-
1
-
-
0031569528
-
Genetically engineered nontoxic vaccine adjuvant that combines B cell targeting with immunomodulation by cholera toxin A1 subunit
-
Ågren, L.C., Ekman, L., Löwenadler, L. & Lycke, N.Y. (1997), Genetically engineered nontoxic vaccine adjuvant that combines B cell targeting with immunomodulation by cholera toxin A1 subunit. J. Immunol, 158, 3936-3946.
-
(1997)
J. Immunol
, vol.158
, pp. 3936-3946
-
-
Ågren, L.C.1
Ekman, L.2
Löwenadler, L.3
Lycke, N.Y.4
-
2
-
-
0025091644
-
Effects of cholera toxin on human B cells: Cholera toxin induces B cell surface DR expression while it inhibits anti-μ antibody-induced cell proliferation
-
Anastassiou, E.D., Yamada, H., Francis, M.L., Mond, J.J. & Tsokos, G.C. (1990), Effects of cholera toxin on human B cells: cholera toxin induces B cell surface DR expression while it inhibits anti-μ antibody-induced cell proliferation. J. Immunol., 145, 2375-2380.
-
(1990)
J. Immunol.
, vol.145
, pp. 2375-2380
-
-
Anastassiou, E.D.1
Yamada, H.2
Francis, M.L.3
Mond, J.J.4
Tsokos, G.C.5
-
3
-
-
0024314197
-
Cholera toxin inhibits resting human T cell activation via a cAMP-independent pathway
-
Anderson, D.L. & Tsoukas, C.D. (1989), Cholera toxin inhibits resting human T cell activation via a cAMP-independent pathway. J. Immunol., 143, 3647-3652.
-
(1989)
J. Immunol.
, vol.143
, pp. 3647-3652
-
-
Anderson, D.L.1
Tsoukas, C.D.2
-
4
-
-
0030752473
-
Mucosal immunization with DNA encoding influenza hemagglutinin
-
Ban, E.M., van Ginkel, F.W., Simecka, J.W., Kiyono, H., Robinson, H.L. & McGhee, J.R. (1997), Mucosal immunization with DNA encoding influenza hemagglutinin. Vaccine, 15, 811-813.
-
(1997)
Vaccine
, vol.15
, pp. 811-813
-
-
Ban, E.M.1
Van Ginkel, F.W.2
Simecka, J.W.3
Kiyono, H.4
Robinson, H.L.5
McGhee, J.R.6
-
5
-
-
0028927443
-
Local and systemic antibody responses to dextran-cholera toxin B subunit conjugates
-
Bergquist, C., Lagergård, T., Lindblad, M. & Holmgren, J. (1995), Local and systemic antibody responses to dextran-cholera toxin B subunit conjugates. Infect. Immun., 63, 2021-2025.
-
(1995)
Infect. Immun.
, vol.63
, pp. 2021-2025
-
-
Bergquist, C.1
Lagergård, T.2
Lindblad, M.3
Holmgren, J.4
-
6
-
-
0030952626
-
A nasal whole-cell pertussis vaccine can induce strong systemic and mucosal antibody responses which are not enhanced by cholera toxin
-
Berstad, A.K., Holst, J., Mogster, B., Haugen, I.L. & Haneberg, B. (1997), A nasal whole-cell pertussis vaccine can induce strong systemic and mucosal antibody responses which are not enhanced by cholera toxin. Vaccine, 15, 1473-1478.
-
(1997)
Vaccine
, vol.15
, pp. 1473-1478
-
-
Berstad, A.K.1
Holst, J.2
Mogster, B.3
Haugen, I.L.4
Haneberg, B.5
-
7
-
-
0010642492
-
Recombinant cholera B subunit is not an effective mucosal adjuvant for oral immunization of mice against H. Felis
-
in press
-
Blanchard, T.G., Lycke, N., Czinn, S.J. & Nedrud, J. (1997), Recombinant cholera B subunit is not an effective mucosal adjuvant for oral immunization of mice against H. felis. Immunology, in press.
-
(1997)
Immunology
-
-
Blanchard, T.G.1
Lycke, N.2
Czinn, S.J.3
Nedrud, J.4
-
8
-
-
0028803530
-
Peritoneal macrophages from C57B1/6 mice orally immunized with Toxoplasma gondii antigens in association with cholera toxin possess an enhanced ability to inhibit parasite multiplication
-
Bourguin, I., Chardes, T. & Bout, D. (1995), Peritoneal macrophages from C57B1/6 mice orally immunized with Toxoplasma gondii antigens in association with cholera toxin possess an enhanced ability to inhibit parasite multiplication. FEMS Immunol. Med. Microbiol., 12, 121-126.
-
(1995)
FEMS Immunol. Med. Microbiol.
, vol.12
, pp. 121-126
-
-
Bourguin, I.1
Chardes, T.2
Bout, D.3
-
9
-
-
0028049032
-
Cholera toxin acts as a potent adjuvant for the induction of cytotoxic T-lymphocyte responses with nonreplicating antigens
-
Bowen, J.C., Nair, S.K., Reddy, R. & Rouse, B.T. (1994), Cholera toxin acts as a potent adjuvant for the induction of cytotoxic T-lymphocyte responses with nonreplicating antigens. Immunology, 81, 338-342.
-
(1994)
Immunology
, vol.81
, pp. 338-342
-
-
Bowen, J.C.1
Nair, S.K.2
Reddy, R.3
Rouse, B.T.4
-
10
-
-
0029934454
-
IL-6 deficient mice exhibit normal IgA responses to local immunizations and Helicobacter felis infection
-
Bromander, A.K., Ekman, L., Kopf, M., Nedrud, J. & Lycke, N. (1996), IL-6 deficient mice exhibit normal IgA responses to local immunizations and Helicobacter felis infection. J. Immunol., 156, 4290-4298.
-
(1996)
J. Immunol.
, vol.156
, pp. 4290-4298
-
-
Bromander, A.K.1
Ekman, L.2
Kopf, M.3
Nedrud, J.4
Lycke, N.5
-
11
-
-
0025735374
-
Cholera toxin stimulates IL-1 production and enhances antigen-presentation by macrophages in vitro
-
Bromander, A.K., Holmgren, J. & Lycke, N. (1991), Cholera toxin stimulates IL-1 production and enhances antigen-presentation by macrophages in vitro. J. Immunol., 146, 2908-2929.
-
(1991)
J. Immunol.
, vol.146
, pp. 2908-2929
-
-
Bromander, A.K.1
Holmgren, J.2
Lycke, N.3
-
12
-
-
0027468206
-
Cholera toxin enhances alloantigen-presentation by cultured intestinal epithelial cells
-
Bromander, A.K., Holmgren, J. & Lycke, N. (1993), Cholera toxin enhances alloantigen-presentation by cultured intestinal epithelial cells. Scand. J. Immunol., 37, 452-458.
-
(1993)
Scand. J. Immunol.
, vol.37
, pp. 452-458
-
-
Bromander, A.K.1
Holmgren, J.2
Lycke, N.3
-
13
-
-
0026005836
-
Site-specific mutagenisis of the catalytic subunit of cholera toxin: Substituting lysine for arginine 7 causes loss of activity
-
Burnette, N., Mar, V.L., Platler, W., Schlotterbeck, D., McGinley, D., Stoney, S., Rhode, S.M.F. & Kaslow, H.R. (1991), Site-specific mutagenisis of the catalytic subunit of cholera toxin: substituting lysine for arginine 7 causes loss of activity. Infect. Immun., 59, 4266-4270.
-
(1991)
Infect. Immun.
, vol.59
, pp. 4266-4270
-
-
Burnette, N.1
Mar, V.L.2
Platler, W.3
Schlotterbeck, D.4
McGinley, D.5
Stoney, S.6
Rhode, S.M.F.7
Kaslow, H.R.8
-
14
-
-
0028113922
-
A quantitative analysis of antigen-presenting cell function; activated B cells stimulate naive CD4 T cells but are inferior to dendritic cells in providing co-stimulation
-
Cassell, D.J. & Schwartz, R.H. (1994), A quantitative analysis of antigen-presenting cell function; activated B cells stimulate naive CD4 T cells but are inferior to dendritic cells in providing co-stimulation. J. Exp. Med., 180, 1829-1837.
