-
1
-
-
0037420518
-
Psoriasis
-
Lebwohl, M. Psoriasis. Lancet 361, 1197-1204 (2003).
-
(2003)
Lancet
, vol.361
, pp. 1197-1204
-
-
Lebwohl, M.1
-
2
-
-
0033748019
-
Characterization of a T cell line bearing natural killer receptors and capable of creating psoriasis in a SCID mouse model system
-
Nickoloff, B. J., Bonish, B., Huang, B. B. & Porcelli, S. A. Characterization of a T cell line bearing natural killer receptors and capable of creating psoriasis in a SCID mouse model system. J. Dermatol. Sci. 24, 212-225 (2000).
-
(2000)
J. Dermatol. Sci.
, vol.24
, pp. 212-225
-
-
Nickoloff, B.J.1
Bonish, B.2
Huang, B.B.3
Porcelli, S.A.4
-
3
-
-
0028146528
-
+ T cells in psoriatic lesions preferentially use T-cell receptor Vβ3 and/or Vβ13.1 genes
-
+ T cells in psoriatic lesions preferentially use T-cell receptor Vβ3 and/or Vβ13.1 genes. Proc. Natl Acad. Sci. USA 91, 9282-9286 (1994).
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 9282-9286
-
-
Chang, J.C.1
-
4
-
-
0032825299
-
Selection of conserved TCR VDJ rearrangements in chronic psoriatic plaques indicates a common antigen in psoriasis vulgaris
-
Prinz, J. C. et al. Selection of conserved TCR VDJ rearrangements in chronic psoriatic plaques indicates a common antigen in psoriasis vulgaris. Eur. J. Immunol. 29, 3360-3368 (1999).
-
(1999)
Eur. J. Immunol.
, vol.29
, pp. 3360-3368
-
-
Prinz, J.C.1
-
5
-
-
0035726290
-
Dominant lesional T cell receptor rearrangements persist in relapsing psoriasis but are absent from nonlesional skin: Evidence for a stable antigen-specific pathogenic T cell response in psoriasis vulgaris
-
Vollmer, S., Menssen, A. & Prinz, J. C. Dominant lesional T cell receptor rearrangements persist in relapsing psoriasis but are absent from nonlesional skin: evidence for a stable antigen-specific pathogenic T cell response in psoriasis vulgaris. J. Invest. Dermatol. 117, 1296-1301 (2001).
-
(2001)
J. Invest. Dermatol.
, vol.117
, pp. 1296-1301
-
-
Vollmer, S.1
Menssen, A.2
Prinz, J.C.3
-
6
-
-
0020595264
-
Immunocompetent cells in psoriasis. In situ immunophenotyping by monoclonal antibodies
-
Bos, J. D., Hulsebosch, H. J., Krieg, S. R., Bakker, P. M. & Cormane, R. H. Immunocompetent cells in psoriasis. In situ immunophenotyping by monoclonal antibodies. Arch. Dermatol. Res. 275, 181-189 (1983).
-
(1983)
Arch. Dermatol. Res.
, vol.275
, pp. 181-189
-
-
Bos, J.D.1
Hulsebosch, H.J.2
Krieg, S.R.3
Bakker, P.M.4
Cormane, R.H.5
-
7
-
-
84944283396
-
Cyclosporine improves psoriasis in a double-blind study
-
Ellis, C. N. et al. Cyclosporine improves psoriasis in a double-blind study. JAMA 256, 3110-3116 (1986).
-
(1986)
JAMA
, vol.256
, pp. 3110-3116
-
-
Ellis, C.N.1
-
8
-
-
0023109292
-
The effects of cyclosporin A on T lymphocyte and dendritic cell sub-populations in psoriasis
-
Baker, B. S. et al. The effects of cyclosporin A on T lymphocyte and dendritic cell sub-populations in psoriasis. Br. J. Dermatol. 116, 503-510 (1987).
-
(1987)
Br. J. Dermatol.
, vol.116
, pp. 503-510
-
-
Baker, B.S.1
-
9
-
-
0024372749
-
Immunological changes following treatment of psoriasis with cyclosporin
-
Tigalonowa, M., Bjerke, J. R., Gallati, H. & Matre, R. Immunological changes following treatment of psoriasis with cyclosporin. Acta Derm. Venereol. Suppl. (Stockh.) 146, 142-145 (1989).
-
(1989)
Acta Derm. Venereol. Suppl. (Stockh.)
, vol.146
, pp. 142-145
-
-
Tigalonowa, M.1
Bjerke, J.R.2
Gallati, H.3
Matre, R.4
-
10
-
-
0026755558
-
Tacrolimus (FK 506) - A new therapeutic agent for severe recalcitrant psoriasis
-
Jegasothy, B. V. et al. Tacrolimus (FK 506) - a new therapeutic agent for severe recalcitrant psoriasis. Arch. Dermatol. 128, 781-785 (1992).
-
(1992)
Arch. Dermatol.
, vol.128
, pp. 781-785
-
-
Jegasothy, B.V.1
-
11
-
-
0024413413
-
Remission of psoriatic lesions with muromonab-CD3 (orthoclone OKT3) treatment
-
Weinshenker, B. G., Bass, B. H., Ebers, G. C. & Rice, G. P. Remission of psoriatic lesions with muromonab-CD3 (orthoclone OKT3) treatment. J. Am. Acad. Dermatol. 20, 1132-1133 (1989).
-
(1989)
J. Am. Acad. Dermatol.
, vol.20
, pp. 1132-1133
-
-
Weinshenker, B.G.1
Bass, B.H.2
Ebers, G.C.3
Rice, G.P.4
-
12
-
-
0025862110
-
Chimaeric CD4 monoclonal antibody in treatment of generalised pustular psoriasis
-
Prinz, J. et al. Chimaeric CD4 monoclonal antibody in treatment of generalised pustular psoriasis. Lancet 338, 320-321 (1991).
-
(1991)
Lancet
, vol.338
, pp. 320-321
-
-
Prinz, J.1
-
13
-
-
0028990380
-
Response of psoriasis to a lymphocyte - Selective toxin (DAB389IL-2) suggests a primary immune, but not keratinocyte, pathogenic basis
-
Gottlieb, S. L. et al. Response of psoriasis to a lymphocyte - selective toxin (DAB389IL-2) suggests a primary immune, but not keratinocyte, pathogenic basis. Nature Med. 1, 442-447 (1995). This study provided the first evidence that disease remission could be achieved by highly selective targeting of activated T cells. The subsequent testing and development of T-cell-targeted biological drugs for the treatment of psoriasis were stimulated by this work.
-
(1995)
Nature Med.
, vol.1
, pp. 442-447
-
-
Gottlieb, S.L.1
-
14
-
-
0033135564
-
CTLA4Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris
-
Abrams, J. R. et al. CTLA4Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris. J. Clin. Invest. 103, 1243-1252 (1999).
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 1243-1252
-
-
Abrams, J.R.1
-
15
-
-
0034605033
-
Blockade of T lymphocyte costimulation with cytotoxic T lymphocyte-associated antigen 4-immunoglobulin (CTLA4Ig) reverses the cellular pathology of psoriatic plaques, including the activation of keratinocytes, dendritic cells, and endothelial cells
-
Abrams, J. R. et al. Blockade of T lymphocyte costimulation with cytotoxic T lymphocyte-associated antigen 4-immunoglobulin (CTLA4Ig) reverses the cellular pathology of psoriatic plaques, including the activation of keratinocytes, dendritic cells, and endothelial cells. J. Exp. Med. 192, 681-694 (2000).
