D-Serine exposure resulted in gene expression changes implicated in neurodegenerative disorders and neuronal dysfunction in male Fischer 344 rats

Archives of Toxicology

Volumn 83, Issue 8, 2009, Pages 747-762

  Davidson, Molly E ^a,c   Kerepesi, Laura A ^b   Soto, Armando ^c   Chan, Victor T ^c  

^a OAK RIDGE INSTITUTE FOR SCIENCE AND EDUCATION   (United States)

^b BATTELLE MEMORIAL INSTITUTE   (United States)

^c AIR FORCE RESEARCH LABORATORY   (United States)

Author keywords

D Serine; N methyl d aspartate (NMDA) receptor; Neuronal dysfunction; Pathway analysis; Transcriptomic profiling

Indexed keywords

ACTIN; DEXTRO SERINE; GLYCINE; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; INSULIN; INTERLEUKIN 2; INTERLEUKIN 3; INTERLEUKIN 5; INTERLEUKIN 6; MAX PROTEIN; MYC PROTEIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PROTEASOME; PROTEIN TAF1; TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR ALPHA; UBIQUITIN CONJUGATING ENZYME; UNCLASSIFIED DRUG; WNT PROTEIN; SERINE;

ACTIN POLYMERIZATION; ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DDX3X GENE; DEGENERATIVE DISEASE; ENDOCYTOSIS; EPILEPSY; EXCITOTOXICITY; FISCHER 344 RAT; FOCAL ADHESION; FOREBRAIN; GENE; GENE CONTROL; GENE EXPRESSION; INJURY; ISCHEMIA; MALE; MICROARRAY ANALYSIS; NERVE CELL NECROSIS; NEUROLOGIC DISEASE; NONHUMAN; PRIORITY JOURNAL; RAT; RNA METABOLISM; RNA PROCESSING; RNA SPLICING; SCHIZOPHRENIA; SIGNAL TRANSDUCTION; TRANSPORT VESICLE; UBE2D GENE; UBQ1N1 GENE; ANIMAL; DNA MICROARRAY; DRUG EFFECT; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; METABOLISM; NERVE CELL; PHYSIOLOGY;

RATTUS;

ANIMALS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORKS; MALE; NEURONS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROSENCEPHALON; RATS; RATS, INBRED F344; SERINE; SIGNAL TRANSDUCTION;

EID: 68149162196     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-009-0405-3     Document Type: Article

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