Resveratrol, a natural product present in wine, decreases tumour growth in a rat tumour model

Biochemical and Biophysical Research Communications

Volumn 254, Issue 3, 1999, Pages 739-743

  Carbó, Neus ^a   Costelli, Paola ^b   Baccino, Francesco M ^b,c   López Soriano, Francisco J ^a   Argilés, Josep M ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b UNIVERSITY OF TURIN   (Italy)

^c CNR   (Italy)

Author keywords

Apoptosis; Cancer; Chemotherapeutic potential; Resveratrol; Wine

Indexed keywords

RESVERATROL;

ANEUPLOIDY; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; ASCITES HEPATOMA; CANCER INHIBITION; CELL CYCLE; CELL CYCLE G2 PHASE; CONTROLLED STUDY; FLOW CYTOMETRY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; WINE;

EID: 0033608240     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.1998.9916     Document Type: Article

References (26)

1. Soleas G. J., Diamandis E. P., Goldberg D. M. Resveratrol: A molecule whose time has come? and gone. Clin. Biochem. 30:1997;91-113.
2. Siemann E. H., Creasy L. L. Concentration of the phytoalexin resveratrol in wine. Am. J. Enol. Vitic. 43:1992;49-52.
3. Maxwell S., Cruickshank A., Thorpe G. Red wine and antioxidant activity in serum. Lancet. 344:1994;193-194.
4. Whitehead T. P., Robinson D., Allaway S., Syms S., Hale A. Effect of red wine ingestion on antioxidant capacity of serum. Clin. Chem. 41:1995;32-35.
5. Ruf J. C., Berger J. L., Renaud S. Platelet rebound effect of alcohol withdrawal and wine drinking in rats. Relation to tannins and lipid peroxidation. Arterioscler. Thromb. Vasc. Biol. 1:1995;140-144.
6. Pace-Asciak C. R., Hahn S., Diamandis E. P., Soleas G., Goldberg D. M. The red wine phenolic trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: implications for protection against coronary heart disease. Clin. Chim. Acta. 235:1995;207-219.
7. Jang M., Cai L., Udeani G. O., Slowing K. V., Thomas C. F., Beecher C. W. W., Fong H. H. S., Farnsworth N. R., Kinghorn A. D., Menta R. G., Moon R. C., Pezzuto J. M. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science. 275:1997;218-220.
8. Subbaramauah K., Chung W. J., Michaluart P., Telang N., Tanabe T., Inoue H., Jang M., Pezzuto J. M., Dannenberg A. J. Resveratrol inhibits cyclooxygenase-2 transcription and activity in phorbol ester-treated human mammary epithelial cells. J. Biol. Chem. 273:1998;21875-21882.
9. Clifford A. J., Ebeler S. E., Ebeler J. D., Bills N. D., Hinrichs S. H., Teissedre P. L., Waterhouse A. L. Delayed tumour onset in transgenic mice fed an amino acid-based diet supplemented with red wine solids. Am. J. Clin. Nutr. 64:1996;748-756.
10. Tessitore L., Bonelli G., Baccino F. M. Early development of protein metabolic perturbations in the liver and skeletal muscle of tumour-bearing rats. Biochem. J. 241:1987;153-158.
11. Doll R., Peto R. The causes of cancer: Quantitative estimates of avoidable risks of cancer in the United States today. J. Natl. Cancer Inst. 66:1981;1191-1308.
12. Decker E. A. The role of phenolics, conjugated linoleic acid, carnosine and pyrroloquinoline quinone as nonessential dietary antioxidants. Nutr. Rev. 53:1995;49-58.
13. Romney S. L., Palan P. R., Basu J., Mikhail M. Nutrient antioxidants in the pathogenesis and prevention of cervical dysplasias and cancer. J. Cell. Biochem. 23:1995;96-103.
14. Shamon L. A., Chen C., Mehta R. G., Steele V., Moon R. C., Pezzuto J. M. A correlative approach for the identification of antimutagens that demonstrate chemopreventive activity. Anticancer Res. 14:1995;1775-1778.
15. Prochaska H. J., Santamaria A. B. Direct measurement of NAD(P)H:quinone reductase from cells cultured in microtiter wells: a screening assay for anticarcinogenic enzyme inducers. Anal. Biochem. 169:1988;328-336.
16. Zhang Y., Kensler T. W., Cho C. G., Posner G. H., Talalay P. Anticarcinogenic activities of sulforaphane and structurally related synthetic norbomyl isothiocyanates. Proc. Natl. Acad. Sci. USA. 91:1994;3147-3150.
17. Ragione F. D., Cucciolla V., Borriello A., Pietra V. D., Racioppi L., Soldati G., Manna C., Galletti P., Zappia V. Resveratrol arrests the cell division cycle at S/G2 phase transition. Biochem. Biophys. Res. Commun. 250:1998;53-58.
18. Clement M. V., Hirpara J. L., Chawdury S. H., Pervaiz S. Chemopreventive agent resveratrol, a natural product derived from grapes, triggers CD95 signaling-dependent apoptosis in human tumour cells. Blood. 92:1998;996-1002.
19. Tessitore L., Costelli P., Bonetti G., Baccino F. M. Cancer cachexia, malnutrition, and tissue protein turnover in experimental animals. Arch. Biochem. Biophys. 306:1993;52-58.
20. Tessitore L., Costelli P., Baccino F. M. Humoral mediation for cachexia in tumour-bearing rats. Br. J. Cancer. 67:1993;15-23.
21. Nicoletti I., Migliorati G., Pagliacci M. C., Grignani F., Riccardi C. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J. Immunol. Meth. 139:1991;271-279.
22. Barbiero G., Duranti F., Bonelli G., Amenta J. S., Baccino F. M. Intracellular ionic variations in the apoptotic deah ol L cells by inhibitors of cell cycle progression. Exp. Cell. Res. 217:1995;410-418.
23. Wu M. X., Prasad K. V., Wu R., Schlossman S. F. IEX-1L, an apoptosis inhibitor involved in nF-κB-mediated cell survival. Science. 14:1998;998-1001.
24. Wong S. C., Fukuchi M., Meinyk P., Rodger I., Giaid A. Induction of cyclooxygenase and activation of nuclear factor-kappaB in myocardium of patients with congestive heart failure. Circulation. 98:1998;100-103.
25. D'Acquisto F., Iuvone T., Rombola L., Sautebin L., Di-Rosa M., Carnuccio R. Involvement of NF-κB in the regulation of cyclooxygenase-2 protein expression in LPS-stimulated J774 macrophages. FEBS Lett. 418:1997;1-2.
26. Draczynska L. B., Chen Y. M., Sun A. Y. Oxidized lipoproteins activate NF-κB binding activity and apoptosis in PC12 cells. Neuroreport. 9:1998;527-532.