-
1
-
-
0001132883
-
-
Townsend, L. B., Ed., Plenum press: New York
-
Revankar, G. R., Robins, R. K. In Chemistry of nucleosides and nucleotides; Townsend, L. B., Ed., Plenum press: New York, 1991; p. 259.
-
(1991)
Chemistry of nucleosides and nucleotides
, pp. 259
-
-
Revankar, G.R.1
Robins, R.K.2
-
3
-
-
26644467502
-
-
Lin, W., Xu, K., Seela, F. Nucleosides Nucleotides Nucleic Acids 2005, 24, 869.
-
(2005)
Nucleosides Nucleotides Nucleic Acids
, vol.24
, pp. 869
-
-
Lin, W.1
Xu, K.2
Seela, F.3
-
5
-
-
0342509882
-
-
Hsu, T. C., Robins, R. K., Cheng, C. C. Science 1956, 123, 848.
-
(1956)
Science
, vol.123
, pp. 848
-
-
Hsu, T.C.1
Robins, R.K.2
Cheng, C.C.3
-
6
-
-
84961013102
-
-
Skipper, H. E., Robins, R. K., Thomson, J. R. Proc. Soc. Exptl. Biol. Med. 1955, 89, 594.
-
(1955)
Proc. Soc. Exptl. Biol. Med.
, vol.89
, pp. 594
-
-
Skipper, H.E.1
Robins, R.K.2
Thomson, J.R.3
-
10
-
-
84942832754
-
-
Fuerst, R., Somers, C. E., Hsu, T. C. J. Bacteriol. 1956, 72, 387.
-
(1956)
J. Bacteriol.
, vol.72
, pp. 387
-
-
Fuerst, R.1
Somers, C.E.2
Hsu, T.C.3
-
11
-
-
0345019095
-
-
Feigelson, P., Davidson, J. D., Robins, R. K. J. Biol. Chem. 1957, 226, 993.
-
(1957)
J. Biol. Chem.
, vol.226
, pp. 993
-
-
Feigelson, P.1
Davidson, J.D.2
Robins, R.K.3
-
12
-
-
0001700221
-
-
Skipper, H. E., Robins, R. K., Thomson, J. R., Cheng, C. C., Brokman, R. W., Schabel, F. M, Jr. Cancer Res. 1957, 17, 579.
-
(1957)
Cancer Res.
, vol.17
, pp. 579
-
-
Skipper, H.E.1
Robins, R.K.2
Thomson, J.R.3
Cheng, C.C.4
Brokman, R.W.5
Schabel, F.M.6
-
15
-
-
0000676124
-
-
Robins, R. K. J. Med. Chem. 1964, 7, 186, and references cited therein.
-
(1964)
J. Med. Chem
, vol.7
, pp. 186
-
-
Robins, R.K.1
-
16
-
-
0017191427
-
-
Hong, C. I., De, N. C., Tritsch, G. L., Chheda, G. B. J. Med. Chem. 1976, 19, 555.
-
(1976)
J. Med. Chem.
, vol.19
, pp. 555
-
-
Hong, C.I.1
De, N.C.2
Tritsch, G.L.3
Chheda, G.B.4
-
23
-
-
0006912385
-
-
Miyashita, A., Iijima, C., Higashino, T. Heterocycles 1990, 31, 1309.
-
(1990)
Heterocycles
, vol.31
, pp. 1309
-
-
Miyashita, A.1
Iijima, C.2
Higashino, T.3
-
24
-
-
2842555682
-
-
Inoue, S., Nagano, H., Nodiff, E. A., Saggiomo, A. J. J. Med. Chem. 1964, 7, 816.
-
(1964)
J. Med. Chem.
, vol.7
, pp. 816
-
-
Inoue, S.1
Nagano, H.2
Nodiff, E.A.3
Saggiomo, A.J.4
-
26
-
-
0017316415
-
-
Elnagdi, M. H., El-Moghayar, M. R., Fleita, D. H., Hafez, E. A., Fahmy, S. N. J. Org. Chem. 1976, 41, 3781.