-
(1994)
J. Exp. Med.
, vol.180
, pp. 1829-1837
-
-
Cassell, D.J.1
Schwartz, R.H.2
-
15
-
-
0025022340
-
Cholera holotoxin and its B subunit enhance Peyer's patch B-cell responses induced by orally administered influenza virus: Disproportionate cholera toxin enhancement of the IgA B cell response
-
Chen, K.-S. & Strober, W. (1990), Cholera holotoxin and its B subunit enhance Peyer's patch B-cell responses induced by orally administered influenza virus: disproportionate cholera toxin enhancement of the IgA B cell response. Eur. J. Immunol., 20, 433-436.
-
(1990)
Eur. J. Immunol.
, vol.20
, pp. 433-436
-
-
Chen, K.-S.1
Strober, W.2
-
16
-
-
0025809436
-
Mucosal priming of T-lymphocyte responses to fed protein antigens using cholera toxin as an adjuvant
-
Clarke, C.J., Wilson, A.D., Williams, N.A. & Stokes, C.R. (1991), Mucosal priming of T-lymphocyte responses to fed protein antigens using cholera toxin as an adjuvant. Immunology, 72, 323-328.
-
(1991)
Immunology
, vol.72
, pp. 323-328
-
-
Clarke, C.J.1
Wilson, A.D.2
Williams, N.A.3
Stokes, C.R.4
-
17
-
-
0031296660
-
The mucosal adjuvanticity of cholera toxin involves enhancement of co-stimulatory activity by selective up-regulation of B-7.2 expression
-
Cong, Y., Weaver, C.T. & Elson, C.O. (1997), The mucosal adjuvanticity of cholera toxin involves enhancement of co-stimulatory activity by selective up-regulation of B-7.2 expression. J. Immunol., 159, 5301-5308.
-
(1997)
J. Immunol.
, vol.159
, pp. 5301-5308
-
-
Cong, Y.1
Weaver, C.T.2
Elson, C.O.3
-
19
-
-
0015795679
-
Gangliosides and membrane receptors for cholera toxin
-
Cuatrecasas, P. (1973), Gangliosides and membrane receptors for cholera toxin. Biochemistry, 12, 3558-3566.
-
(1973)
Biochemistry
, vol.12
, pp. 3558-3566
-
-
Cuatrecasas, P.1
-
20
-
-
0024565465
-
Oral administration of a streptococcal antigen coupled to cholera toxin B subunit evokes strong antibody responses in salivary glands and extramucosal tissues
-
Czerkinsky, C., Russell, M.W., Lycke, N., Lindblad, M. & Holmgren, J. (1989), Oral administration of a streptococcal antigen coupled to cholera toxin B subunit evokes strong antibody responses in salivary glands and extramucosal tissues. Infect. Immun., 57, 1072-1077.
-
(1989)
Infect. Immun.
, vol.57
, pp. 1072-1077
-
-
Czerkinsky, C.1
Russell, M.W.2
Lycke, N.3
Lindblad, M.4
Holmgren, J.5
-
21
-
-
0019293278
-
Amino acid sequence homology between cholera toxin and Escherichia coli heat-labile toxin
-
Dallas, W.S. & Falkow, S. (1980), Amino acid sequence homology between cholera toxin and Escherichia coli heat-labile toxin. Nature, 288, 499-501.
-
(1980)
Nature
, vol.288
, pp. 499-501
-
-
Dallas, W.S.1
Falkow, S.2
-
22
-
-
0028985871
-
Dissociation of Escherichia coli heat-labile enterotoxin adjuvanticity from ADP-ribosyltransferase activity
-
Dickinson, B.L. & Clements, J.D. (1995), Dissociation of Escherichia coli heat-labile enterotoxin adjuvanticity from ADP-ribosyltransferase activity. Infect. Immun., 63, 1617-1623.
-
(1995)
Infect. Immun.
, vol.63
, pp. 1617-1623
-
-
Dickinson, B.L.1
Clements, J.D.2
-
23
-
-
0030940814
-
Intranasal immunogenicity and adjuvanticity of site-directed mutant derivates of cholera toxin
-
Douce, G., Fontana, M., Pizza, M., Rappuoli, R. & Dougan, G. (1997), Intranasal immunogenicity and adjuvanticity of site-directed mutant derivates of cholera toxin. Infect. Immun., 65, 2821-2828.
-
(1997)
Infect. Immun.
, vol.65
, pp. 2821-2828
-
-
Douce, G.1
Fontana, M.2
Pizza, M.3
Rappuoli, R.4
Dougan, G.5
-
24
-
-
0028918767
-
Mutants of Escherichia coli heat-labile toxin lacking ADP-ribosyltransferase activity act as non-toxic, mucosal adjuvants
-
Douce, G., Turcotte, C., Cropley, I., Roberts, M., Pizza, M., Domenghini, M., Rappuoli, R. & Dougan, G. (1995), Mutants of Escherichia coli heat-labile toxin lacking ADP-ribosyltransferase activity act as non-toxic, mucosal adjuvants. Proc. Natl. Acad. Sci. USA, 92, 1644-1648.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 1644-1648
-
-
Douce, G.1
Turcotte, C.2
Cropley, I.3
Roberts, M.4
Pizza, M.5
Domenghini, M.6
Rappuoli, R.7
Dougan, G.8
-
25
-
-
0021260553
-
Generalized systemic and mucosal immunity in mice after mucosal stimulation with cholera toxin
-
Elson, C.O. & Ealding, W. (1984a), Generalized systemic and mucosal immunity in mice after mucosal stimulation with cholera toxin. J. Immunol., 132, 2736-2741.
-
(1984)
J. Immunol.
, vol.132
, pp. 2736-2741
-
-
Elson, C.O.1
Ealding, W.2
-
26
-
-
0021681145
-
Cholera toxin feeding did not induce oral tolerance and abrogated oral tolerance to an unrelated protein antigen
-
Elson, C.O. & Ealding, W. (1984b), Cholera toxin feeding did not induce oral tolerance and abrogated oral tolerance to an unrelated protein antigen. J. Immunol., 133, 2892-2897.
-
(1984)
J. Immunol.
, vol.133
, pp. 2892-2897
-
-
Elson, C.O.1
Ealding, W.2
-
28
-
-
0028815662
-
Morphologic and functional alterations of mucosal T cells by cholera toxin and its B subunit
-
Elson, C.O., Holland, S.P., Dertzbaugh, M.T., Cuff, C.F. & Anderson, A.O. (1995), Morphologic and functional alterations of mucosal T cells by cholera toxin and its B subunit. J. Immunol., 154, 1032-1039.
-
(1995)
J. Immunol.
, vol.154
, pp. 1032-1039
-
-
Elson, C.O.1
Holland, S.P.2
Dertzbaugh, M.T.3
Cuff, C.F.4
Anderson, A.O.5
-
29
-
-
0030837792
-
Class I-restricted CTL induction by mucosal immunization with naked DNA encoding measels virus haemagglutinin
-
Etchart, N., Buckland, R., Liu, M.A., Wild, T.F. & Kaiserlian, D. (1997), Class I-restricted CTL induction by mucosal immunization with naked DNA encoding measels virus haemagglutinin. J. Gen. Virol., 78, 1577-1580.
-
(1997)
J. Gen. Virol.
, vol.78
, pp. 1577-1580
-
-
Etchart, N.1
Buckland, R.2
Liu, M.A.3
Wild, T.F.4
Kaiserlian, D.5
-
30
-
-
0029041926
-
cAMP-independent effects of cholera toxin on B cell activation. III. Cholera toxin A subunit-mediated ADP-ribosylation acts synergistically with ionomycin or IL-4 to induce B cell proliferation
-
Francis, M.L., Okazaki, I., Moss, J., Kurosky, A., Pecanha, L.M. & Mond, J.J. (1995), cAMP-independent effects of cholera toxin on B cell activation. III. Cholera toxin A subunit-mediated ADP-ribosylation acts synergistically with ionomycin or IL-4 to induce B cell proliferation. J. Immunol., 154, 4956-4964.
-
(1995)
J. Immunol.
, vol.154
, pp. 4956-4964
-
-
Francis, M.L.1
Okazaki, I.2
Moss, J.3
Kurosky, A.4
Pecanha, L.M.5
Mond, J.J.6
-
31
-
-
0026554220
-
Cyclic AMP-independent effects of cholera toxin on B cell activation. II. Binding of ganglioside GM1 induces B cell activation
-
Francis, M.L., Ryan, J., Jobling, M.G., Holmes, R.K., Moss, J. & Mond, J. (1992), Cyclic AMP-independent effects of cholera toxin on B cell activation. II. Binding of ganglioside GM1 induces B cell activation. J. Immunol., 148, 1999-2005.
