Relative resistance to slow inactivation of human cardiac Na+ channel hNav1.5 is reversed by lysine or glutamine substitution at V930 in D2-S6

American Journal of Physiology - Cell Physiology

Volumn 293, Issue 6, 2007, Pages

  Chancey, Jessica Hotard ^a   Shockett, Penny E ^a   O'Reilly, John P ^a  

^a SOUTHEASTERN LOUISIANA UNIVERSITY   (United States)

Author keywords

Site directed mutagenesis; Sodium channel; Voltage gating

Indexed keywords

CYSTEINE; GLUTAMINE; LYSINE; SODIUM CHANNEL; SODIUM CHANNEL NAV 1.5; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; CELL MEMBRANE DEPOLARIZATION; CONFORMATIONAL TRANSITION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HYDROPHOBICITY; HYPERPOLARIZATION; PATCH CLAMP; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; SODIUM CURRENT; STEADY STATE;

ACTION POTENTIALS; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CELL LINE; GLUTAMINE; HUMANS; LYSINE; MUSCLE PROTEINS; MUTAGENESIS, SITE-DIRECTED; PHENOTYPE; PROTEIN CONFORMATION; SODIUM CHANNELS;

EID: 37149001296     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00377.2007     Document Type: Article

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