-
2
-
-
33847279025
-
Pathogenesis and therapy of psoriasis
-
Lowes, M.A., Bowcock, A.M., and Krueger, J.G. 2007. Pathogenesis and therapy of psoriasis. Nature. 445:866-873.
-
(2007)
Nature
, vol.445
, pp. 866-873
-
-
Lowes, M.A.1
Bowcock, A.M.2
Krueger, J.G.3
-
3
-
-
25444435193
-
Getting under the skin: The immunogenetics of psoriasis
-
Bowcock, A.M., and Krueger, J.G. 2005. Getting under the skin: the immunogenetics of psoriasis. Nat. Rev. Immunol. 5:699-711.
-
(2005)
Nat. Rev. Immunol
, vol.5
, pp. 699-711
-
-
Bowcock, A.M.1
Krueger, J.G.2
-
4
-
-
3042845754
-
Recent insights into the immunopathogenesis of psoriasis provide new therapeutic opportunities
-
Nickoloff, B.J., and Nestle, F.O. 2004. Recent insights into the immunopathogenesis of psoriasis provide new therapeutic opportunities. J. Clin. Invest. 113:1664-1675.
-
(2004)
J. Clin. Invest
, vol.113
, pp. 1664-1675
-
-
Nickoloff, B.J.1
Nestle, F.O.2
-
5
-
-
10744221697
-
A randomized trial of etanercept as monotherapy for psoriasis
-
Gottlieb, A.B., et al. 2003. A randomized trial of etanercept as monotherapy for psoriasis. Arch. Dermatol. 139:1627-1632.
-
(2003)
Arch. Dermatol
, vol.139
, pp. 1627-1632
-
-
Gottlieb, A.B.1
-
6
-
-
21644481166
-
A global phase III randomized controlled trial of etanercept in psoriasis: Safety, efficacy, and effect of dose reduction
-
Papp, K.A., et al. 2005. A global phase III randomized controlled trial of etanercept in psoriasis: safety, efficacy, and effect of dose reduction. Br. J. Dermatol. 152:1304-1312.
-
(2005)
Br. J. Dermatol
, vol.152
, pp. 1304-1312
-
-
Papp, K.A.1
-
7
-
-
0035832515
-
Efficacy and safety of infliximab monotherapy for plaque-type psoriasis: A randomised trial
-
Chaudhari, U., et al. 2001. Efficacy and safety of infliximab monotherapy for plaque-type psoriasis: a randomised trial. Lancet. 357:1842-1847.
-
(2001)
Lancet
, vol.357
, pp. 1842-1847
-
-
Chaudhari, U.1
-
8
-
-
26644433889
-
Infliximab induction and maintenance therapy for moderate-to-severe psoriasis: A phase III, multicentre, double-blind trial
-
Reich, K., et al. 2005. Infliximab induction and maintenance therapy for moderate-to-severe psoriasis: a phase III, multicentre, double-blind trial. Lancet. 366:1367-1374.
-
(2005)
Lancet
, vol.366
, pp. 1367-1374
-
-
Reich, K.1
-
9
-
-
0037434789
-
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inf lammation of the brain
-
Cua, D.J., et al. 2003. Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inf lammation of the brain. Nature. 421:744-748.
-
(2003)
Nature
, vol.421
, pp. 744-748
-
-
Cua, D.J.1
-
10
-
-
0346962972
-
Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation
-
Murphy, C.A., et al. 2003. Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation. J. Exp. Med. 198:1951-1957.
-
(2003)
J. Exp. Med
, vol.198
, pp. 1951-1957
-
-
Murphy, C.A.1
-
11
-
-
13244283212
-
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
-
Langrish, C.L., et al. 2005. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J. Exp. Med. 201:233-240.
-
(2005)
J. Exp. Med
, vol.201
, pp. 233-240
-
-
Langrish, C.L.1
-
12
-
-
42149161160
-
T-helper 17 cells in psoriatic plaques and additional genetic links between IL-23 and psoriasis
-
Blauvelt, A. 2008. T-helper 17 cells in psoriatic plaques and additional genetic links between IL-23 and psoriasis. J. Invest. Dermatol. 128:1064-1067.
