-
1
-
-
11444255268
-
On respiratory impairment in cancer cells
-
Warburg, O. On respiratory impairment in cancer cells. Science 1956, 124, 269-270.
-
(1956)
Science
, vol.124
, pp. 269-270
-
-
Warburg, O.1
-
2
-
-
12444279265
-
On the origin of cancer cells
-
Warburg, O. On the origin of cancer cells. Science, 1956, 123, 309-314.
-
(1956)
Science
, vol.123
, pp. 309-314
-
-
Warburg, O.1
-
3
-
-
0036189504
-
Variability in glucose transporter-1 levels and hexokinase activity in human melanoma
-
Wachsberger, P. R.; Gressen, E. L.; Bhala, A.; Bobyock, S. B.; Storck, C.; Coss, R. A.; Berd, D.; Leeper, D. B. Variability in glucose transporter-1 levels and hexokinase activity in human melanoma. Melanoma Res., 2002, 12, 35-43.
-
(2002)
Melanoma Res
, vol.12
, pp. 35-43
-
-
Wachsberger, P.R.1
Gressen, E.L.2
Bhala, A.3
Bobyock, S.B.4
Storck, C.5
Coss, R.A.6
Berd, D.7
Leeper, D.B.8
-
4
-
-
0033981463
-
Expression of the human erythrocyte glucose transporter in transitional cell carcinoma of the bladder
-
Chang, S.; Lee, S.; Lee, C.; Kim, J. I.; Kim, Y. Expression of the human erythrocyte glucose transporter in transitional cell carcinoma of the bladder. Urology, 2000, 55, 448-452.
-
(2000)
Urology
, vol.55
, pp. 448-452
-
-
Chang, S.1
Lee, S.2
Lee, C.3
Kim, J.I.4
Kim, Y.5
-
5
-
-
0034806134
-
Fatty acid synthase inhibition in human breast cancer cells leads to malonyl-CoA-induced inhibition of fatty acid oxidation and cytotoxicity
-
Thupari, J. N.; Pinn, M. L.; Kuhajda, F. P. Fatty acid synthase inhibition in human breast cancer cells leads to malonyl-CoA-induced inhibition of fatty acid oxidation and cytotoxicity. Biochem. Biophys. Res. Commun., 2001, 285, 217-223.
-
(2001)
Biochem. Biophys. Res. Commun
, vol.285
, pp. 217-223
-
-
Thupari, J.N.1
Pinn, M.L.2
Kuhajda, F.P.3
-
6
-
-
11444255268
-
On respiratory impairment in cancer cells
-
Weinhouse, S. On respiratory impairment in cancer cells. Science 1956, 124, 267-269.
-
(1956)
Science
, vol.124
, pp. 267-269
-
-
Weinhouse, S.1
-
7
-
-
0347694776
-
Cancer metabolism: Facts, fantasy, and fiction
-
Zu, X. L.; Guppy, M. Cancer metabolism: facts, fantasy, and fiction. Biochem. Biophys. Res. Commun., 2004, 313, 459-465.
-
(2004)
Biochem. Biophys. Res. Commun
, vol.313
, pp. 459-465
-
-
Zu, X.L.1
Guppy, M.2
-
8
-
-
0042575733
-
High aerobic glycolysis of rat hepatoma cells in culture: Role of mitochondrial hexokinase
-
Bustamante, E.; Pedersen, P. L. High aerobic glycolysis of rat hepatoma cells in culture: role of mitochondrial hexokinase. Proc. Natl. Acad. Sci. USA, 1977, 74, 3735-3739.
-
(1977)
Proc. Natl. Acad. Sci. USA
, vol.74
, pp. 3735-3739
-
-
Bustamante, E.1
Pedersen, P.L.2
-
9
-
-
33746924468
-
Hexokinase II: Cancer's double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondria
-
Mathupala, S. P.; Ko, Y. H.; Pedersen, P. L. Hexokinase II: cancer's double-edged sword acting as both facilitator and gatekeeper of malignancy when bound to mitochondria. Oncogene, 2006, 25, 4777-4786.
-
(2006)
Oncogene
, vol.25
, pp. 4777-4786
-
-
Mathupala, S.P.1
Ko, Y.H.2
Pedersen, P.L.3
-
10
-
-
0028149343
-
Differences in expression and intracellular distribution of hexokinase isoenzymes in rat liver cells of different transformation stages
-
Rempel, A.; Bannasch, P.; Mayer, D. Differences in expression and intracellular distribution of hexokinase isoenzymes in rat liver cells of different transformation stages. Biochim. Biophys. Acta, 1994, 1219, 660-668.
-
(1994)
Biochim. Biophys. Acta
, vol.1219
, pp. 660-668
-
-
Rempel, A.1
Bannasch, P.2
Mayer, D.3
-
11
-
-
0031057368
-
Hexokinase expression in liver preneoplasia and neoplasia
-
Mayer, D.; Klimek, F.; Rempel, A.; Bannasch, P. Hexokinase expression in liver preneoplasia and neoplasia. Biochem. Soc. Trans., 1997, 25, 122-127.
-
(1997)
Biochem. Soc. Trans
, vol.25
, pp. 122-127
-
-
Mayer, D.1
Klimek, F.2
Rempel, A.3
Bannasch, P.4
-
12
-
-
0037056002
-
Mitochondrial bound type II hexokinase: A key player in the growth and survival of many cancers and an ideal prospect for therapeutic intervention
-
Pedersen, P. L.; Mathupala, S.; Rempel, A.; Geschwind, J. F.; Ko, Y. H. Mitochondrial bound type II hexokinase: a key player in the growth and survival of many cancers and an ideal prospect for therapeutic intervention. Biochim. Biophys. Acta, 2002, 1555, 14-20.
-
(2002)
Biochim. Biophys. Acta
, vol.1555
, pp. 14-20
-
-
Pedersen, P.L.1
Mathupala, S.2
Rempel, A.3
Geschwind, J.F.4
Ko, Y.H.5
-
14
-
-
0038714272
-
Isozymes of mammalian hexokinase: Structure, subcellular localization and metabolic function
-
Wilson, J. E. Isozymes of mammalian hexokinase: structure, subcellular localization and metabolic function. J. Exp. Biol., 2003, 206, 2049-2057.
-
(2003)
J. Exp. Biol
, vol.206
, pp. 2049-2057
-
-
Wilson, J.E.1
-
15
-
-
0038012340
-
Glucose metabolism in cancer. Evidence that demethylation events play a role in activating type II hexokinase gene expression
-
Goel, A.; Mathupala, S. P.; Pedersen, P. L. Glucose metabolism in cancer. Evidence that demethylation events play a role in activating type II hexokinase gene expression. J. Biol. Chem., 2003, 278, 15333-15340.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 15333-15340
-
-
Goel, A.1
Mathupala, S.P.2
Pedersen, P.L.3
-
16
-
-
0029891049
-
Glucose catabolism in cancer cells: Amplification of the gene encoding type II hexokinase
-
Rempel, A.; Mathupala, S. P.; Griffin, C. A.; Hawkins, A. L.; Pedersen, P. L. Glucose catabolism in cancer cells: amplification of the gene encoding type II hexokinase. Cancer Res., 1996, 56, 2468-2471.
-
(1996)
Cancer Res
, vol.56
, pp. 2468-2471
-
-
Rempel, A.1
Mathupala, S.P.2
Griffin, C.A.3
Hawkins, A.L.4
Pedersen, P.L.5
-
17
-
-
0022339591
-
Evidence that transcription of the hexokinase gene is increased in a rapidly growing rat hepatoma
-
Johansson, T.; Berrez, J. M.; Nelson, B. D. Evidence that transcription of the hexokinase gene is increased in a rapidly growing rat hepatoma. Biochem. Biophys. Res. Commun., 1985, 133, 608-613.
-
(1985)
Biochem. Biophys. Res. Commun
, vol.133
, pp. 608-613
-
-
Johansson, T.1
Berrez, J.M.2
Nelson, B.D.3
-
18
-
-
0028093098
-
Microheterogeneity of cytosolic and membrane-bound hexokinase II in Morris hepatoma 3924A
-
Rempel, A.; Bannasch, P.; Mayer, D. Microheterogeneity of cytosolic and membrane-bound hexokinase II in Morris hepatoma 3924A. Biochem. J., 1994, 303, 269-274.
