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Volumn 58, Issue 9, 2008, Pages 2786-2797

The antioxidant resveratrol protects against chondrocyte apoptosis via effects on mitochondrial polarization and ATP production

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANTIOXIDANT; COLLAGENASE 3; CYCLOOXYGENASE 2; CYTOCHROME C; INTERLEUKIN 1BETA; INTERSTITIAL COLLAGENASE; LEUKOTRIENE B4; LIPOCORTIN 5; MATRIX METALLOPROTEINASE; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE; PROTEOGLYCAN; RESVERATROL; STROMELYSIN;

EID: 51849141393     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.23799     Document Type: Article
Times cited : (124)

References (51)
  • 1
    • 0034971296 scopus 로고    scopus 로고
    • Osteoarthritis, an inflammatory disease: Potential implication for the selection of new therapeutic targets [review]
    • Pelletier JP, Martel-Pelletier J, Abramson SB. Osteoarthritis, an inflammatory disease: potential implication for the selection of new therapeutic targets [review]. Arthritis Rheum 2001;44:1237-47.
    • (2001) Arthritis Rheum , vol.44 , pp. 1237-1247
    • Pelletier, J.P.1    Martel-Pelletier, J.2    Abramson, S.B.3
  • 2
    • 22544432235 scopus 로고    scopus 로고
    • Interleukin-1β induces death in chondrocyte-like ATDC5 cells through mitochondrial dysfunction and energy depletion in a reactive nitrogen and oxygen species-dependent manner
    • Yasuhara R, Miyamoto Y, Akaike T, Akuta T, Nakamura M, Takami M, et al. Interleukin-1β induces death in chondrocyte-like ATDC5 cells through mitochondrial dysfunction and energy depletion in a reactive nitrogen and oxygen species-dependent manner. Biochem J 2005;389(Pt 2):315-23.
    • (2005) Biochem J , vol.389 , Issue.PART 2 , pp. 315-323
    • Yasuhara, R.1    Miyamoto, Y.2    Akaike, T.3    Akuta, T.4    Nakamura, M.5    Takami, M.6
  • 3
    • 0036210361 scopus 로고    scopus 로고
    • Invited review: The mitochondrion in osteoarthritis [review]
    • Terkeltaub R, Johnson K, Murphy A, Ghosh S. Invited review: the mitochondrion in osteoarthritis [review]. Mitochondrion 2002;1:301-19.
    • (2002) Mitochondrion , vol.1 , pp. 301-319
    • Terkeltaub, R.1    Johnson, K.2    Murphy, A.3    Ghosh, S.4
  • 4
    • 34548451974 scopus 로고    scopus 로고
    • Reactive oxygen species in mitochondria-mediated cell death
    • Orrenius S. Reactive oxygen species in mitochondria-mediated cell death. Drug Metab Rev 2007;39:443-55.
    • (2007) Drug Metab Rev , vol.39 , pp. 443-455
    • Orrenius, S.1
  • 5
    • 26444473434 scopus 로고    scopus 로고
    • Potential involvement of oxidative stress in cartilage senescence and development of osteoarthritis: Oxidative stress induces chondrocyte telomere instability and downregulation of chondrocyte function
    • Yudoh K, Nguyen T, Nakamura H, Hongo-Masuko K, Kato T, Nishioka K. Potential involvement of oxidative stress in cartilage senescence and development of osteoarthritis: oxidative stress induces chondrocyte telomere instability and downregulation of chondrocyte function. Arthritis Res Ther 2005;7:R380-91.
    • (2005) Arthritis Res Ther , vol.7
    • Yudoh, K.1    Nguyen, T.2    Nakamura, H.3    Hongo-Masuko, K.4    Kato, T.5    Nishioka, K.6
  • 6
    • 33746734833 scopus 로고    scopus 로고
    • Resveratrol modulation of signal transduction in apoptosis and cell survival: A mini-review
    • Fulda S, Debatin KM. Resveratrol modulation of signal transduction in apoptosis and cell survival: a mini-review. Cancer Detect Prev 2006;30:217-23.
    • (2006) Cancer Detect Prev , vol.30 , pp. 217-223
    • Fulda, S.1    Debatin, K.M.2
  • 7
    • 33646068410 scopus 로고    scopus 로고
    • Resveratrol as a chemopreventive agent: A promising molecule for fighting cancer
    • Delmas D, Lancon A, Colin D, Jannin B, Latruffe N. Resveratrol as a chemopreventive agent: a promising molecule for fighting cancer. Curr Drug Targets 2006;7:423-42.
