Suppressor of cytokine signalling-3 inhibits tumor necrosis factor-alpha induced apoptosis and signalling in beta cells

Molecular and Cellular Endocrinology

Volumn 311, Issue 1-2, 2009, Pages 32-38

  Bruun, Christine ^a   Heding, Peter E ^a   Rønn, Sif G ^a   Frobøse, Helle ^a   Rhodes, Christopher J ^b   Mandrup Poulsen, Thomas ^a,c   Billestrup, Nils ^a  

^a HAGEDORN RESEARCH INSTITUTE   (Denmark)

^b UNIVERSITY OF CHICAGO   (United States)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

I B; INS 1 beta cells; MAP kinase; NF B; Rat islets; SOCS 3; T1DM; TNF

Indexed keywords

DNA; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MANGANESE SUPEROXIDE DISMUTASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; STRESS ACTIVATED PROTEIN KINASE; SUPPRESSOR OF CYTOKINE SIGNALING 3; SYNAPTOPHYSIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DNA BINDING; DRUG TARGETING; GENE EXPRESSION; HUMAN; HUMAN CELL; INHIBITION KINETICS; INSULIN DEPENDENT DIABETES MELLITUS; NEWBORN; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS INHIBITION; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; DNA; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION REGULATION; HUMANS; I-KAPPA B PROTEINS; INSULIN-SECRETING CELLS; INTERLEUKIN-1BETA; MICE; MIDDLE AGED; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 69449089392     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mce.2009.07.019     Document Type: Article

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