Up-regulation of macrophage inflammatory protein-3α/CCL20 and CC chemokine receptor 6 in psoriasis

Journal of Immunology

Volumn 164, Issue 12, 2000, Pages 6621-6632

  Homey, Bernhard ^a   Dieu Nosjean, Marie Caroline ^a   Wiesenborn, Andrea ^b   Massacrier, Catherine ^a   Pin, Jean Jacques ^a   Oldham, Elizabeth ^a   Catron, Daniel ^a   Buchanan, Matthew E ^a   Müller, Anja ^a   De Waal Malefyt, Rene ^a   Deng, Glenn ^a   Orozco, Rocio ^c   Ruzicka, Thomas ^b   Lehmann, Percy ^b   Lebecque, Serge ^a   Caux, Christophe ^a   Zlotnik, Albert ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b HEINRICH HEINE UNIVERSITY   (Germany)

^c INSTITUTO NACIONAL DE CIENCIAS MÉDICAS Y NUTRICIÓN SALVADOR ZUBIRÁN   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CHEMOKINE; CHEMOKINE RECEPTOR; MACROPHAGE INFLAMMATORY PROTEIN; MESSENGER RNA;

ARTICLE; AUTOIMMUNITY; CONTROLLED STUDY; DENDRITIC CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOPATHOGENESIS; KERATINOCYTE; MEMORY CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PSORIASIS; VASCULAR ENDOTHELIUM;

EID: 0034660183     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.164.12.6621     Document Type: Article

References (61)

