Suppressive effect of simvastatin on interferon-β-induced expression of CC chemokine ligand 5 in microglia

Neuroscience Letters

Volumn 407, Issue 3, 2006, Pages 205-210

  Nakamichi, Kazuo ^a   Saiki, Megumi ^a,b   Kitani, Hiroshi ^c   Kuboyama, Yuki ^a,b   Morimoto, Kinjiro ^a   Takayama Ito, Mutsuyo ^a   Kurane, Ichiro ^a  

^a NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^b NIHON UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE OF AGROBIOLOGICAL SCIENCES   (Japan)

Author keywords

Chemokine; Cytokine; Microglia; Signal transduction; Statin

Indexed keywords

BETA INTERFERON; CHEMOATTRACTANT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; JANUS KINASE; RANTES; SIMVASTATIN; STAT PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; DOWN REGULATION; DRUG INHIBITION; HUMAN; HUMAN CELL; INFLAMMATORY CELL; MICROGLIA; MOUSE; NERVE CELL; NERVE CELL STIMULATION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN SECRETION; SIGNAL TRANSDUCTION;

ANIMALS; ANIMALS, NEWBORN; CELL LINE; CHEMOKINE CCL5; CHEMOKINES, CC; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; INTERFERON TYPE I, RECOMBINANT; JANUS KINASE 1; MICE; MICE, INBRED C57BL; MICROGLIA; PHOSPHORYLATION; SIGNAL TRANSDUCTION; SIMVASTATIN; STAT1 TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33748745943     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2006.08.044     Document Type: Article

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