-
(2008)
J. Invest. Dermatol
, vol.128
, pp. 1064-1067
-
-
Blauvelt, A.1
-
13
-
-
47249125726
-
Chronically inflamed human tissues are infiltrated by highly differentiated Th17 lymphocytes
-
Pene, J., et al. 2008. Chronically inflamed human tissues are infiltrated by highly differentiated Th17 lymphocytes. J. Immunol. 180:7423-7430.
-
(2008)
J. Immunol
, vol.180
, pp. 7423-7430
-
-
Pene, J.1
-
14
-
-
35348960243
-
Th17: The third member of the effector T cell trilogy
-
Bettelli, E., Korn, T., and Kuchroo, V.K. 2007. Th17: the third member of the effector T cell trilogy. Curr. Opin. Immunol. 19:652-657.
-
(2007)
Curr. Opin. Immunol
, vol.19
, pp. 652-657
-
-
Bettelli, E.1
Korn, T.2
Kuchroo, V.K.3
-
15
-
-
41549135632
-
The biological functions of T helper 17 cell effector cytokines in inflammation
-
Ouyang, W., Kolls, J.K., and Zheng, Y. 2008. The biological functions of T helper 17 cell effector cytokines in inflammation. Immunity. 28:454-467.
-
(2008)
Immunity
, vol.28
, pp. 454-467
-
-
Ouyang, W.1
Kolls, J.K.2
Zheng, Y.3
-
16
-
-
42149087160
-
Psoriasis Vulgaris Lesions Contain Discrete Populations of Th1 and Th17 T Cells
-
Lowes, M.A., et al. 2008. Psoriasis Vulgaris Lesions Contain Discrete Populations of Th1 and Th17 T Cells. J. Invest. Dermatol. 128:1207-1211.
-
(2008)
J. Invest. Dermatol
, vol.128
, pp. 1207-1211
-
-
Lowes, M.A.1
-
17
-
-
42149156689
-
Blockade of CD11a by efalizumab in psoriasis patients induces a unique state of T-cell hyporesponsiveness
-
Guttman-Yassky, E., et al. 2008. Blockade of CD11a by efalizumab in psoriasis patients induces a unique state of T-cell hyporesponsiveness. J. Invest. Dermatol. 128:1182-1191.
-
(2008)
J. Invest. Dermatol
, vol.128
, pp. 1182-1191
-
-
Guttman-Yassky, E.1
-
18
-
-
34548661488
-
Interleukin-17 in inflammatory skin disorders
-
van Beelen, A.J., Teunissen, M.B., Kapsenberg, M.L., and de Jong, E.C. 2007. Interleukin-17 in inflammatory skin disorders. Curr. Opin. Allergy Clin. Immunol. 7:374-381.
-
(2007)
Curr. Opin. Allergy Clin. Immunol
, vol.7
, pp. 374-381
-
-
van Beelen, A.J.1
Teunissen, M.B.2
Kapsenberg, M.L.3
de Jong, E.C.4
-
19
-
-
37349131221
-
Pathophysiology of psoriasis: Recent advances on IL-23 and Th17 cytokines
-
Fitch, E., Harper, E., Skorcheva, I., Kurtz, S.E., and Blauvelt, A. 2007. Pathophysiology of psoriasis: recent advances on IL-23 and Th17 cytokines. Curr. Rheumatol. Rep. 9:461-467.
-
(2007)
Curr. Rheumatol. Rep
, vol.9
, pp. 461-467
-
-
Fitch, E.1
Harper, E.2
Skorcheva, I.3
Kurtz, S.E.4
Blauvelt, A.5
-
20
-
-
0347285359
-
Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris
-
Lee, E., et al. 2004. Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris. J. Exp. Med. 199:125-130.
-
(2004)
J. Exp. Med
, vol.199
, pp. 125-130
-
-
Lee, E.1
-
21
-
-
37549011317
-
Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses
-
Zaba, L.C., et al. 2007. Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses. J. Exp. Med. 204:3183-3194.
-
(2007)
J. Exp. Med
, vol.204
, pp. 3183-3194
-
-
Zaba, L.C.1
-
22
-
-
31144441631
-
In vitro and in situ expression of IL-23 by keratinocytes in healthy skin and psoriasis lesions: Enhanced expression in psoriatic skin
-
Piskin, G., Sylva-Steenland, R.M., Bos, J.D., and Teunissen, M.B. 2006. In vitro and in situ expression of IL-23 by keratinocytes in healthy skin and psoriasis lesions: enhanced expression in psoriatic skin. J. Immunol. 176:1908-1915.