1. Ortonne, J. P. 1996, Aetiology and pathogenesis of psoriasis. Br. J. Dermatol. 135(Suppl. 49):1.
2. Prens, E., R. Debets, and J. Hegmans. 1995. T lymphocytes in psoriasis. Clin. Dermatol. 13:115.
3. Elder, J. T., R. P. Nair, and J. J. Voorhees. 1994. Epidemiology and the genetics of psoriasis. J. Invest. Dermatol. 102:24S.
4. Gottlieb, S. L., P. Gilleaudeau, R. Johnson, L. Estes, T. G. Woodworth, A. B. Gottlieb, and J. G. Krueger. 1995. Response of psoriasis to a lymphocyte-selective toxin (DAB389IL-2) suggests a primary immune, but not keratinocyte, pathogenic basis. Nat. Med. 1:441.
5. Nicolas, J. F., N. Chamchick, J. Thivolet, J. Wijdenes, P. Morel, and J. P. Revillard. 1991. CD4 antibody treatment of severe psoriasis. Lancet 338: 321.
6. Cooper, K. D., J. J. Voorhees, G. J. Fisher, L. S. Chan, A. K. Gupta, and O. Baadsgaard. 1990. Effects of cyclosporine on immunologic mechanisms in psoriasis. J. Am. Acad. Dermatol. 23:1318.
7. Ellis, C. N., D. C. Gorsulowsky, T. A. Hamilton, J. K. Billings, M. D. Brown, J. T. Headington, K. D. Cooper, O. Baadsgaard, E. A. Duell, T. M. Annesley, et al. 1986. Cyclosporine improves psoriasis in a double-blind study. J. Am. Med. Assoc. 256:3110.
8. Krueger, J. G., J. T. Wolfe, R. T. Nabeya, V. P. Vallat, P. Gilleaudeau, N. S. Heftler, L. M. Austin, and A. B. Gottlieb. 1995. Successful ultraviolet B treatment of psoriasis is accompanied by a reversal of keratinocyte pathology and by selective depletion of intraepidermal T cells. J. Exp. Med. 182:2057.
9. + T cells. Nat. Med. 3:183.
10. Schon, M. P. 1999. Animal models of psoriasis: what can we learn from them? J. Invest. Dermatol. 112:405.
11. Wrone-Smith, T., and B. J. Nickoloff. 1996. Dermal injection of immunocytes induces psoriasis. J. Clin. Invest. 98:1878.
12. Uyemura, K., M. Yamamura, D. F. Fivenson, R. L. Modlin, and B. J. Nickoloff. 1993. The cytokine network in lesional and lesion-free psoriatic skin is characterized by a T-helper type 1 cell-mediated response. J. Invest. Dermatol. 101:701.
13. Barker, J. N. 1998. Psoriasis as a T cell-mediated autoimmune disease. Hosp. Med. 59:530.
14. + T cells induces psoriasis. Am. J. Pathol. 151:145.
15. Bata-Csorgo, Z., C. Hammerberg, J. J. Voorhees, and K. D. Cooper. 1995. Intralesional T-lymphocyte activation as a mediator of psoriatic epidermal hyperplasia. J. Invest. Dermatol. 105:895.
16. Zlotnik, A., and O. Yoshie. 2000. Chemokines and immunity. Immunity. 12:121.
17. Rossi, D. L., A. P. Vicari, K. Franz-Bacon, T. K. McClanahan, and A. Zlotnik. 1997. Identification through bioinformatics of two new macrophage proinflammatory human chemokines: MIP-3α and MIP-3β. J. Immunol. 158:1033.
18. Greaves, D. R., W. Wang, D. J. Dairaghi, M. C. Dieu, B. Saint-Vis, K. Franz-Bacon, D. Rossi, C. Caux, T. McClanahan, S. Gordon, et al. 1997. CCR6, a CC chemokine receptor that interacts with macrophage inflammatory protein 3α and is highly expressed in human dendritic cells. J. Exp. Med. 186: 837.
19. Dieu, M. C., B. Vanbervliet, A. Vicari, J. M. Bridon, E. Oldham, S. Ait-Yahia, F. Briere, A. Zlotnik, S. Lebecque, and C. Caux. 1998. Selective recruitment of immature and mature dendritic cells by distinct chemokines expressed in different anatomic sites. J. Exp. Med. 188:373.
20. Power, C. A., D. J. Church, A. Meyer, S. Alouani, A. E. Proudfoot, I. Clark-Lewis, S. Sozzani, A. Mantovani, and T. N. Wells. 1997. Cloning and characterization of a specific receptor for the novel CC chemokine MIP-3α from lung dendritic cells. J. Exp. Med. 186:825.
21. Liao, F., R. L. Rabin, C. S. Smith, G. Sharma, T. B. Nutman, and J. M. Farber. 1999. CC-chemokine receptor 6 is expressed on diverse memory subsets of T cells and determines responsiveness to macrophage inflammatory protein 3α. J. Immunol. 162:186.
22. Campbell, J. J., J. Hedrick, A. Zlotnik, M. A. Siani, D. A. Thompson, and E. C. Butcher. 1998. Chemokines and the arrest of lymphocytes rolling under flow conditions. Science 279:381.
23. Bolin, L. M., T. McNeil, L. A. Lucian, B. DeVaux, K. Franz-Bacon, D. M. Gorman, S. Zurawski, R. Murray, and T. K. McClanahan. 1997. HNMP-1: a novel hematopoietic and neural membrane protein differentially regulated in neural development and injury. J. Neurosci. 17:5493