-
(1994)
Biochem. J
, vol.303
, pp. 269-274
-
-
Rempel, A.1
Bannasch, P.2
Mayer, D.3
-
19
-
-
0029063507
-
Glucose catabolism in cancer cells. Isolation, sequence, and activity of the promoter for type II hexokinase
-
Mathupala, S. P.; Rempel, A.; Pedersen, P. L. Glucose catabolism in cancer cells. Isolation, sequence, and activity of the promoter for type II hexokinase. J. Biol. Chem., 1995, 270, 16918-16925.
-
(1995)
J. Biol. Chem
, vol.270
, pp. 16918-16925
-
-
Mathupala, S.P.1
Rempel, A.2
Pedersen, P.L.3
-
20
-
-
0022595453
-
Hexokinase receptor complex in hepatoma mitochondria: Evidence from N,N′-dicyclohexylcarbodiimide-labeling studies for the involvement of the pore-forming protein VDAC
-
Nakashima, R. A.; Mangan, P. S.; Colombini, M.; Pedersen, P. L. Hexokinase receptor complex in hepatoma mitochondria: evidence from N,N′-dicyclohexylcarbodiimide-labeling studies for the involvement of the pore-forming protein VDAC. Biochemistry, 1986, 25, 1015-1021.
-
(1986)
Biochemistry
, vol.25
, pp. 1015-1021
-
-
Nakashima, R.A.1
Mangan, P.S.2
Colombini, M.3
Pedersen, P.L.4
-
21
-
-
0024237766
-
Functional significance of mitochondrial bound hexokinase in tumor cell metabolism. Evidence for preferential phosphorylation of glucose by intramitochondrially generated ATP
-
Arora, K. K.; Pedersen, P. L. Functional significance of mitochondrial bound hexokinase in tumor cell metabolism. Evidence for preferential phosphorylation of glucose by intramitochondrially generated ATP. J. Biol. Chem., 1988, 263, 17422-17428.
-
(1988)
J. Biol. Chem
, vol.263
, pp. 17422-17428
-
-
Arora, K.K.1
Pedersen, P.L.2
-
22
-
-
0041309460
-
Hexokinase II: The integration of energy metabolism and control of apoptosis
-
Pastorino, J. G.; Hoek, J. B. Hexokinase II: the integration of energy metabolism and control of apoptosis. Curr. Med. Chem., 2003, 10, 1535-1551.
-
(2003)
Curr. Med. Chem
, vol.10
, pp. 1535-1551
-
-
Pastorino, J.G.1
Hoek, J.B.2
-
23
-
-
0042381676
-
The function of complexes between the outer mitochondrial membrane pore (VDAC) and the adenine nucleotide translocase in regulation of energy metabolism and apoptosis
-
Vyssokikh, M. Y.; Brdiczka, D. The function of complexes between the outer mitochondrial membrane pore (VDAC) and the adenine nucleotide translocase in regulation of energy metabolism and apoptosis. Acta Biochim. Pol., 2003, 50, 389-404.
-
(2003)
Acta Biochim. Pol
, vol.50
, pp. 389-404
-
-
Vyssokikh, M.Y.1
Brdiczka, D.2
-
24
-
-
21744441655
-
The voltage-dependent anion channel-1 modulates apoptotic cell death
-
Zaid, H.; Abu-Hamad, S.; Israelson, A.; Nathan, I.; Shoshan-Barmatz, V. The voltage-dependent anion channel-1 modulates apoptotic cell death. Cell Death Differ., 2005, 12, 751-760.
-
(2005)
Cell Death Differ
, vol.12
, pp. 751-760
-
-
Zaid, H.1
Abu-Hamad, S.2
Israelson, A.3
Nathan, I.4
Shoshan-Barmatz, V.5
-
25
-
-
35448996809
-
Actuality of Warburg's views in our understanding of renal cancer metabolism
-
Godinot, C.; de Laplanche, E.; Hervouet, E.; Simonnet, H. Actuality of Warburg's views in our understanding of renal cancer metabolism. J. Bioenerg. Biomembr., 2007, 39, 235-241.
-
(2007)
J. Bioenerg. Biomembr
, vol.39
, pp. 235-241
-
-
Godinot, C.1
de Laplanche, E.2
Hervouet, E.3
Simonnet, H.4
-
26
-
-
0025863170
-
Clustering of features of von Hippel-Lindau syndrome: Evidence for a complex genetic locus
-
Neumann, H. P.; Wiestler, O. D. Clustering of features of von Hippel-Lindau syndrome: evidence for a complex genetic locus. Lancet, 1991, 337, 1052-1054.
-
(1991)
Lancet
, vol.337
, pp. 1052-1054
-
-
Neumann, H.P.1
Wiestler, O.D.2
-
27
-
-
0029074707
-
Von Hippel-Lindau (VHL) disease with pheochromocytoma in the Black Forest region of Germany: Evidence for a founder effect
-
Brauch, H.; Kishida, T.; Glavac, D.; Chen, F.; Pausch, F.; Hofler, H.; Latif, F.; Lerman, M. I.; Zbar, B.; Neumann, H. P. Von Hippel-Lindau (VHL) disease with pheochromocytoma in the Black Forest region of Germany: evidence for a founder effect. Hum. Genet., 1995, 95, 551-556.
-
(1995)
Hum. Genet
, vol.95
, pp. 551-556
-
-
Brauch, H.1
Kishida, T.2
Glavac, D.3
Chen, F.4
Pausch, F.5
Hofler, H.6
Latif, F.7
Lerman, M.I.8
Zbar, B.9
Neumann, H.P.10
-
28
-
-
0034602950
-
Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma
-
Baysal, B. E.; Ferrell, R. E.; Willett-Brozick, J. E.; Lawrence, E. C.; Myssiorek, D.; Bosch, A.; van der Mey, A.; Taschner, P. E.; Rubinstein, W. S.; Myers, E. N.; Richard, C. W., 3rd; Cornelisse, C. J.; Devilee, P.; Devlin, B. Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma. Science, 2000, 287, 848-851.
-
(2000)
Science
, vol.287
, pp. 848-851
-
-
Baysal, B.E.1
Ferrell, R.E.2
Willett-Brozick, J.E.3
Lawrence, E.C.4
Myssiorek, D.5
Bosch, A.6
van der Mey, A.7
Taschner, P.E.8
Rubinstein, W.S.9
Myers, E.N.10
Richard 3rd, C.W.11
Cornelisse, C.J.12
Devilee, P.13
Devlin, B.14
-
29
-
-
0028053910
-
Carotid body chemoreceptors: From natural stimuli to sensory discharges
-
Gonzalez, C.; Almaraz, L.; Obeso, A.; Rigual, R. Carotid body chemoreceptors: from natural stimuli to sensory discharges. Physiol. Rev., 1994, 74, 829-898.
-
(1994)
Physiol. Rev
, vol.74
, pp. 829-898
-
-
Gonzalez, C.1
Almaraz, L.2
Obeso, A.3
Rigual, R.4
-
30
-
-
0033529656
-
Perspectives on oxygen sensing
-
Semenza, G. L. Perspectives on oxygen sensing. Cell 1999, 98, 281-284.
-
(1999)
Cell
, vol.98
, pp. 281-284
-
-
Semenza, G.L.1
-
31
-
-
0029842459
-
Oxygen sensing and molecular adaptation to hypoxia
-
Bunn, H. F.; Poyton, R. O. Oxygen sensing and molecular adaptation to hypoxia. Physiol. Rev., 1996, 76, 839-885.
-
(1996)
Physiol. Rev
, vol.76
, pp. 839-885
-
-
Bunn, H.F.1
Poyton, R.O.2
-
32
-
-
0017209477
-
Chronic hypoxia and chemodectomas in bovines at high altitudes
-
Arias-Stella, J.; Bustos, F. Chronic hypoxia and chemodectomas in bovines at high altitudes. Arch Pathol. Lab. Med., 1976, 100, 636-639.
-
(1976)
Arch Pathol. Lab. Med
, vol.100
, pp. 636-639
-
-
Arias-Stella, J.1
Bustos, F.2
-
33
-
-
0017179154
-
Chief cell hyperplasia in the human carotid body at high altitudes; physiologic and pathologic significance
-
Arias-Stella, J.; Valcarcel, J. Chief cell hyperplasia in the human carotid body at high altitudes; physiologic and pathologic significance. Hum. Pathol., 1976, 7, 361-373.
-
(1976)
Hum. Pathol
, vol.7
, pp. 361-373
-
-
Arias-Stella, J.1
Valcarcel, J.2
-
34
-
-
0015103221
-
The carotid body in animals at high altitude
-
Edwards, C.; Heath, D.; Harris, P.; Castillo, Y.; Kruger, H.; Arias-Stella, J. The carotid body in animals at high altitude. J. Pathol., 1971, 104, 231-238.