-
(2006)
J. Immunol
, vol.176
, pp. 1908-1915
-
-
Piskin, G.1
Sylva-Steenland, R.M.2
Bos, J.D.3
Teunissen, M.B.4
-
23
-
-
34548133583
-
Development, cytokine profile and function of human interleukin 17-producing helper T cells
-
Wilson, N.J., et al. 2007. Development, cytokine profile and function of human interleukin 17-producing helper T cells. Nat. Immunol. 8:950-957.
-
(2007)
Nat. Immunol
, vol.8
, pp. 950-957
-
-
Wilson, N.J.1
-
24
-
-
0033638507
-
Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
-
Oppmann, B., et al. 2000. Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity. 13:715-725.
-
(2000)
Immunity
, vol.13
, pp. 715-725
-
-
Oppmann, B.1
-
25
-
-
0037449737
-
Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17
-
Aggarwal, S., Ghilardi, N., Xie, M.H., de Sauvage, F.J., and Gurney, A.L. 2003. Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17. J. Biol. Chem. 278:1910-1914.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 1910-1914
-
-
Aggarwal, S.1
Ghilardi, N.2
Xie, M.H.3
de Sauvage, F.J.4
Gurney, A.L.5
-
26
-
-
44049104564
-
The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat
-
Manel, N., Unutmaz, D., and Littman, D.R. 2008. The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat. Nat. Immunol. 9:641-649.
-
(2008)
Nat. Immunol
, vol.9
, pp. 641-649
-
-
Manel, N.1
Unutmaz, D.2
Littman, D.R.3
-
27
-
-
44049102724
-
A critical function for transforming growth factor-beta, interleukin 23 and proinflammatory cytokines in driving and modulating human T(H)-17 responses
-
Volpe, E., et al. 2008. A critical function for transforming growth factor-beta, interleukin 23 and proinflammatory cytokines in driving and modulating human T(H)-17 responses. Nat. Immunol. 9:650-657.
-
(2008)
Nat. Immunol
, vol.9
, pp. 650-657
-
-
Volpe, E.1
-
28
-
-
60749107176
-
The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo
-
McGeachy, M.J., et al. 2009. The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo. Nat. Immunol. 10:314-324.
-
(2009)
Nat. Immunol
, vol.10
, pp. 314-324
-
-
McGeachy, M.J.1
-
29
-
-
34547774225
-
Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis
-
Capon, F., et al. 2007. Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis. Hum. Genet. 122:201-206.
-
(2007)
Hum. Genet
, vol.122
, pp. 201-206
-
-
Capon, F.1
-
30
-
-
33846608131
-
A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes
-
Cargill, M., et al. 2007. A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes. Am. J. Hum. Genet. 80:273-290.
-
(2007)
Am. J. Hum. Genet
, vol.80
, pp. 273-290
-
-
Cargill, M.1
-
31
-
-
42149140747
-
Polymorphisms of the IL12B and IL23R genes are associated with psoriasis
-
Nair, R.P., et al. 2008. Polymorphisms of the IL12B and IL23R genes are associated with psoriasis. J. Invest. Dermatol. 128:1653-1661.
-
(2008)
J. Invest. Dermatol
, vol.128
, pp. 1653-1661
-
-
Nair, R.P.1
-
32
-
-
59149106117
-
Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways
-
Nair, R.P., et al. 2009. Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways. Nat. Genet. 41:199-204.
-
(2009)
Nat. Genet
, vol.41
, pp. 199-204
-
-
Nair, R.P.1
-
33
-
-
33846889522
-
A human interleukin-12/23 monoclonal antibody for the treatment of psoriasis
-
Krueger, G.G., et al. 2007. A human interleukin-12/23 monoclonal antibody for the treatment of psoriasis. N. Engl. J. Med. 356:580-592.
-
(2007)
N. Engl. J. Med
, vol.356
, pp. 580-592
-
-
Krueger, G.G.1
-
34
-
-
43449111187
-
Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis:76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1)
-
Leonardi, C.L., et al. 2008. Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis:76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1). Lancet. 371:1665-1674.