-
(2000)
J. Exp. Med.
, vol.192
, pp. 681-694
-
-
Abrams, J.R.1
-
16
-
-
0036145337
-
The immunologic basis for the treatment of psoriasis with new biologic agents
-
Krueger, J. G. The immunologic basis for the treatment of psoriasis with new biologic agents. J. Am. Acad. Dermatol. 46, 1-23 (2002).
-
(2002)
J. Am. Acad. Dermatol.
, vol.46
, pp. 1-23
-
-
Krueger, J.G.1
-
17
-
-
12144281223
-
Psoriasis: Emerging therapeutic strategies
-
Gottlieb, A. B. Psoriasis: emerging therapeutic strategies. Nature Rev. Drug Discov. 4, 19-34 (2005). References 16 and 17 introduce more than 20 immune-targeted biological agents that have been tested as potential therapeutics for psoriasis vulgaris.
-
(2005)
Nature Rev. Drug Discov.
, vol.4
, pp. 19-34
-
-
Gottlieb, A.B.1
-
18
-
-
0030871764
-
Development of psoriasis after syngeneic bone marrow transplant from psoriatic donor: Further evidence for adoptive autoimmunity
-
Snowden, J. A. & Heaton, D. C. Development of psoriasis after syngeneic bone marrow transplant from psoriatic donor: further evidence for adoptive autoimmunity. Br. J. Dermatol. 137, 130-132 (1997).
-
(1997)
Br. J. Dermatol.
, vol.137
, pp. 130-132
-
-
Snowden, J.A.1
Heaton, D.C.2
-
19
-
-
0025086283
-
Psoriasis after allogeneic bone marrow transplantation
-
Gardembas-Pain, M. et al. Psoriasis after allogeneic bone marrow transplantation. Arch. Dermatol. 126, 1523 (1990).
-
(1990)
Arch. Dermatol.
, vol.126
, pp. 1523
-
-
Gardembas-Pain, M.1
-
20
-
-
0032712270
-
Transmission of psoriatic arthritis by allogeneic bone marrow transplantation for chronic myelogenous leukaemia from an HLA-identical donor
-
Daikeler, T., Gunaydin, I., Einsele, H., Kanz, L. & Kotter, I. Transmission of psoriatic arthritis by allogeneic bone marrow transplantation for chronic myelogenous leukaemia from an HLA-identical donor. Rheumatology (Oxford) 38, 89-90 (1999).
-
(1999)
Rheumatology (Oxford)
, vol.38
, pp. 89-90
-
-
Daikeler, T.1
Gunaydin, I.2
Einsele, H.3
Kanz, L.4
Kotter, I.5
-
21
-
-
0029861579
-
Derma injection of immunocytes induces psoriasis
-
Wrone-Smith, T. & Nickoloff, B. J. Derma injection of immunocytes induces psoriasis. J. Clin. Invest. 98, 1878-1887 (1996). This paper describes the first xenotransplantation model in which psoriasis was induced.
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 1878-1887
-
-
Wrone-Smith, T.1
Nickoloff, B.J.2
-
22
-
-
1542313881
-
Spontaneous development of psoriasis in a new animal model shows an essential role for resident T cells and tumor necrosis factor-α
-
Boyman, O. et al. Spontaneous development of psoriasis in a new animal model shows an essential role for resident T cells and tumor necrosis factor-α. J. Exp. Med. 199, 731-736 (2004). In this study, uninvolved skin grafted onto mice spontaneously becomes psoriatic, in contrast to the psoriasis that is induced in other xenotransplantation models (which require co-transfer of immune cells).
-
(2004)
J. Exp. Med.
, vol.199
, pp. 731-736
-
-
Boyman, O.1
-
23
-
-
0346963108
-
Unique keratinocyte-specific effects of interferon-γ that protect skin from viruses, identified using transcriptional profiling
-
Banno, T., Adachi, M., Mukkamala, L. & Blumenberg, M. Unique keratinocyte-specific effects of interferon-γ that protect skin from viruses, identified using transcriptional profiling. Antivir. Ther. 8, 541-554 (2003).
-
(2003)
Antivir. Ther.
, vol.8
, pp. 541-554
-
-
Banno, T.1
Adachi, M.2
Mukkamala, L.3
Blumenberg, M.4
-
24
-
-
3543047947
-
Effects of tumor necrosis factor-α (TNFα) in epidermal keratinocytes revealed using global transcriptional profiling
-
Banno, T., Gazel, A. & Blumenberg, M. Effects of tumor necrosis factor-α (TNFα) in epidermal keratinocytes revealed using global transcriptional profiling. J. Biol. Chem. 279, 32633-32642 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 32633-32642
-
-
Banno, T.1
Gazel, A.2
Blumenberg, M.3
-
25
-
-
3142514507
-
Trigger factors in childhood psoriasis and vitiligo
-
Barisic-Drusko, V. & Rucevic, I. Trigger factors in childhood psoriasis and vitiligo. Coll. Antropol. 28, 277-285 (2004).
-
(2004)
Coll. Antropol.
, vol.28
, pp. 277-285
-
-
Barisic-Drusko, V.1
Rucevic, I.2
-
26
-
-
0022618628
-
Psoriasis and α-interferon
-
Quesada, J. R. & Gutterman, J. U. Psoriasis and α-interferon. Lancet 1, 1466-1468 (1986).
-
(1986)
Lancet
, vol.1
, pp. 1466-1468
-
-
Quesada, J.R.1
Gutterman, J.U.2
-
27
-
-
10344256237
-
Psoriasis triggered by Toll-like receptor 7 agonist imiquimod in the presence of dermal plasmacytoid dendritic cell precursors
-
Gilliet, M. et al. Psoriasis triggered by Toll-like receptor 7 agonist imiquimod in the presence of dermal plasmacytoid dendritic cell precursors. Arch. Dermatol. 140, 1490-1495 (2004).
-
(2004)
Arch. Dermatol.
, vol.140
, pp. 1490-1495
-
-
Gilliet, M.1
-
28
-
-
0018552517
-
Evolution, maturation, and regression of lesions of psoriasis. New observations and correlation of clinical and histologic findings
-
Ragaz, A. & Ackerman, A. B. Evolution, maturation, and regression of lesions of psoriasis. New observations and correlation of clinical and histologic findings. Am. J. Dermatopathol. 1, 199-214 (1979).
-
(1979)
Am. J. Dermatopathol.
, vol.1
, pp. 199-214
-
-
Ragaz, A.1
Ackerman, A.B.2
-
29
-
-
0036170945
-
CCL27-CCR10 interactions regulate T cell-mediated skin inflammation
-
Homey, B. et al. CCL27-CCR10 interactions regulate T cell-mediated skin inflammation. Nature Med. 8, 157-165 (2002).
-
(2002)
Nature Med.