-
(1971)
J. Pathol
, vol.104
, pp. 231-238
-
-
Edwards, C.1
Heath, D.2
Harris, P.3
Castillo, Y.4
Kruger, H.5
Arias-Stella, J.6
-
35
-
-
0015793061
-
High altitude hypoxia and chemodectomas
-
Saldana, M. J.; Salem, L. E.; Travezan, R. High altitude hypoxia and chemodectomas. Hum. Pathol., 1973, 4 (2), 251-263.
-
(1973)
Hum. Pathol
, vol.4
, Issue.2
, pp. 251-263
-
-
Saldana, M.J.1
Salem, L.E.2
Travezan, R.3
-
36
-
-
0031569815
-
Role of basic FGF and oxygen in control of proliferation, survival, and neuronal differentiation in carotid body chromaffin cells
-
Nurse, C. A.; Vollmer, C. Role of basic FGF and oxygen in control of proliferation, survival, and neuronal differentiation in carotid body chromaffin cells. Dev. Biol., 1997, 184, 197-206.
-
(1997)
Dev. Biol
, vol.184
, pp. 197-206
-
-
Nurse, C.A.1
Vollmer, C.2
-
37
-
-
0018375375
-
Paragangliomas of the head and neck region. A pathologic study of tumors from 71 patients
-
Lack, E. E.; Cubilla, A. L.; Woodruff, J. M. Paragangliomas of the head and neck region. A pathologic study of tumors from 71 patients. Hum. Pathol., 1979, 10, 191-218.
-
(1979)
Hum. Pathol
, vol.10
, pp. 191-218
-
-
Lack, E.E.1
Cubilla, A.L.2
Woodruff, J.M.3
-
38
-
-
0021885506
-
Carotid body hyperplasia in cystic fibrosis and cyanotic heart disease. A combined morphometric, ultrastructural, and biochemical study
-
Lack, E. E.; Perez-Atayde, A. R.; Young, J. B. Carotid body hyperplasia in cystic fibrosis and cyanotic heart disease. A combined morphometric, ultrastructural, and biochemical study. Am. J. Pathol., 1985, 119, 301-314.
-
(1985)
Am. J. Pathol
, vol.119
, pp. 301-314
-
-
Lack, E.E.1
Perez-Atayde, A.R.2
Young, J.B.3
-
39
-
-
0016627997
-
Jugular body tumors: Hyperplasias or true neoplasms? Light and electron microscopical investigations
-
Stiller, D.; Katenkamp, D.; Kuttner, K. Jugular body tumors: hyperplasias or true neoplasms? Light and electron microscopical investigations. Virchows Arch. A Pathol. Anat. Histol., 1975, 365, 163-177.
-
(1975)
Virchows Arch. A Pathol. Anat. Histol
, vol.365
, pp. 163-177
-
-
Stiller, D.1
Katenkamp, D.2
Kuttner, K.3
-
40
-
-
27744606274
-
Mitochondrial succinate is instrumental for HIF1alpha nuclear translocation in SDHA-mutant fibroblasts under normoxic conditions
-
Briere, J. J.; Favier, J.; Benit, P.; El Ghouzzi, V.; Lorenzato, A.; Rabier, D.; Di Renzo, M. F.; Gimenez-Roqueplo, A. P.; Rustin, P. Mitochondrial succinate is instrumental for HIF1alpha nuclear translocation in SDHA-mutant fibroblasts under normoxic conditions. Hum. Mol. Genet., 2005, 14 (21), 3263-3269.
-
(2005)
Hum. Mol. Genet
, vol.14
, Issue.21
, pp. 3263-3269
-
-
Briere, J.J.1
Favier, J.2
Benit, P.3
El Ghouzzi, V.4
Lorenzato, A.5
Rabier, D.6
Di Renzo, M.F.7
Gimenez-Roqueplo, A.P.8
Rustin, P.9
-
41
-
-
11244279161
-
A mutation in the SDHC gene of complex II increases oxidative stress, resulting in apoptosis and tumorigenesis
-
Ishii, T.; Yasuda, K.; Akatsuka, A.; Hino, O.; Hartman, P. S.; Ishii, N. A mutation in the SDHC gene of complex II increases oxidative stress, resulting in apoptosis and tumorigenesis. Cancer Res., 2005, 65, 203-209.
-
(2005)
Cancer Res
, vol.65
, pp. 203-209
-
-
Ishii, T.1
Yasuda, K.2
Akatsuka, A.3
Hino, O.4
Hartman, P.S.5
Ishii, N.6
-
42
-
-
33747893489
-
Mutation of succinate dehydrogenase subunit C results in increased O2.-, oxidative stress, and genomic instability
-
Slane, B. G.; Aykin-Burns, N.; Smith, B. J.; Kalen, A. L.; Goswami, P. C.; Domann, F. E.; Spitz, D. R. Mutation of succinate dehydrogenase subunit C results in increased O2.-, oxidative stress, and genomic instability. Cancer Res., 2006, 66, 7615-7620.
-
(2006)
Cancer Res
, vol.66
, pp. 7615-7620
-
-
Slane, B.G.1
Aykin-Burns, N.2
Smith, B.J.3
Kalen, A.L.4
Goswami, P.C.5
Domann, F.E.6
Spitz, D.R.7
-
43
-
-
0033767445
-
Mutations in SDHC cause autosomal dominant paraganglioma, type 3
-
Niemann, S.; Muller, U. Mutations in SDHC cause autosomal dominant paraganglioma, type 3. Nat. Genet., 2000, 26, 268-270.
-
(2000)
Nat. Genet
, vol.26
, pp. 268-270
-
-
Niemann, S.1
Muller, U.2
-
44
-
-
18344381765
-
Prevalence of SDHB, SDHC, and SDHD germline mutations in clinic patients with head and neck paragangliomas
-
Baysal, B. E.; Willett-Brozick, J. E.; Lawrence, E. C.; Drovdlic, C. M.; Savul, S. A.; McLeod, D. R.; Yee, H. A.; Brackmann, D. E.; Slattery, W. H., 3rd; Myers, E. N.; Ferrell, R. E.; Rubinstein, W. S. Prevalence of SDHB, SDHC, and SDHD germline mutations in clinic patients with head and neck paragangliomas. J. Med. Genet., 2002, 39, 178-183.
-
(2002)
J. Med. Genet
, vol.39
, pp. 178-183
-
-
Baysal, B.E.1
Willett-Brozick, J.E.2
Lawrence, E.C.3
Drovdlic, C.M.4
Savul, S.A.5
McLeod, D.R.6
Yee, H.A.7
Brackmann, D.E.8
Slattery 3rd, W.H.9
Myers, E.N.10
Ferrell, R.E.11
Rubinstein, W.S.12
-
45
-
-
0034964421
-
Gene mutations in the succinate dehydrogenase subunit SDHB cause susceptibility to familial pheochromocytoma and to familial paraganglioma
-
Astuti, D.; Latif, F.; Dallol, A.; Dahia, P. L.; Douglas, F.; George, E.; Skoldberg, F.; Husebye, E. S.; Eng, C.; Maher, E. R. Gene mutations in the succinate dehydrogenase subunit SDHB cause susceptibility to familial pheochromocytoma and to familial paraganglioma. Am. J. Hum. Genet., 2001, 69, 49-54.
-
(2001)
Am. J. Hum. Genet
, vol.69
, pp. 49-54
-
-
Astuti, D.1
Latif, F.2
Dallol, A.3
Dahia, P.L.4
Douglas, F.5
George, E.6
Skoldberg, F.7
Husebye, E.S.8
Eng, C.9
Maher, E.R.10
-
46
-
-
9144249602
-
Early-onset renal cell carcinoma as a novel extraparaganglial component of SDHB-associated heritable paraganglioma
-
Vanharanta, S.; Buchta, M.; McWhinney, S. R.; Virta, S. K.; Peczkowska, M.; Morrison, C. D.; Lehtonen, R.; Januszewicz, A.; Jarvinen, H.; Juhola, M.; Mecklin, J. P.; Pukkala, E.; Herva, R.; Kiuru, M.; Nupponen, N. N.; Aaltonen, L. A.; Neumann, H. P.; Eng, C. Early-onset renal cell carcinoma as a novel extraparaganglial component of SDHB-associated heritable paraganglioma. Am. J. Hum. Genet., 2004, 74, 153-159.