-
(1992)
J. Immunol.
, vol.148
, pp. 1999-2005
-
-
Francis, M.L.1
Ryan, J.2
Jobling, M.G.3
Holmes, R.K.4
Moss, J.5
Mond, J.6
-
32
-
-
0029787628
-
Role of the glycocalyx in regulating access of microparticles to apical plasma membranes of intestinal epithelial cells: Implications for microbial attachment and oral vaccine targeting
-
Frey, A., Giannasca, K.T., Weltzin, R., Giannasca, P.J., Reggio, H., Lencer, W.I. & Neutra, M.R. (1996), Role of the glycocalyx in regulating access of microparticles to apical plasma membranes of intestinal epithelial cells: implications for microbial attachment and oral vaccine targeting. J. Exp. Med., 184, 1045-1059.
-
(1996)
J. Exp. Med.
, vol.184
, pp. 1045-1059
-
-
Frey, A.1
Giannasca, K.T.2
Weltzin, R.3
Giannasca, P.J.4
Reggio, H.5
Lencer, W.I.6
Neutra, M.R.7
-
33
-
-
0031134566
-
CD28 dependence of T cell differentiation to IL-4 production varies with the particular type 2 immune response
-
Gause, W.C., Chen, S.J., Greenwald, R.J., Halvorson, M.J., Lu, P., Zhou, X.d., Morris, S.C., Lee, K.P., June, C.H., Finkelman, F.D., Urban, J.F. & Abe, R. (1997a), CD28 dependence of T cell differentiation to IL-4 production varies with the particular type 2 immune response. J. Immunol., 158, 4082.
-
(1997)
J. Immunol.
, vol.158
, pp. 4082
-
-
Gause, W.C.1
Chen, S.J.2
Greenwald, R.J.3
Halvorson, M.J.4
Lu, P.5
Zhou, X.D.6
Morris, S.C.7
Lee, K.P.8
June, C.H.9
Finkelman, F.D.10
Urban, J.F.11
Abe, R.12
-
34
-
-
0031106557
-
The function of costimulatory molecules and the development of IL-4-producing T cells
-
Gause, W.C., Halvorson, M.J., Lu, P., Greenwald, R., Linsley, P., Urban, J.F. & Finkelman, F.D. (1997b), The function of costimulatory molecules and the development of IL-4-producing T cells. Immunol. Today, 18, 115.
-
(1997)
Immunol. Today
, vol.18
, pp. 115
-
-
Gause, W.C.1
Halvorson, M.J.2
Lu, P.3
Greenwald, R.4
Linsley, P.5
Urban, J.F.6
Finkelman, F.D.7
-
35
-
-
0028128355
-
Role of trypsin-like cleavage at arginine 192 in the enzymatic and cytotonic activities of Escherichia coli heat-labile enterotoxin
-
Grant, C.C.R., Messer, R.J. & Cieplak, W. (1994), Role of trypsin-like cleavage at arginine 192 in the enzymatic and cytotonic activities of Escherichia coli heat-labile enterotoxin. Infect. Immun., 62, 4270-4278.
-
(1994)
Infect. Immun.
, vol.62
, pp. 4270-4278
-
-
Grant, C.C.R.1
Messer, R.J.2
Cieplak, W.3
-
36
-
-
0028198825
-
Memory B cell development but not germinal center formation is impaired by in vivo blockade of CD40-CD40 ligand interaction
-
Gray, D., Dullforce, P. & Jainandinsing, S. (1994), Memory B cell development but not germinal center formation is impaired by in vivo blockade of CD40-CD40 ligand interaction. J. Exp. Med., 180, 141-155.
-
(1994)
J. Exp. Med.
, vol.180
, pp. 141-155
-
-
Gray, D.1
Dullforce, P.2
Jainandinsing, S.3
-
38
-
-
0027207218
-
Cholera toxin inhibits T cell receptor signalling by covalent modification of the CD3-ζ subunit
-
Haack, B.M., Emmrich, F. & Resch, K. (1993), Cholera toxin inhibits T cell receptor signalling by covalent modification of the CD3-ζ subunit. J. Immunol., 150, 2599-2606.
-
(1993)
J. Immunol.
, vol.150
, pp. 2599-2606
-
-
Haack, B.M.1
Emmrich, F.2
Resch, K.3
-
39
-
-
0029805948
-
Mutants of the Escherichia coli heat-labile enterotoxin with reduced ADP-ribosylation activity or no activity retain the immunogenic properties of the native holotoxin
-
De Haan, L., Verweij, W.R., Feil, I.K., Lijnema, T.H., Hol, W.G.J., Agsterribbe, E. & Wilschut, J. (1996), Mutants of the Escherichia coli heat-labile enterotoxin with reduced ADP-ribosylation activity or no activity retain the immunogenic properties of the native holotoxin. Infect. Immun., 64, 5413-5416.
-
(1996)
Infect. Immun.
, vol.64
, pp. 5413-5416
-
-
De Haan, L.1
Verweij, W.R.2
Feil, I.K.3
Lijnema, T.H.4
Hol, W.G.J.5
Agsterribbe, E.6
Wilschut, J.7
-
40
-
-
0030176041
-
Oral immunization with a model protein entrapped in microspheres prepared from derivatized alpha-ammo acids
-
Haas, S., Miura-Fraboni, J., Zavala, F., Murata, K., Leone-Bay, A. & Santiago, N. (1996), Oral immunization with a model protein entrapped in microspheres prepared from derivatized alpha-ammo acids. Vaccine, 14, 785-791.
-
(1996)
Vaccine
, vol.14
, pp. 785-791
-
-
Haas, S.1
Miura-Fraboni, J.2
Zavala, F.3
Murata, K.4
Leone-Bay, A.5
Santiago, N.6
-
41
-
-
0029036648
-
Mucosal immunization with a bacterial protein antigen genetically coupled to cholera toxin A2/B Subunits
-
Hajishengallis, G., Hollingshead, S.K., Koga, T. & Russell, M.W. (1994), Mucosal immunization with a bacterial protein antigen genetically coupled to cholera toxin A2/B Subunits. J. Immunol., 154, 4322-4332.
-
(1994)
J. Immunol.
, vol.154
, pp. 4322-4332
-
-
Hajishengallis, G.1
Hollingshead, S.K.2
Koga, T.3
Russell, M.W.4
-
42
-
-
0027336689
-
+ T cells through IL-12 produced by Listeria-induced macrophages
-
+ T cells through IL-12 produced by Listeria-induced macrophages. Science, 260, 547-549.
-
(1993)
Science
, vol.260
, pp. 547-549
-
-
Hsieh, C.S.1
Macatonia, S.E.2
Tripp, C.S.3
Wolf, S.F.4
O'Garra, A.5
Murphy, K.M.6
-
43
-
-
0027291977
-
Cholera toxin adjuvant strongly promotes T cell priming
-
Hörnqvist, E. & Lycke, N. (1993), Cholera toxin adjuvant strongly promotes T cell priming. Eur. J. Immunol., 23, 2136-2143.
-
(1993)
Eur. J. Immunol.
, vol.23
, pp. 2136-2143
-
-
Hörnqvist, E.1
Lycke, N.2
-
44
-
-
0029049417
-
Paradoxical IgA immunity in CD4-deficient mice. Lack of cholera toxin-specific protective immunity despite normal gut mucosal iga differentiation
-
Hörnquist, E., Ekman, L., Grdic, D., Schön, K. & Lycke, N. (1995), Paradoxical IgA immunity in CD4-deficient mice. Lack of cholera toxin-specific protective immunity despite normal gut mucosal IgA differentiation. J. Immunol., 155, 2877-2885.
-
(1995)
J. Immunol.
, vol.155
, pp. 2877-2885
-
-
Hörnquist, E.1
Ekman, L.2
Grdic, D.3
Schön, K.4
Lycke, N.5
-
45
-
-
0030023828
-
CD8-deficient mice exhibit augmented mucosal immune responses and intact adjuvant effect of cholera toxin
-
Hörnquist, E., Grdic, D., Mak, T. & Lycke, N. (1996), CD8-deficient mice exhibit augmented mucosal immune responses and intact adjuvant effect of cholera toxin. Immunology, 87, 220-228.