-
(1976)
J. Org. Chem.
, vol.41
, pp. 3781
-
-
Elnagdi, M.H.1
El-Moghayar, M.R.2
Fleita, D.H.3
Hafez, E.A.4
Fahmy, S.N.5
-
29
-
-
0025338974
-
-
Tominaga, Y., Honkawa, Y., Hara, M., Hosomi, A. J. Heterocyclic Chem. 1990, 27, 775.
-
(1990)
Heterocyclic Chem.
, vol.27
, pp. 775
-
-
Tominaga, Y.1
Honkawa, Y.2
Hara, M.3
Hosomi, A.J.4
-
31
-
-
0000861979
-
-
Taylor, E. C., McKillop, A., Warverner, R. N. Tetrahedron 1967, 23, 891.
-
(1967)
Tetrahedron
, vol.23
, pp. 891
-
-
Taylor, E.C.1
McKillop, A.2
Warverner, R.N.3
-
32
-
-
84986535342
-
-
Tominaga, Y., Matsuoka, Y., Oniyama, Y., Uchimura, Y., Komiya, H., Hirayama, M., Kohra, S., Hosomi, A. J. Heterocycl. Chem. 1990, 27, 647.
-
(1990)
Heterocycl. Chem.
, vol.27
, pp. 647
-
-
Tominaga, Y.1
Matsuoka, Y.2
Oniyama, Y.3
Uchimura, Y.4
Komiya, H.5
Hirayama, M.6
Kohra, S.7
Hosomi, A.J.8
-
33
-
-
0142074846
-
-
Wu, T. Y. H., Schultz, P. G., Ding, S. Org. Lett. 2003, 5, 3587.
-
(2003)
Org. Lett.
, vol.5
, pp. 3587
-
-
Wu, T.Y.H.1
Schultz, P.G.2
Ding, S.3
-
34
-
-
33747584626
-
-
Heravi, M. M., Rajabzadeh, G., Bamoharram, F. F., Seifi, N. J. Mol.Catal. A-Chem. 2006, 256, 238.
-
(2006)
Mol.Catal. A-Chem.
, vol.256
, pp. 238
-
-
Heravi, M.M.1
Rajabzadeh, G.2
Bamoharram, F.F.3
Seifi, N.J.4
-
35
-
-
84981790584
-
-
Taylor, E. C., Vromen, S., Ravindranathan, R. V., McKillop, A. Angew. Chem., Int. Ed. Engl. 1966, 5, 308.
-
(1966)
Angew. Chem., Int. Ed. Engl.
, vol.5
, pp. 308
-
-
Taylor, E.C.1
Vromen, S.2
Ravindranathan, R.V.3
McKillop, A.4
-
36
-
-
0024360736
-
-
Deo, K., Pratap, R., Bhakuni, D. S. Ind. J. Chem. Sec. B 1989, 28B, 237.
-
(1989)
Ind. J. Chem. Sec. B
, vol.28B
, pp. 237
-
-
Deo, K.1
Pratap, R.2
Bhakuni, D.S.3
-
37
-
-
85043584360
-
-
Garg, N., Avasthi, K., Bhakuni, D. S. Synthesis 1989, 976.
-
(1989)
Synthesis
, pp. 976
-
-
Garg, N.1
Avasthi, K.2
Bhakuni, D.S.3
-
38
-
-
0030059735
-
-
Zacharie, B., Connolly, T. P., Rej, R., Attardo, G., Penney, C. L. Tetrahedron, 1996, 52, 2271.
-
(1996)
Tetrahedron
, vol.52
, pp. 2271
-
-
Zacharie, B.1
Connolly, T.P.2
Rej, R.3
Attardo, G.4
Penney, C.L.5
-
39
-
-
0037740664
-
-
Ali, A., Taylor, G. E., Ellsworth, K., Harris, G., Painter, R., Silver, L. L., Young, C. J. Med. Chem. 2003, 46, 1824.
-
(2003)
Med. Chem.
