Induction of a reversible, non-cytotoxic S-phase delay by resveratrol: Implications for a mechanism of lifespan prolongation and cancer protection

British Journal of Pharmacology

Volumn 158, Issue 2, 2009, Pages 462-474

  Zhou, Ru ^a   Fukui, Masayuki ^a   Choi, Hye Joung ^a   Zhu, Bao Ting ^a  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

Cancer prevention; Cell cycle regulation; Lifespan prolongation; Resveratrol; S phase arrest

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 MORPHOLINO 8 PHENYLCHROMONE; CHECKPOINT KINASE 2; CYCLIN DEPENDENT KINASE 2; DIMETHYL SULFOXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; RESVERATROL;

APOPTOSIS; ARTICLE; CANCER PREVENTION; CELL CYCLE S PHASE; CELL DEATH; CELL DIVISION; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; DNA SYNTHESIS INHIBITION; DRUG MECHANISM; HUMAN; HUMAN CELL; HUMAN TISSUE; LIFE EXTENSION; LIVER CELL CARCINOMA; MITOCHONDRIAL RESPIRATION; PRIORITY JOURNAL;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CELL CYCLE; CELL LINE, TUMOR; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; LIVER NEOPLASMS; MEMBRANE POTENTIAL, MITOCHONDRIAL; S PHASE; SIGNAL TRANSDUCTION; STILBENES;

EID: 69549097739     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2009.00268.x     Document Type: Article

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