, vol.8
, pp. 157-165
-
-
Homey, B.1
-
30
-
-
0037453146
-
Novel mechanisms of T-cell and dendritic cell activation revealed by profiling of psoriasis on the 63,100-elementoligonucleotide array
-
Zhou, X. et al. Novel mechanisms of T-cell and dendritic cell activation revealed by profiling of psoriasis on the 63,100-elementoligonucleotide array. Physiol. Genomics 13, 69-78 (2003). This reference, together with reference 33, describes the pathogenesis of psoriasis from the genomic view. It provides the basis for the view that psoriasis is mediated by a 'type 1' pathway of inflammation and that psoriatic lesions contain organized lymphoid tissue.
-
(2003)
Physiol. Genomics
, vol.13
, pp. 69-78
-
-
Zhou, X.1
-
31
-
-
13844316466
-
Alefacept reduces infiltrating T cells, activated dendritic cells, and inflammatory genes in psoriasis vulgaris
-
Chamian, F. et al. Alefacept reduces infiltrating T cells, activated dendritic cells, and inflammatory genes in psoriasis vulgaris. Proc. Natl Acad. Sci. USA 102, 2075-2080 (2005).
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 2075-2080
-
-
Chamian, F.1
-
32
-
-
0035903305
-
Monocyte selectivity and tissue localization suggests a role for breast and kidney-expressed chemokine (BRAK) in macrophage development
-
Kurth, I. et al. Monocyte selectivity and tissue localization suggests a role for breast and kidney-expressed chemokine (BRAK) in macrophage development. J. Exp. Med. 194, 855-861 (2001).
-
(2001)
J. Exp. Med.
, vol.194
, pp. 855-861
-
-
Kurth, I.1
-
33
-
-
2342485676
-
Psoriasis vulgaris: Cutaneous lymphoid tissue supports T-cell activation and 'type 1' inflammatory gene expression
-
Lew, W., Bowcock, A. M. & Krueger, J. G. Psoriasis vulgaris: cutaneous lymphoid tissue supports T-cell activation and 'type 1' inflammatory gene expression. Trends Immunol. 25, 295-305 (2004).
-
(2004)
Trends Immunol.
, vol.25
, pp. 295-305
-
-
Lew, W.1
Bowcock, A.M.2
Krueger, J.G.3
-
35
-
-
0033953110
-
CD69, HLA-DR and the IL-2R identify persistently activated T cells in psoriasis vulgaris lesional skin: Blood and skin comparisons by flow cytometry
-
Ferenczi, K., Burack, L., Pope, M., Krueger, J. G. & Austin, L. M. CD69, HLA-DR and the IL-2R identify persistently activated T cells in psoriasis vulgaris lesional skin: blood and skin comparisons by flow cytometry. J. Autoimmun. 14, 63-78 (2000).
-
(2000)
J. Autoimmun.
, vol.14
, pp. 63-78
-
-
Ferenczi, K.1
Burack, L.2
Pope, M.3
Krueger, J.G.4
Austin, L.M.5
-
36
-
-
0032729645
-
H1 effector populations: A type 1 differentiation bias is also measured in circulating blood T cells in psoriatic patients
-
H1 effector populations: a type 1 differentiation bias is also measured in circulating blood T cells in psoriatic patients. J. Invest. Dermatol. 113, 752-759 (1999).
-
(1999)
J. Invest. Dermatol.
, vol.113
, pp. 752-759
-
-
Austin, L.M.1
Ozawa, M.2
Kikuchi, T.3
Walters, I.B.4
Krueger, J.G.5
-
38
-
-
0035725284
-
Perforin and granzyme B may contribute to skin inflammation in atopic dermatitis and psoriasis
-
Yawalkar, N., Schmid, S., Braathen, L. R. & Pichler, W. J. Perforin and granzyme B may contribute to skin inflammation in atopic dermatitis and psoriasis. Br. J. Dermatol. 144, 1133-1139 (2001).
-
(2001)
Br. J. Dermatol.
, vol.144
, pp. 1133-1139
-
-
Yawalkar, N.1
Schmid, S.2
Braathen, L.R.3
Pichler, W.J.4
-
39
-
-
0037449737
-
Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17
-
Aggarwal, S., Ghilardi, N., Xie, M. H., de Sauvage, F. J. & Gurney, A. L. Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17. J. Biol. Chem. 278, 1910-1914 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 1910-1914
-
-
Aggarwal, S.1
Ghilardi, N.2
Xie, M.H.3
De Sauvage, F.J.4
Gurney, A.L.5
-
40
-
-
0031691282
-
Interleukin-17 and interferon-γ synergize in the enhancement of proinflammatory cytokine production by human keratinocytes
-
Teunissen, M. B., Koomen, C. W., deWaal Malefyt, R., Wierenga, E. A. & Bos, J. D. Interleukin-17 and interferon-γ synergize in the enhancement of proinflammatory cytokine production by human keratinocytes. J. Invest. Dermatol. 111, 645-649 (1998).
-
(1998)
J. Invest. Dermatol.
, vol.111
, pp. 645-649
-
-
Teunissen, M.B.1
Koomen, C.W.2
DeWaal Malefyt, R.3
Wierenga, E.A.4
Bos, J.D.5
-
41
-
-
0347285359
-
Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris
-
Lee, E. et al. Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris. J. Exp. Med. 199, 125-130 (2004).
-
(2004)
J. Exp. Med.
, vol.199
, pp. 125-130
-
-
Lee, E.1
-
42
-
-
0032901103
-
Response of murine and normal human skin to injection of allogeneic blood-derived psoriatic immunocytes: Detection of T cells expressing receptors typically present on natural killer cells, including CD94, CD158, and CD161
-
Nickoloff, B. J., Wrone-Smith, T., Bonish, B. & Porcelli, S. A. Response of murine and normal human skin to injection of allogeneic blood-derived psoriatic immunocytes: detection of T cells expressing receptors typically present on natural killer cells, including CD94, CD158, and CD161. Arch. Dermatol. 135, 546-552 (1999).
-
(1999)
Arch. Dermatol.
, vol.135
, pp. 546-552
-
-
Nickoloff, B.J.1
Wrone-Smith, T.2
Bonish, B.3
Porcelli, S.A.4
-
43
-
-
0037105541
-
Susceptibility to psoriatic arthritis: Influence of activating killer Ig-like receptor genes in the absence of specific HLA-C alleles
-
Martin, M. P. et al. Susceptibility to psoriatic arthritis: influence of activating killer Ig-like receptor genes in the absence of specific HLA-C alleles. J. Immunol. 169, 2818-2822 (2002).
-
(2002)
J. Immunol.
, vol.169
, pp. 2818-2822
-
-
Martin, M.P.1
-
44
-
-
10844222790
-
high regulatory T cells in psoriasis: Mechanism underlying unrestrained pathogenic effector T cell proliferation
-
high regulatory T cells in psoriasis: mechanism underlying unrestrained pathogenic effector T cell proliferation. J. Immunol. 174, 164-173 (2005).
-
(2005)
J. Immunol.
, vol.174
, pp. 164-173
-
-
Sugiyama, H.1
-
45
-
-
0024437561
-
Characterization of factor XIIIa positive dermal dendritic cells in normal and inflamed skin
-
Cerio, R., Griffiths, C. E., Cooper, K. D., Nickoloff, B. J. & Headington, J. T. Characterization of factor XIIIa positive dermal dendritic cells in normal and inflamed skin. Br. J. Dermatol. 121, 421-431 (1989).
-
(1989)
Br. J. Dermatol.