    • (2006) Curr Drug Targets , vol.7 , pp. 423-442
    • Delmas, D.1    Lancon, A.2    Colin, D.3    Jannin, B.4    Latruffe, N.5
  • 8
    • 0037082355 scopus 로고    scopus 로고
    • The "French Paradox" and beyond: Neuroprotective effects of polyphenols
    • Sun AY, Simonyi A, Sun GY. The "French Paradox" and beyond: neuroprotective effects of polyphenols. Free Radic Biol Med 2002;32:314-8.
    • (2002) Free Radic Biol Med , vol.32 , pp. 314-318
    • Sun, A.Y.1    Simonyi, A.2    Sun, G.Y.3
  • 9
    • 33745962138 scopus 로고    scopus 로고
    • Therapeutic potential of resveratrol: The in vivo evidence
    • Baur JA, Sinclair DA. Therapeutic potential of resveratrol: the in vivo evidence. Nat Rev Drug Discov 2006;5:493-506.
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 493-506
    • Baur, J.A.1    Sinclair, D.A.2
  • 10
    • 33845399894 scopus 로고    scopus 로고
    • Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1α
    • Lagouge M, Argmann C, Gerhart-Hines Z, Meziane H, Lerin C, Daussin F, et al. Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1α. Cell 2006;127:1109-22.
    • (2006) Cell , vol.127 , pp. 1109-1122
    • Lagouge, M.1    Argmann, C.2    Gerhart-Hines, Z.3    Meziane, H.4    Lerin, C.5    Daussin, F.6
  • 11
    • 0033129760 scopus 로고    scopus 로고
    • Inhibitory effect of resveratrol on interleukin 6 release by stimulated peritoneal macrophages of mice
    • Zhong M, Cheng GF, Wang WJ, Guo Y, Zhu XY, Zhang JT. Inhibitory effect of resveratrol on interleukin 6 release by stimulated peritoneal macrophages of mice. Phytomedicine 1999;6:79-84.
    • (1999) Phytomedicine , vol.6 , pp. 79-84
    • Zhong, M.1    Cheng, G.F.2    Wang, W.J.3    Guo, Y.4    Zhu, X.Y.5    Zhang, J.T.6
  • 12
    • 0033559420 scopus 로고    scopus 로고
    • Inhibitory effects of resveratrol analogs on unopsonized zymosan-induced oxygen radical production
    • Jang DS, Kang BS, Ryu SY, Chang IM, Min KR, Kim Y. Inhibitory effects of resveratrol analogs on unopsonized zymosan-induced oxygen radical production. Biochem Pharmacol 1999;57:705-12.
    • (1999) Biochem Pharmacol , vol.57 , pp. 705-712
    • Jang, D.S.1    Kang, B.S.2    Ryu, S.Y.3    Chang, I.M.4    Min, K.R.5    Kim, Y.6
  • 14
    • 0033917861 scopus 로고    scopus 로고
    • Resveratrol modulates arachidonic acid release, prostaglandin synthesis, and 3T6 fibroblast growth
    • Moreno JJ. Resveratrol modulates arachidonic acid release, prostaglandin synthesis, and 3T6 fibroblast growth. J Pharmacol Exp Ther 2000;294:333-8.
    • (2000) J Pharmacol Exp Ther , vol.294 , pp. 333-338
    • Moreno, J.J.1
  • 15
    • 0034105743 scopus 로고    scopus 로고
    • Suppression of cyclooxygenase-2 promoter-dependent transcriptional activity in colon cancer cells by chemopreventive agents with a resorcin-type structure
    • Mutoh M, Takahashi M, Fukuda K, Matsushima-Hibiya Y, Mutoh H, Sugimura T, et al. Suppression of cyclooxygenase-2 promoter-dependent transcriptional activity in colon cancer cells by chemopreventive agents with a resorcin-type structure. Carcinogenesis 2000;21:959-63.
    • (2000) Carcinogenesis , vol.21 , pp. 959-963
    • Mutoh, M.1    Takahashi, M.2    Fukuda, K.3    Matsushima-Hibiya, Y.4    Mutoh, H.5    Sugimura, T.6
  • 16
    • 33644688231 scopus 로고    scopus 로고
    • Dealcoholized red wine containing known amounts of resveratrol suppresses atherosclerosis in hypercholesterolemic rabbits without affecting plasma lipid levels
    • Wang Z, Zou J, Cao K, Hsieh TC, Huang Y, Wu JM. Dealcoholized red wine containing known amounts of resveratrol suppresses atherosclerosis in hypercholesterolemic rabbits without affecting plasma lipid levels. Int J Mol Med 2005;16:533-40.
