217-1221 (1992).
22. Herb, A. et al. The KA-2 subunit of excitatory amino acid receptors shows widespread expression in brain and forms ion channels with distantly related subunits. Neuron 8, 775-785 (1992).
23. Galzi, J.-L., Revah, F., Bessis, A. & Changeux, J.-P. Functional architecture of the nicotinic acetylcholine receptor: from electric organ to brain. Annu. Rev. Pharmacol. 31, 37-72 (1991).
24. Adelman, J. P. Proteins that interact with the pore-forming subunits of voltage-gated ion channels. Curr. Opin. Neurobiol. 5, 286-295 (1995).
25. Wylie, D. C. & Vanaman, T. C. in Calmodulin (eds Cohen, P. & Klee, C. B.) 1-15 (Elsevier, Amsterdam, 1988).
26. + current missing in a mutant of Paramecium. Science 232, 503-506 (1986).
27. Weiner, M. P. et al. Site-directed mutagenesis of double-stranded DNA by the polymerase chain reaction. Gene 151, 119-123 (1994).
28. Fabiato, A. & Fabiato, F. Calculator programs for computing the composition of the solutions containing multiple metals and ligands for experiments in skinned muscle cells. J. Physiol. 75, 463-505 (1979).
29. + channels. Biophys. J. 74, 2318-2326 (1998).
30. Chevray, P. M. & Nathans, D. Protein interaction cloning in yeast: identification of mammalian proteins that reacted with the leucine zipper of Jun. Proc. Natl Acad. Sci. USA 89, 5789-5793 (1992).