24. Vicari, A. P., D. J. Figueroa, J. A. Hedrick, J. S. Foster, K. P. Singh, S. Menon, N. G. Copeland, D. J. Gilbert, N. A. Jenkins, K. B. Bacon, et al. 1997. TECK: a novel CC chemokine specifically expressed by thymic dendritic cells and potentially involved in T cell development. Immunity 7:291.
25. Detmar, M., L. F. Brown, K. P. Claffey, K. T. Yeo, O. Kocher, R. W. Jackman, B. Berse, and H. F. Dvorak. 1994. Overexpression of vascular permeability factor/vascular endothelial growth factor and its receptors in psoriasis. J. Exp. Med. 180:1141.
26. Boismenu, R., L. Feng, Y. Y. Xia, J. C. Chang, and W. L. Havran. 1996. Chemokine expression by intraepithelial γδ T cells: implications for the recruitment of inflammatory cells to damaged epithelia. J. Immunol. 157:985.
27. Caux, C., C. Massacrier, B. Vanbervliet, B. Dubois, C. Van Kooten, I. Durand, and J. Banchereau. 1994. Activation of human dendritic cells through CD40 cross-linking. J. Exp. Med. 180:1263.
28. Kulke, R., E. Bornscheuer, C. Schluter, J. Bartels, J. Rowert, M. Sticherling, and E. Christophers. 1998. The CXC receptor 2 is overexpressed in psoriatic epidermis. J. Invest. Dermatol. 110:90.
29. Schulz, B. S., G. Michel, S. Wagner, R. Suss, A. Beetz, R. U. Peter, L. Kemeny, and T. Ruzicka. 1993. Increased expression of epidermal IL-8 receptor in psoriasis: down-regulation by FK-506 in vitro. J. Immunol. 151:4399.
30. Valdimarsson, H., H. Sigmundsdottir, and I. Jonsdottir. 1997. Is psoriasis induced by streptococcal superantigens and maintained by M-protein-specific T cells that cross-react with keratin? Clin. Exp. Immunol. 107(Suppl. 1):21.
31. Nickoloff, B. J., R. S. Mitra, J. Green, X. G. Zheng, Y. Shimizu, C. Thompson, and L. A. Turka. 1993. Accessory cell function of keratinocytes for superantigens: dependence on lymphocyte function-associated antigen-1/intercellular adhesion molecule-1 interaction. J. Immunol. 150:2148.
32. Nickoloff, B. J., R. S. Mitra, J. Green, Y. Shimizu, C. Thompson, and L. A. Turka. 1993, Activated keratinocytes present bacterial-derived superantigens to T lymphocytes: relevance to psoriasis. J. Dermatol. Sci. 6:127.
33. Picker, L. J., L. W. Terstappen, L. S. Rott, P. R. Streeter, H. Stein, and E. C. Butcher. 1990. Differential expression of homing-associated adhesion molecules by T cell subsets in man. J. Immunol. 145:3247.
34. Isaacs, J. D., N. Burrows, M. Wing, M. T. Keogan, P. R. Rebello, R. A. Watts, R. J. Pye, P. Norris, B. L. Hazelman, G. Hale, et al. 1997. Humanized anti-CD4 monoclonal antibody therapy of autoimmune and inflammatory disease. Clin. Exp. Immunol. 110:158.
35. Thivolet, J., and J. F. Nicolas. 1994. Immunointervention in psoriasis with anti-CD4 antibodies. Int. J. Dermatol. 33:327.
36. Morel, P., J. P. Revillard, J. F. Nicolas, J. Wijdenes, H. Rizova, and J. Thivolet. 1992. Anti-CD4 monoclonal antibody therapy in severe psoriasis. J. Autoimmun. 5:465.
37. Gottlieb, A. B., A. D. Luster, D. N. Posnett, and D. M. Carter. 1988. Detection of a γ interferon-induced protein IP-10 in psoriatic plaques. J. Exp. Med. 168: 941.
38. Lemster, B. H., P. B. Carroll. H. R. Rilo, N. Johnson, A. Nikaein, and A. W. Thomson. 1995. IL-8/1L-8 receptor expression in psoriasis and the response to systemic tacrolimus (FK506) therapy. Clin. Exp. Immunol. 99:148.
39. Gillitzer, R., K. Wolff, D. Tong, C. Muller, T. Yoshimura, A. A. Hartmann, G. Stingl, and R. Berger. 1993. MCP-1 mRNA expression in basal keratinocytes of psoriatic lesions. J. Invest. Dermatol. 101:127.
40. Fukuoka, M., Y. Ogino, H. Sato, T. Ohta, K. Komoriya, K. Nishioka, and I. Katayama. 1998. RANTES expression in psoriatic skin, and regulation of RANTES and IL-8 production in cultured epidermal keratinocytes by active vitamin D3 (tacalcitol). Br. J. Dermatol. 138:63.
41. Goebeler, M., A. Toksoy, U. Spandau, E. Engelhardt, E. B. Brocker, and R. Gillitzer. 1998. The C-X-C chemokine Mig is highly expressed in the papillae of psoriatic lesions. J. Pathol. 184:89.
42. Davison, S., M. Allen, A. Harmer, R. Vaughan, and J. N. Barker. 1999. Increased T-cell receptor vβ2 chain expression in skin homing lymphocytes in psoriasis. Br. J. Dermatol. 140:845.