, vol.46
, pp. 1824
-
-
Ali, A.1
Taylor, G.E.2
Ellsworth, K.3
Harris, G.4
Painter, R.5
Silver, L.L.6
Young, C.J.7
-
40
-
-
23444440510
-
-
Da Settimo, F., Primofiore, G., La Motta, C., Taliani, S., Simorini, F., Marini, A. M., Mugnaini, L., Lavecchia, A., Novellino, E., Tuscano, D., Martini, C. J. Med. Chem. 2005, 48, 5162.
-
(2005)
Med. Chem.
, vol.48
, pp. 5162
-
-
Da Settimo, F.1
Primofiore, G.2
La Motta, C.3
Taliani, S.4
Simorini, F.5
Marini, A.M.6
Mugnaini, L.7
Lavecchia, A.8
Novellino, E.9
Tuscano, D.10
Martini, C.J.11
-
42
-
-
0038060520
-
-
Kim, D. C., Lee, Y. R., Yang, B., Shin, K. J., Kim, D. J., Chung, B. Y., Yoo, K. H. Bioorg. Med. Chem. 2003, 38, 525.
-
(2003)
Bioorg. Med. Chem.
, vol.38
, pp. 525
-
-
Kim, D.C.1
Lee, Y.R.2
Yang, B.3
Shin, K.J.4
Kim, D.J.5
Chung, B.Y.6
Yoo, K.H.7
-
43
-
-
1642316109
-
-
Devesa, I., Alcaraz, M. J., Riguera, R., Ferrándiz, M. L. Eur. J. Pharmacol. 2004, 488, 225.
-
(2004)
Eur. J. Pharmacol.
, vol.488
, pp. 225
-
-
Devesa, I.1
Alcaraz, M.J.2
Riguera, R.3
Ferrándiz, M.L.4
-
44
-
-
1942438497
-
-
Chern, J., Shia, K., Hsu, T., Lee, C., Lee, Y., Chang, C., Tseng, S., Shih, S. Bioorg. Med. Chem. Lett. 2004, 14, 2519.
-
(2004)
Bioorg. Med. Chem. Lett.
, vol.14
, pp. 2519
-
-
Chern, J.1
Shia, K.2
Hsu, T.3
Lee, C.4
Lee, Y.5
Chang, C.6
Tseng, S.7
Shih, S.8
-
45
-
-
32044468685
-
-
Holla, B. S., Mahalinga, M., Karthikeyan, M. S., Akberali, P. M., Shetty, N. S. Bioorg. Med. Chem. 2006, 14, 2040.
-
(2006)
Bioorg. Med. Chem.
, vol.14
, pp. 2040
-
-
Holla, B.S.1
Mahalinga, M.2
Karthikeyan, M.S.3
Akberali, P.M.4
Shetty, N.S.5
-
46
-
-
0026641583
-
-
Peet, N. P., Lentz, N. L., Sunder, S., Dudley, M. W., Odgen, A. M. L. J. Med. Chem. 1992, 35, 3263.
-
(1992)
J. Med. Chem.
, vol.35
, pp. 3263
-
-
Peet, N.P.1
Lentz, N.L.2
Sunder, S.3
Dudley, M.W.4
Odgen, A.M.L.5
-
47
-
-
85043599920
-
-
Quinn, R. J., Scammells, P. J., Tucker, D. J. Aust. J. Med. Chem. 1991, 44, 735.
-
(1991)
Aust. J. Med. Chem.
, vol.44
, pp. 735
-
-
Quinn, R.J.1
Scammells, P.J.2
Tucker, D.J.3
-
51
-
-
0033808290
-
-
Chebib, M., McKeveney, D., Quinn, R. J. Bioorg. Med. Chem. 2000, 8, 2581.
-
(2000)
Bioorg. Med. Chem.
, vol.8
, pp. 2581
-
-
Chebib, M.1
McKeveney, D.2
Quinn, R.J.3
-
52
-
-
0035931570
-
-
Poulsen, S. A., Young, D. J., Quinn, R. J. Bioorg. Med. Chem. Lett. 2001, 11, 191.