, vol.121
, pp. 421-431
-
-
Cerio, R.1
Griffiths, C.E.2
Cooper, K.D.3
Nickoloff, B.J.4
Headington, J.T.5
-
47
-
-
18744409038
-
Plasmacytoid dendritic cells: A new cutaneous dendritic cell subset with distinct role in inflammatory skin diseases
-
Wollenberg, A. et al. Plasmacytoid dendritic cells: a new cutaneous dendritic cell subset with distinct role in inflammatory skin diseases. J. Invest. Dermatol. 119, 1096-1102 (2002).
-
(2002)
J. Invest. Dermatol.
, vol.119
, pp. 1096-1102
-
-
Wollenberg, A.1
-
48
-
-
9744265704
-
A phase I study evaluating the safety, pharmacokinetics, and clinical response of a human IL-12 p40 antibody in subjects with plaque psoriasis
-
Kauffman, C. L. et al. A phase I study evaluating the safety, pharmacokinetics, and clinical response of a human IL-12 p40 antibody in subjects with plaque psoriasis. J. Invest. Dermatol. 123, 1037-1044 (2004).
-
(2004)
J. Invest. Dermatol.
, vol.123
, pp. 1037-1044
-
-
Kauffman, C.L.1
-
49
-
-
13444269249
-
Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model
-
Sano, S. et al. Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model. Nature Med. 11, 43-49 (2005).
-
(2005)
Nature Med.
, vol.11
, pp. 43-49
-
-
Sano, S.1
-
50
-
-
19444385692
-
Stat3 regulates genes common to both wound healing and cancer
-
Dauer, D. J. et al. Stat3 regulates genes common to both wound healing and cancer. Oncogene 24, 3397-3408 (2005).
-
(2005)
Oncogene
, vol.24
, pp. 3397-3408
-
-
Dauer, D.J.1
-
51
-
-
0018243452
-
Psoriasis in an unselected series of twins
-
Brandrup, F., Hauge, M., Henningsen, K. & Eriksen, B. Psoriasis in an unselected series of twins. Arch. Dermatol. 114, 874-878 (1978).
-
(1978)
Arch. Dermatol.
, vol.114
, pp. 874-878
-
-
Brandrup, F.1
Hauge, M.2
Henningsen, K.3
Eriksen, B.4
-
52
-
-
0027305732
-
Psoriasis in Australian twins
-
Duffy, D. L., Spelman, L. S. & Martin, N. G. Psoriasis in Australian twins. J. Am. Acad. Dermatol. 29, 428-434 (1993).
-
(1993)
J. Am. Acad. Dermatol.
, vol.29
, pp. 428-434
-
-
Duffy, D.L.1
Spelman, L.S.2
Martin, N.G.3
-
53
-
-
0016029730
-
Natural history of psoriasis in 61 twin pairs
-
Farber, E. M., Nall, M. L. & Watson, W. Natural history of psoriasis in 61 twin pairs. Arch. Dermatol. 109, 207-211 (1974).
-
(1974)
Arch. Dermatol.
, vol.109
, pp. 207-211
-
-
Farber, E.M.1
Nall, M.L.2
Watson, W.3
-
54
-
-
0021518698
-
'Twin' psoriasis in monozygotic twins
-
Pisani, M. & Ruocco, V. 'Twin' psoriasis in monozygotic twins. Arch. Dermatol. 120, 1418-1419 (1984).
-
(1984)
Arch. Dermatol.
, vol.120
, pp. 1418-1419
-
-
Pisani, M.1
Ruocco, V.2
-
55
-
-
0020051265
-
Psoriasis in monozygotic twins: Variations in expression in individuals with identical genetic constitution
-
Brandrup, F., Holm, N., Grunnet, N., Henningsen, K. & Hansen, H. E. Psoriasis in monozygotic twins: variations in expression in individuals with identical genetic constitution. Acta Derm. Venereol. 62, 229-236 (1982).
-
(1982)
Acta Derm. Venereol.
, vol.62
, pp. 229-236
-
-
Brandrup, F.1
Holm, N.2
Grunnet, N.3
Henningsen, K.4
Hansen, H.E.5
-
56
-
-
2942592412
-
Psoriasis genetics: The way forward
-
Bowcock, A. M. Psoriasis genetics: the way forward. J. Invest. Dermatol. 122, xv-xvii (2004).
-
(2004)
J. Invest. Dermatol.
, vol.122
-
-
Bowcock, A.M.1
-
57
-
-
4243900858
-
A genome-wide search for susceptibility genes in human systemic lupus erythematosus sib-pair families
-
Gaffney, P. M. et al. A genome-wide search for susceptibility genes in human systemic lupus erythematosus sib-pair families. Proc. Natl Acad. Sci. USA 95, 14875-14879 (1998).
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 14875-14879
-
-
Gaffney, P.M.1
-
58
-
-
0027933734
-
A genome-wide search for human type 1 diabetes susceptibility genes
-
Davies, J. L. et al. A genome-wide search for human type 1 diabetes susceptibility genes. Nature 371, 130-136 (1994).
-
(1994)
Nature
, vol.371
, pp. 130-136
-
-
Davies, J.L.1
-
59
-
-
0037389679
-
Screening the genome for rheumatoid arthritis susceptibility genes: A replication study and combined analysis of 512 multicase families
-
Jawaheer, D. et al. Screening the genome for rheumatoid arthritis susceptibility genes: a replication study and combined analysis of 512 multicase families. Arthritis Rheum. 48, 906-916 (2003).
-
(2003)
Arthritis Rheum.
, vol.48
, pp. 906-916
-
-
Jawaheer, D.1
-
60
-
-
11144354272
-
Inflammatory bowel disease susceptibility loci defined by genome scan meta-analysis of 1952 affected relative pairs
-
van Heel, D. A. et al. Inflammatory bowel disease susceptibility loci defined by genome scan meta-analysis of 1952 affected relative pairs. Hum. Mol. Genet. 13, 763-770 (2004).
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 763-770
-
-
Van Heel, D.A.1
-
61
-
-
0018857709
-
Psoriasis and HLA-Cw6
-
Tiilikainen, A., Lassus, A., Karvonen, J., Vartiainen, P. & Julin, M. Psoriasis and HLA-Cw6. Br. J. Dermatol. 102, 179-184 (1980). This was the first study that showed the association of psoriasis with HLA-Cw6, the most highly associated classical HLA allele.
-
(1980)
Br. J. Dermatol.
, vol.102
, pp. 179-184
-
-
Tiilikainen, A.1
Lassus, A.2
Karvonen, J.3
Vartiainen, P.4
Julin, M.5
-
62
-
-
0032989175
-
Linkage disequilibrium analysis of familial psoriasis: Identification of multiple disease-associated MHC haplotypes
-
Jenisch, S. et al. Linkage disequilibrium analysis of familial psoriasis: identification of multiple disease-associated MHC haplotypes. Tissue Antigens 53, 135-146 (1999).
-
(1999)
Tissue Antigens
, vol.53
, pp. 135-146
-
-
Jenisch, S.1
-
63
-
-
0033927713
-
Localization of psoriasis-susceptibility locus PSORS1 to a 60-kb interval telomeric to HLA-C
-
Nair, R. P. et al. Localization of psoriasis-susceptibility locus PSORS1 to a 60-kb interval telomeric to HLA-C. Am. J. Hum. Genet. 66, 1833-1844 (2000). This was the first description of a dense set of microsatellite markers covering the MHC class I region and localizing PSORS1 to a particular interval in the MHC class I region.