-
(1996)
Immunology
, vol.87
, pp. 220-228
-
-
Hörnquist, E.1
Grdic, D.2
Mak, T.3
Lycke, N.4
-
46
-
-
0011062958
-
Cholera toxin inhibits the T-cell antigen receptor-mediated increases in inositol trisphospate and cytoplasmic free calcium
-
Imboden, J.B., Shoback, D.M., Pattison, G. & Stobo, J.D. (1986), Cholera toxin inhibits the T-cell antigen receptor-mediated increases in inositol trisphospate and cytoplasmic free calcium. Proc. Natl. Acad. Sci. USA, 83, 5673-5677.
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 5673-5677
-
-
Imboden, J.B.1
Shoback, D.M.2
Pattison, G.3
Stobo, J.D.4
-
47
-
-
0027453689
-
Optimizing oral vaccines: Induction of systemic and mucosal B-cell and antibody responses to tetanus toxoid by use of cholera toxin as an adjuvant
-
Jackson, R.J., Fujihashi, K., Xu-Amano, J., Kiyono, H., Elson, C.O. & McGhee, J.R. (1993), Optimizing oral vaccines: induction of systemic and mucosal B-cell and antibody responses to tetanus toxoid by use of cholera toxin as an adjuvant. Infect. Immun., 61, 4272-4279.
-
(1993)
Infect. Immun.
, vol.61
, pp. 4272-4279
-
-
Jackson, R.J.1
Fujihashi, K.2
Xu-Amano, J.3
Kiyono, H.4
Elson, C.O.5
McGhee, J.R.6
-
48
-
-
0030820364
-
Interferon-γ receptor-deficient mice exhibit impaired gut mucosal immune responses but intact oral tolerance
-
Kjerrulf, M., Grdic, D., Ekman, L., Schön, K. & Lycke, N. (1997), Interferon-γ receptor-deficient mice exhibit impaired gut mucosal immune responses but intact oral tolerance. Immunology, 92, 60-68.
-
(1997)
Immunology
, vol.92
, pp. 60-68
-
-
Kjerrulf, M.1
Grdic, D.2
Ekman, L.3
Schön, K.4
Lycke, N.5
-
49
-
-
0027452977
-
Disruption of the murine IL-4 gene blocks Th2 cytokine responses
-
Kopf, M., Le Gros, G., Bachmann, M., Lamers, M.C., Bluethmann, H. & Köhler, G. (1993), Disruption of the murine IL-4 gene blocks Th2 cytokine responses. Nature, 362, 245-248.
-
(1993)
Nature
, vol.362
, pp. 245-248
-
-
Kopf, M.1
Le Gros, G.2
Bachmann, M.3
Lamers, M.C.4
Bluethmann, H.5
Köhler, G.6
-
50
-
-
0030932988
-
Induction of mucosal immunity against herpes simplex virus by plasmid DNA immunization
-
Kuklin, N., Daheshia, M., Karem, E., Manickan, E. & Rouse, B.T. (1997), Induction of mucosal immunity against herpes simplex virus by plasmid DNA immunization. J. Virol., 71, 3138-3145.
-
(1997)
J. Virol.
, vol.71
, pp. 3138-3145
-
-
Kuklin, N.1
Daheshia, M.2
Karem, E.3
Manickan, E.R.B.T.4
-
51
-
-
0028094771
-
+ T cells while decreasing IL-2 release and NF-AT induction
-
+ T cells while decreasing IL-2 release and NF-AT induction. Int. Immunol., 9, 1333-1340.
-
(1994)
Int. Immunol.
, vol.9
, pp. 1333-1340
-
-
Lacour, M.1
Arrighi, J.-F.2
Muller, K.M.3
Carlberg, C.4
Saurat, J.-H.5
Hauser, C.6
-
52
-
-
0028153996
-
B cell function in mice transgenic for mCTLA4-Hgl: Lack of germinal centers correlated with poor affinity maturation and class switching despite normal priming of CD4+ T cells
-
Lane, P., Burdet, C., Hubele, S., Schedegger, D., Muller, U., McConell, F. & Kosco-Vilbois, M. (1994), B cell function in mice transgenic for mCTLA4-Hgl: lack of germinal centers correlated with poor affinity maturation and class switching despite normal priming of CD4+ T cells. J. Exp. Med., 179, 819-826.
-
(1994)
J. Exp. Med.
, vol.179
, pp. 819-826
-
-
Lane, P.1
Burdet, C.2
Hubele, S.3
Schedegger, D.4
Muller, U.5
McConell, F.6
Kosco-Vilbois, M.7
-
53
-
-
0021058990
-
New knowledge on pathogenesis of bacterial enteric infections as applied to vaccine development
-
Levine, M.M., Kaper, J.B., Black, R.E. & Clemens, M.L. (1983), New knowledge on pathogenesis of bacterial enteric infections as applied to vaccine development. Microbiol. Rev., 47, 510.
-
(1983)
Microbiol. Rev.
, vol.47
, pp. 510
-
-
Levine, M.M.1
Kaper, J.B.2
Black, R.E.3
Clemens, M.L.4
-
54
-
-
0030444083
-
Cholera toxin B subunit binding to an antigen-presenting cell directly co-stimulates cytokine production from a T cell clone
-
Li, T.-K. & Fox, B.S. (1996), Cholera toxin B subunit binding to an antigen-presenting cell directly co-stimulates cytokine production from a T cell clone. Int. Immunol., 8, 1849-1856.
-
(1996)
Int. Immunol.
, vol.8
, pp. 1849-1856
-
-
Li, T.-K.1
Fox, B.S.2
-
55
-
-
0023724502
-
Oral administration of cholera toxin Sendai virus conjugate potentiates gut and respiratory immunity against sendai virus
-
Liang, X., Lamm, M.E. & Nedrud, J.G. (1988), Oral administration of cholera toxin Sendai virus conjugate potentiates gut and respiratory immunity against Sendai virus. J. Immunol., 141, 1495-1501.
-
(1988)
J. Immunol.
, vol.141
, pp. 1495-1501
-
-
Liang, X.1
Lamm, M.E.2
Nedrud, J.G.3
-
56
-
-
0024322169
-
Cholera toxin as a mucosal adjuvant: Glutaraldehyde-treatment dissociates adjuvanticity from toxicity
-
Liang, X., Lamm, M.E. & Nedrud, J.G. (1989), Cholera toxin as a mucosal adjuvant: glutaraldehyde-treatment dissociates adjuvanticity from toxicity. J. Immunol., 143, 484-490.
-
(1989)
J. Immunol.
, vol.143
, pp. 484-490
-
-
Liang, X.1
Lamm, M.E.2
Nedrud, J.G.3
-
57
-
-
0027488503
-
2: Separation of affinity from specificity
-
2: separation of affinity from specificity. Mol. Immunol., 14, 1279-1285.
-
(1993)
Mol. Immunol.
, vol.14
, pp. 1279-1285
-
-
Ljungberg, U.K.1
Jansson, B.2
Niss, U.3
Nilsson, R.4
Sandberg, B.5
Nilsson, B.6
-
58
-
-
0028141008
-
Fusion proteins with heterologous T helper epitopes. Recombinant E. Coli heat-stable enterotoxin proteins
-
Löwenadler, B. & Lycke, N. (1994), Fusion proteins with heterologous T helper epitopes. Recombinant E. coli heat-stable enterotoxin proteins. Int. Rev. Immunol., 11, 103-111.
-
(1994)
Int. Rev. Immunol.
, vol.11
, pp. 103-111
-
-
Löwenadler, B.1
Lycke, N.2
-
59
-
-
0027174861
-
Cholera toxin promotes B cell isotype switching by two different mechanisms: cAMP-induction augments germline Ig H-chain RNA transcripts whereas membrane ganglioside GM1-receptor binding enhances later events in differentiation
-
Lycke, N. (1993), Cholera toxin promotes B cell isotype switching by two different mechanisms: cAMP-induction augments germline Ig H-chain RNA transcripts whereas membrane ganglioside GM1-receptor binding enhances later events in differentiation. J. Immunol., 150, 4810-4821.
