Reduced ATR or Chk1 expression leads to chromosome instability and chemosensitization of mismatch repair-deficient colorectal cancer cells

Molecular Biology of the Cell

Volumn 20, Issue 17, 2009, Pages 3801-3809

  Jardim, Melanie J ^a   Wang, Qinhong ^a   Furumai, Ryohei ^a   Wakeman, Timothy ^a   Goodman, Barbara K ^a   Wang, Xiao Fan ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APC PROTEIN; ATR PROTEIN; CHECKPOINT KINASE 1; FLUOROURACIL; SMALL INTERFERING RNA;

ARTICLE; CANCER CELL; CARCINOGENESIS; CENTROMERE; CHEMOSENSITIZATION; CHROMOSOMAL INSTABILITY; COLORECTAL CANCER; DNA DAMAGE; DOUBLE STRANDED DNA BREAK; HUMAN; HUMAN CELL; MICRONUCLEUS; MICROSATELLITE INSTABILITY; MISMATCH REPAIR; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CENTROSOME; CHROMOSOMAL INSTABILITY; COLORECTAL NEOPLASMS; DNA BREAKS, DOUBLE-STRANDED; DNA MISMATCH REPAIR; FLUOROURACIL; HUMANS; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; RNA, SMALL INTERFERING;

EID: 70349349038     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E09-04-0303     Document Type: Article

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