43. Terajima, S., M. Higaki, Y. Igarashi, T. Nogita, and M. Kawashima. 1998. An important role of tumor necrosis factor-α in the induction of adhesion molecules in psoriasis. Arch. Dermatol. Res. 290:246.
44. Mizutani, H., Y. Ohmoto, T. Mizutani, M. Murata, and M. Shimizu. 1997. Role of increased production of monocytes TNF-α, IL-1β and IL-6 in psoriasis: relation to focal infection, disease activity and responses to treatments. J. Dermatol. Sci. 14:145.
45. Debets, R., J. P. Hegmans, R. J. Troost, R. Benner, and E. P. Prens. 1995. Enhanced production of biologically active interleukin-1α and interleukin-1β by psoriatic epidermal cells ex vivo: evidence of increased cytosolic interleukin-1β levels and facilitated interleukin-1 release. Eur. J. Immunol. 25:1624.
46. Nickoloff, B. J., G. D. Karabin, J. N. Barker, C. E. Griffiths, V. Sarma, R. S. Mitra, J. T. Elder, S. L. Kunkel, and V. M. Dixit. 1991. Cellular localization of interleukin-8 and its inducer, tumor necrosis factor-α in psoriasis. Am. J. Pathol. 138:129.
47. Gomi, T., T. Shiohara, T. Munakata, K. Imanishi, and M. Nagashima. 1991. Interleukin 1α, tumor necrosis factor α, and interferon γ in psoriasis. Arch. Dermatol. 127:827.
48. Bos, J. D., H. J. Hulsebosch, S. R. Krieg, P. M. Bakker, and R. H. Cormane. 1983. Immunocompetent cells in psoriasis: in situ immunophenotyping by monoclonal antibodies. Arch. Dermatol. Res. 275:181.
49. +) in both normal and diseased human skin. Arch. Dermatol. Res. 281:24.
50. Teunissen, M. B., C. W. Koomen, R. de Waal Malefyt, E. A. Wierenga, and J. D. Bos. 1998. Interleukin-17 and interferon-γ synergize in the enhancement of proinflammalory cytokine production by human keratinocytes. J. Invest. Dermatol. 111:645.
51. Nestle, F. O., L. A. Turka, and B. J. Nickoloff. 1994. Characterization of dermal dendritic cells in psoriasis: autostimulation of T lymphocytes and induction of Th1 type cytokines. J. Clin. Invest. 94:202.
52. Charbonnier, A. S., N. Kohrgruber, E. Kriehuber, G. Stingl, A. Rot, and D. Maurer. 1999. Macrophage inflammatory protein 3α is involved in the constitutive trafficking of epidermal Langerhans cells. J. Exp. Med. 190:1755.
53. Tanaka, Y., T. Imai, M. Baba, I. Ishikawa, M. Uehira, H. Nomiyama, and O. Yoshie. 1999. Selective expression of liver and activation-regulated chemokine (LARC) in intestinal epithelium in mice and humans. Eur. J. Immunol. 29:633.
54. Raychaudhuri, S. P., W. Y. Jiang, E. M. Farber, T. J. Schall, M. R. Ruff, and C. B. Pert. 1999. Upregulation of RANTES in psoriatic keratinocytes: a possible pathogenic mechanism for psoriasis. Acta Dermato-Venereol. 79:9.
55. Deleuran, M., L. Buhl, T. Ellingsen, A. Harada, C. G. Larsen, K. Matsushima, and B. Deleuran. 1996. Localization of monocyte chemotactic and activating factor (MCAF/MCP-1) in psoriasis. J. Dermatol. Sci. 13:228.
56. Gillitzer, R., U. Ritter, U. Spandau, M. Goebeler, and E. B. Brocker. 1996. Differential expression of GRO-α and IL-8 mRNA in psoriasis: a model for neutrophil migration and accumulation in vivo. J. Invest. Dermatol. 107:778.
57. Gillitzer, R., R. Berger, V. Mielke, C. Muller, K. Wolff, and G. Stingl. 1991. Upper keratinocytes of psoriatic skin lesions express high levels of NAP-1/IL-8 mRNA in situ. J. Invest. Dermatol. 97:73.
58. Kulke, R., I. Todt-Pingel, D. Rademacher, J. Rowert, J. M. Schroder, and E. Christophers. 1996. Co-localized overexpression of GRO-α and IL-8 mRNA is restricted to the suprapapillary layers of psoriatic lesions. J. Invest. Dermatol. 106:526.
59. Yang, D., O. Chertov, S. N. Bykovskaia, Q. Chen, M. J. Buffo, J. Shogan, M. Anderson, J. M. Schroder, J. M. Wang, O. M. Howard, et al. 1999. β-Defensins: linking innate and adaptive immunity through dendritic and T cell CCR6. Science 286:525.
60. Campbell, J. J., G. Haraldsen, J. Pan, J. Rottman, S. Qin, P. Ponath, D. P. Andrew, R. Warnke, N. Ruffing, N. Kassam, et al. 1999. The chemokine receptor CCR4 in vascular recognition by cutaneous but not intestinal memory T cells. Nature 400:776.
61. Boorsma, D. M., J. Flier, S. Sampat, C. Ottevanger, P. de Haan, L. Hooft, R. Willemze, C. P. Tensen, and T. J. Stoof. 1998. Chemokine IP-10 expression in cultured human keratinocytes. Arch. Dermatol. Res. 290:335.