-
(2001)
Bioorg. Med. Chem. Lett.
, vol.11
, pp. 191
-
-
Poulsen, S.A.1
Young, D.J.2
Quinn, R.J.3
-
53
-
-
9844235351
-
-
Traxler, P., Bold, G., Frei, J., Lang, M., Lydon, N., Mett, H., Buchdunger, E., Meyer, T., Mueller, M., Furet, P. J. Med. Chem. 1997, 40, 3601.
-
(1997)
Med. Chem.
, vol.40
, pp. 3601
-
-
Traxler, P.1
Bold, G.2
Frei, J.3
Lang, M.4
Lydon, N.5
Mett, H.6
Buchdunger, E.7
Meyer, T.8
Mueller, M.9
Furet, P.J.10
-
55
-
-
36949004277
-
-
Schenone, S., Manetti, F., Botta, M. Anticancer Agents Med. Chem. 2007, 7, 660.
-
(2007)
Anticancer Agents Med. Chem.
, vol.7
, pp. 660
-
-
Schenone, S.1
Manetti, F.2
Botta, M.3
-
56
-
-
0030029143
-
-
Hanke, J. H., Gardner, J. P., Dow, R. L., Changelian, P. S., Brissette, W. H., Weringer, E. J., Pollok, B. A., Connelly, P. A. J. Biol. Chem. 1996, 271, 695.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 695
-
-
Hanke, J.H.1
Gardner, J.P.2
Dow, R.L.3
Changelian, P.S.4
Brissette, W.H.5
Weringer, E.J.6
Pollok, B.A.7
Connelly, P.A.8
-
57
-
-
0038813693
-
-
Tatton, L., Morley, G. M., Chopra, R., Khwaja, A. J. Biol. Chem. 2003, 278, 4847.
-
(2003)
Biol. Chem.
, vol.278
, pp. 4847
-
-
Tatton, L.1
Morley, G.M.2
Chopra, R.3
Khwaja, A.J.4
-
58
-
-
0032568055
-
-
Bishop, A. C., Shah, K., Liu, Y., Witucki, L., Kung, C., Shokat, K. M. Curr. Biol. 1998, 8, 257.
-
(1998)
Curr. Biol.
, vol.8
, pp. 257
-
-
Bishop, A.C.1
Shah, K.2
Liu, Y.3
Witucki, L.4
Kung, C.5
Shokat, K.M.6
-
59
-
-
0033518610
-
-
Bishop, A. C., Kung, C., Shah, K., Witucki, L., Shokat, K. M., Liu, Y. J. Am. Chem. Soc. 1999, 121, 627.
-
(1999)
Am. Chem. Soc.
, vol.121
, pp. 627
-
-
Bishop, A.C.1
Kung, C.2
Shah, K.3
Witucki, L.4
Shokat, K.M.5
Liu, Y.J.6
-
60
-
-
0037124207
-
-
Burchat, A. F., Calderwood, D. J., Friedman, M. M., Hirst, G. C., Li, B., Rafferty, P., Ritter, K., Skinner, B. S. Bioorg. Med. Chem. Lett. 2002, 12, 1687.
-
(2002)
Bioorg. Med. Chem. Lett.
, vol.12
, pp. 1687
-
-
Burchat, A.F.1
Calderwood, D.J.2
Friedman, M.M.3
Hirst, G.C.4
Li, B.5
Rafferty, P.6
Ritter, K.7
Skinner, B.S.8
-
61
-
-
11144354668
-
-
Borhani, D. W., Calderwood, D. J., Friedman, M. M., Hirst, G. C., Li, B., Leung, A. K. W., McRae, B., Ratnofsky, S., Ritter, K., Waegell, W. Bioorg. Med. Chem. Lett. 2004, 14, 2613.
-
(2004)
W., McRae, B., Ratnofsky, S., Ritter, K., Waegell, W. Bioorg. Med. Chem. Lett.