-
(2000)
Am. J. Hum. Genet.
, vol.66
, pp. 1833-1844
-
-
Nair, R.P.1
-
64
-
-
11144297707
-
Mapping of the major psoriasis-susceptibility locus (PSORS1) in a 70-kb interval around the corneodesmosin gene (CDSN)
-
Orru, S., Giuressi, E., Carcassi, C., Casula, M. & Contu, L. Mapping of the major psoriasis-susceptibility locus (PSORS1) in a 70-kb interval around the corneodesmosin gene (CDSN). Am. J. Hum. Genet. 76 164-171 (2004).
-
(2004)
Am. J. Hum. Genet.
, vol.76
, pp. 164-171
-
-
Orru, S.1
Giuressi, E.2
Carcassi, C.3
Casula, M.4
Contu, L.5
-
65
-
-
18544383722
-
Family-based analysis using a dense single-nucleotide polymorphism-based map defines genetic variation at PSORS1, the major psoriasis-susceptibility locus
-
Veal, C. D. et al. Family-based analysis using a dense single-nucleotide polymorphism-based map defines genetic variation at PSORS1, the major psoriasis-susceptibility locus. Am. J. Hum. Genet. 71, 554-564 (2002).
-
(2002)
Am. J. Hum. Genet.
, vol.71
, pp. 554-564
-
-
Veal, C.D.1
-
66
-
-
30744467393
-
HLA class I associations and psoriasis susceptibility; an integration of classical markers and SNPs
-
in the press
-
Helms, C. et al. HLA class I associations and psoriasis susceptibility; an integration of classical markers and SNPs. Hum. Genet. (in the press).
-
Hum. Genet.
-
-
Helms, C.1
-
67
-
-
18344372557
-
Coding haplotype analysis supports HCR as the putative susceptibility gene for psoriasis at the MHC PSORS1 locus
-
Asumalahti, K. et al. Coding haplotype analysis supports HCR as the putative susceptibility gene for psoriasis at the MHC PSORS1 locus. Hum. Mol. Genet. 11, 589-597 (2002).
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 589-597
-
-
Asumalahti, K.1
-
68
-
-
0034640870
-
A candidate gene for psoriasis near HLA-C, HCR (Pg8), is highly polymorphic with a disease-associated susceptibility allele
-
Asumalahti, K. et al. A candidate gene for psoriasis near HLA-C, HCR (Pg8), is highly polymorphic with a disease-associated susceptibility allele. Hum. Mol. Genet. 9, 1533-1542 (2000).
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 1533-1542
-
-
Asumalahti, K.1
-
69
-
-
4344600503
-
Transgenic mouse models support HCR as an effector gene in the PSORS1 locus
-
Elomaa, O. et al. Transgenic mouse models support HCR as an effector gene in the PSORS1 locus. Hum. Mol. Genet. 13, 1551-1561 (2004).
-
(2004)
Hum. Mol. Genet.
, vol.13
, pp. 1551-1561
-
-
Elomaa, O.1
-
70
-
-
0033535803
-
A non-HLA gene within the MHC in psoriasis
-
Allen, M. H. et al. A non-HLA gene within the MHC in psoriasis. Lancet 353, 1589-1590 (1999). This paper provided the first indication that a gene in the MHC class I region other than HLA-C is responsible for susceptibility to psoriasis.
-
(1999)
Lancet
, vol.353
, pp. 1589-1590
-
-
Allen, M.H.1
-
71
-
-
0034943350
-
Corneodesmosin expression in psoriasis vulgaris differs from normal skin and other inflammatory skin disorders
-
Allen, M. et al. Corneodesmosin expression in psoriasis vulgaris differs from normal skin and other inflammatory skin disorders. Lab. Invest. 81, 969-976 (2001).
-
(2001)
Lab. Invest.
, vol.81
, pp. 969-976
-
-
Allen, M.1
-
72
-
-
0344142484
-
Novel genetic association between the corneodesmosin (MHC S) gene and susceptibility to psoriasis
-
Tazi Ahnini, R. et al. Novel genetic association between the corneodesmosin (MHC S) gene and susceptibility to psoriasis. Hum. Mol. Genet. 8, 1135-1140 (1999).
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 1135-1140
-
-
Tazi Ahnini, R.1
-
73
-
-
0035827559
-
Refined characterization of corneodesmosin proteolysis during terminal differentiation of human epidermis and its relationship to desquamation
-
Simon, M. et al. Refined characterization of corneodesmosin proteolysis during terminal differentiation of human epidermis and its relationship to desquamation. J. Biol. Chem. 276, 20292-20299 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 20292-20299
-
-
Simon, M.1
-
74
-
-
0037085257
-
Corneodesmosin, a component of epidermal corneocyte desmosomes, displays homophilic adhesive properties
-
Jonca, N. et al. Corneodesmosin, a component of epidermal corneocyte desmosomes, displays homophilic adhesive properties. J. Biol. Chem. 277, 5024-5029 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 5024-5029
-
-
Jonca, N.1
-
75
-
-
0035130671
-
Identification of six novel polymorphisms in the human corneodesmosin gene
-
Guerrin, M. et al. Identification of six novel polymorphisms in the human corneodesmosin gene. Tissue Antigens 57, 32-38 (2001).
-
(2001)
Tissue Antigens
, vol.57
, pp. 32-38
-
-
Guerrin, M.1
-
76
-
-
1842639321
-
A 4.2 kb upstream region of the human corneodesmosin gene directs site-specific expression in hair follicles and hyperkeratotic epidermis of transgenic mice
-
Gallinaro, H. et al. A 4.2 kb upstream region of the human corneodesmosin gene directs site-specific expression in hair follicles and hyperkeratotic epidermis of transgenic mice. J. Invest. Dermatol. 122, 730-738 (2004).
-
(2004)
J. Invest. Dermatol.
, vol.122
, pp. 730-738
-
-
Gallinaro, H.1
-
77
-
-
0028366154
-
Gene for familial psoriasis susceptibility mapped to the distal end of human chromosome 17q
-
Tomfohrde, J. et al. Gene for familial psoriasis susceptibility mapped to the distal end of human chromosome 17q. Science 264, 1141-1145 (1994). This was the first study that indicated that a locus other than the MHC locus could contribute to susceptibility to psoriasis.
-
(1994)
Science
, vol.264
, pp. 1141-1145
-
-
Tomfohrde, J.1
-
78
-
-
0345659216
-
A putative RUNX1 binding site variant between SLC9A3R1 and NAT9 is associated with susceptibility to psoriasis
-
Helms, C. et al. A putative RUNX1 binding site variant between SLC9A3R1 and NAT9 is associated with susceptibility to psoriasis. Nature Genet. 35, 349-356 (2003). This study used family-based association mapping to identify a common variant for susceptibility to psoriasis that alters a RUNX-binding site and potentially affects immunological-synapse formation by altered regulation of SLC3A3R1.
-
(2003)
Nature Genet.
, vol.35
, pp. 349-356
-
-
Helms, C.1
-
79
-
-
0030608877
-
Identification of EBP50: A PDZ-containing phosphoprotein that associates with members of the ezrin-radixin-moesin family
-
Reczek, D., Berryman, M. & Bretscher, A. Identification of EBP50: a PDZ-containing phosphoprotein that associates with members of the ezrin-radixin-moesin family. J. Cell Biol. 139, 169-179 (1997).