    • (2005) Int J Mol Med , vol.16 , pp. 533-540
    • Wang, Z.1    Zou, J.2    Cao, K.3    Hsieh, T.C.4    Huang, Y.5    Wu, J.M.6
  • 17
    • 33747886389 scopus 로고    scopus 로고
    • Resveratrol - a boon for treating Alzheimer's disease?
    • Anekonda TS. Resveratrol - a boon for treating Alzheimer's disease? Brain Res Rev 2006;52:316-26.
    • (2006) Brain Res Rev , vol.52 , pp. 316-326
    • Anekonda, T.S.1
  • 19
    • 0034704070 scopus 로고    scopus 로고
    • Reversal of autocrine and paracrine effects of interleukin 1 (IL-1) in human arthritis by type II IL-1 decoy receptor: Potential for pharmacological intervention
    • Attur MG, Dave M, Cipolletta C, Kang P, Goldring MB, Patel IR, et al. Reversal of autocrine and paracrine effects of interleukin 1 (IL-1) in human arthritis by type II IL-1 decoy receptor: potential for pharmacological intervention. J Biol Chem 2000;275:40307-15.
    • (2000) J Biol Chem , vol.275 , pp. 40307-40315
    • Attur, M.G.1    Dave, M.2    Cipolletta, C.3    Kang, P.4    Goldring, M.B.5    Patel, I.R.6
  • 22
  • 24
    • 0019431577 scopus 로고
    • a cartilage catabolic factor from synovium
    • Dingle JT. Catabolin - a cartilage catabolic factor from synovium. Clin Orthop Relat Res 1981;156:219-31.
    • (1981) Clin Orthop Relat Res , vol.156 , pp. 219-231
    • Catabolin, D.J.T.1
  • 25
    • 0021858830 scopus 로고
    • Articular cartilage cultured with catabolin (pig interleukin 1) synthesizes a decreased number of normal proteoglycan molecules
    • Tyler JA. Articular cartilage cultured with catabolin (pig interleukin 1) synthesizes a decreased number of normal proteoglycan molecules. Biochem J 1985;227:869-78.
    • (1985) Biochem J , vol.227 , pp. 869-878
    • Tyler, J.A.1
  • 26
    • 33745041925 scopus 로고    scopus 로고
    • Caspase inhibitors reduce severity of cartilage lesions in experimental osteoarthritis
    • D'Lima D, Hermida J, Hashimoto S, Colwell C, Lotz M. Caspase inhibitors reduce severity of cartilage lesions in experimental osteoarthritis. Arthritis Rheum 2006;54:1814-21.
    • (2006) Arthritis Rheum , vol.54 , pp. 1814-1821
    • D'Lima, D.1    Hermida, J.2    Hashimoto, S.3    Colwell, C.4    Lotz, M.5
  • 27
    • 3242666996 scopus 로고    scopus 로고
    • Mechanism of superoxide-mediated damage relevance to mitochondrial aging
    • Afanas'Ev IB. Mechanism of superoxide-mediated damage relevance to mitochondrial aging. Ann N Y Acad Sci 2004;1019:343-5.
    • (2004) Ann N Y Acad Sci , vol.1019 , pp. 343-345
    • Afanas'Ev, I.B.1
  • 28
    • 34250901592 scopus 로고    scopus 로고
    • Phase I dose escalation pharmacokinetic study in healthy volunteers of resveratrol, a potential cancer chemopreventive agent
    • Boocock DJ, Faust GE, Patel KR, Schinas AM, Brown VA, Ducharme MP, et al. Phase I dose escalation pharmacokinetic study in healthy volunteers of resveratrol, a potential cancer chemopreventive agent. Cancer Epidemiol Biomarkers Prev 2007;16:1246-52.
    • (2007) Cancer Epidemiol Biomarkers Prev , vol.16 , pp. 1246-1252
    • Boocock, D.J.1    Faust, G.E.2    Patel, K.R.3    Schinas, A.M.4    Brown, V.A.5    Ducharme, M.P.6
  • 29
    • 5444238022 scopus 로고    scopus 로고
    • The role of cytokines in cartilage matrix degeneration in osteoarthritis
    • Goldring SR, Goldring MB. The role of cytokines in cartilage matrix degeneration in osteoarthritis. Clin Orthop Relat Res 2004;(427 Suppl):S27-36.
    • (2004) Clin Orthop Relat Res , vol.427 , Issue.SUPPL.