-
(2004)
Am. J. Hum. Genet
, vol.74
, pp. 153-159
-
-
Vanharanta, S.1
Buchta, M.2
McWhinney, S.R.3
Virta, S.K.4
Peczkowska, M.5
Morrison, C.D.6
Lehtonen, R.7
Januszewicz, A.8
Jarvinen, H.9
Juhola, M.10
Mecklin, J.P.11
Pukkala, E.12
Herva, R.13
Kiuru, M.14
Nupponen, N.N.15
Aaltonen, L.A.16
Neumann, H.P.17
Eng, C.18
-
47
-
-
51749113159
-
Germline SDHB mutations and familial renal cell carcinoma
-
Ricketts, C.; Woodward, E. R.; Killick, P.; Morris, M. R.; Astuti, D.; Latif, F.; Maher, E. R. Germline SDHB mutations and familial renal cell carcinoma. J. Natl. Cancer Inst., 2008, 100, 1260-2.
-
(2008)
J. Natl. Cancer Inst
, vol.100
, pp. 1260-1262
-
-
Ricketts, C.1
Woodward, E.R.2
Killick, P.3
Morris, M.R.4
Astuti, D.5
Latif, F.6
Maher, E.R.7
-
48
-
-
48249113935
-
Germline mutations and variants in the succinate dehydrogenase genes in Cowden and Cowden-like syndromes
-
Ni, Y.; Zbuk, K. M.; Sadler, T.; Patocs, A.; Lobo, G.; Edelman, E.; Platzer, P.; Orloff, M. S.; Waite, K. A.; Eng, C. Germline mutations and variants in the succinate dehydrogenase genes in Cowden and Cowden-like syndromes. Am. J. Hum. Genet., 2008, 83, 261-268.
-
(2008)
Am. J. Hum. Genet
, vol.83
, pp. 261-268
-
-
Ni, Y.1
Zbuk, K.M.2
Sadler, T.3
Patocs, A.4
Lobo, G.5
Edelman, E.6
Platzer, P.7
Orloff, M.S.8
Waite, K.A.9
Eng, C.10
-
49
-
-
0025261176
-
Fumarase deficiency is an autosomal recessive encephalopathy affecting both the mitochondrial and the cytosolic enzymes
-
Gellera, C.; Uziel, G.; Rimoldi, M.; Zeviani, M.; Laverda, A.; Carrara, F.; DiDonato, S. Fumarase deficiency is an autosomal recessive encephalopathy affecting both the mitochondrial and the cytosolic enzymes. Neurology, 1990, 40, 495-499.
-
(1990)
Neurology
, vol.40
, pp. 495-499
-
-
Gellera, C.1
Uziel, G.2
Rimoldi, M.3
Zeviani, M.4
Laverda, A.5
Carrara, F.6
DiDonato, S.7
-
50
-
-
0026778382
-
-
Liochev, S. I.; Fridovich, I., Fumarase C, the stable fumarase of Escherichia coli, is controlled by the soxRS regulon. Proc. Natl. Acad. Sci. USA, 1992, 89, 5892-5896.
-
Liochev, S. I.; Fridovich, I., Fumarase C, the stable fumarase of Escherichia coli, is controlled by the soxRS regulon. Proc. Natl. Acad. Sci. USA, 1992, 89, 5892-5896.
-
-
-
-
51
-
-
0028246154
-
Mutation of the fumarase gene in two siblings with progressive encephalopathy and fumarase deficiency
-
Bourgeron, T.; Chretien, D.; Poggi-Bach, J.; Doonan, S.; Rabier, D.; Letouze, P.; Munnich, A.; Rotig, A.; Landrieu, P.; Rustin, P. Mutation of the fumarase gene in two siblings with progressive encephalopathy and fumarase deficiency. J. Clin. Invest., 1994, 93, 2514-2518.
-
(1994)
J. Clin. Invest
, vol.93
, pp. 2514-2518
-
-
Bourgeron, T.1
Chretien, D.2
Poggi-Bach, J.3
Doonan, S.4
Rabier, D.5
Letouze, P.6
Munnich, A.7
Rotig, A.8
Landrieu, P.9
Rustin, P.10
-
52
-
-
0030938063
-
Mutations of fumarase that distinguish between the active site and a nearby dicarboxylic acid binding site
-
Weaver, T.; Lees, M.; Banaszak, L. Mutations of fumarase that distinguish between the active site and a nearby dicarboxylic acid binding site. Protein Sci., 1997, 6, 834-42.
-
(1997)
Protein Sci
, vol.6
, pp. 834-842
-
-
Weaver, T.1
Lees, M.2
Banaszak, L.3
-
53
-
-
18544365990
-
-
Tomlinson, I. P.; Alam, N. A.; Rowan, A. J.; Barclay, E.; Jaeger, E. E.; Kelsell, D.; Leigh, I.; Gorman, P.; Lamlum, H.; Rahman, S.; Roylance, R. R.; Olpin, S.; Bevan, S.; Barker, K.; Hearle, N.; Houlston, R. S.; Kiuru, M.; Lehtonen, R.; Karhu, A.; Vilkki, S.; Laiho, P.; Eklund, C.; Vierimaa, O.; Aittomaki, K.; Hietala, M.; Sistonen, P.; Paetau, A.; Salovaara, R.; Herva, R.; Launonen, V.; Aaltonen, L. A. Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer. Nat. Genet., 2002, 30, 406-410.
-
Tomlinson, I. P.; Alam, N. A.; Rowan, A. J.; Barclay, E.; Jaeger, E. E.; Kelsell, D.; Leigh, I.; Gorman, P.; Lamlum, H.; Rahman, S.; Roylance, R. R.; Olpin, S.; Bevan, S.; Barker, K.; Hearle, N.; Houlston, R. S.; Kiuru, M.; Lehtonen, R.; Karhu, A.; Vilkki, S.; Laiho, P.; Eklund, C.; Vierimaa, O.; Aittomaki, K.; Hietala, M.; Sistonen, P.; Paetau, A.; Salovaara, R.; Herva, R.; Launonen, V.; Aaltonen, L. A. Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer. Nat. Genet., 2002, 30, 406-410.
-
-
-
-
54
-
-
1542469716
-
Biallelic inactivation of fumarate hydratase (FH) occurs in nonsyndromic uterine leiomyomas but is rare in other tumors
-
Lehtonen, R.; Kiuru, M.; Vanharanta, S.; Sjoberg, J.; Aaltonen, L. M.; Aittomaki, K.; Arola, J.; Butzow, R.; Eng, C.; Husgafvel-Pursiainen, K.; Isola, J.; Jarvinen, H.; Koivisto, P.; Mecklin, J. P.; Peltomaki, P.; Salovaara, R.; Wasenius, V. M.; Karhu, A.; Launonen, V.; Nupponen, N. N.; Aaltonen, L. A. Biallelic inactivation of fumarate hydratase (FH) occurs in nonsyndromic uterine leiomyomas but is rare in other tumors. Am. J. Pathol., 2004, 164, 17-22.
-
(2004)
Am. J. Pathol
, vol.164
, pp. 17-22
-
-
Lehtonen, R.1
Kiuru, M.2
Vanharanta, S.3
Sjoberg, J.4
Aaltonen, L.M.5
Aittomaki, K.6
Arola, J.7
Butzow, R.8
Eng, C.9
Husgafvel-Pursiainen, K.10
Isola, J.11
Jarvinen, H.12
Koivisto, P.13
Mecklin, J.P.14
Peltomaki, P.15
Salovaara, R.16
Wasenius, V.M.17
Karhu, A.18
Launonen, V.19
Nupponen, N.N.20
Aaltonen, L.A.21
more..
-
55
-
-
13344270899
-
-
Campuzano, V.; Montermini, L.; Molto, M. D.; Pianese, L.; Cossee, M.; Cavalcanti, F.; Monros, E.; Rodius, F.; Duclos, F.; Monticelli, A.; Zara, F.; Canizares, J.; Koutnikova, H.; Bidichandani, S. I.; Gellera, C.; Brice, A.; Trouillas, P.; De Michele, G.; Filla, A.; De Frutos, R.; Palau, F.; Patel, P. I.; Di Donato, S.; Mandel, J. L.; Cocozza, S.; Koenig, M.; Pandolfo, M. Friedreich's ataxia: autosomal recessive disease caused by an intronic GAA triplet repeat expansion. Science 1996, 271, 1423-1427.