-
(1993)
J. Immunol.
, vol.150
, pp. 4810-4821
-
-
Lycke, N.1
-
60
-
-
0010687078
-
A molecular approach to the construction of an effective mucosal vaccine adjuvant: Studies based on cholera toxin ADP-ribosylation and cell targeting
-
(M.F. Kagnoff and H. Kiyono) Academic press, San Diego
-
Lycke, N. (1996), A molecular approach to the construction of an effective mucosal vaccine adjuvant: studies based on cholera toxin ADP-ribosylation and cell targeting, in "Essentials of mucosal immunology" (M.F. Kagnoff and H. Kiyono) (p. 563). Academic press, San Diego.
-
(1996)
Essentials of Mucosal Immunology
, pp. 563
-
-
Lycke, N.1
-
61
-
-
0022460378
-
Strong adjuvant properties of cholera toxin on gut mucosal immune responses to orally presented antigens
-
Lycke, N. & Holmgren, J. (1986), Strong adjuvant properties of cholera toxin on gut mucosal immune responses to orally presented antigens. Immunology, 59, 301-308.
-
(1986)
Immunology
, vol.59
, pp. 301-308
-
-
Lycke, N.1
Holmgren, J.2
-
62
-
-
0023635901
-
Long-term cholera antitoxin memory in the gut can be triggered to antibody formation associated with protection within hours after an oral challenge immunization
-
Lycke, N. & Holmgren, J. (1987), Long-term cholera antitoxin memory in the gut can be triggered to antibody formation associated with protection within hours after an oral challenge immunization. Scand. J. Immunol., 25, 407-412.
-
(1987)
Scand. J. Immunol.
, vol.25
, pp. 407-412
-
-
Lycke, N.1
Holmgren, J.2
-
63
-
-
0024381404
-
Cholera toxin promotes B cell isotype differentiation
-
Lycke, N. & Strober, W. (1989), Cholera toxin promotes B cell isotype differentiation. J. Immunol., 142, 3781-3787.
-
(1989)
J. Immunol.
, vol.142
, pp. 3781-3787
-
-
Lycke, N.1
Strober, W.2
-
64
-
-
0024513124
-
Adoptive transfer of gut mucosal antitoxin memory by isolated B cells one year after oral immunization with cholera toxin
-
Lycke, N. & Holmgren, J. (1989), Adoptive transfer of gut mucosal antitoxin memory by isolated B cells one year after oral immunization with cholera toxin. Infect. Immun., 57, 1137-1141.
-
(1989)
Infect. Immun.
, vol.57
, pp. 1137-1141
-
-
Lycke, N.1
Holmgren, J.2
-
65
-
-
0024493771
-
Cellular basis of immunomodulation by cholera toxin in vitro with possible association to the adjuvant function in vivo
-
Lycke, N., Bromander, A.K., Ekman, L., Karlsson, U. & Holmgren, J. (1989), Cellular basis of immunomodulation by cholera toxin in vitro with possible association to the adjuvant function in vivo. J. Immunol., 142, 20-27.
-
(1989)
J. Immunol.
, vol.142
, pp. 20-27
-
-
Lycke, N.1
Bromander, A.K.2
Ekman, L.3
Karlsson, U.4
Holmgren, J.5
-
66
-
-
0001768410
-
Presentation of immunogens at the gut and other mucosal surfaces
-
(Woodrow, M. Levine) Marcel Dekker Inc., NY.
-
Lycke, N. & Svennerholm, A.-M. (1990), Presentation of immunogens at the gut and other mucosal surfaces, in "The Molecular Approach To New And Improved Vaccines" (Woodrow, M. Levine) (pp. 207-227). Marcel Dekker Inc., NY.
-
(1990)
The Molecular Approach to New and Improved Vaccines
, pp. 207-227
-
-
Lycke, N.1
Svennerholm, A.-M.2
-
67
-
-
0025823778
-
Molecular effects of cholera toxin on isotype differentiation
-
Lycke, N., Severinson, E. & Strober, W. (1991a), Molecular effects of cholera toxin on isotype differentiation. Immunol. Res., 10, 407-412.
-
(1991)
Immunol. Res.
, vol.10
, pp. 407-412
-
-
Lycke, N.1
Severinson, E.2
Strober, W.3
-
68
-
-
0025204725
-
Cholera toxin acts synergistically with IL-4 to promote IgG1 switch differentiation
-
Lycke, N., Severinson, E. & Strober, W. (1991b), Cholera toxin acts synergistically with IL-4 to promote IgG1 switch differentiation. J. Immunol., 145, 3316-3324.
-
(1991)
J. Immunol.
, vol.145
, pp. 3316-3324
-
-
Lycke, N.1
Severinson, E.2
Strober, W.3
-
69
-
-
0025819246
-
The adjuvant action of cholera toxin is associated with an increased intestinal permeability for luminal antigens
-
Lycke, N., Karlsson, U., Sjölander, A. & Magnusson, K.-E. (1991c), The adjuvant action of cholera toxin is associated with an increased intestinal permeability for luminal antigens. Scand. J. Immunol., 33, 691-698.
-
(1991)
Scand. J. Immunol.
, vol.33
, pp. 691-698
-
-
Lycke, N.1
Karlsson, U.2
Sjölander, A.3
Magnusson, K.-E.4
-
70
-
-
0026699224
-
The adjuvant effect of Vibrio cholerae and E. Coli heat labile enterotoxins is linked to their ADP-ribosyltransferase activity
-
Lycke, N., Tsuji, T. & Holmgren, J. (1992), The adjuvant effect of Vibrio cholerae and E. coli heat labile enterotoxins is linked to their ADP-ribosyltransferase activity. Eur. J. Immunol., 22, 2277-2281.
-
(1992)
Eur. J. Immunol.
, vol.22
, pp. 2277-2281
-
-
Lycke, N.1
Tsuji, T.2
Holmgren, J.3
-
71
-
-
0029852233
-
Mutations in the A subunit affect yield, stability, and protease sensitivity of nontoxic derivates of heat-labile enterotoxin
-
Magagnoli, C., Manetti, R., Fontana, M.R., Gianelli, V., Giuliani, M.M., Rappuoli, R. & Pizza, M. (1996), Mutations in the A subunit affect yield, stability, and protease sensitivity of nontoxic derivates of heat-labile enterotoxin. Infect. Immun., 64, 5434-5438.
-
(1996)
Infect. Immun.
, vol.64
, pp. 5434-5438
-
-
Magagnoli, C.1
Manetti, R.2
Fontana, M.R.3
Gianelli, V.4
Giuliani, M.M.5
Rappuoli, R.6
Pizza, M.7
-
72
-
-
0031041232
-
Oral but not parenteral interleukin (IL)-12 redirects T helper 2 (Th2)-type responses to an oral vaccine without altering mucosal IgA responses
-
Marinaro, M., Boyaka, P.N., Finkelman, F.D., Kiyono, H., Jackson, R.J., Jirillo, E. & McGhee, J.R. (1997), Oral but not parenteral interleukin (IL)-12 redirects T helper 2 (Th2)-type responses to an oral vaccine without altering mucosal IgA responses. J. Exp. Med., 3, 415-427.
-
(1997)
J. Exp. Med.
, vol.3
, pp. 415-427
-
-
Marinaro, M.1
Boyaka, P.N.2
Finkelman, F.D.3
Kiyono, H.4
Jackson, R.J.5
Jirillo, E.6
McGhee, J.R.7
-
73
-
-
0028807596
-
Mucosal adjuvant effect of cholera toxin in mice results from induction of T helper 2 (Th2) cells and IL-4
-
Marinaro, M., Staats, H.F., Hiroi, T., Jackson, R.J., Coste, M., Boyaka, P.N., Okahashi, N., Yamamoto, M., Kiyono, H., Bluethmann, H., Fujihashi, K. & McGhee, J.R. (1995), Mucosal adjuvant effect of cholera toxin in mice results from induction of T helper 2 (Th2) cells and IL-4. J. Immunol., 155, 4621-4629.