    • Goldring, S.R.1    Goldring, M.B.2
  • 30
    • 18244385249 scopus 로고    scopus 로고
    • Wieland HA, Michaelis M, Kirschbaum BJ, Rudolphi KA. Osteoarthritis - an untreatable disease? [published erratum appears in Nat Rev Drug Discov 2005;4:543]. Nat Rev Drug Discov 2005;4:331-44.
    • Wieland HA, Michaelis M, Kirschbaum BJ, Rudolphi KA. Osteoarthritis - an untreatable disease? [published erratum appears in Nat Rev Drug Discov 2005;4:543]. Nat Rev Drug Discov 2005;4:331-44.
  • 31
    • 0034566271 scopus 로고    scopus 로고
    • Amin AR, Dave M, Attur M, Abramson SB. COX-2, NO, and cartilage damage and repair. Curr Rheumatol Rep 2000;2:447-53.
    • Amin AR, Dave M, Attur M, Abramson SB. COX-2, NO, and cartilage damage and repair. Curr Rheumatol Rep 2000;2:447-53.
  • 32
    • 3542996841 scopus 로고    scopus 로고
    • Resveratrol inhibits cyclooxygenase-2 transcription and activity in phorbol ester-treated human mammary epithelial cells
    • Subbaramaiah K, Chung WJ, Michaluart P, Telang N, Tanabe T, Inoue H, et al. Resveratrol inhibits cyclooxygenase-2 transcription and activity in phorbol ester-treated human mammary epithelial cells. J Biol Chem 1998;273:21875-82.
    • (1998) J Biol Chem , vol.273 , pp. 21875-21882
    • Subbaramaiah, K.1    Chung, W.J.2    Michaluart, P.3    Telang, N.4    Tanabe, T.5    Inoue, H.6
  • 33
    • 0032096324 scopus 로고    scopus 로고
    • Paradoxical effects of resveratrol on the two prostaglandin H synthases
    • Johnson JL, Maddipati KR. Paradoxical effects of resveratrol on the two prostaglandin H synthases. Prostaglandins Other Lipid Mediat 1998;56:131-43.
    • (1998) Prostaglandins Other Lipid Mediat , vol.56 , pp. 131-143
    • Johnson, J.L.1    Maddipati, K.R.2
  • 34
    • 0031561513 scopus 로고    scopus 로고
    • Cancer chemopreventive activity of resveratrol, a natural product derived from grapes
    • Jang M, Cai L, Udeani GO, Slowing KV, Thomas CF, Beecher CW, et al. Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science 1997;275:218-20.
    • (1997) Science , vol.275 , pp. 218-220
    • Jang, M.1    Cai, L.2    Udeani, G.O.3    Slowing, K.V.4    Thomas, C.F.5    Beecher, C.W.6
  • 35
    • 33645717235 scopus 로고    scopus 로고
    • The protective effect of licofelone on experimental osteoarthritis is correlated with the downregulation of gene expression and protein synthesis of several major cartilage catabolic factors: MMP-13, cathepsin K and aggrecanases
    • Pelletier JP, Boileau C, Boily M, Brunet J, Mineau F, Geng C, et al. The protective effect of licofelone on experimental osteoarthritis is correlated with the downregulation of gene expression and protein synthesis of several major cartilage catabolic factors: MMP-13, cathepsin K and aggrecanases. Arthritis Res Ther 2005;7:R1091-102.
    • (2005) Arthritis Res Ther , vol.7
    • Pelletier, J.P.1    Boileau, C.2    Boily, M.3    Brunet, J.4    Mineau, F.5    Geng, C.6
  • 36
    • 0003133991 scopus 로고    scopus 로고
    • Resveratrol prevents apoptosis in K562 cells by inhibiting lipoxygenase and cyclooxygenase activity
    • MacCarrone M, Lorenzon T, Guerrieri P, Agro AF. Resveratrol prevents apoptosis in K562 cells by inhibiting lipoxygenase and cyclooxygenase activity. Eur J Biochem 1999;265:27-34.
    • (1999) Eur J Biochem , vol.265 , pp. 27-34
    • MacCarrone, M.1    Lorenzon, T.2    Guerrieri, P.3    Agro, A.F.4
  • 37
    • 3843092892 scopus 로고    scopus 로고
    • Regulation of metalloproteinases and NF-κB activation in rabbit synovial fibroblasts via E prostaglandins and Erk: Contrasting effects of nabumetone and 6MNA
    • Pillinger MH, Dinsell V, Apsel B, Tolani SN, Marjanovic N, Chan ES, et al. Regulation of metalloproteinases and NF-κB activation in rabbit synovial fibroblasts via E prostaglandins and Erk: contrasting effects of nabumetone and 6MNA. Br J Pharmacol 2004;142:973-82.