-
Campuzano, V.; Montermini, L.; Molto, M. D.; Pianese, L.; Cossee, M.; Cavalcanti, F.; Monros, E.; Rodius, F.; Duclos, F.; Monticelli, A.; Zara, F.; Canizares, J.; Koutnikova, H.; Bidichandani, S. I.; Gellera, C.; Brice, A.; Trouillas, P.; De Michele, G.; Filla, A.; De Frutos, R.; Palau, F.; Patel, P. I.; Di Donato, S.; Mandel, J. L.; Cocozza, S.; Koenig, M.; Pandolfo, M. Friedreich's ataxia: autosomal recessive disease caused by an intronic GAA triplet repeat expansion. Science 1996, 271, 1423-1427.
-
-
-
-
56
-
-
14744294785
-
Iron-sulfur-protein biogenesis in eukaryotes
-
Lill, R.; Muhlenhoff, U. Iron-sulfur-protein biogenesis in eukaryotes. Trends Biochem. Sci., 2005, 30, 133-141.
-
(2005)
Trends Biochem. Sci
, vol.30
, pp. 133-141
-
-
Lill, R.1
Muhlenhoff, U.2
-
57
-
-
0031253821
-
Aconitase and mitochondrial iron-sulphur protein deficiency in Friedreich ataxia
-
Rotig, A.; de Lonlay, P.; Chretien, D.; Foury, F.; Koenig, M.; Sidi, D.; Munnich, A.; Rustin, P. Aconitase and mitochondrial iron-sulphur protein deficiency in Friedreich ataxia. Nat. Genet., 1997, 17, 215-7.
-
(1997)
Nat. Genet
, vol.17
, pp. 215-217
-
-
Rotig, A.1
de Lonlay, P.2
Chretien, D.3
Foury, F.4
Koenig, M.5
Sidi, D.6
Munnich, A.7
Rustin, P.8
-
58
-
-
0037101845
-
The yeast frataxin homolog Yfh1p plays a specific role in the maturation of cellular Fe/S proteins
-
Muhlenhoff, U.; Richhardt, N.; Ristow, M.; Kispal, G.; Lill, R. The yeast frataxin homolog Yfh1p plays a specific role in the maturation of cellular Fe/S proteins. Hum. Mol. Genet., 2002, 11, 2025-2036.
-
(2002)
Hum. Mol. Genet
, vol.11
, pp. 2025-2036
-
-
Muhlenhoff, U.1
Richhardt, N.2
Ristow, M.3
Kispal, G.4
Lill, R.5
-
59
-
-
0035138072
-
Mouse models for Friedreich ataxia exhibit cardiomyopathy, sensory nerve defect and Fe-S enzyme deficiency followed by intramitochondrial iron deposits
-
Puccio, H.; Simon, D.; Cossee, M.; Criqui-Filipe, P.; Tiziano, F.; Melki, J.; Hindelang, C.; Matyas, R.; Rustin, P.; Koenig, M. Mouse models for Friedreich ataxia exhibit cardiomyopathy, sensory nerve defect and Fe-S enzyme deficiency followed by intramitochondrial iron deposits. Nat. Genet., 2001, 27, 181-186.
-
(2001)
Nat. Genet
, vol.27
, pp. 181-186
-
-
Puccio, H.1
Simon, D.2
Cossee, M.3
Criqui-Filipe, P.4
Tiziano, F.5
Melki, J.6
Hindelang, C.7
Matyas, R.8
Rustin, P.9
Koenig, M.10
-
60
-
-
0036537486
-
Frataxin promotes antioxidant defense in a thiol-dependent manner resulting in diminished malignant transformation in vitro
-
Shoichet, S. A.; Baumer, A. T.; Stamenkovic, D.; Sauer, H.; Pfeiffer, A. F.; Kahn, C. R.; Muller-Wieland, D.; Richter, C.; Ristow, M. Frataxin promotes antioxidant defense in a thiol-dependent manner resulting in diminished malignant transformation in vitro. Hum. Mol. Genet., 2002, 11, 815-21.
-
(2002)
Hum. Mol. Genet
, vol.11
, pp. 815-821
-
-
Shoichet, S.A.1
Baumer, A.T.2
Stamenkovic, D.3
Sauer, H.4
Pfeiffer, A.F.5
Kahn, C.R.6
Muller-Wieland, D.7
Richter, C.8
Ristow, M.9
-
61
-
-
33644868755
-
Induction of oxidative metabolism by mitochondrial frataxin inhibits cancer growth: Otto Warburg revisited
-
Schulz, T. J.; Thierbach, R.; Voigt, A.; Drewes, G.; Mietzner, B.; Steinberg, P.; Pfeiffer, A. F.; Ristow, M. Induction of oxidative metabolism by mitochondrial frataxin inhibits cancer growth: Otto Warburg revisited. J. Biol. Chem., 2006, 281, 977-981.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 977-981
-
-
Schulz, T.J.1
Thierbach, R.2
Voigt, A.3
Drewes, G.4
Mietzner, B.5
Steinberg, P.6
Pfeiffer, A.F.7
Ristow, M.8
-
62
-
-
29644448054
-
Targeted disruption of hepatic frataxin expression causes impaired mitochondrial function, decreased life span and tumor growth in mice
-
Thierbach, R.; Schulz, T. J.; Isken, F.; Voigt, A.; Mietzner, B.; Drewes, G.; von Kleist-Retzow, J. C.; Wiesner, R. J.; Magnuson, M. A.; Puccio, H.; Pfeiffer, A. F.; Steinberg, P.; Ristow, M. Targeted disruption of hepatic frataxin expression causes impaired mitochondrial function, decreased life span and tumor growth in mice. Hum. Mol. Genet., 2005, 14, 3857-3864.
-
(2005)
Hum. Mol. Genet
, vol.14
, pp. 3857-3864
-
-
Thierbach, R.1
Schulz, T.J.2
Isken, F.3
Voigt, A.4
Mietzner, B.5
Drewes, G.6
von Kleist-Retzow, J.C.7
Wiesner, R.J.8
Magnuson, M.A.9
Puccio, H.10
Pfeiffer, A.F.11
Steinberg, P.12
Ristow, M.13
-
63
-
-
0034624004
-
Growth regulation via p38 mitogen-activated protein kinase in developing liver
-
Awad, M. M.; Enslen, H.; Boylan, J. M.; Davis, R. J.; Gruppuso, P. A. Growth regulation via p38 mitogen-activated protein kinase in developing liver. J. Biol. Chem., 2000, 275, 38716-21.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 38716-38721
-
-
Awad, M.M.1
Enslen, H.2
Boylan, J.M.3
Davis, R.J.4
Gruppuso, P.A.5
-
64
-
-
0038390661
-
Involvement of the p38 mitogen-activated protein kinase cascade in hepatocellular carcinoma
-
Iyoda, K.; Sasaki, Y.; Horimoto, M.; Toyama, T.; Yakushijin, T.; Sakakibara, M.; Takehara, T.; Fujimoto, J.; Hori, M.; Wands, J. R.; Hayashi, N. Involvement of the p38 mitogen-activated protein kinase cascade in hepatocellular carcinoma. Cancer, 2003, 97, 3017-3026.
-
(2003)
Cancer
, vol.97
, pp. 3017-3026
-
-
Iyoda, K.1
Sasaki, Y.2
Horimoto, M.3
Toyama, T.4
Yakushijin, T.5
Sakakibara, M.6
Takehara, T.7
Fujimoto, J.8
Hori, M.9
Wands, J.R.10
Hayashi, N.11
-
65
-
-
18744396930
-
The manganese superoxide dismutase Ala16Val dimorphism modulates both mitochondrial import and mRNA stability
-
Sutton, A.; Imbert, A.; Igoudjil, A.; Descatoire, V.; Cazanave, S.; Pessayre, D.; Degoul, F. The manganese superoxide dismutase Ala16Val dimorphism modulates both mitochondrial import and mRNA stability. Pharmacogenet. Genomics, 2005, 15, 311-319.
-
(2005)
Pharmacogenet. Genomics
, vol.15
, pp. 311-319
-
-
Sutton, A.1
Imbert, A.2
Igoudjil, A.3
Descatoire, V.4
Cazanave, S.5
Pessayre, D.6
Degoul, F.7
-
66
-
-
16844379901
-
Manganese superoxide dismutase polymorphism, prediagnostic antioxidant status, and risk of clinical significant prostate cancer
-
Li, H.; Kantoff, P. W.; Giovannucci, E.; Leitzmann, M. F.; Gaziano, J. M.; Stampfer, M. J.; Ma, J. Manganese superoxide dismutase polymorphism, prediagnostic antioxidant status, and risk of clinical significant prostate cancer. Cancer Res., 2005, 65, 2498-2504.
