A conserved ring of charge in mammalian Na+ channels: A molecular regulator of the outer pore conformation during slow inactivation

Journal of Physiology

Volumn 576, Issue 3, 2006, Pages 739-754

  Xiong, Wei ^a   Farukhi, Yousaf Z ^a   Tian, Yanli ^a   Disilvestre, Deborah ^a   Li, Ronald A ^a   Tomaselli, Gordon F ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; GLUTAMYLGLUTAMYLASPARTYLASPARTIC ACID; UNCLASSIFIED DRUG; VOLTAGE GATED SODIUM CHANNEL; SODIUM CHANNEL NAV1.4;

ACTION POTENTIAL; ANIMAL CELL; ARTICLE; CHANNEL GATING; CONTROLLED STUDY; ELECTRIC FIELD; ELECTROPHYSIOLOGY; MOLECULAR MODEL; MUTATION; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; REGULATORY MECHANISM; SITE DIRECTED MUTAGENESIS; ANIMAL TISSUE; BOLTZMANN EQUATION; CELL MEMBRANE POTENTIAL; CONFORMATION; FEMALE; HALF-INACTIVATION VOLTAGE; MATHEMATICAL ANALYSIS; POISSON DISTRIBUTION; PROTEIN MOTIF; PROTEIN STRUCTURE; STATIC ELECTRICITY; STEADY STATE; TRANSPORT KINETICS;

AMINO ACID MOTIFS; ANIMALS; FEMALE; ION CHANNEL GATING; MATHEMATICS; MEMBRANE POTENTIALS; MUTATION; OOCYTES; PATCH-CLAMP TECHNIQUES; PORINS; PROTEIN CONFORMATION; SODIUM CHANNELS; XENOPUS LAEVIS;

EID: 33750402366     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2006.115105     Document Type: Article

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