-
(2008)
Lancet
, vol.371
, pp. 1665-1674
-
-
Leonardi, C.L.1
-
35
-
-
43449139402
-
Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis:52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2)
-
Papp, K.A., et al. 2008. Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis:52-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 2). Lancet. 371:1675-1684.
-
(2008)
Lancet
, vol.371
, pp. 1675-1684
-
-
Papp, K.A.1
-
36
-
-
0038189842
-
IL-23 production by cosecretion of endogenous p19 and transgenic p40 in keratin 14/p40 transgenic mice: Evidence for enhanced cutaneous immunity
-
Kopp, T., et al. 2003. IL-23 production by cosecretion of endogenous p19 and transgenic p40 in keratin 14/p40 transgenic mice: evidence for enhanced cutaneous immunity. J. Immunol. 170:5438-5444.
-
(2003)
J. Immunol
, vol.170
, pp. 5438-5444
-
-
Kopp, T.1
-
37
-
-
33751546237
-
IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis
-
Chan, J.R., et al. 2006. IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis. J. Exp. Med. 203:2577-2587.
-
(2006)
J. Exp. Med
, vol.203
, pp. 2577-2587
-
-
Chan, J.R.1
-
38
-
-
33846906224
-
Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis
-
Zheng, Y., et al. 2007. Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis. Nature. 445:648-651.
-
(2007)
Nature
, vol.445
, pp. 648-651
-
-
Zheng, Y.1
-
39
-
-
38849187386
-
IL-22 is required for Th17 cell-mediated pathology in a mouse model of psoriasislike skin inflammation
-
Ma, H.L., et al. 2008. IL-22 is required for Th17 cell-mediated pathology in a mouse model of psoriasislike skin inflammation. J. Clin. Invest. 118:597-607.
-
(2008)
J. Clin. Invest
, vol.118
, pp. 597-607
-
-
Ma, H.L.1
-
40
-
-
33846940253
-
The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis
-
Sa, S.M., et al. 2007. The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis. J. Immunol. 178:2229-2240.
-
(2007)
J. Immunol
, vol.178
, pp. 2229-2240
-
-
Sa, S.M.1
-
41
-
-
4143095716
-
IL-22 increases the innate immunity of tissues
-
Wolk, K., et al. 2004. IL-22 increases the innate immunity of tissues. Immunity. 21:241-254.
-
(2004)
Immunity
, vol.21
, pp. 241-254
-
-
Wolk, K.1
-
42
-
-
33646552450
-
IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: A potential role in psoriasis
-
Wolk, K., et al. 2006. IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis. Eur. J. Immunol. 36:1309-1323.
-
(2006)
Eur. J. Immunol
, vol.36
, pp. 1309-1323
-
-
Wolk, K.1
-
43
-
-
36048953799
-
A role for T cell-derived interleukin 22 in psoriatic skin inflammation
-
Boniface, K., et al. 2007. A role for T cell-derived interleukin 22 in psoriatic skin inflammation. Clin. Exp. Immunol. 150:407-415.
-
(2007)
Clin. Exp. Immunol
, vol.150
, pp. 407-415
-
-
Boniface, K.1
-
44
-
-
0034092634
-
International union of pharmacology. XXII. Nomenclature for chemokine receptors
-
Murphy, P.M., et al. 2000. International union of pharmacology. XXII. Nomenclature for chemokine receptors. Pharmacol. Rev. 52:145-176.
-
(2000)
Pharmacol. Rev
, vol.52
, pp. 145-176
-
-
Murphy, P.M.1
-
45
-
-
0035260881
-
Chemokines and disease
-
Gerard, C., and Rollins, B.J. 2001. Chemokines and disease. Nat. Immunol. 2:108-115.
-
(2001)
Nat. Immunol
, vol.2
, pp. 108-115
-
-
Gerard, C.1
Rollins, B.J.2
-
46
-
-
18144417512
-
Lymphocyte trafficking to inflamed skin - molecular mechanisms and implications for therapeutic target molecules
-
Schon, M.P., and Ludwig, R.J. 2005. Lymphocyte trafficking to inflamed skin - molecular mechanisms and implications for therapeutic target molecules. Expert Opin. Ther. Targets. 9:225-243.