-
(2005)
Cancer Res
, vol.65
, pp. 2498-2504
-
-
Li, H.1
Kantoff, P.W.2
Giovannucci, E.3
Leitzmann, M.F.4
Gaziano, J.M.5
Stampfer, M.J.6
Ma, J.7
-
68
-
-
35248826128
-
Genetic polymorphisms in the human selenoprotein P gene determine the response of selenoprotein markers to selenium supplementation in a gender-specific manner (the SELGEN study)
-
Meplan, C.; Crosley, L. K.; Nicol, F.; Beckett, G. J.; Howie, A. F.; Hill, K. E.; Horgan, G.; Mathers, J. C.; Arthur, J. R.; Hesketh, J. E. Genetic polymorphisms in the human selenoprotein P gene determine the response of selenoprotein markers to selenium supplementation in a gender-specific manner (the SELGEN study). FASEB J., 2007, 21, 3063-3074.
-
(2007)
FASEB J
, vol.21
, pp. 3063-3074
-
-
Meplan, C.1
Crosley, L.K.2
Nicol, F.3
Beckett, G.J.4
Howie, A.F.5
Hill, K.E.6
Horgan, G.7
Mathers, J.C.8
Arthur, J.R.9
Hesketh, J.E.10
-
69
-
-
57749099101
-
Interaction between single nucleotide polymorphisms in selenoprotein P and mitochondrial superoxide dismutase determines prostate cancer risk
-
Cooper, M. L.; Adami, H. O.; Gronberg, H.; Wiklund, F.; Green, F. R.; Rayman, M. P. Interaction between single nucleotide polymorphisms in selenoprotein P and mitochondrial superoxide dismutase determines prostate cancer risk. Cancer Res., 2008, 68, 10171-10177.
-
(2008)
Cancer Res
, vol.68
, pp. 10171-10177
-
-
Cooper, M.L.1
Adami, H.O.2
Gronberg, H.3
Wiklund, F.4
Green, F.R.5
Rayman, M.P.6
-
70
-
-
0035956482
-
ANT1, Twinkle, POLG, and TP: New genes open our eyes to ophthalmoplegia
-
Hirano, M.; DiMauro, S. ANT1, Twinkle, POLG, and TP: new genes open our eyes to ophthalmoplegia. Neurology, 2001, 57, 2163-2165.
-
(2001)
Neurology
, vol.57
, pp. 2163-2165
-
-
Hirano, M.1
DiMauro, S.2
-
71
-
-
0017378110
-
DNA polymerase of mitochondria is a gamma-polymerase
-
Bolden, A.; Noy, G. P.; Weissbach, A. DNA polymerase of mitochondria is a gamma-polymerase. J. Biol. Chem., 1977, 252, 3351-3356.
-
(1977)
J. Biol. Chem
, vol.252
, pp. 3351-3356
-
-
Bolden, A.1
Noy, G.P.2
Weissbach, A.3
-
72
-
-
0030587492
-
Cloning and characterization of the human mitochondrial DNA polymerase, DNA polymerase gamma
-
Ropp, P. A.; Copeland, W. C. Cloning and characterization of the human mitochondrial DNA polymerase, DNA polymerase gamma. Genomics, 1996, 36, 449-58.
-
(1996)
Genomics
, vol.36
, pp. 449-458
-
-
Ropp, P.A.1
Copeland, W.C.2
-
73
-
-
0035185070
-
Mutations at the mitochondrial DNA polymerase (POLG) locus associated with male infertility
-
Rovio, A. T.; Marchington, D. R.; Donat, S.; Schuppe, H. C.; Abel, J.; Fritsche, E.; Elliott, D. J.; Laippala, P.; Ahola, A. L.; McNay, D.; Harrison, R. F.; Hughes, B.; Barrett, T.; Bailey, D. M.; Mehmet, D.; Jequier, A. M.; Hargreave, T. B.; Kao, S. H.; Cummins, J. M.; Barton, D. E.; Cooke, H. J.; Wei, Y. H.; Wichmann, L.; Poulton, J.; Jacobs, H. T. Mutations at the mitochondrial DNA polymerase (POLG) locus associated with male infertility. Nat. Genet., 2001, 29, 261-262.
-
(2001)
Nat. Genet
, vol.29
, pp. 261-262
-
-
Rovio, A.T.1
Marchington, D.R.2
Donat, S.3
Schuppe, H.C.4
Abel, J.5
Fritsche, E.6
Elliott, D.J.7
Laippala, P.8
Ahola, A.L.9
McNay, D.10
Harrison, R.F.11
Hughes, B.12
Barrett, T.13
Bailey, D.M.14
Mehmet, D.15
Jequier, A.M.16
Hargreave, T.B.17
Kao, S.H.18
Cummins, J.M.19
Barton, D.E.20
Cooke, H.J.21
Wei, Y.H.22
Wichmann, L.23
Poulton, J.24
Jacobs, H.T.25
more..
-
74
-
-
54949136969
-
Association of the polymorphism of the CAG repeat in the mitochondrial DNA polymerase gamma gene (POLG) with testicular germ-cell cancer
-
Blomberg Jensen, M.; Leffers, H.; Petersen, J. H.; Daugaard, G.; Skakkebaek, N. E.; Rajpert-De Meyts, E. Association of the polymorphism of the CAG repeat in the mitochondrial DNA polymerase gamma gene (POLG) with testicular germ-cell cancer. Ann. Oncol., 2008, 19, 1910-1914.
-
(2008)
Ann. Oncol
, vol.19
, pp. 1910-1914
-
-
Blomberg Jensen, M.1
Leffers, H.2
Petersen, J.H.3
Daugaard, G.4
Skakkebaek, N.E.5
Rajpert-De Meyts, E.6
-
75
-
-
20044364344
-
-
Petros, J. A.; Baumann, A. K.; Ruiz-Pesini, E.; Amin, M. B.; Sun, C. Q.; Hall, J.; Lim, S.; Issa, M. M.; Flanders, W. D.; Hosseini, S. H.; Marshall, F. F.; Wallace, D. C. mtDNA mutations increase tumorigenicity in prostate cancer. Proc. Natl. Acad. Sci. USA, 2005, 102, 719-724.
-
Petros, J. A.; Baumann, A. K.; Ruiz-Pesini, E.; Amin, M. B.; Sun, C. Q.; Hall, J.; Lim, S.; Issa, M. M.; Flanders, W. D.; Hosseini, S. H.; Marshall, F. F.; Wallace, D. C. mtDNA mutations increase tumorigenicity in prostate cancer. Proc. Natl. Acad. Sci. USA, 2005, 102, 719-724.
-
-
-
-
76
-
-
0024448458
-
Human cells lacking mtDNA: Repopulation with exogenous mitochondria by complementation
-
King, M. P.; Attardi, G. Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementation. Science, 1989, 246, 500-503.
-
(1989)
Science
, vol.246
, pp. 500-503
-
-
King, M.P.1
Attardi, G.2
-
77
-
-
0034676227
-
Going APE over ref-1
-
Evans, A. R.; Limp-Foster, M.; Kelley, M. R. Going APE over ref-1. Mutat. Res., 2000, 461, 83-108.
-
(2000)
Mutat. Res
, vol.461
, pp. 83-108
-
-
Evans, A.R.1
Limp-Foster, M.2
Kelley, M.R.3
-
78
-
-
0031736203
-
Somatic mutations of the mitochondrial genome in human colorectal tumours
-
Polyak, K.; Li, Y.; Zhu, H.; Lengauer, C.; Willson, J. K.; Markowitz, S. D.; Trush, M. A.; Kinzler, K. W.; Vogelstein, B. Somatic mutations of the mitochondrial genome in human colorectal tumours. Nat. Genet., 1998, 20, 291-293.
-
(1998)
Nat. Genet
, vol.20
, pp. 291-293
-
-
Polyak, K.1
Li, Y.2
Zhu, H.3
Lengauer, C.4
Willson, J.K.5
Markowitz, S.D.6
Trush, M.A.7
Kinzler, K.W.8
Vogelstein, B.9
-
79
-
-
0032532559
-
Microsatellite instability in the mitochondrial DNA of colorectal carcinomas: Evidence for mismatch repair systems in mitochondrial genome
-
Habano, W.; Nakamura, S.; Sugai, T. Microsatellite instability in the mitochondrial DNA of colorectal carcinomas: evidence for mismatch repair systems in mitochondrial genome. Oncogene, 1998, 17, 1931-1937.
