Immunolocalization and redistribution of the FAC1 protein in Alzheimer's disease

Journal of Neuropathology and Experimental Neurology

Volumn 55, Issue 4, 1996, Pages 444-454

  Schoonover, Susan ^a   Davies, Peter ^b   Bowser, Robert ^a,c  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^c PRESBYTERIAN UNIVERSITY HOSPITAL   (United States)

Author keywords

Alzheimer's disease; Amyloid plaques; Dendrites; Hippocampus; Immunolocalization; Neocortex; Neurofibrillary tangles

Indexed keywords

BRAIN PROTEIN; MONOCLONAL ANTIBODY;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; BRAIN BIOPSY; ENTORHINAL CORTEX; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; NEUROFIBRILLARY TANGLE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PYRAMIDAL NERVE CELL; SENILE PLAQUE; TISSUE DISTRIBUTION;

EID: 0029880910     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005072-199604000-00007     Document Type: Article

References (28)

1. Bowser R, Giambrone A, Davies P. FAC1, a novel gene identified with the monoclonal antibody Alz50, is developmentally regulated in human brain. Develop Neurosci 1995;17:20-37
2. Wolozin BL, Pruchnicki A, Dickson DW, Davies P. A neuronal antigen in the brains of Alzheimer patients. Science 1986;232:648-50
3. Ksiezak-Reding H, Davies P, Yen S-H. Alz 50, a monoclonal antibody to Alzheimer's disease antigen, cross-reacts with tau proteins from bovine and normal human brain. J Biol Chem 1988;263:7943-47
4. Ksiezak-Reding H, Binder LI, Yen S-H. Immunochemical and biochemical characterization of tau proteins in normal and Alzheimer's disease brains with Alz-50 and Tau-1. J Biol Chem 1988;263:7948-53
5. St George-Hyslop PH. The molecular genetics of Alzheimer's disease. In: Terry RD, Katzman R, Bick KL, eds. Alzheimer Disease. New York: Raven Press, Ltd, 1994:345-52
6. Cras P, Kawai M, Lowery D, Gonzalez-DeWhitt P, Greenberg B, Perry G. Senile plaque neuntes in Alzheimer disease accumulate amyloid precursor protein. Proc Natl Acad Sci USA 1991;88:7552-56
7. Masliah E, Mallory M, Hansen L, et al. Patterns of aberrant sprouting in Alzheimer's disease. Neuron 1991;6:729-39
8. Perry G, Friedman R, Shaw G, Chau V. Ubiquitin is detected in neurofibrillary tangles and senile plaque neuntes of Alzheimer's brain. Proc Natl Acad Sci USA 1987;84:3033-36
9. Abraham CR, Selkoe DJ, Potter H. Immunochemical identification of the serine protease inhibitor α1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease. Cell 1988;52:487-501
10. Namba Y, Tomonaga M, Kawasaki H, Otoma E, Ikeda K. Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and Kuro plaque amyloid in Creutzfelt-Jakob disease. Brain Res 1991;541:163-66
11. Han S-H, Einstein G, Weisgraber KH, Strittmatter WJ, et al. Apolipoprotein E is localized to the cytoplasm of human cortical neurons: A light and electron microscopic study. J Neuropath Exp Neurol 1994;53:535-44
12. Griffin WST, Sheng JG, Roberts GW, Mrak RE. Interleukin-1 expression in different plaque types in Alzheimer's disease: Significance in plaque evolution. J Neuropathol Exp Neurol 1995;54:276-81
13. Snow AJD, Mar H, Nochlin D, et al. The presence of heparan sulfate proteoglycans in the neuritic plaques and congophilic angiopathy in Alzheimer's disease. Am J Pathol 1988;133:456-63
14. Braak H, Braak E. Neuropathological stagcing of Alzheimer-related changes. Acta Neuropathol 1991;82:239-59
15. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of proteindye binding. Anal Biochem 1976;72:248-54
16. Goldman JE. The association of actin with Hirano bodies. J Neuropathol Exp Neurol 1983;42:146-52
17. Schmidt ML, Lee VM-Y, Trojanowski JQ. Analysis of epitopes shared by Hirano bodies and neurofilament proteins in normal and Alzheimer's disease hippocampus. Lab Invest 1989;60:513-22
18. Tucker RP, Binder LI, Viereck C, Hemmings BA, Matus A. The sequential appearance of low- and high-molecular weight forms of MAP2 in the developing cerebellum. J Neuroscience 1988;8:4503-12
19. Scheibel AB, Tomiyasu U. Dendritic sprouting in Alzheimer's presenile dementia. Exp Neurol 1978;80:1-8
20. Hyman BT, Kromer LJ, Van Hoesen GW. Reinnervation of the hippocampal perforant pathway zone in Alzheimer's disease. Ann Neurol 1987;21:259-67
21. McKee AC, Kowall NW, Kosik KS. Microtubular reorganization and dendritic growth response in Alzheimer's disease. Ann Neurol 1989;26:652-59
22. Dickson DW, Crystal HA, Bevona C, Honer WH, Vincent IJ, Davies P. Correlations of synaptic and pathologic markers with cognition of the elderly. Neurobiol Aging 1995;16:285-98
23. Masliah, E, Mallory M, Alford M, Hansen LA, Saitoh T. Immunoreactivity of the nuclear antigen p105 is associated with plaques and tangles in Alzheimer's disease. Lab Invest 1993;69:562-69
24. Smith TW, Lippa CF. Ki-67 immunoreactivity in Alzheimer's disease and other neurodegenerative disorders. J Neuropathol Exp Neurol 1995;54:297-303
25. Shoji M, Hirai S, Yamaguchi ZH, Harigaya Y, Kawarabayashi T. Amyloid β-protein precursor accumulates in dystrophic neurites of senile plaques in Alzheimer-type dementia. Brain Res 1990;512: 164-68
26. Bauer J, Strauss S, Schreiter-Gasser U, et al. Interleukin-6 and α-2-macroglobulin indicate an acute-phase state in Alzheimer's disease cortices. FEBS Lett 1991;285:111-14
27. Berkenbosch F, Biewenga J, Brouns M, Rozemuller JM, Strijbos P, van Dam AM. Cytokines and inflammatory proteins in Alzheimer's disease. Res Immunol 1992;143:657-63
28. Zhan S-S, Kamphorst W, Van Nostrand WE, Eikelenboom P. Distribution of neuronal growth-promoting factors and cytoskeletal proteins in altered neurites in Alzheimer's disease and non-demented elderly. Acta Neuropathol 1995;89:356-62