-
(2005)
Expert Opin. Ther. Targets
, vol.9
, pp. 225-243
-
-
Schon, M.P.1
Ludwig, R.J.2
-
47
-
-
0034083091
-
The role of chemokine receptors in primary, effector, and memory immune responses
-
Sallusto, F., Mackay, C.R., and Lanzavecchia, A. 2000. The role of chemokine receptors in primary, effector, and memory immune responses. Annu. Rev. Immunol. 18:593-620.
-
(2000)
Annu. Rev. Immunol
, vol.18
, pp. 593-620
-
-
Sallusto, F.1
Mackay, C.R.2
Lanzavecchia, A.3
-
48
-
-
2142730100
-
Central memory and effector memory T cell subsets: Function, generation, and maintenance
-
Sallusto, F., Geginat, J., and Lanzavecchia, A. 2004. Central memory and effector memory T cell subsets: function, generation, and maintenance. Annu. Rev. Immunol. 22:745-763.
-
(2004)
Annu. Rev. Immunol
, vol.22
, pp. 745-763
-
-
Sallusto, F.1
Geginat, J.2
Lanzavecchia, A.3
-
49
-
-
34547734621
-
Phenotypic and functional features of human Th17 cells
-
Annunziato, F., et al. 2007. Phenotypic and functional features of human Th17 cells. J. Exp. Med. 204:1849-1861.
-
(2007)
J. Exp. Med
, vol.204
, pp. 1849-1861
-
-
Annunziato, F.1
-
50
-
-
34249079176
-
Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells
-
Acosta-Rodriguez, E.V., et al. 2007. Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells. Nat. Immunol. 8:639-646.
-
(2007)
Nat. Immunol
, vol.8
, pp. 639-646
-
-
Acosta-Rodriguez, E.V.1
-
51
-
-
40449141770
-
Human T cells that are able to produce IL-17 express the chemokine receptor CCR6
-
Singh, S.P., Zhang, H.H., Foley, J.F., Hedrick, M.N., and Farber, J.M. 2008. Human T cells that are able to produce IL-17 express the chemokine receptor CCR6. J. Immunol. 180:214-221.
-
(2008)
J. Immunol
, vol.180
, pp. 214-221
-
-
Singh, S.P.1
Zhang, H.H.2
Foley, J.F.3
Hedrick, M.N.4
Farber, J.M.5
-
52
-
-
36549019912
-
Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model
-
Hirota, K., et al. 2007. Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model. J. Exp. Med. 204:2803-2812.
-
(2007)
J. Exp. Med
, vol.204
, pp. 2803-2812
-
-
Hirota, K.1
-
53
-
-
0034660183
-
Up-regulation of macrophage inflammatory protein-3 alpha/CCL20 and CC chemokine receptor 6 in psoriasis
-
Homey, B., et al. 2000. Up-regulation of macrophage inflammatory protein-3 alpha/CCL20 and CC chemokine receptor 6 in psoriasis. J. Immunol. 164:6621-6632.
-
(2000)
J. Immunol
, vol.164
, pp. 6621-6632
-
-
Homey, B.1
-
54
-
-
0032954129
-
CC-chemokine receptor 6 is expressed on diverse memory subsets of T cells and determines responsiveness to macrophage inflammatory protein 3 alpha
-
Liao, F., et al. 1999. CC-chemokine receptor 6 is expressed on diverse memory subsets of T cells and determines responsiveness to macrophage inflammatory protein 3 alpha. J. Immunol. 162:186-194.
-
(1999)
J. Immunol
, vol.162
, pp. 186-194
-
-
Liao, F.1
-
55
-
-
33646046528
-
The vast majority of CLA+ T cells are resident in normal skin
-
Clark, R.A., et al. 2006. The vast majority of CLA+ T cells are resident in normal skin. J. Immunol. 176:4431-4439.
-
(2006)
J. Immunol
, vol.176
, pp. 4431-4439
-
-
Clark, R.A.1
-
56
-
-
9644289201
-
Homing receptor and chemokine receptor on intraepidermal T cells in psoriasis vulgaris
-
Teraki, Y., Miyake, A., Takebayashi, R., and Shiohara, T. 2004. Homing receptor and chemokine receptor on intraepidermal T cells in psoriasis vulgaris. Clin. Exp. Dermatol. 29:658-663.