-
(1997)
J. Cell Biol.
, vol.139
, pp. 169-179
-
-
Reczek, D.1
Berryman, M.2
Bretscher, A.3
-
80
-
-
0033570051
-
+ exchanger isoform NHE3 is regulated by the actin cytoskeleton
-
+ exchanger isoform NHE3 is regulated by the actin cytoskeleton. J. Biol. Chem. 274, 29843-29849 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 29843-29849
-
-
Kurashima, K.1
-
81
-
-
0037080345
-
Negative regulation of immune synapse formation by anchoring lipid raft to cytoskeleton through Cbp-EBP50-ERM assembly
-
Itoh, K. et al. Negative regulation of immune synapse formation by anchoring lipid raft to cytoskeleton through Cbp-EBP50-ERM assembly. J. Immunol. 168, 541-544 (2002).
-
(2002)
J. Immunol.
, vol.168
, pp. 541-544
-
-
Itoh, K.1
-
82
-
-
0035059418
-
The immunological synapse
-
Bromley, S. K. et al. The immunological synapse. Annu. Rev. Immunol. 19, 375-396 (2001).
-
(2001)
Annu. Rev. Immunol.
, vol.19
, pp. 375-396
-
-
Bromley, S.K.1
-
83
-
-
0037340388
-
The nature of molecular recognition by T cells
-
Davis, S. J. et al. The nature of molecular recognition by T cells. Nature Immunol. 4, 217-224 (2003).
-
(2003)
Nature Immunol.
, vol.4
, pp. 217-224
-
-
Davis, S.J.1
-
84
-
-
0037370491
-
Phosphorylation-dependent regulation of T-cell activation by PAG/Cbp, a lipid raft-associated transmembrane adaptor
-
Davidson, D., Bakinowski, M., Thomas, M. L., Horejsi, V. & Veillette, A. Phosphorylation-dependent regulation of T-cell activation by PAG/Cbp, a lipid raft-associated transmembrane adaptor. Mol. Cell. Biol. 23, 2017-2028 (2003).
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 2017-2028
-
-
Davidson, D.1
Bakinowski, M.2
Thomas, M.L.3
Horejsi, V.4
Veillette, A.5
-
85
-
-
0037178786
-
mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery
-
Kim, D. H. et al. mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. Cell 110, 163-175 (2002).
-
(2002)
Cell
, vol.110
, pp. 163-175
-
-
Kim, D.H.1
-
86
-
-
0037178781
-
Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action
-
Hara, K. et al. Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action. Cell 110, 177-189 (2002).
-
(2002)
Cell
, vol.110
, pp. 177-189
-
-
Hara, K.1
-
87
-
-
2942714992
-
Genetic analysis of PSORS2 markers in a UK dataset supports the association between RAPTOR SNPs and familial psoriasis
-
Capon, F. et al. Genetic analysis of PSORS2 markers in a UK dataset supports the association between RAPTOR SNPs and familial psoriasis. J. Med. Genet. 41, 459-460 (2004).
-
(2004)
J. Med. Genet.
, vol.41
, pp. 459-460
-
-
Capon, F.1
-
88
-
-
13444306425
-
Mapping of psoriasis to 17q terminus
-
Hwu, W. L. et al. Mapping of psoriasis to 17q terminus. J. Med. Genet. 42, 152-158 (2005).
-
(2005)
J. Med. Genet.
, vol.42
, pp. 152-158
-
-
Hwu, W.L.1
-
89
-
-
0032900956
-
Searching for psoriasis susceptibility genes in Italy: Genome scan and evidence for a new locus on chromosome 1
-
Capon, F. et al. Searching for psoriasis susceptibility genes in Italy: genome scan and evidence for a new locus on chromosome 1. J. Invest. Dermatol. 112, 32-35 (1999).
-
(1999)
J. Invest. Dermatol.
, vol.112
, pp. 32-35
-
-
Capon, F.1
-
90
-
-
0031708739
-
The genetics of psoriasis: A complex disorder of the skin and immune system
-
Bhalerao, J. & Bowcock, A. M. The genetics of psoriasis: a complex disorder of the skin and immune system. Hum. Mol. Genet. 7, 1537-1545 (1998).
-
(1998)
Hum. Mol. Genet.
, vol.7
, pp. 1537-1545
-
-
Bhalerao, J.1
Bowcock, A.M.2
-
91
-
-
3042688916
-
S100 proteins in the epidermis
-
Eckert, R. L. et al. S100 proteins in the epidermis. J. Invest. Dermatol. 123, 23-33 (2004).
-
(2004)
J. Invest. Dermatol.
, vol.123
, pp. 23-33
-
-
Eckert, R.L.1
-
92
-
-
0033753242
-
Expression of small proline rich proteins in neoplastic and inflammatory skin diseases
-
De Heller-Milev, M., Huber, M., Panizzon, R. & Hohl, D. Expression of small proline rich proteins in neoplastic and inflammatory skin diseases. Br. J. Dermatol. 143, 733-740 (2000).
-
(2000)
Br. J. Dermatol.
, vol.143
, pp. 733-740
-
-
De Heller-Milev, M.1
Huber, M.2
Panizzon, R.3
Hohl, D.4
-
93
-
-
0035818472
-
Differentially expressed late constituents of the epidermal cornified envelope
-
Marshall, D., Hardman, M. J., Nield, K. M. & Byrne, C. Differentially expressed late constituents of the epidermal cornified envelope. Proc. Natl Acad. Sci. USA 98, 13031-13036 (2001).
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 13031-13036
-
-
Marshall, D.1
Hardman, M.J.2
Nield, K.M.3
Byrne, C.4
-
94
-
-
18344392840
-
Identification of a psoriasis susceptibility candidate gene by linkage disequilibrium mapping with a localized single nucleotide polymorphism map
-
Hewett, D. et al. Identification of a psoriasis susceptibility candidate gene by linkage disequilibrium mapping with a localized single nucleotide polymorphism map. Genomics 79, 305-314 (2002). This was the first example of potential identification of a psoriasis-susceptibility gene by association studies with SNPs.
-
(2002)
Genomics
, vol.79
, pp. 305-314
-
-
Hewett, D.1
-
95
-
-
1242295174
-
Molecular physiology of cation-coupled Cl- Cotransport: The SLC12 family
-
Hebert, S. C., Mount, D. B. & Gamba, G. Molecular physiology of cation-coupled Cl- cotransport: the SLC12 family. Pflugers Arch. 447, 580-593 (2004).
-
(2004)
Pflugers Arch.
, vol.447
, pp. 580-593
-
-
Hebert, S.C.1
Mount, D.B.2
Gamba, G.3
-
96
-
-
0344364566
-
An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis
-
Tokuhiro, S. et al. An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis. Nature Genet. 35, 341-348 (2003).
-
(2003)
Nature Genet.
, vol.35
, pp. 341-348
-
-
Tokuhiro, S.1
-
97
-
-
2442585704
-
Functional variants of OCTN cation transporter genes are associated with Crohn disease
-
Peltekova, V. D. et al. Functional variants of OCTN cation transporter genes are associated with Crohn disease. Nature Genet. 36, 471-475 (2004).
