Pyridoxal 5′-phosphate inactivates DNA topoisomerase IB by modifying the lysine general acid

Nucleic Acids Research

Volumn 32, Issue 18, 2004, Pages 5649-5657

  Vermeersh, Jacqueline J ^a   Christmann Franck, Serge ^b,c   Karabashyan, Leon V ^d   Fermandjian, Serge ^b   Mirambeau, Gilles ^e   Der Garabedian, P Arsène ^a  

^a SORBONNE UNIVERSITÉ   (France)

^b UNIVERSITÉ PARIS SACLAY   (France)

^c Accelrys   (France)

^d INSTITUTE OF MOLECULAR BIOLOGY   (Armenia)

^e INSTITUT GUSTAVE ROUSSY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DNA TOPOISOMERASE; LYSINE; PYRIDOXAL 5 PHOSPHATE; ADENOSINE DIPHOSPHATE; ADENOSINE DIPHOSPHATE PYRIDOXAL; DRUG DERIVATIVE; ENZYME INHIBITOR; PYRIDOXAL 5'-DIPHOSPHO-5'-ADENOSINE;

AMINO ACID SEQUENCE; ARTICLE; CANDIDA ALBICANS; CANDIDA GUILLIERMONDII; CHEMICAL STRUCTURE; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTALLOGRAPHY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES POMBE; BINDING SITE; CHEMISTRY; DRUG EFFECT; HUMAN; METABOLISM;

CANDIDA ALBICANS; HOMO SAPIENS; PICHIA GUILLIERMONDII; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES POMBE;

ADENOSINE DIPHOSPHATE; BINDING SITES; DNA TOPOISOMERASES, TYPE I, EUKARYOTIC; ENZYME INHIBITORS; HUMANS; LYSINE; MODELS, MOLECULAR; PYRIDOXAL PHOSPHATE;

EID: 6944232331     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/gkh897     Document Type: Article

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