, vol.14
, pp. 2613
-
-
Borhani, D.W.1
Calderwood, D.J.2
Friedman, M.M.3
Hirst, G.C.4
Li, B.5
Leung, A.K.6
-
62
-
-
27744600732
-
-
Burchat, A., Borhani, D. W., Calderwood, D. J., Hirst, G. C., Li, B., Stachlewitz, R. F. Bioorg. Med. Chem. Lett. 2006, 16, 118.
-
(2006)
Bioorg. Med. Chem. Lett.
, vol.16
, pp. 118
-
-
Burchat, A.1
Borhani, D.W.2
Calderwood, D.J.3
Hirst, G.C.4
Li, B.5
Stachlewitz, R.F.6
-
63
-
-
33847770923
-
-
Schenone, S., Manetti, F., Botta, M. Mini Rev. Med. Chem. 2007, 7, 191.
-
(2007)
Mini Rev. Med. Chem.
, vol.7
, pp. 191
-
-
Schenone, S.1
Manetti, F.2
Botta, M.3
-
65
-
-
6344226300
-
-
Schenone, S., Bruno, O., Bondavalli, F., Ranise, A., Mosti, L., Menozzi, G., Fossa, P., Donnini, S., Santoro, A., Ziche, M., Manetti, F., Botta, M. Eur. J. Med. Chem. 2004, 39, 939.
-
(2004)
Eur. J. Med. Chem.
, vol.39
, pp. 939
-
-
Schenone, S.1
Bruno, O.2
Bondavalli, F.3
Ranise, A.4
Mosti, L.5
Menozzi, G.6
Fossa, P.7
Donnini, S.8
Santoro, A.9
Ziche, M.10
Manetti, F.11
Botta, M.12
-
66
-
-
11144355929
-
-
Schenone, S., Bruno, O., Ranise, A., Bondavalli, F., Brullo, C., Fossa, P., Mosti, L., Menozzi, G., Carraro, F., Naldini, A., Bernini, C., Manetti, F., Botta, M. Bioorg. Med. Chem. Lett. 2004, 14, 2511.
-
(2004)
Bioorg. Med. Chem. Lett.
, vol.14
, pp. 2511
-
-
Schenone, S.1
Bruno, O.2
Ranise, A.3
Bondavalli, F.4
Brullo, C.5
Fossa, P.6
Mosti, L.7
Menozzi, G.8
Carraro, F.9
Naldini, A.10
Bernini, C.11
Manetti, F.12
Botta, M.13
-
68
-
-
12144286142
-
-
Carraro, F., Pucci, A., Naldini, A., Schenone, S., Bruno, O., Ranise, A., Bondavalli, F., Brullo, C., Fossa, P., Menozzi, G., Mosti, L., Manetti, F., Botta, M. J. Med. Chem. 2004, 47, 1595.
-
(2004)
Med. Chem.
, vol.47
, pp. 1595
-
-
Carraro, F.1
Pucci, A.2
Naldini, A.3
Schenone, S.4
Bruno, O.5
Ranise, A.6
Bondavalli, F.7
Brullo, C.8
Fossa, P.9
Menozzi, G.10
Mosti, L.11
Manetti, F.12
Botta, M.J.13
-
69
-
-
33644869311
-
-
Carraro, F., Naldini, A., Pucci, A., Locatelli, G. A., Maga, G., Schenone, S., Bruno, O., Ranise, A., Bondavalli, F., Brullo, C., Fossa, P., Menozzi, G., Mosti, L., Modugno, M., Tintori, C., Manetti, F., Botta, M. J. Med. Chem. 2006, 49, 1549.
-
(2006)
Med. Chem.
, vol.49
, pp. 1549
-
-
Carraro, F.1
Naldini, A.2
Pucci, A.3
Locatelli, G.A.4
Maga, G.5
Schenone, S.6
Bruno, O.7
Ranise, A.8
Bondavalli, F.9
Brullo, C.10
Fossa, P.11
Menozzi, G.12
Mosti, L.13
Modugno, M.14
Tintori, C.15
Manetti, F.16
Botta, M.J.17
-
70
-
-
84921998272
-
-
Angelucci, A., Schenone, S., Gravina, G. L., Muzi, P., Festuccia, C., Vicentini, C., Botta, M., Bologna, M. Eur. J. Cancer 2006, 42, 2338.