-
(2004)
Nature Genet.
, vol.36
, pp. 471-475
-
-
Peltekova, V.D.1
-
98
-
-
10744227996
-
PDZK1: I. A major scaffolder in brush borders of proximal tubular cells
-
Gisler, S. M. et al. PDZK1: I. A major scaffolder in brush borders of proximal tubular cells. Kidney Int. 64, 1733-1745 (2003).
-
(2003)
Kidney Int.
, vol.64
, pp. 1733-1745
-
-
Gisler, S.M.1
-
99
-
-
0032544004
-
Clustering of non-major histocompatibility complex susceptibility candidate loci in human autoimmune diseases
-
Becker, K. G. et al. Clustering of non-major histocompatibility complex susceptibility candidate loci in human autoimmune diseases. Proc. Natl Acad. Sci. USA 95, 9979-9984 (1998). This study indicates that there is an overlap in the locations of disease-susceptibility loci for several autoimmune diseases, including psoriasis.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 9979-9984
-
-
Becker, K.G.1
-
100
-
-
0033795055
-
Genomewide scan in German families reveals evidence for a novel psoriasis-susceptibility locus on chromosome 19p13
-
Lee, Y. A. et al. Genomewide scan in German families reveals evidence for a novel psoriasis-susceptibility locus on chromosome 19p13. Am. J. Hum. Genet. 67, 1020-1024 (2000).
-
(2000)
Am. J. Hum. Genet.
, vol.67
, pp. 1020-1024
-
-
Lee, Y.A.1
-
101
-
-
2442530967
-
Inflammatory bowel disease is linked to 19p13 and associated with ICAM-1
-
Low, J. H. et al. Inflammatory bowel disease is linked to 19p13 and associated with ICAM-1. Inflamm. Bowel Dis. 10, 173-181 (2004).
-
(2004)
Inflamm. Bowel Dis.
, vol.10
, pp. 173-181
-
-
Low, J.H.1
-
102
-
-
4344675699
-
A genome-wide scan for juvenile rheumatoid arthritis in affected sibpair families provides evidence of linkage
-
Thompson, S. D. et al. A genome-wide scan for juvenile rheumatoid arthritis in affected sibpair families provides evidence of linkage. Arthritis Rheum. 50, 2920-2930 (2004).
-
(2004)
Arthritis Rheum.
, vol.50
, pp. 2920-2930
-
-
Thompson, S.D.1
-
103
-
-
0141817736
-
A major non-HLA locus in celiac disease maps to chromosome 19
-
Van Belzen, M. J. et al. A major non-HLA locus in celiac disease maps to chromosome 19. Gastroenteroiogy 125, 1032-1041 (2003).
-
(2003)
Gastroenteroiogy
, vol.125
, pp. 1032-1041
-
-
Van Belzen, M.J.1
-
104
-
-
10644221868
-
Genetic variants of Complex I in multiple sclerosis
-
Vyshkina, T., Banisor, I., Shugart, Y. Y., Last, T. P. & Kaiman, B. Genetic variants of Complex I in multiple sclerosis. J. Neurol. Sci. 228, 55-64 (2005).
-
(2005)
J. Neurol. Sci.
, vol.228
, pp. 55-64
-
-
Vyshkina, T.1
Banisor, I.2
Shugart, Y.Y.3
Last, T.P.4
Kaiman, B.5
-
105
-
-
10744233878
-
Association of intercellular adhesion molecule-1 gene with type 1 diabetes
-
Nejentsev, S. et al. Association of intercellular adhesion molecule-1 gene with type 1 diabetes. Lancet 362, 1723-1724 (2003).
-
(2003)
Lancet
, vol.362
, pp. 1723-1724
-
-
Nejentsev, S.1
-
106
-
-
2442530967
-
Inflammatory bowel disease is linked to 19p13 and associated with ICAM-1
-
Low, J. H. et al. Inflammatory bowel disease is linked to 19p13 and associated with ICAM-1. Inflamm. Bowel Dis. 10, 173-181 (2004).
-
(2004)
Inflamm. Bowel Dis.
, vol.10
, pp. 173-181
-
-
Low, J.H.1
-
107
-
-
13844292408
-
Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus
-
Sigurdsson, S. et al. Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus. Am. J. Hum. Genet. 76, 528-537 (2005).
-
(2005)
Am. J. Hum. Genet.
, vol.76
, pp. 528-537
-
-
Sigurdsson, S.1
-
108
-
-
0035072326
-
Genetic linkage of childhood atopic dermatitis to psoriasis susceptibility loci
-
Cookson, W. O. et al. Genetic linkage of childhood atopic dermatitis to psoriasis susceptibility loci. Nature Genet. 27, 372-373 (2001). This was the first report that showed that there is an overlap between the genetic loci that confer susceptibility to psoriasis and another inflammatory skin disease, atopic dermatitis.
-
(2001)
Nature Genet.
, vol.27
, pp. 372-373
-
-
Cookson, W.O.1
-
109
-
-
0037219893
-
A susceptibility gene for psoriatic arthritis maps to chromosome 16q: Evidence for imprinting
-
Karason, A. et al. A susceptibility gene for psoriatic arthritis maps to chromosome 16q: evidence for imprinting. Am. J. Hum. Genet. 72, 125-131 (2003).
-
(2003)
Am. J. Hum. Genet.
, vol.72
, pp. 125-131
-
-
Karason, A.1
-
110
-
-
14744278597
-
Molecular mechanisms that set the stage for DC-T cell engagement
-
van Gisbergen, K. P., Paessens, L. C., Geijtenbeek, T. B. & van Kooyk, Y. Molecular mechanisms that set the stage for DC-T cell engagement. Immunol. Lett. 97, 199-208 (2005).
-
(2005)
Immunol. Lett.
, vol.97
, pp. 199-208
-
-
Van Gisbergen, K.P.1
Paessens, L.C.2
Geijtenbeek, T.B.3
Van Kooyk, Y.4
-
111
-
-
0347122087
-
Hsp70 promotes antigen-presenting cell function and converts T-cell tolerance to autoimmunity in vivo
-
Millar, D. G. et al. Hsp70 promotes antigen-presenting cell function and converts T-cell tolerance to autoimmunity in vivo. Nature Med. 9, 1469-1476 (2003).
-
(2003)
Nature Med.
, vol.9
, pp. 1469-1476
-
-
Millar, D.G.1
-
112
-
-
3242713277
-
A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis
-
Begovich, A. B. et al. A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis. Am. J. Hum. Genet. 75, 330-337 (2004).
-
(2004)
Am. J. Hum. Genet.
, vol.75
, pp. 330-337
-
-
Begovich, A.B.1
-
113
-
-
12144291502
-
A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes
-
Bottini, N. et al. A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes. Nature Genet. 36, 337-338 (2004).
-
(2004)
Nature Genet.
, vol.36
, pp. 337-338
-
-
Bottini, N.1
-
114
-
-
4143105691
-
Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE
-
Kyogoku, C. et al. Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE. Am. J. Hum. Genet. 75, 504-507 (2004).
-
(2004)
Am. J. Hum. Genet.
, vol.75
, pp. 504-507
-
-
Kyogoku, C.1
-
115
-
-
0035367576
-
Proximal protein tyrosine kinases in immunoreceptor signaling
-
Latour, S. & Veillette, A. Proximal protein tyrosine kinases in immunoreceptor signaling. Curr. Opin. Immunol. 13, 299-306 (2001).