-
(1995)
J. Immunol.
, vol.155
, pp. 4621-4629
-
-
Marinaro, M.1
Staats, H.F.2
Hiroi, T.3
Jackson, R.J.4
Coste, M.5
Boyaka, P.N.6
Okahashi, N.7
Yamamoto, M.8
Kiyono, H.9
Bluethmann, H.10
Fujihashi, K.M.J.R.11
-
74
-
-
0030010957
-
Distinct effects of recombinant cholera toxin B subunit and holotoxin on different stages of class II MHC antigen processing and presentation by macrophages
-
Matousek, M.P., Nedrud, J.G. & Harding, C.V. (1996), Distinct effects of recombinant cholera toxin B subunit and holotoxin on different stages of class II MHC antigen processing and presentation by macrophages. J. Immunol., 156, 4137-4145.
-
(1996)
J. Immunol.
, vol.156
, pp. 4137-4145
-
-
Matousek, M.P.1
Nedrud, J.G.2
Harding, C.V.3
-
75
-
-
0027427572
-
Enhancing effect of cholera toxin on interleukin-6 secretion by IEC-6 intestinal epithelial cells: Mode of action and augmenting effect of inflammatory cytokines
-
McGee, D.W., Elson, C.O. & McGhee, J.R. (1993), Enhancing effect of cholera toxin on interleukin-6 secretion by IEC-6 intestinal epithelial cells: mode of action and augmenting effect of inflammatory cytokines. Infect. Immun., 61, 4637-4644.
-
(1993)
Infect. Immun.
, vol.61
, pp. 4637-4644
-
-
McGee, D.W.1
Elson, C.O.2
McGhee, J.R.3
-
76
-
-
0028267231
-
M1 pentasaccharide
-
M1 pentasaccharide. Prot. Sci., 3, 166.
-
(1994)
Prot. Sci.
, vol.3
, pp. 166
-
-
Merritt, E.A.1
Sarfaty, S.2
Van Den Akker, F.3
L'Hoir, C.4
Martial, J.A.5
Hol, W.G.6
-
77
-
-
0001324363
-
Oral immunization of H. Pylori infected adults with recombinant urease and LT adjuvant
-
Michetti, P., Kreiss, C., Kotloff, K., Porta, N., Blanco, J.L., Bachman, D., Sadlinger, P.F., Corthesy-Theulaz, I., Losonsky, G., Nichols, R., Stolte, M., Monath, T., Ackerman, S. & Blum (1997), Oral immunization of H. pylori infected adults with recombinant urease and LT adjuvant (Abstract). Gastroenterology, 112:A1042.
-
(1997)
Gastroenterology
, vol.112
-
-
Michetti, P.1
Kreiss, C.2
Kotloff, K.3
Porta, N.4
Blanco, J.L.5
Bachman, D.6
Sadlinger, P.F.7
Corthesy-Theulaz, I.8
Losonsky, G.9
Nichols, R.10
Stolte, M.11
Monath, T.12
Ackerman, S.13
-
78
-
-
0002000895
-
Oral tolerance and regulation of immunity to dietary antigens
-
(P. Ogra, J. Metscky, M. Lamm, W. Strober, J. McGhee, and J. Bienenstock) Academic Press, San Diego
-
Mowat, A. (1994), Oral tolerance and Regulation of Immunity to dietary antigens, in "Handbook of Mucosal Immunology" (P. Ogra, J. Metscky, M. Lamm, W. Strober, J. McGhee, and J. Bienenstock) (pp. 185-202). Academic Press, San Diego.
-
(1994)
Handbook of Mucosal Immunology
, pp. 185-202
-
-
Mowat, A.1
-
79
-
-
0027137598
-
Immune-stimulating complexes as adjuvants for local and systemic immunity after oral immunization with protein antigens
-
Mowat, A.M., Maloy, K.J. & Donachie, A.M. (1993), Immune-stimulating complexes as adjuvants for local and systemic immunity after oral immunization with protein antigens. Immunology, 80, 527-534.
-
(1993)
Immunology
, vol.80
, pp. 527-534
-
-
Mowat, A.M.1
Maloy, K.J.2
Donachie, A.M.3
-
80
-
-
0025338731
-
Cholera toxin discriminates between T helper 1 and 2 cells in T cell receptor-mediated activation: Role of cAMP in T cell proliferation
-
Munoz, E., Zubiaga, A.M., Merrow, M., Sauter, N.P. & Huber, B. (1990), Cholera toxin discriminates between T helper 1 and 2 cells in T cell receptor-mediated activation: role of cAMP in T cell proliferation. J. Exp. Med., 172, 95-103.
-
(1990)
J. Exp. Med.
, vol.172
, pp. 95-103
-
-
Munoz, E.1
Zubiaga, A.M.2
Merrow, M.3
Sauter, N.P.4
Huber, B.5
-
81
-
-
0030030530
-
Potent immunogenicity of the B subunits of Escherichia coli heat-labile enterotoxin: Receptor binding is essential and induces differential modulation of lymphocyte subsets
-
Nashar, T.O., Webb, H.M., Eaglestone, S., Williams, N.A. & Hirst, T.R. (1996a), Potent immunogenicity of the B subunits of Escherichia coli heat-labile enterotoxin: receptor binding is essential and induces differential modulation of lymphocyte subsets. Immunology, 93, 226-230.
-
(1996)
Immunology
, vol.93
, pp. 226-230
-
-
Nashar, T.O.1
Webb, H.M.2
Eaglestone, S.3
Williams, N.A.4
Hirst, T.R.5
-
83
-
-
0025585470
-
Cholera toxin as a mucosal adjuvant: III. Antibody responses to nontarget dietary antigens are not increased
-
Nedrud, J.G. & Sigmund, N. (1990), Cholera toxin as a mucosal adjuvant: III. Antibody responses to nontarget dietary antigens are not increased. Reg. Immunol., 3, 217-222.
-
(1990)
Reg. Immunol.
, vol.3
, pp. 217-222
-
-
Nedrud, J.G.1
Sigmund, N.2
-
84
-
-
0029874545
-
+ Th2 cells producing IL-6 and IL-10 are associated with mucosal immunoglobulin A responses
-
+ Th2 cells producing IL-6 and IL-10 are associated with mucosal immunoglobulin A responses. Infect. Immun., 64, 1516-1525.
-
(1996)
Infect. Immun.
, vol.64
, pp. 1516-1525
-
-
Okahashi, N.1
Yamamoto, M.2
Vancott, J.L.3
Chatfield, S.N.4
Roberts, M.5
Bluethmann, H.6
Hiroi, T.7
Kiyono, H.8
McGhee, J.R.9
-
85
-
-
0031572209
-
Cholera toxin stimulates human B-cell DR antigen biosynthesis at the level of translation
-
Papadimitriou, E., Mintzas, A., Skoutari, M., Dimitracopoulos, G. & Anastassiou, E.D. (1997), Cholera toxin stimulates human B-cell DR antigen biosynthesis at the level of translation. Cell. Immunol., 180, 176-184.
-
(1997)
Cell. Immunol.
, vol.180
, pp. 176-184
-
-
Papadimitriou, E.1
Mintzas, A.2
Skoutari, M.3
Dimitracopoulos, G.4
Anastassiou, E.D.5
-
86
-
-
0002448020
-
Structure and evolutionary aspects of ADP-ribosylating toxins
-
(J.E. Alouf and J.H. Freer) Academic Press, London
-
Rappuoli, R. & Pizza, M. (1991), Structure and evolutionary aspects of ADP-ribosylating toxins, in "Sourcebook of bacterial protein toxins" (J.E. Alouf and J.H. Freer) (pp. 1-21). Academic Press, London.
-
(1991)
Sourcebook of Bacterial Protein Toxins
, pp. 1-21
-
-
Rappuoli, R.1
Pizza, M.2
-
87
-
-
0028055141
-
Mice transgenic for a soluble form of murine CTLA4 show enhanced expansion of antigen-specific CD4+ T-cells and defective antibody production in vivo
-
Ronchese, F., Hausmann, B., Hubele, S. & Lane, P. (1994), Mice transgenic for a soluble form of murine CTLA4 show enhanced expansion of antigen-specific CD4+ T-cells and defective antibody production in vivo. J. Exp. Med., 179, 809-816.
-
(1994)
J. Exp. Med.
, vol.179
, pp. 809-816
-
-
Ronchese, F.1
Hausmann, B.2
Hubele, S.3
Lane, P.4
-
88
-
-
0025993760
-
Distribution, persistence and recall of serum and salivary antibody responses to peroral immunization with protein antigen I/II of Streptococcus mutans coupled to the cholera toxin B subunit
-
Russel, M.W. & Wu, H.-Y. (1991), Distribution, persistence and recall of serum and salivary antibody responses to peroral immunization with protein antigen I/II of Streptococcus mutans coupled to the cholera toxin B subunit. Infect. Immun., 59, 4061-4070.