-
(2006)
Eur. J. Cancer
, vol.42
, pp. 2338
-
-
Angelucci, A.1
Schenone, S.2
Gravina, G.L.3
Muzi, P.4
Festuccia, C.5
Vicentini, C.6
Botta, M.7
Bologna, M.8
-
71
-
-
33846827051
-
-
Donnini, S., Monti, M., Castagnini, C., Solito, R., Botta, M., Schenone, S., Giachetti, A., Ziche, M. Int. J. Cancer 2006, 120, 995.
-
(2006)
Int. J. Cancer
, vol.120
, pp. 995
-
-
Donnini, S.1
Monti, M.2
Castagnini, C.3
Solito, R.4
Botta, M.5
Schenone, S.6
Giachetti, A.7
Ziche, M.8
-
72
-
-
36148945220
-
-
Manetti, F., Santucci, A., Locatelli, G., Maga, G., Spreafico, A., Serchi, T., Orlandini, M., Bernardini, G., Caradonna, N. P., Spallarossa, A., Brullo, C., Schenone, S., Bruno, O., Ranise, A., Bondavalli, F., Hoffmann, O., Bologna, M., Angelucci, A., Botta, M. J. Med. Chem. 2007, 50, 5579.
-
(2007)
Med. Chem.
, vol.50
, pp. 5579
-
-
Manetti, F.1
Santucci, A.2
Locatelli, G.3
Maga, G.4
Spreafico, A.5
Serchi, T.6
Orlandini, M.7
Bernardini, G.8
Caradonna, N.P.9
Spallarossa, A.10
Brullo, C.11
Schenone, S.12
Bruno, O.13
Ranise, A.14
Bondavalli, F.15
Hoffmann, O.16
Bologna, M.17
Angelucci, A.18
Botta, M.J.19
-
73
-
-
41649110351
-
-
Manetti, F., Pucci, A., Magnani, M., Locatelli, G. A., Brullo, C., Naldini, A., Schenone, S., Maga, G., Carraro, F., Botta, M. ChemMedChem 2007, 2, 343.
-
(2007)
ChemMedChem
, vol.2
, pp. 343
-
-
Manetti, F.1
Pucci, A.2
Magnani, M.3
Locatelli, G.A.4
Brullo, C.5
Naldini, A.6
Schenone, S.7
Maga, G.8
Carraro, F.9
Botta, M.10
-
74
-
-
85043602600
-
-
Santucci, M. A; Corradi, V., Mancini, M., Manetti, F., Radi, M., Schenone, S., Botta, M. C-6 Unsubstituted Pyrazolo[3,4-d]Pyrimidines are Dual Src/Abl Inhibitors Effective Against Imatinib Mesylate-Resistant Chronic Myeloid Leukemia, Including that Arising from T315I Mutation, submitted for publication.
-
C-6 Unsubstituted Pyrazolo[3,4-d]Pyrimidines are Dual Src/Abl Inhibitors Effective Against Imatinib Mesylate-Resistant Chronic Myeloid Leukemia, Including that Arising from T315I Mutation, submitted for publication.
-
-
Santucci M.A1
Corradi, V.2
Mancini, M.3
Manetti, F.4
Radi, M.5
Schenone, S.6
Botta, M.7
-
75
-
-
27544453151
-
-
Meyn III, M. A., Schreiner, S. J., Dumitrescu, T. P., Nau, G. J., Smithgall, T. E. Mol. Pharmacol. 2005, 68, 1320.
-
(2005)
Mol. Pharmacol.
, vol.68
, pp. 1320
-
-
Meyn, M.A.1
Schreiner, S.J.2
Dumitrescu, T.P.3
Nau, G.J.4
Smithgall, T.E.5
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