Biophysical defects in voltage-gated sodium channels associated with long QT and Brugada syndromes

Channels

Volumn 2, Issue 2, 2008, Pages 70-80

  Jones, David K ^a   Ruben, Peter C ^a  

^a SIMON FRASER UNIVERSITY   (Canada)

Author keywords

Activation; Arrhythmia; BrS; Electrocardiogram; Endocardium; Epicardium; Inactivation; LQT; M cell; Persistent current; Torsade de Pointes; Window current

Indexed keywords

BATRACHOTOXIN; CISAPRIDE; POTASSIUM CHANNEL HERG; QUINIDINE; SODIUM CHANNEL; SOTALOL; VERATRIDINE; VOLTAGE GATED SODIUM CHANNEL;

ACTION POTENTIAL; ATRIOVENTRICULAR BLOCK; BRUGADA SYNDROME; CHANNEL GATING; ECG ABNORMALITY; GENE MUTATION; HEART ARRHYTHMIA; HEART FUNCTION; HEART MUSCLE POTENTIAL; HUMAN; LONG QT SYNDROME; MEMBRANE DEPOLARIZATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; QT PROLONGATION; REPOLARIZATION; REVIEW; SODIUM CHANNELOPATHY; ST SEGMENT ELEVATION; T WAVE INVERSION; TORSADE DES POINTES;

ANIMALS; BRUGADA SYNDROME; HUMANS; ION CHANNEL GATING; LONG QT SYNDROME; MUTATION; SODIUM CHANNELS;

EID: 70049110216     PISSN: 19336950     EISSN: 19336969     Source Type: Journal    
DOI: 10.4161/chan.2.2.6000     Document Type: Review

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