cAMP stringently regulates human cathelicidin antimicrobial peptide expression in the mucosal epithelial cells by activating cAMP-response element-binding protein, AP-1, and inducible cAMP early repressor

Journal of Biological Chemistry

Volumn 284, Issue 33, 2009, Pages 21810-21827

  Chakraborty, Krishnendu ^a   Maity, Palash Chandra ^b   Sil, Alok Kumar ^b   Takeda, Yoshifumi ^a   Das, Santasabuj ^a  

^a NATIONAL INSTITUTE OF CHOLERA AND ENTERIC DISEASES   (India)

^b UNIVERSITY OF CALCUTTA   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATOR PROTEIN-1; ANTIMICROBIAL PEPTIDE; CAMP-RESPONSE ELEMENT-BINDING PROTEINS; CATHELICIDIN; CIS-ACTING ELEMENT; ELEMENT-BINDING PROTEINS; EPITHELIAL CELLS; HEPATITIS B VIRUS; HOST DEFENSE; IN-VITRO; INDUCIBLE EXPRESSION; INTESTINAL EPITHELIAL CELLS; MECHANISTIC STUDIES; MUCOSAL SURFACE; REGULATORY MECHANISM; REGULATORY SEQUENCES; SIGNALING PATHWAYS; SODIUM BUTYRATE; TRANSCRIPTIONAL COMPLEXES;

AMINES; BLOOD VESSEL PROSTHESES; CELLS; CHEMICAL ACTIVATION; FETAL MONITORING; LAWS AND LEGISLATION; PEPTIDES; SODIUM;

POLYPEPTIDES;

BUTYRIC ACID; CATHELICIDIN; COMPLEMENTARY DNA; CYCLIC AMP; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; HEPATITIS B VIRUS X PROTEIN; INDUCIBLE CYCLIC AMP EARLY REPRESSOR; MESSENGER RNA; POLYPEPTIDE ANTIBIOTIC AGENT; REPRESSOR PROTEIN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

ARTICLE; CELL FRACTIONATION; CELL NUCLEUS; CELL STIMULATION; CELL STRAIN HT29; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CYTOPLASM; DNA SYNTHESIS; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM CELL; GEL MOBILITY SHIFT ASSAY; GENE SILENCING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOMODULATION; MOLECULAR CLONING; MUCOSA; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN SYNTHESIS REGULATION; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY MECHANISM; RNA EXTRACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UPREGULATION;

ANTIMICROBIAL CATIONIC PEPTIDES; CACO-2 CELLS; CELL LINE, TUMOR; CYCLIC AMP; CYCLIC AMP RESPONSE ELEMENT MODULATOR; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; HUMANS; MODELS, GENETIC; MUCOUS MEMBRANE; PROMOTER REGIONS, GENETIC; PROTEIN STRUCTURE, TERTIARY; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1;

BACTERIA (MICROORGANISMS); HEPATITIS B VIRUS;

EID: 69249098510     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.001180     Document Type: Article

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