    • (2004) Br J Pharmacol , vol.142 , pp. 973-982
    • Pillinger, M.H.1    Dinsell, V.2    Apsel, B.3    Tolani, S.N.4    Marjanovic, N.5    Chan, E.S.6
  • 38
    • 0034909954 scopus 로고    scopus 로고
    • Effects of non-steroidal antiinflammatory drugs and dexamethasone on the activity and expression of matrix metalloproteinase-1, matrix metalloproteinase-3 and tissue inhibitor of metalloproteinases-1 by bovine articular chondrocytes
    • Sadowski T, Steinmeyer J. Effects of non-steroidal antiinflammatory drugs and dexamethasone on the activity and expression of matrix metalloproteinase-1, matrix metalloproteinase-3 and tissue inhibitor of metalloproteinases-1 by bovine articular chondrocytes. Osteoarthritis Cartilage 2001;9:407-15.
    • (2001) Osteoarthritis Cartilage , vol.9 , pp. 407-415
    • Sadowski, T.1    Steinmeyer, J.2
  • 40
    • 1842482424 scopus 로고    scopus 로고
    • Resveratrol inhibits phorbol myristate acetate-induced matrix metalloproteinase-9 expression by inhibiting JNK and PKC-δ signal transduction
    • Woo JH, Lim JH, Kim YH, Suh SI, Min DS, Chang JS, et al. Resveratrol inhibits phorbol myristate acetate-induced matrix metalloproteinase-9 expression by inhibiting JNK and PKC-δ signal transduction. Oncogene 2004;23:1845-53.
    • (2004) Oncogene , vol.23 , pp. 1845-1853
    • Woo, J.H.1    Lim, J.H.2    Kim, Y.H.3    Suh, S.I.4    Min, D.S.5    Chang, J.S.6
  • 41
    • 33847194975 scopus 로고    scopus 로고
    • Cell death and apoptosis in osteoarthritic cartilage
    • Kim HA, Blanco FJ. Cell death and apoptosis in osteoarthritic cartilage. Curr Drug Targets 2007;8:333-45.
    • (2007) Curr Drug Targets , vol.8 , pp. 333-345
    • Kim, H.A.1    Blanco, F.J.2
  • 43
    • 28844488347 scopus 로고    scopus 로고
    • Resveratrol protects against cold ischemia-warm reoxygenation-induced damages to mitochondria and cells in rat liver
    • Plin C, Tillement JP, Berdeaux A, Morin D. Resveratrol protects against cold ischemia-warm reoxygenation-induced damages to mitochondria and cells in rat liver. Eur J Pharmacol 2005;528:162-8.
    • (2005) Eur J Pharmacol , vol.528 , pp. 162-168
    • Plin, C.1    Tillement, J.P.2    Berdeaux, A.3    Morin, D.4
  • 44
    • 37849041521 scopus 로고    scopus 로고
    • Regulation of inflammation signalling by resveratrol in human chondrocytes in vitro
    • Csaki C, Keshishzadeh N, Fischer K, Shakibaei M. Regulation of inflammation signalling by resveratrol in human chondrocytes in vitro. Biochem Pharmacol 2008;75:677-87.
    • (2008) Biochem Pharmacol , vol.75 , pp. 677-687
    • Csaki, C.1    Keshishzadeh, N.2    Fischer, K.3    Shakibaei, M.4
  • 45
    • 34247880271 scopus 로고    scopus 로고
    • Resveratrol inhibits IL-1β-induced stimulation of caspase-3 and cleavage of PARP in human articular chondrocytes in vitro
    • Shakibaei M, John T, Seifarth C, Mobasheri A. Resveratrol inhibits IL-1β-induced stimulation of caspase-3 and cleavage of PARP in human articular chondrocytes in vitro. Ann N Y Acad Sci 2007;1095:554-63.
    • (2007) Ann N Y Acad Sci , vol.1095 , pp. 554-563
    • Shakibaei, M.1    John, T.2    Seifarth, C.3    Mobasheri, A.4
  • 51
    • 33750839605 scopus 로고    scopus 로고
    • Resveratrol interferes with AKT activity and triggers apoptosis in human uterine cancer cells
    • Sexton E, Van Themsche C, Leblanc K, Parent S, Lemoine P, Asselin E. Resveratrol interferes with AKT activity and triggers apoptosis in human uterine cancer cells. Mol Cancer 2006;5:45.
    • (2006) Mol Cancer , vol.5 , pp. 45
    • Sexton, E.1    Van Themsche, C.2    Leblanc, K.3    Parent, S.4    Lemoine, P.5    Asselin, E.6


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