-
(1991)
Infect. Immun.
, vol.59
, pp. 4061-4070
-
-
Russel, M.W.1
Wu, H.-Y.2
-
89
-
-
0030608979
-
h cells in mesenteric lymph nodes after oral immunization with protein antigen and cholera toxin
-
h cells in mesenteric lymph nodes after oral immunization with protein antigen and cholera toxin. Int. Immunol., 9, 1555-1562.
-
(1997)
Int. Immunol.
, vol.9
, pp. 1555-1562
-
-
Schaffeler, M.P.1
Brokenshire, J.S.2
Snider, D.P.3
-
90
-
-
0027174854
-
Refined structure of Escherichia coli heat-labile enterotoxin, a close relative of cholera toxin
-
Sixma, T.K., Kalk, K.H., van Zanten, B.A., Dauter, Z., Kingma, J., Witholt, B. & Hol, W.G. (1993), Refined structure of Escherichia coli heat-labile enterotoxin, a close relative of cholera toxin. J. Mol. Biol., 230, 890.
-
(1993)
J. Mol. Biol.
, vol.230
, pp. 890
-
-
Sixma, T.K.1
Kalk, K.H.2
Van Zanten, B.A.3
Dauter, Z.4
Kingma, J.5
Witholt, B.6
Hol, W.G.7
-
91
-
-
0031946347
-
Preservation of mucosal and systemic adjuvant properties of iscoms in the absence of functional interleukin 4 or interferon gamma
-
in press
-
Smith, E., Donachie, A.M., McLaren, F.H. & Mowat, A. (1998), Preservation of mucosal and systemic adjuvant properties of Iscoms in the absence of functional interleukin 4 or interferon gamma. Immunology (in press).
-
(1998)
Immunology
-
-
Smith, E.1
Donachie, A.M.2
McLaren, F.H.3
Mowat, A.4
-
92
-
-
0028228375
-
Production of IgE antibody and allergic sensitization of intestinal and peripheral tissues after oral immunization with protein ag and cholera toxin
-
Snider, D.P., Marshall, J.S., Perdue, M.H. & Liang, H. (1994), Production of IgE antibody and allergic sensitization of intestinal and peripheral tissues after oral immunization with protein ag and cholera toxin. J. Immunol., 153, 647-657.
-
(1994)
J. Immunol.
, vol.153
, pp. 647-657
-
-
Snider, D.P.1
Marshall, J.S.2
Perdue, M.H.3
Liang, H.4
-
93
-
-
0026458260
-
Structure and function of cholera toxin and the related Escherichia coli heat-labile enterotoxin
-
Spangler, B.D. (1992), Structure and function of cholera toxin and the related Escherichia coli heat-labile enterotoxin. Microbiol. Rev., 56, 622-630.
-
(1992)
Microbiol. Rev.
, vol.56
, pp. 622-630
-
-
Spangler, B.D.1
-
94
-
-
0028181231
-
IL-4 treatment of small splenic B cells induces costimulatory molecules B7-1 and B7-2
-
Stack, R.M., Lenschow, D.J., Gray, G.S., Bluestone, J.A. & Fitch, F.W. (1994), IL-4 treatment of small splenic B cells induces costimulatory molecules B7-1 and B7-2. J. Immunol., 152, 5723-5730.
-
(1994)
J. Immunol.
, vol.152
, pp. 5723-5730
-
-
Stack, R.M.1
Lenschow, D.J.2
Gray, G.S.3
Bluestone, J.A.4
Fitch, F.W.5
-
95
-
-
0011444474
-
Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constant region genes
-
Stavnezer, J., Radcliff, G., Lin, Y.-C., Nietupski, J., Berggren, L., Sitia, R. & Severinson, E. (1988), Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constant region genes. Proc. Natl. Acad. Sci. USA, 85, 7704-7708.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 7704-7708
-
-
Stavnezer, J.1
Radcliff, G.2
Lin, Y.-C.3
Nietupski, J.4
Berggren, L.5
Sitia, R.6
Severinson, E.7
-
96
-
-
0029862687
-
B cells solicit their own help from T cells
-
Stockinger, B., Zal, T., Zal, A. & Gray, D. (1996), B cells solicit their own help from T cells. J. Exp. Med., 183, 891-901.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 891-901
-
-
Stockinger, B.1
Zal, T.2
Zal, A.3
Gray, D.4
-
97
-
-
0002265224
-
Regulation of IgA B cell development
-
(P.L. Ogra, W. Strober, J. Mestecky, J.R. McGhee, M.E. Lamm, and J. Bienenstock) Academic Press, Inc., San Diego
-
Strober, W. & Ehrhardt, R.O. (1994), Regulation of IgA B cell development, in "Handbook of Mucosal Immunology" (P.L. Ogra, W. Strober, J. Mestecky, J.R. McGhee, M.E. Lamm, and J. Bienenstock) (pp. 159-176). Academic Press, Inc., San Diego.
-
(1994)
Handbook of Mucosal Immunology
, pp. 159-176
-
-
Strober, W.1
Ehrhardt, R.O.2
-
98
-
-
0028007467
-
Cholera toxin B subunit: An efficient transmucosal carrier-delivery system for induction of peripheral immunological tolerance
-
Sun, J.-B., Holmgren, J. & Czerkinsky, C. (1994), Cholera toxin B subunit: an efficient transmucosal carrier-delivery system for induction of peripheral immunological tolerance. Proc. Natl. Acad. Sci. USA, 91, 10795-10799.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 10795-10799
-
-
Sun, J.-B.1
Holmgren, J.2
Czerkinsky, C.3
-
99
-
-
0029935568
-
Acceleration of influenza virus clearance by Th1 cells in the nasal site of mice immunized intranasally with adjuvant-combined recombinant nucleoprotein
-
Tamura, S., Miyata, K., Matsuo, K., Asanuma, H., Takahashi, H., Nakajima, K., Suzuki, Y., Aizawa, C. & Kurata, T. (1996), Acceleration of influenza virus clearance by Th1 cells in the nasal site of mice immunized intranasally with adjuvant-combined recombinant nucleoprotein. J. Immunol., 156, 3892-3900.
-
(1996)
J. Immunol.
, vol.156
, pp. 3892-3900
-
-
Tamura, S.1
Miyata, K.2
Matsuo, K.3
Asanuma, H.4
Takahashi, H.5
Nakajima, K.6
Suzuki, Y.7
Aizawa, C.8
Kurata, T.9
-
100
-
-
0023767597
-
Protection against influenza virus infection by vaccine inoculated intranasally with cholera toxin B subunit
-
Tamura, S., Samegai, Y., Kurata, H., Nagamine, T., Aizawa, C. & Kurata, T. (1988), Protection against influenza virus infection by vaccine inoculated intranasally with cholera toxin B subunit. Vaccine, 6, 409-413.
-
(1988)
Vaccine
, vol.6
, pp. 409-413
-
-
Tamura, S.1
Samegai, Y.2
Kurata, H.3
Nagamine, T.4
Aizawa, C.5
Kurata, T.6
-
101
-
-
19144364760
-
Mechanisms for mucosal immunogenicity and adjuvancy of Escherichia coli labile enterotoxin
-
Takahashi, I., Marinaro, M., Kiyono, H., Jackson, R.J., Nakagawa, I., Fujihashi, K., Hamada, S., Clements, J.D., Bost, K.L. & McGhee, J.R. (1996), Mechanisms for mucosal immunogenicity and adjuvancy of Escherichia coli labile enterotoxin. J. Infect. Dis., 173, 627-635.
-
(1996)
J. Infect. Dis.
, vol.173
, pp. 627-635
-
-
Takahashi, I.1
Marinaro, M.2
Kiyono, H.3
Jackson, R.J.4
Nakagawa, I.5
Fujihashi, K.6
Hamada, S.7
Clements, J.D.8
Bost, K.L.9
McGhee, J.R.10
-
102
-
-
0030695356
-
Strong mucosal adjuvanticity of cholera toxin within lipid particles of a new multiple emulsion delivery system for oral immunization
-
Tomasi, M., Dertzbaugh, M.T., Hearn, T., Hunter, R.L. & Elson, C.O. (1997), Strong mucosal adjuvanticity of cholera toxin within lipid particles of a new multiple emulsion delivery system for oral immunization. Eur. J. Immunol., 27, 2720-2725.