-
(2001)
Curr. Opin. Immunol.
, vol.13
, pp. 299-306
-
-
Latour, S.1
Veillette, A.2
-
116
-
-
0037091012
-
Mutations in CD2BP1 disrupt binding to PTP PEST and are responsible for PAPA syndrome, an autoinflammatory disorder
-
Wise, C. A. et al. Mutations in CD2BP1 disrupt binding to PTP PEST and are responsible for PAPA syndrome, an autoinflammatory disorder. Hum. Mol. Genet. 11, 961-969 (2002).
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 961-969
-
-
Wise, C.A.1
-
117
-
-
0344823965
-
Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway
-
Shoham, N. G. et al. Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway. Proc. Natl. Acad. Sci. USA 100, 13501-13506 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 13501-13506
-
-
Shoham, N.G.1
-
118
-
-
2642575164
-
Association of the PD-1.3SA allele of the PDCD1 gene in patients with rheumatoid arthritis negative for rheumatoid factor and the shared epitope
-
Prokunina, L. et al. Association of the PD-1.3SA allele of the PDCD1 gene in patients with rheumatoid arthritis negative for rheumatoid factor and the shared epitope. Arthritis Rheum. 50, 1770-1773 (2004).
-
(2004)
Arthritis Rheum.
, vol.50
, pp. 1770-1773
-
-
Prokunina, L.1
-
119
-
-
0037648405
-
Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease
-
Ueda, H. et al. Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. Nature 423, 506-511 (2003).
-
(2003)
Nature
, vol.423
, pp. 506-511
-
-
Ueda, H.1
-
120
-
-
3543046736
-
A functional variant of SUMO4, a new IκBα modifier, is associated with type 1 diabetes
-
Guo, D. et al. A functional variant of SUMO4, a new IκBα modifier, is associated with type 1 diabetes. Nature Genet. 36, 837-841 (2004).
-
(2004)
Nature Genet.
, vol.36
, pp. 837-841
-
-
Guo, D.1
-
121
-
-
13244277850
-
A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans
-
Prokunina, L. et al. A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans. Nature Genet. 32, 666-669 (2002).
-
(2002)
Nature Genet.
, vol.32
, pp. 666-669
-
-
Prokunina, L.1
-
122
-
-
0037100461
-
Runx1 is essential for hematopoietic commitment at the hemangioblast stage of development in vitro
-
Lacaud, G. et al. Runx1 is essential for hematopoietic commitment at the hemangioblast stage of development in vitro. Blood 100, 458-466 (2002).
-
(2002)
Blood
, vol.100
, pp. 458-466
-
-
Lacaud, G.1
-
123
-
-
8644220506
-
Loss of Runx3 function in leukocytes is associated with spontaneously developed colitis and gastric mucosal hyperplasia
-
Brenner, O. et al. Loss of Runx3 function in leukocytes is associated with spontaneously developed colitis and gastric mucosal hyperplasia. Proc. Natl Acad. Sci. USA 101, 16016-16021 (2004).
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 16016-16021
-
-
Brenner, O.1
-
124
-
-
0030664602
-
Transgenic expression of the human amphiregulin gene induces a psoriasis-like phenotype
-
Cook, P. W. et al. Transgenic expression of the human amphiregulin gene induces a psoriasis-like phenotype. J. Clin. Invest. 100, 2286-2294 (1997).
-
(1997)
J. Clin. Invest.
, vol.100
, pp. 2286-2294
-
-
Cook, P.W.1
-
125
-
-
0038644624
-
Transgenic delivery of VEGF to mouse skin leads to an inflammatory condition resembling human psoriasis
-
Xia, Y. P. et al. Transgenic delivery of VEGF to mouse skin leads to an inflammatory condition resembling human psoriasis. Blood 102, 161-168 (2003).
-
(2003)
Blood
, vol.102
, pp. 161-168
-
-
Xia, Y.P.1
-
126
-
-
0038189842
-
IL-23 production by cosecretion of endogenous p19 and transgenic p40 in keratin 14/p40 transgenic mice: Evidence for enhanced cutaneous immunity
-
Kopp, T. et al. IL-23 production by cosecretion of endogenous p19 and transgenic p40 in keratin 14/p40 transgenic mice: evidence for enhanced cutaneous immunity. J. Immunol. 170, 5438-5444 (2003).
-
(2003)
J. Immunol.
, vol.170
, pp. 5438-5444
-
-
Kopp, T.1
-
127
-
-
3843120939
-
Induction of cutaneous delayed-type hypersensitivity reactions in VEGF-A transgenic mice results in chronic skin inflammation associated with persistent lymphatic hyperplasia
-
Kunstfeld, R. et al. Induction of cutaneous delayed-type hypersensitivity reactions in VEGF-A transgenic mice results in chronic skin inflammation associated with persistent lymphatic hyperplasia. Blood 104, 1048-1057 (2004).
-
(2004)
Blood
, vol.104
, pp. 1048-1057
-
-
Kunstfeld, R.1
-
128
-
-
0029565083
-
Suprabasal integrin expression in the epidermis of transgenic mice results in developmental defects and a phenotype resembling psoriasis
-
Carroll, J. M., Romero, M. R. & Watt, F. M. Suprabasal integrin expression in the epidermis of transgenic mice results in developmental defects and a phenotype resembling psoriasis. Cell 83, 957-968 (1995).
-
(1995)
Cell
, vol.83
, pp. 957-968
-
-
Carroll, J.M.1
Romero, M.R.2
Watt, F.M.3
-
129
-
-
0033635304
-
+T cell-mediated skin disease in mice lacking IRF-2, the transcriptional attenuator of interferon-α/β signaling
-
+T cell-mediated skin disease in mice lacking IRF-2, the transcriptional attenuator of interferon-α/β signaling. Immunity 13, 643-655 (2000).
-
(2000)
Immunity
, vol.13
, pp. 643-655
-
-
Hida, S.1
-
131
-
-
0030060392
-
T cells, but not thymic exposure to HLA-B27, are required for the inflammatory disease of HLA-B27 transgenic rats
-
Breban, M. et al. T cells, but not thymic exposure to HLA-B27, are required for the inflammatory disease of HLA-B27 transgenic rats. J. Immunol. 156, 794-803 (1996).
-
(1996)
J. Immunol.
, vol.156
, pp. 794-803
-
-
Breban, M.1
-
132
-
-
17744373448
-
Interleukin 20: Discovery, receptor identification, and role in epidermal function
-
Blumberg, H. et al. Interleukin 20: discovery, receptor identification, and role in epidermal function. Cell 104, 9-19 (2001).
-
(2001)
Cell
, vol.104
, pp. 9-19
-
-
Blumberg, H.1
-
133
-
-
0027468283
-
Targeting expression of keratinocyte growth factor to keratinocytes elicits striking changes in epithelial differentiation in transgenic mice
-
Guo, L., Yu, Q. C. & Fuchs, E. Targeting expression of keratinocyte growth factor to keratinocytes elicits striking changes in epithelial differentiation in transgenic mice. EMBO J. 12, 973-986 (1993).
-
(1993)
EMBO J.
, vol.12
, pp. 973-986
-
-
Guo, L.1
Yu, Q.C.2
Fuchs, E.3
|