-
(1998)
Oncogene
, vol.17
, pp. 1931-1937
-
-
Habano, W.1
Nakamura, S.2
Sugai, T.3
-
80
-
-
0035476227
-
Identification of a mononucleotide repeat as a major target for mitochondrial DNA alterations in human tumors
-
Sanchez-Cespedes, M.; Parrella, P.; Nomoto, S.; Cohen, D.; Xiao, Y.; Esteller, M.; Jeronimo, C.; Jordan, R. C.; Nicol, T.; Koch, W. M.; Schoenberg, M.; Mazzarelli, P.; Fazio, V. M.; Sidransky, D. Identification of a mononucleotide repeat as a major target for mitochondrial DNA alterations in human tumors. Cancer Res. 2001, 61, 7015-7019.
-
(2001)
Cancer Res
, vol.61
, pp. 7015-7019
-
-
Sanchez-Cespedes, M.1
Parrella, P.2
Nomoto, S.3
Cohen, D.4
Xiao, Y.5
Esteller, M.6
Jeronimo, C.7
Jordan, R.C.8
Nicol, T.9
Koch, W.M.10
Schoenberg, M.11
Mazzarelli, P.12
Fazio, V.M.13
Sidransky, D.14
-
81
-
-
0032729633
-
Mitochondrial gene mutation, but not large-scale deletion, is a feature of colorectal carcinomas with mitochondrial microsatellite instability
-
Habano, W.; Sugai, T.; Yoshida, T.; Nakamura, S. Mitochondrial gene mutation, but not large-scale deletion, is a feature of colorectal carcinomas with mitochondrial microsatellite instability. Int. J. Cancer, 1999, 83, 625-629.
-
(1999)
Int. J. Cancer
, vol.83
, pp. 625-629
-
-
Habano, W.1
Sugai, T.2
Yoshida, T.3
Nakamura, S.4
-
82
-
-
0035886843
-
Detection of mitochondrial DNA mutations in primary breast cancer and fine-needle aspirates
-
Parrella, P.; Xiao, Y.; Fliss, M.; Sanchez-Cespedes, M.; Mazzarelli, P.; Rinaldi, M.; Nicol, T.; Gabrielson, E.; Cuomo, C.; Cohen, D.; Pandit, S.; Spencer, M.; Rabitti, C.; Fazio, V. M.; Sidransky, D. Detection of mitochondrial DNA mutations in primary breast cancer and fine-needle aspirates. Cancer Res., 2001, 61, 7623-7626.
-
(2001)
Cancer Res
, vol.61
, pp. 7623-7626
-
-
Parrella, P.1
Xiao, Y.2
Fliss, M.3
Sanchez-Cespedes, M.4
Mazzarelli, P.5
Rinaldi, M.6
Nicol, T.7
Gabrielson, E.8
Cuomo, C.9
Cohen, D.10
Pandit, S.11
Spencer, M.12
Rabitti, C.13
Fazio, V.M.14
Sidransky, D.15
-
83
-
-
34250624498
-
Frequency and phenotypic implications of mitochondrial DNA mutations in human squamous cell cancers of the head and neck
-
Zhou, S.; Kachhap, S.; Sun, W.; Wu, G.; Chuang, A.; Poeta, L.; Grumbine, L.; Mithani, S. K.; Chatterjee, A.; Koch, W.; Westra, W. H.; Maitra, A.; Glazer, C.; Carducci, M.; Sidransky, D.; McFate, T.; Verma, A.; Califano, J. A. Frequency and phenotypic implications of mitochondrial DNA mutations in human squamous cell cancers of the head and neck. Proc. Natl. Acad. Sci. USA, 2007, 104, 7540-7545.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 7540-7545
-
-
Zhou, S.1
Kachhap, S.2
Sun, W.3
Wu, G.4
Chuang, A.5
Poeta, L.6
Grumbine, L.7
Mithani, S.K.8
Chatterjee, A.9
Koch, W.10
Westra, W.H.11
Maitra, A.12
Glazer, C.13
Carducci, M.14
Sidransky, D.15
McFate, T.16
Verma, A.17
Califano, J.A.18
-
84
-
-
0039250954
-
Facile detection of mitochondrial DNA mutations in tumors and bodily fluids
-
Fliss, M. S.; Usadel, H.; Caballero, O. L.; Wu, L.; Buta, M. R.; Eleff, S. M.; Jen, J.; Sidransky, D. Facile detection of mitochondrial DNA mutations in tumors and bodily fluids. Science, 2000, 287, 2017-2019.
-
(2000)
Science
, vol.287
, pp. 2017-2019
-
-
Fliss, M.S.1
Usadel, H.2
Caballero, O.L.3
Wu, L.4
Buta, M.R.5
Eleff, S.M.6
Jen, J.7
Sidransky, D.8
-
85
-
-
0032838427
-
Loss of heteroplasmy in the displacement loop of brain mitochondrial DNA in astrocytic tumors
-
Kirches, E.; Michael, M.; Woy, C.; Schneider, T.; Warich-Kirches, M.; Schneider-Stock, R.; Winkler, K.; Wittig, H.; Dietzmann, K. Loss of heteroplasmy in the displacement loop of brain mitochondrial DNA in astrocytic tumors. Genes Chromosomes Cancer, 1999, 26, 80-83.
-
(1999)
Genes Chromosomes Cancer
, vol.26
, pp. 80-83
-
-
Kirches, E.1
Michael, M.2
Woy, C.3
Schneider, T.4
Warich-Kirches, M.5
Schneider-Stock, R.6
Winkler, K.7
Wittig, H.8
Dietzmann, K.9
-
86
-
-
0035882532
-
High frequency of mitochondrial DNA mutations in glioblastoma multiforme identified by direct sequence comparison to blood samples
-
Kirches, E.; Krause, G.; Warich-Kirches, M.; Weis, S.; Schneider, T.; Meyer-Puttlitz, B.; Mawrin, C.; Dietzmann, K. High frequency of mitochondrial DNA mutations in glioblastoma multiforme identified by direct sequence comparison to blood samples. Int. J. Cancer, 2001, 93, 534-538.
-
(2001)
Int. J. Cancer
, vol.93
, pp. 534-538
-
-
Kirches, E.1
Krause, G.2
Warich-Kirches, M.3
Weis, S.4
Schneider, T.5
Meyer-Puttlitz, B.6
Mawrin, C.7
Dietzmann, K.8
-
87
-
-
23944439689
-
Instability of mitochondrial DNA and MRI and clinical correlations in malignant gliomas
-
Montanini, L.; Regna-Gladin, C.; Eoli, M.; Albarosa, R.; Carrara, F.; Zeviani, M.; Bruzzone, M. G.; Broggi, G.; Boiardi, A.; Finocchiaro, G. Instability of mitochondrial DNA and MRI and clinical correlations in malignant gliomas. J. Neurooncol., 2005, 74, 87-89.
-
(2005)
J. Neurooncol
, vol.74
, pp. 87-89
-
-
Montanini, L.1
Regna-Gladin, C.2
Eoli, M.3
Albarosa, R.4
Carrara, F.5
Zeviani, M.6
Bruzzone, M.G.7
Broggi, G.8
Boiardi, A.9
Finocchiaro, G.10
-
88
-
-
0037270117
-
Mitochondrial DNA as a clonal tumor cell marker: Gliomatosis cerebri
-
Kirches, E.; Mawrin, C.; Schneider-Stock, R.; Krause, G.; Scherlach, C.; Dietzmann, K. Mitochondrial DNA as a clonal tumor cell marker: gliomatosis cerebri. J. Neurooncol., 2003, 61, 1-5.
-
(2003)
J. Neurooncol
, vol.61
, pp. 1-5
-
-
Kirches, E.1
Mawrin, C.2
Schneider-Stock, R.3
Krause, G.4
Scherlach, C.5
Dietzmann, K.6
-
89
-
-
0041742269
-
Detection of mitochondrial DNA mutations in the tumor and cerebrospinal fluid of medulloblastoma patients
-
Wong, L. J.; Lueth, M.; Li, X. N.; Lau, C. C.; Vogel, H. Detection of mitochondrial DNA mutations in the tumor and cerebrospinal fluid of medulloblastoma patients. Cancer Res., 2003, 63, 3866-3871.
-
(2003)
Cancer Res
, vol.63
, pp. 3866-3871
-
-
Wong, L.J.1
Lueth, M.2
Li, X.N.3
Lau, C.C.4
Vogel, H.5
-
90
-
-
0030951244
-
Tissue-specific selection for different mtDNA genotypes in heteroplasmic mice
-
Jenuth, J. P.; Peterson, A. C.; Shoubridge, E. A. Tissue-specific selection for different mtDNA genotypes in heteroplasmic mice. Nat. Genet., 1997, 16, 93-95.