-
(1997)
Eur. J. Immunol.
, vol.27
, pp. 2720-2725
-
-
Tomasi, M.1
Dertzbaugh, M.T.2
Hearn, T.3
Hunter, R.L.4
Elson, C.O.5
-
103
-
-
0343978503
-
Regulation of mucosal and systemic antibody responses by T helper cell subsets, macrophages, and derived cytokines following oral immunization with live recombinant Salmonella
-
VanCott, J.L., Staats, H.F., Pascual, D.W., Roberts, M., Chatfield, S.N., Yamamoto, M., Coste, M., Carter, P.B., Kiyono, H. & McGhee, J.R. (1996), Regulation of mucosal and systemic antibody responses by T helper cell subsets, macrophages, and derived cytokines following oral immunization with live recombinant Salmonella. J. Immunol., 156, 1504-1514.
-
(1996)
J. Immunol.
, vol.156
, pp. 1504-1514
-
-
Vancott, J.L.1
Staats, H.F.2
Pascual, D.W.3
Roberts, M.4
Chatfield, S.N.5
Yamamoto, M.6
Coste, M.7
Carter, P.B.8
Kiyono, H.9
McGhee, J.R.10
-
104
-
-
0025971221
-
Manipulation of intestinal immune responses against ovalbumin by cholera toxin and its B-subunit in mice
-
Van der Heijden, P.J., Bianchi, A.T., Dol, M., Pals, J.W., Stok, W. & Bokhout, B.A. (1991), Manipulation of intestinal immune responses against ovalbumin by cholera toxin and its B-subunit in mice. Immunology, 72, 89-93.
-
(1991)
Immunology
, vol.72
, pp. 89-93
-
-
Van Der Heijden, P.J.1
Bianchi, A.T.2
Dol, M.3
Pals, J.W.4
Stok, W.5
Bokhout, B.A.6
-
105
-
-
0026510246
-
Cholera toxin adjuvant promotes longterm immunological memory in the gut mucosa to unrelated immunogens after oral immunization
-
Vajdy, M. & Lycke, N. (1992), Cholera toxin adjuvant promotes longterm immunological memory in the gut mucosa to unrelated immunogens after oral immunization. Immunology, 75, 488-492.
-
(1992)
Immunology
, vol.75
, pp. 488-492
-
-
Vajdy, M.1
Lycke, N.2
-
106
-
-
0027440322
-
Stimulation of antigen-specific T and B-cell memory in local as well as systemic lymphoid tissues following oral immunization with cholera toxin adjuvant
-
Vajdy, M. & Lycke, N. (1993), Stimulation of antigen-specific T and B-cell memory in local as well as systemic lymphoid tissues following oral immunization with cholera toxin adjuvant. Immunology, 80, 197-203.
-
(1993)
Immunology
, vol.80
, pp. 197-203
-
-
Vajdy, M.1
Lycke, N.2
-
107
-
-
0028886993
-
Mucosal memory B cells retain the ability to produce IgM antibodies even 2 years after oral immunizations
-
in press
-
Vajdy, M. & Lycke, N. (1995), Mucosal memory B cells retain the ability to produce IgM antibodies even 2 years after oral immunizations. Immunology (in press).
-
(1995)
Immunology
-
-
Vajdy, M.1
Lycke, N.2
-
108
-
-
0028906467
-
Impaired mucosal immune responses in IL-4 targeted mice
-
Vajdy, M., Kosco-Vilbois, M., Kopf, M., Köhler, G. & Lycke, N. (1995), Impaired mucosal immune responses in IL-4 targeted mice. J. Exp. Med., 181, 41-53.
-
(1995)
J. Exp. Med.
, vol.181
, pp. 41-53
-
-
Vajdy, M.1
Kosco-Vilbois, M.2
Kopf, M.3
Köhler, G.4
Lycke, N.5
-
109
-
-
0026048323
-
The in vitro production of cytokines by mucosal lymphocytes immunized by oral administration of keyhole limpet hemocyanin using cholera toxin as an adjuvant
-
Wilson, A.D., Bailey, M., Williams, N.A. & Stokes, C.R. (1991), The in vitro production of cytokines by mucosal lymphocytes immunized by oral administration of keyhole limpet hemocyanin using cholera toxin as an adjuvant. Eur. J. Immunol., 21, 2333-2340.
-
(1991)
Eur. J. Immunol.
, vol.21
, pp. 2333-2340
-
-
Wilson, A.D.1
Bailey, M.2
Williams, N.A.3
Stokes, C.R.4
-
110
-
-
0023567029
-
Inhibition of murine lymphocyte proliferation by the B subunit of cholera toxin
-
Woogen, S.D., Ealding, W. & Elson, C.O. (1987), Inhibition of murine lymphocyte proliferation by the B subunit of cholera toxin. J. Immunol., 139, 3764-3770.
-
(1987)
J. Immunol.
, vol.139
, pp. 3764-3770
-
-
Woogen, S.D.1
Ealding, W.2
Elson, C.O.3
-
111
-
-
0027396382
-
Induction of mucosal immunity by intranasal application of a streptococcal surface protein antigen with the cholera toxin B subunit
-
Wu, H.-Y. & Russell, M.W. (1993), Induction of mucosal immunity by intranasal application of a streptococcal surface protein antigen with the cholera toxin B subunit. Infect. Immun., 61, 314-320.
-
(1993)
Infect. Immun.
, vol.61
, pp. 314-320
-
-
Wu, H.-Y.1
Russell, M.W.2
-
112
-
-
0007205169
-
A nontoxic mutant of cholera toxin elicits Th2-type responses for enhanced mucosal immunity
-
Yamamoto, S., Kiyono, H., Yamamoto, M., Imaoka, K., Yamamoto, M., Fujihashi, K., Van Ginkel, F.W., Noda, M., Takeda, Y. & McGhee, J.R. (1997b), A nontoxic mutant of cholera toxin elicits Th2-type responses for enhanced mucosal immunity. Proc. Natl. Acad. Sci. USA, 94, 5267-5272.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 5267-5272
-
-
Yamamoto, S.1
Kiyono, H.2
Yamamoto, M.3
Imaoka, K.4
Yamamoto, M.5
Fujihashi, K.6
Van Ginkel, F.W.7
Noda, M.8
Takeda, Y.9
McGhee, J.R.10
-
113
-
-
0030902280
-
Mutants in the ADP-ribosyltransferase cleft of cholera toxin lack diarreheagenicity but retain adjuvanticity
-
Yamamoto, S., Takeda, Y., Yamamoto, M., Kurazono, H., Imaoka, K., Yamamoto, M., Fujihashi, K., Noda, M., Kiyono, H. & McGhee, J.R. (1997a), Mutants in the ADP-ribosyltransferase cleft of cholera toxin lack diarreheagenicity but retain adjuvanticity. J. Exp. Med., 7, 1203-1210.
-
(1997)
J. Exp. Med.
, vol.7
, pp. 1203-1210
-
-
Yamamoto, S.1
Takeda, Y.2
Yamamoto, M.3
Kurazono, H.4
Imaoka, K.5
Yamamoto, M.6
Fujihashi, K.7
Noda, M.8
Kiyono, H.9
McGhee, J.R.10
-
114
-
-
0027183310
-
Helper T cell subsets for immunoglobulin A responses: Oral immunization with tetanus toxoid and cholera toxin as adjuvant selectively induces Th2 cells in mucosa-associated tissues
-
Xu-Amano, J., Kiyono, H., Jackson, R.J., Staats, H.F., Fujihashi, K., Burrows, P.D., Elson, CO., Pillai, S. & McGhee, J.R. (1993), Helper T cell subsets for immunoglobulin A responses: oral immunization with tetanus toxoid and cholera toxin as adjuvant selectively induces Th2 cells in mucosa-associated tissues. J. Exp. Med., 178, 1309-1320.
-
(1993)
J. Exp. Med.
, vol.178
, pp. 1309-1320
-
-
Xu-Amano, J.1
Kiyono, H.2
Jackson, R.J.3
Staats, H.F.4
Fujihashi, K.5
Burrows, P.D.6
Elson, C.O.7
Pillai, S.8
McGhee, J.R.9
|