Injury enhances TLR2 function and antimicrobial peptide expression through a vitamin D-dependent mechanism

Journal of Clinical Investigation

Volumn 117, Issue 3, 2007, Pages 803-811

  Schauber, Jürgen ^a,b   Dorschner, Robert A ^a,b   Coda, Alvin B ^a,b   Büchau, Amanda S ^a,b   Liu, Philip T ^c   Kiken, David ^a,b   Helfrich, Yolanda R ^d   Kang, Sewon ^d   Elalieh, Hashem Z ^e   Steinmeyer, Andreas ^f   Zügel, Ulrich ^f   Bikle, Daniel D ^e   Modlin, Robert L ^c   Gallo, Richard L ^a,b,g  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f BAYER PHARMA AG   (Germany)

^g Mail Code 151 ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIDIOL 1 MONOOXYGENASE; CATHELICIDIN; CD14 ANTIGEN; COLECALCIFEROL; POLYPEPTIDE ANTIBIOTIC AGENT; TOLL LIKE RECEPTOR 2; TRANSFORMING GROWTH FACTOR BETA1; VITAMIN D RECEPTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; DRUG EFFECT; DRUG MECHANISM; GENE CONTROL; GENE EXPRESSION; GENETIC ANALYSIS; GENETIC CODE; HUMAN; HUMAN CELL; HUMAN TISSUE; INFECTION CONTROL; INNATE IMMUNITY; KERATINOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SKIN BIOPSY; SKIN INJURY; VITAMIN D METABOLISM; WOUND HEALING; WOUND INFECTION;

25-HYDROXYVITAMIN D3 1-ALPHA-HYDROXYLASE; ANIMALS; ANTIGENS, CD14; ANTIMICROBIAL CATIONIC PEPTIDES; CALCITRIOL; EPIDERMIS; GENE EXPRESSION; HUMANS; IMMUNITY, NATURAL; KERATINOCYTES; MICE; MICE, MUTANT STRAINS; RECEPTORS, CALCITRIOL; TOLL-LIKE RECEPTOR 2; TRANSFORMING GROWTH FACTOR BETA1; VITAMIN D; WOUND HEALING;

EID: 33847220444     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI30142     Document Type: Article

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