-
(2004)
Clin. Exp. Dermatol
, vol.29
, pp. 658-663
-
-
Teraki, Y.1
Miyake, A.2
Takebayashi, R.3
Shiohara, T.4
-
57
-
-
68849090822
-
-
Farber, J.M. 2000. CCR6. In Cytokine reference. J.J. Oppenheim and M. Feldman, editors. Academic Press. London, United Kingdom/San Diego, California, USA. 2081-2086.
-
Farber, J.M. 2000. CCR6. In Cytokine reference. J.J. Oppenheim and M. Feldman, editors. Academic Press. London, United Kingdom/San Diego, California, USA. 2081-2086.
-
-
-
-
58
-
-
0035107851
-
CCR6-deficient mice have impaired leukocyte homeostasis and altered contact hypersensitivity and delayed-type hypersensitivity responses
-
Varona, R., et al. 2001. CCR6-deficient mice have impaired leukocyte homeostasis and altered contact hypersensitivity and delayed-type hypersensitivity responses. J. Clin. Invest. 107:R37-R45.
-
(2001)
J. Clin. Invest
, vol.107
-
-
Varona, R.1
-
59
-
-
34247859190
-
CC chemokine receptor 6 expression by B lymphocytes is essential for the development of isolated lymphoid follicles
-
McDonald, K.G., et al. 2007. CC chemokine receptor 6 expression by B lymphocytes is essential for the development of isolated lymphoid follicles. Am. J. Pathol. 170:1229-1240.
-
(2007)
Am. J. Pathol
, vol.170
, pp. 1229-1240
-
-
McDonald, K.G.1
-
60
-
-
0242303557
-
CCR6 has a non-redundant role in the development of inflammatory bowel disease
-
Varona, R., Cadenas, V., Flores, J., Martinez, A.C., and Marquez, G. 2003. CCR6 has a non-redundant role in the development of inflammatory bowel disease. Eur. J. Immunol. 33:2937-2946.
-
(2003)
Eur. J. Immunol
, vol.33
, pp. 2937-2946
-
-
Varona, R.1
Cadenas, V.2
Flores, J.3
Martinez, A.C.4
Marquez, G.5
-
61
-
-
0033679107
-
CCR6 mediates dendritic cell localization, lymphocyte homeostasis, and immune responses in mucosal tissue
-
Cook, D.N., et al. 2000. CCR6 mediates dendritic cell localization, lymphocyte homeostasis, and immune responses in mucosal tissue. Immunity. 12:495-503.
-
(2000)
Immunity
, vol.12
, pp. 495-503
-
-
Cook, D.N.1
-
62
-
-
33646566609
-
CCR6-mediated dendritic cell activation of pathogen-specific T cells in Peyer's patches
-
Salazar-Gonzalez, R.M., et al. 2006. CCR6-mediated dendritic cell activation of pathogen-specific T cells in Peyer's patches. Immunity. 24:623-632.
-
(2006)
Immunity
, vol.24
, pp. 623-632
-
-
Salazar-Gonzalez, R.M.1
-
63
-
-
39149087671
-
Essential role of CCR6 in directing activated T cells to the skin during contact hypersensitivity
-
Paradis, T.J., Cole, S.H., Nelson, R.T., and Gladue, R.P. 2008. Essential role of CCR6 in directing activated T cells to the skin during contact hypersensitivity. J. Invest. Dermatol. 128:628-633.
-
(2008)
J. Invest. Dermatol
, vol.128
, pp. 628-633
-
-
Paradis, T.J.1
Cole, S.H.2
Nelson, R.T.3
Gladue, R.P.4
-
64
-
-
22044439846
-
CCR6 regulates CD4+ T-cell-mediated acute graft-versus-host disease responses
-
Varona, R., Cadenas, V., Gomez, L., Martinez, A.C., and Marquez, G. 2005. CCR6 regulates CD4+ T-cell-mediated acute graft-versus-host disease responses. Blood. 106:18-26.
-
(2005)
Blood
, vol.106
, pp. 18-26
-
-
Varona, R.1
Cadenas, V.2
Gomez, L.3
Martinez, A.C.4
Marquez, G.5
-
65
-
-
45149109643
-
In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORgamma t+ T cells
-
Lochner, M., et al. 2008. In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORgamma t+ T cells. J. Exp. Med. 205:1381-1393.
