Genotype-phenotype correlation in the long-QT syndrome: Gene-specific triggers for life-threatening arrhythmias

Circulation

Volumn 103, Issue 1, 2001, Pages 89-95

  Schwartz, Peter J ^a,o   Priori, Silvia G ^b   Spazzolini, Carla ^a   Moss, Arthur J ^c   Michael Vincent, G ^p   Napolitano, Carlo ^b   Denjoy, Isabelle ^e   Guicheney, Pascale ^f   Breithardt, Günter ^g   Keating, Mark T ^h   Towbin, Jeffrey A ⁱ   Beggs, Alan H ^j   Brink, Paul ^k   Wilde, Arthur A M ^l   Toivonen, Lauri ^m   Zareba, Wojciech ^c   Robinson, Jennifer L ^c   Timothy, Katherine W ^d   Corfield, Valerie ^k   Wattanasirichaigoon, Duangrurdee ^j   Corbett, Clive ^k   Haverkamp, Wilhelm ^g   Schulze Bahr, Eric ^g   Lehmann, Michael H ⁿ   Schwartz, Ketty ^f   Coumel, Philippe ^e   Bloise, Raffaella ^a   more..

^a UNIVERSITY OF PAVIA   (Italy)

^b IRCCS   (Italy)

^c UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^d UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^e HÔPITAL LARIBOISIÈRE   (France)

^f PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^g UNIVERSITY OF MÜNSTER   (Germany)

^h HOWARD HUGHES MEDICAL INSTITUTE   (United States)

ⁱ TEXAS CHILDREN S HOSPITAL   (United States)

^j BOSTON CHILDREN S HOSPITAL   (United States)

^k STELLENBOSCH UNIVERSITY   (South Africa)

^l ACADEMIC MEDICAL CENTER   (Netherlands)

^m UNIVERSITY OF HELSINKI   (Finland)

ⁿ UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^o FONDAZIONE IRCCS POLICLINICO SAN MATTEO   (Italy)

^p NONE

more..

Author keywords

Autonomic; Death, sudden; Genetics; Ion channels; Long QT syndrome; Nervous system

Indexed keywords

ADULT; ARRHYTHMOGENESIS; ARTICLE; CONTROLLED STUDY; EXERCISE; FATALITY; FEMALE; GENETIC RISK; GENOTYPE; HUMAN; LONG QT SYNDROME; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; PRIORITY JOURNAL; RISK FACTOR; SLEEP;

EID: 0035830365     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.103.1.89     Document Type: Article

References (20)

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8. Comparison of clinical and genetic variables of cardiac events associated with loud noise versus swimming among subjects with the long QT syndrome
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12. + channel blockade, β-adrenergic stimulation, and rapid pacing in a cellular model mimicking the SCN5A and HERG defects present in the long QT syndrome
13. Gene-specific differences in the circadian variation of ventricular repolarization in the long QT syndrome: A key to sudden death during sleep?
14. Cellular basis for the ECG features of the LQT1 form of the long QT syndrome: Effects of β-adrenergic agonists and antagonists and sodium channels blockers on transmural dispersion of repolarization and torsade de pointes
15. ECG T-wave patterns in genetically distinct forms of the hereditary long QT syndrome
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18. Effects of unilateral stellectomy upon cardiac performance during exercise in dogs
19. Auditory stimuli as a trigger for arrhythmic events differentiate HERG-related (LQTS2) patients from KvLQT1-related patients (LQTS1)