-
(1997)
Nat. Genet
, vol.16
, pp. 93-95
-
-
Jenuth, J.P.1
Peterson, A.C.2
Shoubridge, E.A.3
-
91
-
-
0034109860
-
Microsatellite instability and mutation of mitochondrial and nuclear DNA in gastric carcinoma
-
Habano, W.; Sugai, T.; Nakamura, S. I.; Uesugi, N.; Yoshida, T.; Sasou, S. Microsatellite instability and mutation of mitochondrial and nuclear DNA in gastric carcinoma. Gastroenterology, 2000, 118, 835-841.
-
(2000)
Gastroenterology
, vol.118
, pp. 835-841
-
-
Habano, W.1
Sugai, T.2
Nakamura, S.I.3
Uesugi, N.4
Yoshida, T.5
Sasou, S.6
-
92
-
-
0034972303
-
High frequency of homoplasmic mitochondrial DNA mutations in human tumors can be explained without selection
-
Coller, H. A.; Khrapko, K.; Bodyak, N. D.; Nekhaeva, E.; Herrero-Jimenez, P.; Thilly, W. G. High frequency of homoplasmic mitochondrial DNA mutations in human tumors can be explained without selection. Nat. Genet., 2001, 28, 147-150.
-
(2001)
Nat. Genet
, vol.28
, pp. 147-150
-
-
Coller, H.A.1
Khrapko, K.2
Bodyak, N.D.3
Nekhaeva, E.4
Herrero-Jimenez, P.5
Thilly, W.G.6
-
93
-
-
0037242343
-
Mitochondrial DNA mutation correlates with stage progression and prognosis in non-small cell lung cancer
-
Matsuyama, W.; Nakagawa, M.; Wakimoto, J.; Hirotsu, Y.; Kawabata, M.; Osame, M. Mitochondrial DNA mutation correlates with stage progression and prognosis in non-small cell lung cancer. Hum. Mutat., 2003, 21, 441-443.
-
(2003)
Hum. Mutat
, vol.21
, pp. 441-443
-
-
Matsuyama, W.1
Nakagawa, M.2
Wakimoto, J.3
Hirotsu, Y.4
Kawabata, M.5
Osame, M.6
-
94
-
-
0030912190
-
Revisions in the International System for Staging Lung Cancer
-
Mountain, C. F. Revisions in the International System for Staging Lung Cancer. Chest, 1997, 111, 1710-1717.
-
(1997)
Chest
, vol.111
, pp. 1710-1717
-
-
Mountain, C.F.1
-
95
-
-
20644445442
-
Clinical value of mitochondrial mutations in colorectal cancer
-
Lievre, A.; Chapusot, C.; Bouvier, A. M.; Zinzindohoue, F.; Piard, F.; Roignot, P.; Arnould, L.; Beaune, P.; Faivre, J.; Laurent-Puig, P. Clinical value of mitochondrial mutations in colorectal cancer. J. Clin. Oncol., 2005, 23, 3517-3525.
-
(2005)
J. Clin. Oncol
, vol.23
, pp. 3517-3525
-
-
Lievre, A.1
Chapusot, C.2
Bouvier, A.M.3
Zinzindohoue, F.4
Piard, F.5
Roignot, P.6
Arnould, L.7
Beaune, P.8
Faivre, J.9
Laurent-Puig, P.10
-
96
-
-
0035992381
-
Mitochondrial C-tract alteration in premalignant lesions of the head and neck: A marker for progression and clonal proliferation
-
Ha, P. K.; Tong, B. C.; Westra, W. H.; Sanchez-Cespedes, M.; Parrella, P.; Zahurak, M.; Sidransky, D.; Califano, J. A. Mitochondrial C-tract alteration in premalignant lesions of the head and neck: a marker for progression and clonal proliferation. Clin. Cancer Res., 2002, 8, 2260-2265.
-
(2002)
Clin. Cancer Res
, vol.8
, pp. 2260-2265
-
-
Ha, P.K.1
Tong, B.C.2
Westra, W.H.3
Sanchez-Cespedes, M.4
Parrella, P.5
Zahurak, M.6
Sidransky, D.7
Califano, J.A.8
-
97
-
-
12144288294
-
Detection of LOH and mitochondrial DNA alterations in ductal lavage and nipple aspirate fluids from hngh-risk patients
-
Isaacs, C.; Cavalli, L. R.; Cohen, Y.; Pennanen, M.; Shankar, L. K.; Freedman, M.; Singh, B.; Liu, M.; Gallagher, A.; Rone, J. D.; Dickson, R. B.; Sidransky, D.; Haddad, B. R. Detection of LOH and mitochondrial DNA alterations in ductal lavage and nipple aspirate fluids from hngh-risk patients. Breast Cancer Res. Treat., 2004, 84, 99-105.
-
(2004)
Breast Cancer Res. Treat
, vol.84
, pp. 99-105
-
-
Isaacs, C.1
Cavalli, L.R.2
Cohen, Y.3
Pennanen, M.4
Shankar, L.K.5
Freedman, M.6
Singh, B.7
Liu, M.8
Gallagher, A.9
Rone, J.D.10
Dickson, R.B.11
Sidransky, D.12
Haddad, B.R.13
-
98
-
-
2442720182
-
The Human MitoChip: A high-throughput sequencing microarray for mitochondrial mutation detection
-
Maitra, A.; Cohen, Y.; Gillespie, S. E.; Mambo, E.; Fukushima, N.; Hoque, M. O.; Shah, N.; Goggins, M.; Califano, J.; Sidransky, D.; Chakravarti, A. The Human MitoChip: a high-throughput sequencing microarray for mitochondrial mutation detection. Genome Res., 2004, 14, 812-819.
-
(2004)
Genome Res
, vol.14
, pp. 812-819
-
-
Maitra, A.1
Cohen, Y.2
Gillespie, S.E.3
Mambo, E.4
Fukushima, N.5
Hoque, M.O.6
Shah, N.7
Goggins, M.8
Califano, J.9
Sidransky, D.10
Chakravarti, A.11
-
99
-
-
33748623364
-
An oligonucleotide microarray for high-throughput sequencing of the mitochondrial genome
-
Zhou, S.; Kassauei, K.; Cutler, D. J.; Kennedy, G. C.; Sidransky, D.; Maitra, A.; Califano, J. An oligonucleotide microarray for high-throughput sequencing of the mitochondrial genome. J. Mol. Diagn., 2006, 8, 476-482.
-
(2006)
J. Mol. Diagn
, vol.8
, pp. 476-482
-
-
Zhou, S.1
Kassauei, K.2
Cutler, D.J.3
Kennedy, G.C.4
Sidransky, D.5
Maitra, A.6
Califano, J.7
-
100
-
-
33846662128
-
Mitochondrial DNA mutations in preneoplastic lesions of the gastrointestinal tract: A biomarker for the early detection of cancer
-
Sui, G.; Zhou, S.; Wang, J.; Canto, M.; Lee, E. E.; Eshleman, J. R.; Montgomery, E. A.; Sidransky, D.; Califano, J. A.; Maitra, A. Mitochondrial DNA mutations in preneoplastic lesions of the gastrointestinal tract: a biomarker for the early detection of cancer. Mol. Cancer, 2006, 5, 73.
-
(2006)
Mol. Cancer
, vol.5
, pp. 73
-
-
Sui, G.1
Zhou, S.2
Wang, J.3
Canto, M.4
Lee, E.E.5
Eshleman, J.R.6
Montgomery, E.A.7
Sidransky, D.8
Califano, J.A.9
Maitra, A.10
-
101
-
-
55049125917
-
Performance of mitochondrial DNA mutations detecting early stage cancer
-
Jakupciak, J. P.; Maragh, S.; Markowitz, M. E.; Greenberg, A. K.; Hoque, M. O.; Maitra, A.; Barker, P. E.; Wagner, P. D.; Rom, W. N.; Srivastava, S.; Sidransky, D.; O'Connell, C. D. Performance of mitochondrial DNA mutations detecting early stage cancer. BMC Cancer, 2008, 8, 285.
-
(2008)
BMC Cancer
, vol.8
, pp. 285
-
-
Jakupciak, J.P.1
Maragh, S.2
Markowitz, M.E.3
Greenberg, A.K.4
Hoque, M.O.5
Maitra, A.6
Barker, P.E.7
Wagner, P.D.8
Rom, W.N.9
Srivastava, S.10
Sidransky, D.11
O'Connell, C.D.12
|