-
(2008)
J. Exp. Med
, vol.205
, pp. 1381-1393
-
-
Lochner, M.1
-
66
-
-
33845340501
-
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene
-
Duerr, R.H., et al. 2006. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science. 314:1461-1463.
-
(2006)
Science
, vol.314
, pp. 1461-1463
-
-
Duerr, R.H.1
-
67
-
-
33749318470
-
Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides
-
Liang, S.C., et al. 2006. Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides. J. Exp. Med. 203:2271-2279.
-
(2006)
J. Exp. Med
, vol.203
, pp. 2271-2279
-
-
Liang, S.C.1
-
68
-
-
71849109959
-
Protective immunity to systemic infection with attenuated Salmonella enterica serovar enteritidis in the absence of IL-12 is associated with IL-23-dependent IL-22, but not IL-17
-
Schulz, S.M., et al. 2008. Protective immunity to systemic infection with attenuated Salmonella enterica serovar enteritidis in the absence of IL-12 is associated with IL-23-dependent IL-22, but not IL-17. J. Immunol. 181:7891-7901.
-
(2008)
J. Immunol
, vol.181
, pp. 7891-7901
-
-
Schulz, S.M.1
-
69
-
-
40049083827
-
Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens
-
Zheng, Y., et al. 2008. Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens. Nat. Med. 14:282-289.
-
(2008)
Nat. Med
, vol.14
, pp. 282-289
-
-
Zheng, Y.1
-
70
-
-
0034787546
-
Inflammatory skin disease in K14/p40 transgenic mice: Evidence for interleukin-12-like activities of p40
-
Kopp, T., et al. 2001. Inflammatory skin disease in K14/p40 transgenic mice: evidence for interleukin-12-like activities of p40. J. Invest. Dermatol. 117:618-626.
-
(2001)
J. Invest. Dermatol
, vol.117
, pp. 618-626
-
-
Kopp, T.1
-
71
-
-
0036547277
-
Expression of the C-C chemokine MIP-3 alpha/CCL20 in human epidermis with impaired permeability barrier function
-
Schmuth, M., et al. 2002. Expression of the C-C chemokine MIP-3 alpha/CCL20 in human epidermis with impaired permeability barrier function. Exp. Dermatol. 11:135-142.
-
(2002)
Exp. Dermatol
, vol.11
, pp. 135-142
-
-
Schmuth, M.1
-
72
-
-
39449101603
-
Transcriptional regulation of Th17 cell differentiation
-
Ivanov, I.I., Zhou, L., and Littman, D.R. 2007. Transcriptional regulation of Th17 cell differentiation. Semin. Immunol. 19:409-417.
-
(2007)
Semin. Immunol
, vol.19
, pp. 409-417
-
-
Ivanov, I.I.1
Zhou, L.2
Littman, D.R.3
-
73
-
-
51349111163
-
An overview of IL-17 function and signaling
-
Gaffen, S.L. 2008. An overview of IL-17 function and signaling. Cytokine. 43:402-407.
-
(2008)
Cytokine
, vol.43
, pp. 402-407
-
-
Gaffen, S.L.1
-
74
-
-
54249130813
-
Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways
-
Nograles, K.E., et al. 2008. Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways. Br. J. Dermatol. 159:1092-1102.
-
(2008)
Br. J. Dermatol
, vol.159
, pp. 1092-1102
-
-
Nograles, K.E.1
-
75
-
-
15944425718
-
CCR6 expression defines regulatory effector/memory-like cells within the CD25(+)CD4+ T-cell subset
-
Kleinewietfeld, M., et al. 2005. CCR6 expression defines regulatory effector/memory-like cells within the CD25(+)CD4+ T-cell subset. Blood. 105:2877-2886.
-
(2005)
Blood
, vol.105
, pp. 2877-2886
-
-
Kleinewietfeld, M.1
-
76
-
-
30044435436
-
Increase in TNF-alpha and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a)
-
Lowes, M.A., et al. 2005. Increase in TNF-alpha and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a). Proc. Natl. Acad. Sci. U. S. A. 102:19057-19062.
-
(2005)
Proc. Natl. Acad. Sci. U. S. A
, vol.102
, pp. 19057-19062
-
-
Lowes, M.A.1
-
77
-
-
2442658900
-
Depletion of host Langerhans cells before transplantation of donor alloreactive T cells prevents skin graft-versus-host disease
-
Merad, M., et al. 2004. Depletion of host Langerhans cells before transplantation of donor alloreactive T cells prevents skin graft-versus-host disease. Nat. Med. 10:510-517.
-
(2004)
Nat. Med
, vol.10
, pp. 510-517
-
-
Merad, M.1
-
78
-
-
32244441218
-
Dendritic cells rapidly recruited into epithelial tissues via CCR6/CCL20 are responsible for CD8+ T cell crosspriming in vivo
-
Le Borgne, M., et al. 2006. Dendritic cells rapidly recruited into epithelial tissues via CCR6/CCL20 are responsible for CD8+ T cell crosspriming in vivo. Immunity. 24:191-201.
-
(2006)
Immunity
, vol.24
, pp. 191-201
-
-
Le Borgne, M.1
-
79
-
-
59649099774
-
A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity
-
Cella, M., et al. 2009. A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity. Nature. 457:722-725.
-
(2009)
Nature
, vol.457
, pp. 722-725
-
-
Cella, M.1
-
80
-
-
57849145994
-
Influence of the transcription factor RORgammat on the development of NKp46+ cell populations in gut and skin
-
Luci, C., et al. 2009. Influence of the transcription factor RORgammat on the development of NKp46+ cell populations in gut and skin. Nat. Immunol. 10:75-82.
-
(2009)
Nat. Immunol
, vol.10
, pp. 75-82
-
-
Luci, C.1
-
81
-
-
57849117363
-
RORgammat and commensal microflora are required for the differentiation of mucosal interleukin 22-producing NKp46+ cells
-
Sanos, S.L., et al. 2009. RORgammat and commensal microflora are required for the differentiation of mucosal interleukin 22-producing NKp46+ cells. Nat. Immunol. 10:83-91.
-
(2009)
Nat. Immunol
, vol.10
, pp. 83-91
-
-
Sanos, S.L.1
-
82
-
-
57449118239
-
Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense
-
Satoh-Takayama, N., et al. 2008. Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense. Immunity. 29:958-970.
-
(2008)
Immunity
, vol.29
, pp. 958-970
-
-
Satoh-Takayama, N.1
-
83
-
-
46349097362
-
Reviews of anti-infective agents: Maraviroc: the first of a new class of antiretroviral agents
-
MacArthur, R.D., and Novak, R.M. 2008. Reviews of anti-infective agents: maraviroc: the first of a new class of antiretroviral agents. Clin. Infect. Dis. 47:236-241.
-
(2008)
Clin. Infect. Dis
, vol.47
, pp. 236-241
-
-
MacArthur, R.D.1
Novak, R.M.2
-
84
-
-
0025780879
-
Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene
-
Tybulewicz, V.L., Crawford, C.E., Jackson, P.K., Bronson, R.T., and Mulligan, R.C. 1991. Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene. Cell. 65:1153-1163.
-
(1991)
Cell
, vol.65
, pp. 1153-1163
-
-
Tybulewicz, V.L.1
Crawford, C.E.2
Jackson, P.K.3
Bronson, R.T.4
Mulligan, R.C.5
-
85
-
-
0023860003
-
Proliferin secreted by cultured cells binds to mannose 6-phosphate receptors
-
Lee, S.J., and Nathans, D. 1988. Proliferin secreted by cultured cells binds to mannose 6-phosphate receptors. J. Biol. Chem. 263:3521-3527.
-
(1988)
J. Biol. Chem
, vol.263
, pp. 3521-3527
-
-
Lee, S.J.1
Nathans, D.2
-
86
-
-
0035914841
-
The role of interleukin (IL)-10 in the persistence of Leishmania major in the skin after healing and the therapeutic potential of anti-IL-10 receptor antibody for sterile cure
-
Belkaid, Y., et al. 2001. The role of interleukin (IL)-10 in the persistence of Leishmania major in the skin after healing and the therapeutic potential of anti-IL-10 receptor antibody for sterile cure. J. Exp. Med. 194:1497-1506.
-
(2001)
J. Exp. Med
, vol.194
, pp. 1497-1506
-
-
Belkaid, Y.1
|